Pringle of Scotland是一家老牌的羊绒制品商,其发明的多色菱形花纹非常有名。在这次项目当中,Pringle要求atelierotT作室为他们即将上线的时装精品店做一个全新的设计。该店坐落于伦敦最负盛名的街道之一MountStreet,Pringle精品店...Pringle of Scotland是一家老牌的羊绒制品商,其发明的多色菱形花纹非常有名。在这次项目当中,Pringle要求atelierotT作室为他们即将上线的时装精品店做一个全新的设计。该店坐落于伦敦最负盛名的街道之一MountStreet,Pringle精品店外观选用历史悠久的维多利亚式红砖建造而成,完美地诠释了该品牌悠长的苏格兰历史,而室内则被设计成反映品牌现代化与革新精神的时尚体验空间。展开更多
Ringing, i.e. the emergence of an oscillatory tail behind a wave pulse as it propagates through a medium, is a pervasive artefact in FE and FDTD calculated waveforms. It is known to be a consequence of numerical dispe...Ringing, i.e. the emergence of an oscillatory tail behind a wave pulse as it propagates through a medium, is a pervasive artefact in FE and FDTD calculated waveforms. It is known to be a consequence of numerical dispersion arising from the discretization of the equations of motion. The use of an irregular mesh in a FE code has the further consequence of rendering the displacement field increasingly noisy with distance behind the wave front. In this paper these effects are illustrated using the commercial FE package ABAQUS with square and irregular triangular meshes to calculate the progress of a longitudinally polarized Ricker pulse along the axis of a cylindrically shaped aluminium specimen. We are able to give a precise analytical account of the evolution of ringing on the basis of a low order approximation for the dispersion relation of the discretized equations of motion. A qualitative account is provided of the generation of noise in the use of an irregular triangular mesh.展开更多
Voriconazole is increasingly used as a first-line agent for empirical antifungal therapy of prolonged febrile neutropenia in paediatric cancer patients. We describe the case of a 9-yearold patient with stage IV Burkit...Voriconazole is increasingly used as a first-line agent for empirical antifungal therapy of prolonged febrile neutropenia in paediatric cancer patients. We describe the case of a 9-yearold patient with stage IV Burkitt lymphoma, who developed pulmonary and splenic zygomycosis while receiving voriconazole for persistent febrile neutropenia. The causative agent, Absidia corymbifera,was identified by broad-range fungalPCR in a lung biopsy sample. The patient was successfully treated with a combination of partial resection of the left upper lobe and antifungal therapy with high-dose liposomal amphotericin B followed by oral itraconazole as demonstrated by resolving pulmonary infiltrates on serial high resolution CT scans. Conclusion: This case emphasises that the lack of in vitro activity of voriconazole against zygomycetes is clinically relevant. Failure of voriconazole in suspected fungal infection should be investigated for the possibility of zygomycosis. Broad-range polymerase chain reaction may be able to identify the causative organism when cultures remain sterile.展开更多
文摘Pringle of Scotland是一家老牌的羊绒制品商,其发明的多色菱形花纹非常有名。在这次项目当中,Pringle要求atelierotT作室为他们即将上线的时装精品店做一个全新的设计。该店坐落于伦敦最负盛名的街道之一MountStreet,Pringle精品店外观选用历史悠久的维多利亚式红砖建造而成,完美地诠释了该品牌悠长的苏格兰历史,而室内则被设计成反映品牌现代化与革新精神的时尚体验空间。
文摘Ringing, i.e. the emergence of an oscillatory tail behind a wave pulse as it propagates through a medium, is a pervasive artefact in FE and FDTD calculated waveforms. It is known to be a consequence of numerical dispersion arising from the discretization of the equations of motion. The use of an irregular mesh in a FE code has the further consequence of rendering the displacement field increasingly noisy with distance behind the wave front. In this paper these effects are illustrated using the commercial FE package ABAQUS with square and irregular triangular meshes to calculate the progress of a longitudinally polarized Ricker pulse along the axis of a cylindrically shaped aluminium specimen. We are able to give a precise analytical account of the evolution of ringing on the basis of a low order approximation for the dispersion relation of the discretized equations of motion. A qualitative account is provided of the generation of noise in the use of an irregular triangular mesh.
文摘Voriconazole is increasingly used as a first-line agent for empirical antifungal therapy of prolonged febrile neutropenia in paediatric cancer patients. We describe the case of a 9-yearold patient with stage IV Burkitt lymphoma, who developed pulmonary and splenic zygomycosis while receiving voriconazole for persistent febrile neutropenia. The causative agent, Absidia corymbifera,was identified by broad-range fungalPCR in a lung biopsy sample. The patient was successfully treated with a combination of partial resection of the left upper lobe and antifungal therapy with high-dose liposomal amphotericin B followed by oral itraconazole as demonstrated by resolving pulmonary infiltrates on serial high resolution CT scans. Conclusion: This case emphasises that the lack of in vitro activity of voriconazole against zygomycetes is clinically relevant. Failure of voriconazole in suspected fungal infection should be investigated for the possibility of zygomycosis. Broad-range polymerase chain reaction may be able to identify the causative organism when cultures remain sterile.