AIM: To evaluate different methods in differentiating idiopathic neonatal hepatitis from biliary atresia. METHODS: Sixty-five infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis and ...AIM: To evaluate different methods in differentiating idiopathic neonatal hepatitis from biliary atresia. METHODS: Sixty-five infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis and biliary atresia were studied prospectively from September 2003 to March 2006. A thorough history and physical examination were undertaken and the liver enzymes were examined. All cases underwent abdominal ultrasonography, hepatobiliary scintigraphy, and percutaneous liver biopsy. The accuracy, sensitivity, specificity and predictive values of these various methods were compared. RESULTS: There were 34 girls and 31 boys, among them 46 subjects had idiopathic neonatal hepatitis (age, 61 ± 17 d) and 19 had biliary atresia (age, 64 ± 18 d). The mean age at onset of jaundice was significantly lower in cases of biliary atresia when compared to idiopathic neonatal hepatitis cases (9 ± 13 d vs 20 ± 21 d; P = 0.032). The diagnostic accuracy of different methods was as follows: liver biopsy, 96.9%; clinical evaluation, 70.8%; ultrasonography, 69.2%; hepatobiliary scintigraphy, 58.5%; and liver enzymes, 50.8%.CONCLUSION: Our results indicate that clinical evaluation by an experienced pediatric hepatologist and a biopsy of the liver are considered as the most reliable methods to differentiate idiopathic neonatal hepatitis and biliary atresia.展开更多
Carbon quantum dots （CQDs） have emerged as potential alternatives to classical metal-based semiconductor quantum dots （QDs） due to the abundance of their precursors, their ease of synthesis, high biocompatibility,...Carbon quantum dots （CQDs） have emerged as potential alternatives to classical metal-based semiconductor quantum dots （QDs） due to the abundance of their precursors, their ease of synthesis, high biocompatibility, low cost, and particularly their strong photoresponsiveness, tunability, and stability. Light is a versatile, tunable stimulus that can provide spatiotemporal control. Its interaction with CQDs elicits interesting responses such as wavelength-dependent optical emissions, charge/electron transfer, and heat generation, processes that are suitable for a range of photomediated bioapplications. The carbogenic core and surface characteristics of CQDs can be tuned through versatile engineering strategies to endow specific optical and physicochemical properties, while conjugation with specific moieties can enable the design of targeted probes. Fundamental approaches to tune the responses of CQDs to photo-interactions and the design of bionanoprobes are presented, which enable biomedical applications involving diagnostics and therapeutics. These strategies represent comprehensive platforms for engineering multifunctional probes for nanomedicine, and the design of QD probes with a range of metal-free and emer^in~ 2D materials.展开更多
AIM： To evaluate the clinical presentation, response to prophylactic therapy and outcome of children with cyclic vomiting syndrome （CVS） in Shiraz, Iran. METHODS： During a period of 11 years （March 1994 to March ...AIM： To evaluate the clinical presentation, response to prophylactic therapy and outcome of children with cyclic vomiting syndrome （CVS） in Shiraz, Iran. METHODS： During a period of 11 years （March 1994 to March 2005）, 181 consecutive children with a final diagnosis of CVS were evaluated, treated and followed in our center. Patients were randomized to receive either amitriptyline or propranolol as prophylactic treatments. RESULTS： There were 88 boys and 93 girls with mean age of onset of symptoms of 4.9 ± 3.3 years （range, neonatal period to 14 years）, the mean age at final diagnosis was 6.9 years （range, 1.5 to 14）, and the mean duration between the onset of the first attack and the final diagnosis of CVS was 2 ± 1.81 years （range, 1/6 to 8）. The mean duration of each attack was 4.26 days （range, from few hours to 10 d） and the mean interval between the attacks was 1.8 mo （range, 1 wk to 12 too）. The time of onset of the attacks was midnight to early morning in about 70% of cases. Amitriptyline was effective in 46 out of 81 （56%） patients （P 〈 0.001）. Propranolol appeared to have a superior action and was effective in 74 out of 83 （92%） patients （P 〈 0.0001）. CONCLUSION： There is a significant lag time between the onset of clinical symptoms and the final diagnosis of CVS in our area. In patients with typical clinical presentations of CVS, who are examined by an experienced physician, invasive workup is not necessary. Propranolol appears more effective than arnitriptyline for prophylactic use in children with CVS.展开更多
Surface roughness and shape play an important role on the behavior of particles in various processes such as flotation. In this re- search, the influence of different grinding methods on the surface roughness and shap...Surface roughness and shape play an important role on the behavior of particles in various processes such as flotation. In this re- search, the influence of different grinding methods on the surface roughness and shape characteristics of quartz particles as well as the effect of these parameters on the flotation of the particles was investigated. The surface roughness of the particles was determined by measuring their specific surface area via the gas adsorption method. The shape characteristics of the particles were measured and calculated by images obtained by scanning electron microscopy via an image analysis system. The flotation kinetics was determined using a laboratory flotation cell. The results showed that the particles of rod mill products have higher roughness and elongation ratio and lower roundness than the parti- cles of ball mill products. The flotation kinetics constant of the particles increased with their surface roughness increasing. Particles with higher elongation and lower roundness indicated higher floatability. In addition, the influence of the surface roughness on the flotation kinet- ics was greater than that of shape parameters.展开更多
Due to nonlinear behavior of power production of photovoltaic(PV)systems,it is necessary to apply the maximum power point tracking(MPPT)techniques to generate the maximum power.The conventional MPPT methods do not fun...Due to nonlinear behavior of power production of photovoltaic(PV)systems,it is necessary to apply the maximum power point tracking(MPPT)techniques to generate the maximum power.The conventional MPPT methods do not function properly in rapidly changing atmospheric conditions.In this study,a fuzzy logic controller(FLC)optimized by a combination of particle swarm optimization(PSO)and genetic algorithm(GA)is proposed to obtain the maximum power point(MPP).The proposed FLC uses the ratio of power variations to voltage variations and the derivative of power variations to voltage variations as inputs and uses the duty cycle as the output.The range of changes in fuzzy membership functions and fuzzy rules are proposed as an optimization problem optimized by the PSO-GA.The proposed design is validated for MPPT of a PV system using MATLAB/Simulink software.The results indicate a better performance of the proposed FLC compared to the common methods.展开更多
