目的:考察室温条件下注射用泮托唑钠与8种临床常用药物的配伍稳定性。方法:建立了泮托拉唑钠高效液相含量测定方法,模拟临床应用,以0.9%的氯化钠溶液为溶媒,按比例分别将注射用泮托拉唑钠与肌苷注射液、维生素B6注射液、维生素K_1注射...目的:考察室温条件下注射用泮托唑钠与8种临床常用药物的配伍稳定性。方法:建立了泮托拉唑钠高效液相含量测定方法,模拟临床应用,以0.9%的氯化钠溶液为溶媒,按比例分别将注射用泮托拉唑钠与肌苷注射液、维生素B6注射液、维生素K_1注射液、注射用辅酶A、氨苯甲酸注射液、酚磺乙胺注射液、门冬氨酸钾镁注射液、注射用ATP8种临床常见药物混合,在混合后即刻、0.5,1,2 h 4个时间点考察泮托拉唑含量、外观、不溶性微粒、溶液pH值的变化。结果:泮托拉唑钠与氨苯甲酸、酚磺乙胺、维生素B6配伍后2 h内含量明显下降。结论:泮托拉唑对pH敏感,注射用泮托拉唑钠不宜与氨苯甲酸、酚磺乙胺、维生素B6配伍,序贯使用时需冲洗管路。展开更多
In this paper, we explore the linear combinations of right half-plane mappings and vertical strip mappings. We demonstrate that the combinations of these harmonic mappings are convex in the vertical direction provided...In this paper, we explore the linear combinations of right half-plane mappings and vertical strip mappings. We demonstrate that the combinations of these harmonic mappings are convex in the vertical direction provided they are locally univalent and sense-preserving. Furthermore, we extend this analysis to a more general case by setting specific conditions. Additionally, we take some common parameters such as as the dilatation of these harmonic mappings, and prove the sufficient conditions that their combinations are locally univalent and convex in the vertical direction. Several examples are constructed by the Mathematica software to demonstrate our main results.展开更多
基金supported by the STI2030-Major Projects(2021ZD0203100)the National Natural Science Foundation of China(31922030,32171010,31771170,31900720,and 32171009)+3 种基金the Guangdong Basic and Applied Basic Research Foundation(2023B1515040010,2021B1515020035,2019A1515011598,and 2023A1515010478)the Science and Technology Program of Guangdong(2018B030334001)the Science and Technology Program of Guangzhou(202007030012)the Programme of Introducing Talents of Discipline to Universities(B14036).
文摘目的:考察室温条件下注射用泮托唑钠与8种临床常用药物的配伍稳定性。方法:建立了泮托拉唑钠高效液相含量测定方法,模拟临床应用,以0.9%的氯化钠溶液为溶媒,按比例分别将注射用泮托拉唑钠与肌苷注射液、维生素B6注射液、维生素K_1注射液、注射用辅酶A、氨苯甲酸注射液、酚磺乙胺注射液、门冬氨酸钾镁注射液、注射用ATP8种临床常见药物混合,在混合后即刻、0.5,1,2 h 4个时间点考察泮托拉唑含量、外观、不溶性微粒、溶液pH值的变化。结果:泮托拉唑钠与氨苯甲酸、酚磺乙胺、维生素B6配伍后2 h内含量明显下降。结论:泮托拉唑对pH敏感,注射用泮托拉唑钠不宜与氨苯甲酸、酚磺乙胺、维生素B6配伍,序贯使用时需冲洗管路。
文摘In this paper, we explore the linear combinations of right half-plane mappings and vertical strip mappings. We demonstrate that the combinations of these harmonic mappings are convex in the vertical direction provided they are locally univalent and sense-preserving. Furthermore, we extend this analysis to a more general case by setting specific conditions. Additionally, we take some common parameters such as as the dilatation of these harmonic mappings, and prove the sufficient conditions that their combinations are locally univalent and convex in the vertical direction. Several examples are constructed by the Mathematica software to demonstrate our main results.