The conjugation of external species with twodimensional(2D)materials has broad application prospects.In this study,we have explored the potential of noble metal/2D MOF heterostructures in hydrogen storage.Specifically...The conjugation of external species with twodimensional(2D)materials has broad application prospects.In this study,we have explored the potential of noble metal/2D MOF heterostructures in hydrogen storage.Specifically,the MgH_(2)-Ni-MOF@Pd system has shown remarkable hydrogen desorption/sorption performances,starting to liberate hydrogen at 1810C,which is 2300C lower than that of pristine MgH2.Under the catalytic effect of Ni-MOF@Pd,the dehydrogenation apparent activation energy of MgH2 is noticeably decreased from(133.5±17.5)to(34.58±1.87)kJ·moL^(-1),and the hydrogenation apparent activation energy is reduced from(70.41±7.43)to(25.78±4.64)kJ·moL^(-1),which is lowered by 63.4%.The fully-dehydrogenated MgH2-NiMOF@Pd composite rapidly uptakes hydrogen,with 2.62wt%at 100℃and 6.06 wt%at 150℃within 300 s,respectively.The mechanism analysis of MgH2 catalyzed by Ni-MOF@Pd has revealed that the transformation of Mg_2Ni and Mg_2NiH_4 could act as a"hydrogen pump",providing numerous channels for fast diffusion and transport of hydrogen atoms.Moreover,in the dehydrogenation process,the element Pd reacts with MgH_(2)to form the MgPd alloy phase,which makes MgH_(2)take precedence to decompose through the Mg-Pd alloy rather than self-decomposition,further reducing thermal stability and improving de/hydrogenation kinetics.The synergistic effect of Mg-Pd,Mg_2Ni,and the special ultra-thin 2D sheet structure of the additive is the main reason for the good hydrogen storage property of MgH_(2)-Ni-MOF@Pd.Our findings provide inspiration for designing efficient multifunctional additives with unique morphologies to optimize the hydrogen desorption/sorption behaviors of hydrogen storage materials.展开更多
[目的]原油储罐目前普遍趋向于大型化、集中化。由于原油理化性质与储罐材料构件的复杂性,造成储罐的高风险性,需提高储罐罐区风险管理能力。应用现有主流的基于风险的检验技术(Risk Based Inspection,RBI)对储罐风险进行评价较为复杂,...[目的]原油储罐目前普遍趋向于大型化、集中化。由于原油理化性质与储罐材料构件的复杂性,造成储罐的高风险性,需提高储罐罐区风险管理能力。应用现有主流的基于风险的检验技术(Risk Based Inspection,RBI)对储罐风险进行评价较为复杂,其对于现场数据要求较多,且设备因素评价中缺少针对储罐相关附件的影响分析。[方法]提出一种原油储罐分级预警体系,通过建立基于逼近理想解排序方法(Technique for Order Preference by Similarity to an Ideal Solution,TOPSIS)的储罐风险分级预警体系模型,实现对储罐风险的综合评估与分级预警:①建立储罐风险评估指标体系,包括人、设备、环境及管理因素4个一级指标以及若干二级、三级指标;②应用层次分析法(Analytic Hierarchy Process,AHP)对不同层次指标进行赋权,并利用TOPSIS方法对储罐进行相对贴近度计算;③根据相对贴近度结果对储罐进行风险排序与分级预警。[结果]以中国西部某原油储备库区4个原油储罐为研究对象进行风险分级预警,TOPSIS评估结果与API581-2016《基于风险的检验》、EEMUA159-2017《地上平底储罐:检查维护和修理指南》两种标准的风险评估结果基本一致,可有效预警,且实施便捷、评价指标更为全面。[结论]研究成果能够为罐区巡检、安排储罐大修周期提供合理参考。(图2,表8,参20)展开更多
Two new compounds, namely taenialactam C and globorin A（1 and 2）, as well as six known compounds,cornoside（3）, 2-phenylethyl-b-D-glucoside（4）, 3-isopropyl-5-acetoxycyclohexene-2-one-1（5）, 4-methyl-phenol（6）,...Two new compounds, namely taenialactam C and globorin A（1 and 2）, as well as six known compounds,cornoside（3）, 2-phenylethyl-b-D-glucoside（4）, 3-isopropyl-5-acetoxycyclohexene-2-one-1（5）, 4-methyl-phenol（6）, 5-[（2S）-2-aminobutyl]-2-methyl-phenol（7）, and 1-（4-methylphenyl）-1-propanone（8） were isolated from wild Phaeocystis globosa. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds.The structures of the known compounds were identified by comparing their spectroscopic data with those reported in the literature. This paper also reports toxicity properties of the eight compounds against the brine shrimp Artemia salina and juvenile Epinephelus akaara fish. Some of these compounds showed significant lethality on the brine shrimp A. salina and the juvenile E. akaara fish.展开更多
Development of transition metal-based photocatalysts with low cost, strong visible light absorption, and high efficiency is a longstand pursuit for advanced organic synthesis, yet remains highly challenging. In this a...Development of transition metal-based photocatalysts with low cost, strong visible light absorption, and high efficiency is a longstand pursuit for advanced organic synthesis, yet remains highly challenging. In this article, an anthraquinone-based copper(I)cyclic trinuclear complex(1) was designed and it featured strong visible light absorption, high charge separation efficiency and photochemical properties. Complex 1 as a heterogeneous photocatalyst can efficiently catalyze homo-coupling of terminal alkynes and denitrification-oxidative coupling reaction between hydrazinopyridine and terminal alkynes with excellent yield(up to 99%), broad substrate tolerance(27 examples) and superior reusability(up to 10 cycles without loss of performance) under mild conditions.展开更多