This research presents a novel nature-inspired metaheuristic algorithm called Frilled Lizard Optimization(FLO),which emulates the unique hunting behavior of frilled lizards in their natural habitat.FLO draws its inspi...This research presents a novel nature-inspired metaheuristic algorithm called Frilled Lizard Optimization(FLO),which emulates the unique hunting behavior of frilled lizards in their natural habitat.FLO draws its inspiration from the sit-and-wait hunting strategy of these lizards.The algorithm’s core principles are meticulously detailed and mathematically structured into two distinct phases:(i)an exploration phase,which mimics the lizard’s sudden attack on its prey,and(ii)an exploitation phase,which simulates the lizard’s retreat to the treetops after feeding.To assess FLO’s efficacy in addressing optimization problems,its performance is rigorously tested on fifty-two standard benchmark functions.These functions include unimodal,high-dimensional multimodal,and fixed-dimensional multimodal functions,as well as the challenging CEC 2017 test suite.FLO’s performance is benchmarked against twelve established metaheuristic algorithms,providing a comprehensive comparative analysis.The simulation results demonstrate that FLO excels in both exploration and exploitation,effectively balancing these two critical aspects throughout the search process.This balanced approach enables FLO to outperform several competing algorithms in numerous test cases.Additionally,FLO is applied to twenty-two constrained optimization problems from the CEC 2011 test suite and four complex engineering design problems,further validating its robustness and versatility in solving real-world optimization challenges.Overall,the study highlights FLO’s superior performance and its potential as a powerful tool for tackling a wide range of optimization problems.展开更多
The presence of Hg in the aqueous media is known to cause severe health issues in both humans and animals.Many technologies and especially adsorbents have been applied for its removal. In this study, a graphene oxide...The presence of Hg in the aqueous media is known to cause severe health issues in both humans and animals.Many technologies and especially adsorbents have been applied for its removal. In this study, a graphene oxide–carbon composite(GO–CC) as a new adsorbent was prepared by sol gel procedure and characterized using field emission scanning electron microscopy, BET and EDX. The effects of different variables including solution p H, contact time, adsorbent dose and GO ratio in adsorbent matrix on the removal capacity of Hg were studied. The isotherm data correlated well with the Langmuir isotherm model. Further analysis recommended that the Hg^(2+) adsorption process is governed by the intra-particle and external mass transfer, in which the film diffusion was the rate restrictive step. The presented composite has maximum absorption capacity, q_(max) of 68.8 mg·g^(-1), which is comparable with carbon based adsorbent reported in the previous publications.展开更多
Objective: To investigate and predict the effects of climate change on the potential distribution of the main vector and reservoir hosts of the disease in Yazd province in the future.Methods: Distribution data for vec...Objective: To investigate and predict the effects of climate change on the potential distribution of the main vector and reservoir hosts of the disease in Yazd province in the future.Methods: Distribution data for vector and reservoir hosts of zoonotic cutaneous leishmaniasis in Yazd province were obtained from earlier studies conducted in the area.MaxEnt ecological niche modeling was used to predict environmental suitability.BCC-CSM1-1(m) model and two climate change scenarios, RCP 4.5 and RCP 8.5 were used for horizons 2030 and 2050 climate projections.Future projections were based on data of a regional climate change model.Results: With both scenarios in 2030 and 2050, the results of jackknife test indicated that the mean temperature of wettest quarter and temperature annual range had the greatest effect on the model for the vector and the reservoir hosts, respectively.Conclusions: The climate conditions are the major determinants of zoonotic cutaneous leishmaniasis incidence rate in Yazd Province.These climate conditions provide favorable habitats for ease transmission of zoonotic cutaneous leishmaniasis in this endemic area.Habitats suitability for the vector and reservoir will be expanding in the coming years compared with the current conditions, such that, in horizon 2030 & 2050, the probability of the presence of the vector and reservoir within 38 580 and 37 949 km^2, respectively, from Yazd province is above 60%.Moreover, an increase is predicted in the presence of the vector in the western parts and the reservoir in the northern and central parts of the province in the future.Understanding the role of environmental and bioclimatic factors in zoonotic cutaneous leishmaniasis occurrence can provide a guide for policy-makers in the creation and implementation of more effective policies for prevention and control.展开更多
Pulmonary fibrosis, a chronic inflammatory disease that occurs mainly in older adults, is a serious health threat with few effective treatment options. The etiological aspects of pulmonary fibrosis remain unknown, tho...Pulmonary fibrosis, a chronic inflammatory disease that occurs mainly in older adults, is a serious health threat with few effective treatment options. The etiological aspects of pulmonary fibrosis remain unknown, though some factors such as cigarette smoking, viral infections, surfactant protein polymorphisms, and chronic or high doses use of certain drugs are considered to be risk factors for the progression of pulmonary fibrosis. No standard treatments have been introduced in clinic yet. Although glucocorticoids and antioxidant drugs have been administered, the severe and broad-spectrum adverse effects of glucocorticoids limit their use. Efforts to identify novel therapeutic agents with improved safety profiles are therefore ongoing. In this review, the authors have described the effects of herbal extracts and compounds and certain pharmacological agents on pulmonary fibrosis in animal models. These effects indicate that herbs are a promising source of compounds that can play pivotal roles in the treatment of lung fibrosis.展开更多
The efficiency of businesses is often hindered by the challenges encountered in traditional Supply Chain Manage-ment(SCM),which is characterized by elevated risks due to inadequate accountability and transparency.To a...The efficiency of businesses is often hindered by the challenges encountered in traditional Supply Chain Manage-ment(SCM),which is characterized by elevated risks due to inadequate accountability and transparency.To address these challenges and improve operations in green manufacturing,optimization algorithms play a crucial role in supporting decision-making processes.In this study,we propose a solution to the green lot size optimization issue by leveraging bio-inspired algorithms,notably the Stork Optimization Algorithm(SOA).The SOA draws inspiration from the hunting and winter migration strategies employed by storks in nature.The theoretical framework of SOA is elaborated and mathematically modeled through two distinct phases:exploration,based on migration simulation,and exploitation,based on hunting strategy simulation.To tackle the green lot size optimization issue,our methodology involved gathering real-world data,which was then transformed into a simplified function with multiple constraints aimed at optimizing total costs and minimizing CO_(2) emissions.This function served as input for the SOA model.Subsequently,the SOA model was applied to identify the optimal lot size that strikes a balance between cost-effectiveness and sustainability.Through extensive experimentation,we compared the performance of SOA with twelve established metaheuristic algorithms,consistently demonstrating that SOA outperformed the others.This study’s contribution lies in providing an effective solution to the sustainable lot-size optimization dilemma,thereby reducing environmental impact and enhancing supply chain efficiency.The simulation findings underscore that SOA consistently achieves superior outcomes compared to existing optimization methodologies,making it a promising approach for green manufacturing and sustainable supply chain management.展开更多
