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Study on Influence Factors of Pressure Injury Risk in the Elderly Inpatients with Kidney Disease Based on LASSO Regression 被引量:4
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作者 Ling Liu Chunhua Wang +5 位作者 lianghong yin Jiayi Wang Hong Yang yingxue Zhong Zhiwei Mou Yu Chen 《Open Journal of Preventive Medicine》 2020年第6期95-107,共13页
<strong>Objective</strong>: This paper aims to explore clinical status and related influence factors of pressure injury (PI) in the elderly inpatients with kidney disease, so as to provide reference for th... <strong>Objective</strong>: This paper aims to explore clinical status and related influence factors of pressure injury (PI) in the elderly inpatients with kidney disease, so as to provide reference for the prevention and treatment of PI in the elderly inpatients with kidney disease. <strong>Methods</strong>: Retrospective collection method is adopted to collect 158 clinical cases of the elderly inpatients with kidney disease aged ≥ 60 in the Nephrology Department, the First Affiliated Hospital of Jinan University from January 2017 to December 2019, and then least absolute shrinkage and selection Operator (LASSO) regression analysis is used to analyze 17 possible influence factors;finally Logistic regression model is established to analyze and screen influence factors of risk. <strong>Results</strong>: 1) Among 158 elderly inpatients with medium and high risk of PI, the incidence of PI is 20.25%;the most common stage of injury is stage I (42.5%);sacrococcygeal (60%) is the high-risk site of pressure injury. 2) LASSO regression analysis shows that history of present respiratory infection/respiratory failure (<em>β </em>= 1.2714. <em>P</em> < 0.05) and hospitalization time (<em>β</em> = 0.4177. <em>P </em>< 0.05) are independent factors influencing PI risk in the elderly inpatients with kidney disease. <strong>Concl</strong><strong>usio</strong><strong>n</strong>: The elderly patients with kidney disease and PI risk are the high incidence population of hospital acquired PI;for the elderly inpatients with kidney disease and having respiratory infection history or respiratory failure, prolonged hospitalization will significantly increase the risk of PI. Therefore, targeted preventive and control measures should be taken to reduce the incidence of PI. 展开更多
关键词 Least Absolute Shrinkage and Selection Operator The Elderly Inpatients with Kidney Disease Pressure Injury Influence Factors NURSING
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The Medical Care of Multiple Disciplinary Team Reduces the Risks of Complications in Patients after Arteriovenous Fistula Operation
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作者 Hong Yang Zhihua Deng +3 位作者 yingxue Zhong lianghong yin Fanna Liu Yu Chen 《Open Journal of Nephrology》 2020年第2期117-124,共8页
Introduction: Arteriovenous fistula (AVF) operation is recognized a gold standard of hemodialysis for end-stage renal disease. Because various complications may occur during perioperative period, medical care plays an... Introduction: Arteriovenous fistula (AVF) operation is recognized a gold standard of hemodialysis for end-stage renal disease. Because various complications may occur during perioperative period, medical care plays an important role in improving the possibility of AVF operation. The objective of the study was to explore the effect of the mode of multiple disciplinary team (MDT) medical care on the patients with end-stage renal disease treated by arteriovenous fistula (AVF) operation. Method: 98 patients with end-stage renal disease under the AVF operation were divided into observation group and control group. The control group was performed with regular medical care and for the observation group was treated under the mode of MDT medical care. Complications after operation, hospitalized time and medical satisfaction were comprehensively compared between the both groups. Results: The overall complications including swelling, bleeding, infection and thrombosis in observation group accounted for 5%, however, 19% of patients suffered different complications in the control group. The total complications significantly decreased in the observation group compared with control group (P < 0.001). The hospitalization time was shortened to 9.8 ± 5.6 days in the observation group, and the average hospitalization in control group was 17.8 ± 8.9 days. The medical satisfaction was increased by 20.83 percent in the observation group compared with the control group (P < 0.001). 75% patients in control group were satisfied with medical care, and 98.53% patients were satisfied for observation group. Conclusion: The mode of MDT medical care was beneficial for patients with end-stage renal disease after AVF operation, which could significantly reduce complications, hospitalized time and improve patients’ degree of satisfaction. Thus, it should be recommended in the clinical work. 展开更多
关键词 Multiple Disciplinary Team Medical Care HEMODIALYSIS Arteriovenous Fistula
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藤仓赤霉菌赤霉素生物合成及代谢调控研究进展 被引量:4
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作者 王冰璇 司文 +5 位作者 吴烨飞 张心齐 汪石莹 吴酬飞 林海萍 尹良鸿 《生物工程学报》 CAS CSCD 北大核心 2020年第2期189-200,共12页
赤霉素是最重要的植物生长调节剂之一,在农业生产中得到越来越广泛的应用,具有广阔的市场前景,但其工业化的高生产成本严重制约着它的广泛应用。近年来,利用生物技术提升赤霉素产量日益成为研究热点。赤霉素生物合成是多种酶协同作用的... 赤霉素是最重要的植物生长调节剂之一,在农业生产中得到越来越广泛的应用,具有广阔的市场前景,但其工业化的高生产成本严重制约着它的广泛应用。近年来,利用生物技术提升赤霉素产量日益成为研究热点。赤霉素生物合成是多种酶协同作用的过程,阐明赤霉素的生物合成机制,利用代谢工程策略调控代谢流量,对提高赤霉素产量至关重要。文中综述了当前藤仓赤霉菌赤霉素生物合成途径、关键酶、环境因素、代谢流调控等方面的研究进展,在代谢调控方面进行了展望,以期为实现赤霉素稳产高产提供思路。 展开更多
关键词 藤仓赤霉菌 赤霉素 生物合成 代谢调控 关键酶
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