Accurate diet identification of top predators is crucial to fully understand their ecological roles.Compared to terrestrial animals,gathering dietary information from cetaceans is notoriously difficult.Here,we applied a...Accurate diet identification of top predators is crucial to fully understand their ecological roles.Compared to terrestrial animals,gathering dietary information from cetaceans is notoriously difficult.Here,we applied a multilocus metabarcoding approach to investigate the diet of vulnerable Indo-Pacific humpback dolphins and Indo-Pacificfinless porpoises from the Pearl River Estuary(PRE),China.Our analyses identified 21 preyfish species from the 42 humpback dolphin stomachs,as well as 10 species offish and 1 species of cephalopod from the 13finless porpoise stomachs.All of the taxa were assigned to the species level,highlighting that the multimarker approach could facilitate species identification.Most of the prey species were small-and medium-sizedfishes that primarily fed on zooplankton.The calculated similarity index revealed a moderated dietary overlap between the 2 cetaceans,presumably due to the feeding of the 2 predators in association withfishing vessels in the PRE.A more diverse diet was observed in humpback dolphins in the closedfishing season compared to thefishing season,implying the influence on the dolphin diet due to the availability of commercialfishery resources.However,according to the results of species rarefaction curves,ourfindings on the feeding habits of the 2 cetaceans are still limited by insufficient sample size and therefore should be interpreted with caution.This study represents afirst attempt to apply the multilocus DNA metabarcoding technique in the diet analysis of small cetaceans,although more efforts are needed to improve this type of analysis.展开更多
We propose a new quantum watermarking scheme based on threshold selection using informational entropy of quantum image.The core idea of this scheme is to embed information into object and background of cover image in ...We propose a new quantum watermarking scheme based on threshold selection using informational entropy of quantum image.The core idea of this scheme is to embed information into object and background of cover image in different ways.First,a threshold method adopting the quantum informational entropy is employed to determine a threshold value.The threshold value can then be further used for segmenting the cover image to a binary image,which is an authentication key for embedding and extraction information.By a careful analysis of the quantum circuits of the scheme,that is,translating into the basic gate sequences which show the low complexity of the scheme.One of the simulation-based experimental results is entropy difference which measures the similarity of two images by calculating the difference in quantum image informational entropy between watermarked image and cover image.Furthermore,the analyses of peak signal-to-noise ratio,histogram and capacity of the scheme are also provided.展开更多
In this paper, we propose a novel quantum secret image-sharing scheme which constructs m quantum secret images into m+1 quantum share images. A chaotic image generated by the logistic map is utilized to assist in the ...In this paper, we propose a novel quantum secret image-sharing scheme which constructs m quantum secret images into m+1 quantum share images. A chaotic image generated by the logistic map is utilized to assist in the construction of quantum share images first. The chaotic image and secret images are expressed as quantum image representation by using the novel enhanced quantum representation. To enhance the confidentiality, quantum secret images are scrambled into disordered images through the Arnold transform. Then the quantum share images are constructed by performing a series of quantum swap operations and quantum controlled-NOT operations. Because all quantum operations are invertible, the original quantum secret images can be reconstructed by performing a series of inverse operations. Theoretical analysis and numerical simulation proved both the security and low computational complexity of the scheme, which has outperformed its classical counterparts. It also provides quantum circuits for sharing and recovery processes.展开更多
Attention-deficit hyperactivity disorder(ADHD) is a neurodevelopmental disorder prevalent in schoolage children. At present, however, its etiologies and risk factors are unknown. Transmembrane α-amino-3-hydroxy-5-met...Attention-deficit hyperactivity disorder(ADHD) is a neurodevelopmental disorder prevalent in schoolage children. At present, however, its etiologies and risk factors are unknown. Transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid(AMPA) receptor regulatory protein γ-8(TARP γ-8,also known as calcium voltage-gated channel auxiliary subunit gamma 8(CACNG8)) is an auxiliary AMPA receptor(AMPAR) subunit. Here, we report an association between TARP γ-8 and ADHD,whereby adolescent TARP γ-8 knockout(KO) mice exhibitedADHD-likebehaviors,including hyperactivity, impulsivity, anxiety, impaired cognition,and memory deficits. Human single-nucleotide polymorphism(SNP) analysis also revealed strong associations between intronic alleles in CACNG8genes and ADHD susceptibility. In addition,synaptosomal proteomic analysis revealed dysfunction of the AMPA glutamate receptor complex in the hippocampi of TARP γ-8 