This paper introduces a groundbreaking metaheuristic algorithm named Magnificent Frigatebird Optimization(MFO),inspired by the unique behaviors observed in magnificent frigatebirds in their natural habitats.The founda...This paper introduces a groundbreaking metaheuristic algorithm named Magnificent Frigatebird Optimization(MFO),inspired by the unique behaviors observed in magnificent frigatebirds in their natural habitats.The foundation of MFO is based on the kleptoparasitic behavior of these birds,where they steal prey from other seabirds.In this process,a magnificent frigatebird targets a food-carrying seabird,aggressively pecking at it until the seabird drops its prey.The frigatebird then swiftly dives to capture the abandoned prey before it falls into the water.The theoretical framework of MFO is thoroughly detailed and mathematically represented,mimicking the frigatebird’s kleptoparasitic behavior in two distinct phases:exploration and exploitation.During the exploration phase,the algorithm searches for new potential solutions across a broad area,akin to the frigatebird scouting for vulnerable seabirds.In the exploitation phase,the algorithm fine-tunes the solutions,similar to the frigatebird focusing on a single target to secure its meal.To evaluate MFO’s performance,the algorithm is tested on twenty-three standard benchmark functions,including unimodal,high-dimensional multimodal,and fixed-dimensional multimodal types.The results from these evaluations highlight MFO’s proficiency in balancing exploration and exploitation throughout the optimization process.Comparative studies with twelve well-known metaheuristic algo-rithms demonstrate that MFO consistently achieves superior optimization results,outperforming its competitors across various metrics.In addition,the implementation of MFO on four engineering design problems shows the effectiveness of the proposed approach in handling real-world applications,thereby validating its practical utility and robustness.展开更多
Objective:To conduct changes in sexual activity during pregnancy and its related factors in pregnant women.Methods:The present descriptive cross-sectional study was conducted in 2017 on pregnant women who referred to ...Objective:To conduct changes in sexual activity during pregnancy and its related factors in pregnant women.Methods:The present descriptive cross-sectional study was conducted in 2017 on pregnant women who referred to the women's clinic of Afzalipour Hospital in the southeast of Iran.Participants were included in the study through convenient sampling.The data collection tool was a researcher-made questionnaire consisting of two parts of personal social information of the couple and questions to measure the level of sexual activity and the attitude of the subjects during pregnancy compared to before pregnancy.Results:201 Pregnant women were included.The average age of pregnant women was(27.3±6.1)years and their average gestational age was(24.7±11.8)years.More than 62%of women had decreased sexual activity.There was a significant relationship between the amount of changes in sexual activity and delivery time(P=0.013),abortion history(P=0.001)and premature birth history(P=0.002).Most pregnant women believed that sex during pregnancy caused damage to the fetus(67.7%).A decrease in the intensity of sexual desire was reported in 63%of pregnant women.More than 60%of the subjects did not consult with doctors and midwives with regards to sexual issues(63.5%).The most common reason for not consulting was not feeling the need(32%).Most women experienced back pain during(42.8%)and after(39.8%)intercourse.Conclusions:Changes in sex life during pregnancy are often caused by the lack of sexual knowledge and the increase in misconceptions among couples,which can affect the quality of relationships.The role of education is essential.Therefore,it is suggested that by including sexual counseling along with pregnancy care,wrong beliefs and information among women will be corrected.展开更多
AIM： To determine the causative agents of spontaneous bacterial peritonitis （SBP） in children with liver disease and ascites in our center. METHODS： During a 2.5 year period, from September 2003 to March 2006, 12 ...AIM： To determine the causative agents of spontaneous bacterial peritonitis （SBP） in children with liver disease and ascites in our center. METHODS： During a 2.5 year period, from September 2003 to March 2006, 12 patients with 13 episodes of SBP were studied. In all cases at the time of admission serum albumin and glucose, urinalysis and urine culture was performed. Analysis [white blood cell （WBC） count with differential, albumin, glucose], gram stain, culture by BACTEC method and antibiogram was done on ascitic fluids. Abdominal paracentesis was repeated after 48 h of antibiotic therapy for bacteriologic assay. The patients were followed for at least three months in a gastroenterology clinic. RESULTS： There were 7 girls （58%） and 5 boys （42%） with a median age of 5.2 years （range, 6 mo to 16 years）. All cases had positive ascitic fluid culture. Gram stain was positive in 5 （38.5%） of them. The isolated organisms were S. pneumoniae in 5 （38.5%）, E. coli in 2 （15.3%）, S. viridans in 2 （15.3%）, and K. pneumoniae, H. influenza, Enterococci, and nontypable Streptococcus each in one （7.7%）. All of them except Enterococci were sensitive to ciprofloxacin and ceftriaxone. All ascitic fluid cultures were negative after 48 h of antibiotic therapy. CONCLUSION： S. pneumoniae is the most common cause of SBP in the pediatric age group and we recommend a third generation cephalosporine （e.g., Ceftriaxlone or Cefotaxime） for empirical therapy in children with SBP.展开更多
In this article,a novel metaheuristic technique named Far and Near Optimization(FNO)is introduced,offeringversatile applications across various scientific domains for optimization tasks.The core concept behind FNO lie...In this article,a novel metaheuristic technique named Far and Near Optimization(FNO)is introduced,offeringversatile applications across various scientific domains for optimization tasks.The core concept behind FNO lies inintegrating global and local search methodologies to update the algorithm population within the problem-solvingspace based on moving each member to the farthest and nearest member to itself.The paper delineates the theoryof FNO,presenting a mathematical model in two phases:(i)exploration based on the simulation of the movementof a population member towards the farthest member from itself and(ii)exploitation based on simulating themovement of a population member towards the nearest member from itself.FNO’s efficacy in tackling optimizationchallenges is assessed through its handling of the CEC 2017 test suite across problem dimensions of 10,30,50,and 100,as well as to address CEC 2020.The optimization results underscore FNO’s adeptness in exploration,exploitation,and maintaining a balance between them throughout the search process to yield viable solutions.Comparative analysis against twelve established metaheuristic algorithms reveals FNO’s superior performance.Simulation findings indicate FNO’s outperformance of competitor algorithms,securing the top rank as the mosteffective optimizer across a majority of benchmark functions.Moreover,the outcomes derived by employing FNOon twenty-two constrained optimization challenges from the CEC 2011 test suite,alongside four engineering designdilemmas,showcase the effectiveness of the suggested method in tackling real-world scenarios.展开更多
BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal polyps.AIM To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Poly...BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal polyps.AIM To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also investigated.METHODS AI4CRP was developed in-house and CAD EYE was proprietary software provided by Fujifilm.Both CADxsystems exploit convolutional neural networks.Colorectal polyps were characterized as benign or premalignant and histopathology was used as gold standard.AI4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values<0.6 indicating benign and values≥0.6 indicating premalignant colorectal polyps.Low confidence characterizations were defined as values 40%around the cut-off value of 0.6(<0.36 and>0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence characterizations.RESULTS AI4CRP use was feasible and performed on 30 patients with 51 colorectal polyps.Self-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to AI4CRP.CAD EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%specificity.Diagnostic performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed best.CONCLUSION Real-time use of AI4CRP was feasible.Objective confidence values provided by a CADx is novel and self-critical AI4CRP showed higher diagnostic performances compared 展开更多
To maximize conversion efficiency,photovoltaic(PV)systems generally operate in the maximum power point tracking(MPPT)mode.However,due to the increasing penetra tion level of PV systems,there is a need for more develop...To maximize conversion efficiency,photovoltaic(PV)systems generally operate in the maximum power point tracking(MPPT)mode.However,due to the increasing penetra tion level of PV systems,there is a need for more developed control functions in terms of frequency support services and voltage control to maintain the reliability and stability of the power grid.Therefore,flexible active power control is a manda tory task for grid-connected PV systems to meet part of the grid requirements.Hence,a significant number of flexible pow er point tracking(FPPT)algorithms have been introduced in the existing literature.The purpose of such algorithms is to real ize a cost-effective method to provide grid support functional ities while minimizing the reliance on energy storage systems.This paper provides a comprehensive overview of grid support functionalities that can be obtained with the FPPT control of PV systems such as frequency support and volt-var control.Each of these grid support functionalities necessitates PV sys tems to operate under one of the three control strategies,which can be provided with FPPT algorithms.The three control strate gies are classified as:①constant power generation control(CP GC),②power reserve control(PRC),and③power ramp rate control(PRRC).A detailed discussion on available FPPT algo rithms for each control strategy is also provided.This paper can serve as a comprehensive review of the state-of-the-art FPPT algorithms that can equip PV systems with various grid support functionalities.展开更多
This paper introduces the Wolverine Optimization Algorithm(WoOA),a biomimetic method inspired by the foraging behaviors of wolverines in their natural habitats.WoOA innovatively integrates two primary strategies:scave...This paper introduces the Wolverine Optimization Algorithm(WoOA),a biomimetic method inspired by the foraging behaviors of wolverines in their natural habitats.WoOA innovatively integrates two primary strategies:scavenging and hunting,mirroring the wolverine’s adeptness in locating carrion and pursuing live prey.The algorithm’s uniqueness lies in its faithful simulation of these dual strategies,which are mathematically structured to optimize various types of problems effectively.The effectiveness of WoOA is rigorously evaluated using the Congress on Evolutionary Computation(CEC)2017 test suite across dimensions of 10,30,50,and 100.The results showcase WoOA’s robust performance in exploration,exploitation,and maintaining a balance between these phases throughout the search process.Compared to twelve established metaheuristic algorithms,WoOA consistently demonstrates a superior performance across diverse benchmark functions.Statistical analyses,including paired t-tests,Friedman test,and Wilcoxon rank-sum tests,validate WoOA’s significant competitive edge over its counterparts.Additionally,WoOA’s practical applicability is illustrated through its successful resolution of twenty-two constrained scenarios from the CEC 2011 suite and four complex engineering design challenges.These applications underscore WoOA’s efficacy in tackling real-world optimization challenges,further highlighting its potential for widespread adoption in engineering and scientific domains.展开更多
This study was conducted to generate genetic information in rice varieties based on a complete diallel crosses over two years. The results indicated that genotype effect was significant for all traits. Genotype ×...This study was conducted to generate genetic information in rice varieties based on a complete diallel crosses over two years. The results indicated that genotype effect was significant for all traits. Genotype × environment interaction effects were significant only for cooked grain length （CGL） and cooked grain shape （CGSH）. General combining ability （GCA） and specific combining ability （SCA） effects were significant for entire traits, which indicated the important roles of both additive and non-additive gene actions. GCA x environment interaction effects were significant for CGL, CGSH and grain elongation index （GEI）. In the controlling of the inheritance of milled grain shape （GSH）, milled grain width （MGW）, GEI, milled grain length （MGL）, CGSH and cooked grain width （CGW）, the additive gene effects were more important than non-additive one. The average degree of dominance was within the range of partial dominance for all of the traits. The narrow-sense heritability was ranged from 0.65 （GSH） to 0.36 （CGL）. GCA effects were significant for all of the parents in milled grain length and it was significant for some of the parents in other traits. The crosses of Deilmani × IRFAON-215 exhibited significant SCA for GEI. The positive mean of heterosis was observed for CGW. The highest maximum values of heterosis were revealed in GEI, flowed by GSH, MGW and CGW. GCA and MPV were significantly and positively correlated together for all traits.展开更多
Solitary rectal ulcer syndrome(SRUS) is a benign and chronic disorder well known in young adults and less in children.It is often related to prolonged excessive straining or abnormal defecation and clinically presents...Solitary rectal ulcer syndrome(SRUS) is a benign and chronic disorder well known in young adults and less in children.It is often related to prolonged excessive straining or abnormal defecation and clinically presents as rectal bleeding,copious mucus discharge,feeling of incomplete defecation,and rarely rectal prolapse.SRUS is diagnosed based on clinical symptoms and endoscopic and histological findings.The current treatments are suboptimal,and despite correct diagnosis,outcomes can be unsatisfactory.Some treatment protocols for SRUS include conservative management such as family reassurance,regulation of toilet habits,avoidance of straining,encouragement of a high-fiber diet,topical treatments with salicylate,sulfasalazine,steroids and sucralfate,and surgery.In children,SRUS is relatively uncommon but troublesome and easily misdiagnosed with other common diseases,however,it is being reported more than in the past.This condition in children is benign;however,morbidity is an important problem as reflected by persistence of symptoms,especially rectal bleeding.In this review,we discuss current diagnosis and treatment for SRUS.展开更多
Objective:To investigate the epidemiological pattern of animal bites in Yazd Province,central Iran.Methods:In this cross-sectional study,8 545 individuals with animal bites who were referred to the Yazd Province Rabie...Objective:To investigate the epidemiological pattern of animal bites in Yazd Province,central Iran.Methods:In this cross-sectional study,8 545 individuals with animal bites who were referred to the Yazd Province Rabies Treatment Center were investigated using the census method from April 2013 to March 2017.The variables included:demographic information,household living condition,the type of biting animals,the domesticated and wild animals,the time of biting based on year,the residence location (urban or rural),and the treatment status.Data were analyzed by descriptive statistics using Excel 2013,SPSS version 25 and Arc GIS 14.1 Software.Results:A total of 8 545 cases of animal bites were reported in Yazd province from 2013 to 2017.The most animal bites (with 4 253 case of bites) and the lowest animal bites (with 121 case of bites) occurred in Yazd and Bahabad district,respectively.The incidence of animal bites was 168.4 per 100 000 people during the five-year period.Most of cases (73.9%) occurred in urban areas.Dog and cat bites accounted for 47.6% and 47.4% of all cases,respectively.Most of animal bites were reported in the summer (29.4%).Sixty percent of the cases received incomplete treatments,while 40% of them received complete treatments.During this study,three positive cases of fatal rabies from dog bites were reported.Conclusions:The incidence of animal bites is high in Yazd province,and more patients are bitten by dog and cat.Hence,educational,preventive,and informative programs are required to reduce the incidence of animal bites.展开更多
文摘AIM: To evaluate different methods in differentiating idiopathic neonatal hepatitis from biliary atresia. METHODS: Sixty-five infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis and biliary atresia were studied prospectively from September 2003 to March 2006. A thorough history and physical examination were undertaken and the liver enzymes were examined. All cases underwent abdominal ultrasonography, hepatobiliary scintigraphy, and percutaneous liver biopsy. The accuracy, sensitivity, specificity and predictive values of these various methods were compared. RESULTS: There were 34 girls and 31 boys, among them 46 subjects had idiopathic neonatal hepatitis (age, 61 ± 17 d) and 19 had biliary atresia (age, 64 ± 18 d). The mean age at onset of jaundice was significantly lower in cases of biliary atresia when compared to idiopathic neonatal hepatitis cases (9 ± 13 d vs 20 ± 21 d; P = 0.032). The diagnostic accuracy of different methods was as follows: liver biopsy, 96.9%; clinical evaluation, 70.8%; ultrasonography, 69.2%; hepatobiliary scintigraphy, 58.5%; and liver enzymes, 50.8%.CONCLUSION: Our results indicate that clinical evaluation by an experienced pediatric hepatologist and a biopsy of the liver are considered as the most reliable methods to differentiate idiopathic neonatal hepatitis and biliary atresia.
文摘Carbon quantum dots （CQDs） have emerged as potential alternatives to classical metal-based semiconductor quantum dots （QDs） due to the abundance of their precursors, their ease of synthesis, high biocompatibility, low cost, and particularly their strong photoresponsiveness, tunability, and stability. Light is a versatile, tunable stimulus that can provide spatiotemporal control. Its interaction with CQDs elicits interesting responses such as wavelength-dependent optical emissions, charge/electron transfer, and heat generation, processes that are suitable for a range of photomediated bioapplications. The carbogenic core and surface characteristics of CQDs can be tuned through versatile engineering strategies to endow specific optical and physicochemical properties, while conjugation with specific moieties can enable the design of targeted probes. Fundamental approaches to tune the responses of CQDs to photo-interactions and the design of bionanoprobes are presented, which enable biomedical applications involving diagnostics and therapeutics. These strategies represent comprehensive platforms for engineering multifunctional probes for nanomedicine, and the design of QD probes with a range of metal-free and emer^in~ 2D materials.
文摘AIM： To evaluate the clinical presentation, response to prophylactic therapy and outcome of children with cyclic vomiting syndrome （CVS） in Shiraz, Iran. METHODS： During a period of 11 years （March 1994 to March 2005）, 181 consecutive children with a final diagnosis of CVS were evaluated, treated and followed in our center. Patients were randomized to receive either amitriptyline or propranolol as prophylactic treatments. RESULTS： There were 88 boys and 93 girls with mean age of onset of symptoms of 4.9 ± 3.3 years （range, neonatal period to 14 years）, the mean age at final diagnosis was 6.9 years （range, 1.5 to 14）, and the mean duration between the onset of the first attack and the final diagnosis of CVS was 2 ± 1.81 years （range, 1/6 to 8）. The mean duration of each attack was 4.26 days （range, from few hours to 10 d） and the mean interval between the attacks was 1.8 mo （range, 1 wk to 12 too）. The time of onset of the attacks was midnight to early morning in about 70% of cases. Amitriptyline was effective in 46 out of 81 （56%） patients （P 〈 0.001）. Propranolol appeared to have a superior action and was effective in 74 out of 83 （92%） patients （P 〈 0.0001）. CONCLUSION： There is a significant lag time between the onset of clinical symptoms and the final diagnosis of CVS in our area. In patients with typical clinical presentations of CVS, who are examined by an experienced physician, invasive workup is not necessary. Propranolol appears more effective than arnitriptyline for prophylactic use in children with CVS.
文摘Surface roughness and shape play an important role on the behavior of particles in various processes such as flotation. In this re- search, the influence of different grinding methods on the surface roughness and shape characteristics of quartz particles as well as the effect of these parameters on the flotation of the particles was investigated. The surface roughness of the particles was determined by measuring their specific surface area via the gas adsorption method. The shape characteristics of the particles were measured and calculated by images obtained by scanning electron microscopy via an image analysis system. The flotation kinetics was determined using a laboratory flotation cell. The results showed that the particles of rod mill products have higher roughness and elongation ratio and lower roundness than the parti- cles of ball mill products. The flotation kinetics constant of the particles increased with their surface roughness increasing. Particles with higher elongation and lower roundness indicated higher floatability. In addition, the influence of the surface roughness on the flotation kinet- ics was greater than that of shape parameters.
文摘Due to nonlinear behavior of power production of photovoltaic(PV)systems,it is necessary to apply the maximum power point tracking(MPPT)techniques to generate the maximum power.The conventional MPPT methods do not function properly in rapidly changing atmospheric conditions.In this study,a fuzzy logic controller(FLC)optimized by a combination of particle swarm optimization(PSO)and genetic algorithm(GA)is proposed to obtain the maximum power point(MPP).The proposed FLC uses the ratio of power variations to voltage variations and the derivative of power variations to voltage variations as inputs and uses the duty cycle as the output.The range of changes in fuzzy membership functions and fuzzy rules are proposed as an optimization problem optimized by the PSO-GA.The proposed design is validated for MPPT of a PV system using MATLAB/Simulink software.The results indicate a better performance of the proposed FLC compared to the common methods.
文摘This research presents a novel nature-inspired metaheuristic algorithm called Frilled Lizard Optimization(FLO),which emulates the unique hunting behavior of frilled lizards in their natural habitat.FLO draws its inspiration from the sit-and-wait hunting strategy of these lizards.The algorithm’s core principles are meticulously detailed and mathematically structured into two distinct phases:(i)an exploration phase,which mimics the lizard’s sudden attack on its prey,and(ii)an exploitation phase,which simulates the lizard’s retreat to the treetops after feeding.To assess FLO’s efficacy in addressing optimization problems,its performance is rigorously tested on fifty-two standard benchmark functions.These functions include unimodal,high-dimensional multimodal,and fixed-dimensional multimodal functions,as well as the challenging CEC 2017 test suite.FLO’s performance is benchmarked against twelve established metaheuristic algorithms,providing a comprehensive comparative analysis.The simulation results demonstrate that FLO excels in both exploration and exploitation,effectively balancing these two critical aspects throughout the search process.This balanced approach enables FLO to outperform several competing algorithms in numerous test cases.Additionally,FLO is applied to twenty-two constrained optimization problems from the CEC 2011 test suite and four complex engineering design problems,further validating its robustness and versatility in solving real-world optimization challenges.Overall,the study highlights FLO’s superior performance and its potential as a powerful tool for tackling a wide range of optimization problems.
文摘The presence of Hg in the aqueous media is known to cause severe health issues in both humans and animals.Many technologies and especially adsorbents have been applied for its removal. In this study, a graphene oxide–carbon composite(GO–CC) as a new adsorbent was prepared by sol gel procedure and characterized using field emission scanning electron microscopy, BET and EDX. The effects of different variables including solution p H, contact time, adsorbent dose and GO ratio in adsorbent matrix on the removal capacity of Hg were studied. The isotherm data correlated well with the Langmuir isotherm model. Further analysis recommended that the Hg^(2+) adsorption process is governed by the intra-particle and external mass transfer, in which the film diffusion was the rate restrictive step. The presented composite has maximum absorption capacity, q_(max) of 68.8 mg·g^(-1), which is comparable with carbon based adsorbent reported in the previous publications.
基金financially supported by Research Deputy,Shahid Sadoughi University of Medical Sciences,Yazd,Iran,with project No.P/17/1/19412
文摘Objective: To investigate and predict the effects of climate change on the potential distribution of the main vector and reservoir hosts of the disease in Yazd province in the future.Methods: Distribution data for vector and reservoir hosts of zoonotic cutaneous leishmaniasis in Yazd province were obtained from earlier studies conducted in the area.MaxEnt ecological niche modeling was used to predict environmental suitability.BCC-CSM1-1(m) model and two climate change scenarios, RCP 4.5 and RCP 8.5 were used for horizons 2030 and 2050 climate projections.Future projections were based on data of a regional climate change model.Results: With both scenarios in 2030 and 2050, the results of jackknife test indicated that the mean temperature of wettest quarter and temperature annual range had the greatest effect on the model for the vector and the reservoir hosts, respectively.Conclusions: The climate conditions are the major determinants of zoonotic cutaneous leishmaniasis incidence rate in Yazd Province.These climate conditions provide favorable habitats for ease transmission of zoonotic cutaneous leishmaniasis in this endemic area.Habitats suitability for the vector and reservoir will be expanding in the coming years compared with the current conditions, such that, in horizon 2030 & 2050, the probability of the presence of the vector and reservoir within 38 580 and 37 949 km^2, respectively, from Yazd province is above 60%.Moreover, an increase is predicted in the presence of the vector in the western parts and the reservoir in the northern and central parts of the province in the future.Understanding the role of environmental and bioclimatic factors in zoonotic cutaneous leishmaniasis occurrence can provide a guide for policy-makers in the creation and implementation of more effective policies for prevention and control.
文摘Pulmonary fibrosis, a chronic inflammatory disease that occurs mainly in older adults, is a serious health threat with few effective treatment options. The etiological aspects of pulmonary fibrosis remain unknown, though some factors such as cigarette smoking, viral infections, surfactant protein polymorphisms, and chronic or high doses use of certain drugs are considered to be risk factors for the progression of pulmonary fibrosis. No standard treatments have been introduced in clinic yet. Although glucocorticoids and antioxidant drugs have been administered, the severe and broad-spectrum adverse effects of glucocorticoids limit their use. Efforts to identify novel therapeutic agents with improved safety profiles are therefore ongoing. In this review, the authors have described the effects of herbal extracts and compounds and certain pharmacological agents on pulmonary fibrosis in animal models. These effects indicate that herbs are a promising source of compounds that can play pivotal roles in the treatment of lung fibrosis.
基金This research is funded by the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan,Grant No.AP19674517.
文摘The efficiency of businesses is often hindered by the challenges encountered in traditional Supply Chain Manage-ment(SCM),which is characterized by elevated risks due to inadequate accountability and transparency.To address these challenges and improve operations in green manufacturing,optimization algorithms play a crucial role in supporting decision-making processes.In this study,we propose a solution to the green lot size optimization issue by leveraging bio-inspired algorithms,notably the Stork Optimization Algorithm(SOA).The SOA draws inspiration from the hunting and winter migration strategies employed by storks in nature.The theoretical framework of SOA is elaborated and mathematically modeled through two distinct phases:exploration,based on migration simulation,and exploitation,based on hunting strategy simulation.To tackle the green lot size optimization issue,our methodology involved gathering real-world data,which was then transformed into a simplified function with multiple constraints aimed at optimizing total costs and minimizing CO_(2) emissions.This function served as input for the SOA model.Subsequently,the SOA model was applied to identify the optimal lot size that strikes a balance between cost-effectiveness and sustainability.Through extensive experimentation,we compared the performance of SOA with twelve established metaheuristic algorithms,consistently demonstrating that SOA outperformed the others.This study’s contribution lies in providing an effective solution to the sustainable lot-size optimization dilemma,thereby reducing environmental impact and enhancing supply chain efficiency.The simulation findings underscore that SOA consistently achieves superior outcomes compared to existing optimization methodologies,making it a promising approach for green manufacturing and sustainable supply chain management.
基金This research is funded by the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan(Grant No.AP19674517).
文摘This paper introduces a groundbreaking metaheuristic algorithm named Magnificent Frigatebird Optimization(MFO),inspired by the unique behaviors observed in magnificent frigatebirds in their natural habitats.The foundation of MFO is based on the kleptoparasitic behavior of these birds,where they steal prey from other seabirds.In this process,a magnificent frigatebird targets a food-carrying seabird,aggressively pecking at it until the seabird drops its prey.The frigatebird then swiftly dives to capture the abandoned prey before it falls into the water.The theoretical framework of MFO is thoroughly detailed and mathematically represented,mimicking the frigatebird’s kleptoparasitic behavior in two distinct phases:exploration and exploitation.During the exploration phase,the algorithm searches for new potential solutions across a broad area,akin to the frigatebird scouting for vulnerable seabirds.In the exploitation phase,the algorithm fine-tunes the solutions,similar to the frigatebird focusing on a single target to secure its meal.To evaluate MFO’s performance,the algorithm is tested on twenty-three standard benchmark functions,including unimodal,high-dimensional multimodal,and fixed-dimensional multimodal types.The results from these evaluations highlight MFO’s proficiency in balancing exploration and exploitation throughout the optimization process.Comparative studies with twelve well-known metaheuristic algo-rithms demonstrate that MFO consistently achieves superior optimization results,outperforming its competitors across various metrics.In addition,the implementation of MFO on four engineering design problems shows the effectiveness of the proposed approach in handling real-world applications,thereby validating its practical utility and robustness.
文摘Objective:To conduct changes in sexual activity during pregnancy and its related factors in pregnant women.Methods:The present descriptive cross-sectional study was conducted in 2017 on pregnant women who referred to the women's clinic of Afzalipour Hospital in the southeast of Iran.Participants were included in the study through convenient sampling.The data collection tool was a researcher-made questionnaire consisting of two parts of personal social information of the couple and questions to measure the level of sexual activity and the attitude of the subjects during pregnancy compared to before pregnancy.Results:201 Pregnant women were included.The average age of pregnant women was(27.3±6.1)years and their average gestational age was(24.7±11.8)years.More than 62%of women had decreased sexual activity.There was a significant relationship between the amount of changes in sexual activity and delivery time(P=0.013),abortion history(P=0.001)and premature birth history(P=0.002).Most pregnant women believed that sex during pregnancy caused damage to the fetus(67.7%).A decrease in the intensity of sexual desire was reported in 63%of pregnant women.More than 60%of the subjects did not consult with doctors and midwives with regards to sexual issues(63.5%).The most common reason for not consulting was not feeling the need(32%).Most women experienced back pain during(42.8%)and after(39.8%)intercourse.Conclusions:Changes in sex life during pregnancy are often caused by the lack of sexual knowledge and the increase in misconceptions among couples,which can affect the quality of relationships.The role of education is essential.Therefore,it is suggested that by including sexual counseling along with pregnancy care,wrong beliefs and information among women will be corrected.
文摘AIM： To determine the causative agents of spontaneous bacterial peritonitis （SBP） in children with liver disease and ascites in our center. METHODS： During a 2.5 year period, from September 2003 to March 2006, 12 patients with 13 episodes of SBP were studied. In all cases at the time of admission serum albumin and glucose, urinalysis and urine culture was performed. Analysis [white blood cell （WBC） count with differential, albumin, glucose], gram stain, culture by BACTEC method and antibiogram was done on ascitic fluids. Abdominal paracentesis was repeated after 48 h of antibiotic therapy for bacteriologic assay. The patients were followed for at least three months in a gastroenterology clinic. RESULTS： There were 7 girls （58%） and 5 boys （42%） with a median age of 5.2 years （range, 6 mo to 16 years）. All cases had positive ascitic fluid culture. Gram stain was positive in 5 （38.5%） of them. The isolated organisms were S. pneumoniae in 5 （38.5%）, E. coli in 2 （15.3%）, S. viridans in 2 （15.3%）, and K. pneumoniae, H. influenza, Enterococci, and nontypable Streptococcus each in one （7.7%）. All of them except Enterococci were sensitive to ciprofloxacin and ceftriaxone. All ascitic fluid cultures were negative after 48 h of antibiotic therapy. CONCLUSION： S. pneumoniae is the most common cause of SBP in the pediatric age group and we recommend a third generation cephalosporine （e.g., Ceftriaxlone or Cefotaxime） for empirical therapy in children with SBP.
文摘In this article,a novel metaheuristic technique named Far and Near Optimization(FNO)is introduced,offeringversatile applications across various scientific domains for optimization tasks.The core concept behind FNO lies inintegrating global and local search methodologies to update the algorithm population within the problem-solvingspace based on moving each member to the farthest and nearest member to itself.The paper delineates the theoryof FNO,presenting a mathematical model in two phases:(i)exploration based on the simulation of the movementof a population member towards the farthest member from itself and(ii)exploitation based on simulating themovement of a population member towards the nearest member from itself.FNO’s efficacy in tackling optimizationchallenges is assessed through its handling of the CEC 2017 test suite across problem dimensions of 10,30,50,and 100,as well as to address CEC 2020.The optimization results underscore FNO’s adeptness in exploration,exploitation,and maintaining a balance between them throughout the search process to yield viable solutions.Comparative analysis against twelve established metaheuristic algorithms reveals FNO’s superior performance.Simulation findings indicate FNO’s outperformance of competitor algorithms,securing the top rank as the mosteffective optimizer across a majority of benchmark functions.Moreover,the outcomes derived by employing FNOon twenty-two constrained optimization challenges from the CEC 2011 test suite,alongside four engineering designdilemmas,showcase the effectiveness of the suggested method in tackling real-world scenarios.
文摘BACKGROUND Artificial intelligence(AI)has potential in the optical diagnosis of colorectal polyps.AIM To evaluate the feasibility of the real-time use of the computer-aided diagnosis system(CADx)AI for ColoRectal Polyps(AI4CRP)for the optical diagnosis of diminutive colorectal polyps and to compare the performance with CAD EYE^(TM)(Fujifilm,Tokyo,Japan).CADx influence on the optical diagnosis of an expert endoscopist was also investigated.METHODS AI4CRP was developed in-house and CAD EYE was proprietary software provided by Fujifilm.Both CADxsystems exploit convolutional neural networks.Colorectal polyps were characterized as benign or premalignant and histopathology was used as gold standard.AI4CRP provided an objective assessment of its characterization by presenting a calibrated confidence characterization value(range 0.0-1.0).A predefined cut-off value of 0.6 was set with values<0.6 indicating benign and values≥0.6 indicating premalignant colorectal polyps.Low confidence characterizations were defined as values 40%around the cut-off value of 0.6(<0.36 and>0.76).Self-critical AI4CRP’s diagnostic performances excluded low confidence characterizations.RESULTS AI4CRP use was feasible and performed on 30 patients with 51 colorectal polyps.Self-critical AI4CRP,excluding 14 low confidence characterizations[27.5%(14/51)],had a diagnostic accuracy of 89.2%,sensitivity of 89.7%,and specificity of 87.5%,which was higher compared to AI4CRP.CAD EYE had a 83.7%diagnostic accuracy,74.2%sensitivity,and 100.0%specificity.Diagnostic performances of the endoscopist alone(before AI)increased nonsignificantly after reviewing the CADx characterizations of both AI4CRP and CAD EYE(AI-assisted endoscopist).Diagnostic performances of the AI-assisted endoscopist were higher compared to both CADx-systems,except for specificity for which CAD EYE performed best.CONCLUSION Real-time use of AI4CRP was feasible.Objective confidence values provided by a CADx is novel and self-critical AI4CRP showed higher diagnostic performances compared
基金supported in part by the Future Battery Industries Cooperative Research Center(www.fbicrc.com.au)as part of the Australian Government’s CRC Program(www.business.gov.au),which supports industry-led collaborations between industry,researchers and the community.
文摘To maximize conversion efficiency,photovoltaic(PV)systems generally operate in the maximum power point tracking(MPPT)mode.However,due to the increasing penetra tion level of PV systems,there is a need for more developed control functions in terms of frequency support services and voltage control to maintain the reliability and stability of the power grid.Therefore,flexible active power control is a manda tory task for grid-connected PV systems to meet part of the grid requirements.Hence,a significant number of flexible pow er point tracking(FPPT)algorithms have been introduced in the existing literature.The purpose of such algorithms is to real ize a cost-effective method to provide grid support functional ities while minimizing the reliance on energy storage systems.This paper provides a comprehensive overview of grid support functionalities that can be obtained with the FPPT control of PV systems such as frequency support and volt-var control.Each of these grid support functionalities necessitates PV sys tems to operate under one of the three control strategies,which can be provided with FPPT algorithms.The three control strate gies are classified as:①constant power generation control(CP GC),②power reserve control(PRC),and③power ramp rate control(PRRC).A detailed discussion on available FPPT algo rithms for each control strategy is also provided.This paper can serve as a comprehensive review of the state-of-the-art FPPT algorithms that can equip PV systems with various grid support functionalities.
文摘This paper introduces the Wolverine Optimization Algorithm(WoOA),a biomimetic method inspired by the foraging behaviors of wolverines in their natural habitats.WoOA innovatively integrates two primary strategies:scavenging and hunting,mirroring the wolverine’s adeptness in locating carrion and pursuing live prey.The algorithm’s uniqueness lies in its faithful simulation of these dual strategies,which are mathematically structured to optimize various types of problems effectively.The effectiveness of WoOA is rigorously evaluated using the Congress on Evolutionary Computation(CEC)2017 test suite across dimensions of 10,30,50,and 100.The results showcase WoOA’s robust performance in exploration,exploitation,and maintaining a balance between these phases throughout the search process.Compared to twelve established metaheuristic algorithms,WoOA consistently demonstrates a superior performance across diverse benchmark functions.Statistical analyses,including paired t-tests,Friedman test,and Wilcoxon rank-sum tests,validate WoOA’s significant competitive edge over its counterparts.Additionally,WoOA’s practical applicability is illustrated through its successful resolution of twenty-two constrained scenarios from the CEC 2011 suite and four complex engineering design challenges.These applications underscore WoOA’s efficacy in tackling real-world optimization challenges,further highlighting its potential for widespread adoption in engineering and scientific domains.
基金The projcct was carried out in the farm and laboratory of Rice Research Institute of Iran(RRII)in Rasht
文摘This study was conducted to generate genetic information in rice varieties based on a complete diallel crosses over two years. The results indicated that genotype effect was significant for all traits. Genotype × environment interaction effects were significant only for cooked grain length （CGL） and cooked grain shape （CGSH）. General combining ability （GCA） and specific combining ability （SCA） effects were significant for entire traits, which indicated the important roles of both additive and non-additive gene actions. GCA x environment interaction effects were significant for CGL, CGSH and grain elongation index （GEI）. In the controlling of the inheritance of milled grain shape （GSH）, milled grain width （MGW）, GEI, milled grain length （MGL）, CGSH and cooked grain width （CGW）, the additive gene effects were more important than non-additive one. The average degree of dominance was within the range of partial dominance for all of the traits. The narrow-sense heritability was ranged from 0.65 （GSH） to 0.36 （CGL）. GCA effects were significant for all of the parents in milled grain length and it was significant for some of the parents in other traits. The crosses of Deilmani × IRFAON-215 exhibited significant SCA for GEI. The positive mean of heterosis was observed for CGW. The highest maximum values of heterosis were revealed in GEI, flowed by GSH, MGW and CGW. GCA and MPV were significantly and positively correlated together for all traits.
文摘Solitary rectal ulcer syndrome(SRUS) is a benign and chronic disorder well known in young adults and less in children.It is often related to prolonged excessive straining or abnormal defecation and clinically presents as rectal bleeding,copious mucus discharge,feeling of incomplete defecation,and rarely rectal prolapse.SRUS is diagnosed based on clinical symptoms and endoscopic and histological findings.The current treatments are suboptimal,and despite correct diagnosis,outcomes can be unsatisfactory.Some treatment protocols for SRUS include conservative management such as family reassurance,regulation of toilet habits,avoidance of straining,encouragement of a high-fiber diet,topical treatments with salicylate,sulfasalazine,steroids and sucralfate,and surgery.In children,SRUS is relatively uncommon but troublesome and easily misdiagnosed with other common diseases,however,it is being reported more than in the past.This condition in children is benign;however,morbidity is an important problem as reflected by persistence of symptoms,especially rectal bleeding.In this review,we discuss current diagnosis and treatment for SRUS.
文摘Objective:To investigate the epidemiological pattern of animal bites in Yazd Province,central Iran.Methods:In this cross-sectional study,8 545 individuals with animal bites who were referred to the Yazd Province Rabies Treatment Center were investigated using the census method from April 2013 to March 2017.The variables included:demographic information,household living condition,the type of biting animals,the domesticated and wild animals,the time of biting based on year,the residence location (urban or rural),and the treatment status.Data were analyzed by descriptive statistics using Excel 2013,SPSS version 25 and Arc GIS 14.1 Software.Results:A total of 8 545 cases of animal bites were reported in Yazd province from 2013 to 2017.The most animal bites (with 4 253 case of bites) and the lowest animal bites (with 121 case of bites) occurred in Yazd and Bahabad district,respectively.The incidence of animal bites was 168.4 per 100 000 people during the five-year period.Most of cases (73.9%) occurred in urban areas.Dog and cat bites accounted for 47.6% and 47.4% of all cases,respectively.Most of animal bites were reported in the summer (29.4%).Sixty percent of the cases received incomplete treatments,while 40% of them received complete treatments.During this study,three positive cases of fatal rabies from dog bites were reported.Conclusions:The incidence of animal bites is high in Yazd province,and more patients are bitten by dog and cat.Hence,educational,preventive,and informative programs are required to reduce the incidence of animal bites.