KO mice.Proteomic analysis also revealed dysregulation of dopaminergic and glutamatergic transmissions in the prefrontal cortices of TARP γ-8 KO mice.Methylphenidate(MPH), which is commonly used to treat ADHD, significantly rescued the major behavioral deficits and abnormal synaptosomal proteins in TARP γ-8 KO mice. Notably, MPH significantly reversed the up-regulation of Grik2 and Slc6a3 in the prefrontal cortex. MPH also significantly improved synaptic AMPAR complex function by up-regulating other AMPAR auxiliary proteins in hippocampal synaptosomes. Taken together, our results suggest that TARP γ-8 is involved in the development of ADHD in humans.This study provides a useful alternative animal model with ADHD-like phenotypes related to TARP γ-8deficiency, which has great potential for the development of new therapies.展开更多
1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symp...1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].展开更多
In this paper, by introducing a two-stages polarization mode dispersion (PMD) compensator after a optical fiber link with a large PMD, we compensated over 270ps first-order and 2000ps2 high-order PMD in a optical fibe...In this paper, by introducing a two-stages polarization mode dispersion (PMD) compensator after a optical fiber link with a large PMD, we compensated over 270ps first-order and 2000ps2 high-order PMD in a optical fiber link with super high PMD. Our experimental results shows that, the compensators based on the two-stages of compensator can be used to PMD compensation in a 20Gb/s OTDM system with 60 km high PMD fiber. Before compensation, 270ps DGD is became into max. 7ps after compensation. At simultane...展开更多
Amy Tan's novel The Joy Luck Club describes the complex relation between four Chinese immigrant mothers and their daughters who are raised in America.It reveals different cultural connotation between China and Ame...Amy Tan's novel The Joy Luck Club describes the complex relation between four Chinese immigrant mothers and their daughters who are raised in America.It reveals different cultural connotation between China and America.Misunderstand ing,conflicts,communication and then understanding reflects the process of clash,communication and blending between East and West.In this novel,mother is the medium of national history and memory,the carrier of Chinese culture and the bridge of past and present.On the contrary,daughters are raised in America.They are influenced by American culture.Cultural difference is the main cause of their conflicts.展开更多
基金financially supported by the National Natural Science Foundation of China(Nos.U20A20237,51863005,52271205,51871065,52371218,51863005,52271205,51871065,52371218,51971068,52101245 and 52201206)the Scientific Research and Technology Development Program of Guangxi(Nos.AA19182014,AD17195073,AA17202030-1,AB21220027 and 2021AB17045)+6 种基金the National Natural Science Foundation of Guangxi Province(Nos.2018GXNSFDA281051,2014GXNSFAA118401,2013GXNSFBA019244,2021GXNSFBA075057 and 2022GXNSFB A035632)the Scientific Research and Technology Development Program of Guilin(Nos.20210102-4 and 20210216-1)Guangxi B agui Scholar FoundationGuilin Lijiang Scholar FoundationGuangxi Collaborative Innovation Centre of Structure and Property for New Energy and MaterialsGuangxi Advanced Functional Materials FoundationApplication Talents Small Highlands and Chinesisch Deutsche Kooperationsgruppe(No.GZ1528)。
文摘The conjugation of external species with twodimensional(2D)materials has broad application prospects.In this study,we have explored the potential of noble metal/2D MOF heterostructures in hydrogen storage.Specifically,the MgH_(2)-Ni-MOF@Pd system has shown remarkable hydrogen desorption/sorption performances,starting to liberate hydrogen at 1810C,which is 2300C lower than that of pristine MgH2.Under the catalytic effect of Ni-MOF@Pd,the dehydrogenation apparent activation energy of MgH2 is noticeably decreased from(133.5±17.5)to(34.58±1.87)kJ·moL^(-1),and the hydrogenation apparent activation energy is reduced from(70.41±7.43)to(25.78±4.64)kJ·moL^(-1),which is lowered by 63.4%.The fully-dehydrogenated MgH2-NiMOF@Pd composite rapidly uptakes hydrogen,with 2.62wt%at 100℃and 6.06 wt%at 150℃within 300 s,respectively.The mechanism analysis of MgH2 catalyzed by Ni-MOF@Pd has revealed that the transformation of Mg_2Ni and Mg_2NiH_4 could act as a"hydrogen pump",providing numerous channels for fast diffusion and transport of hydrogen atoms.Moreover,in the dehydrogenation process,the element Pd reacts with MgH_(2)to form the MgPd alloy phase,which makes MgH_(2)take precedence to decompose through the Mg-Pd alloy rather than self-decomposition,further reducing thermal stability and improving de/hydrogenation kinetics.The synergistic effect of Mg-Pd,Mg_2Ni,and the special ultra-thin 2D sheet structure of the additive is the main reason for the good hydrogen storage property of MgH_(2)-Ni-MOF@Pd.Our findings provide inspiration for designing efficient multifunctional additives with unique morphologies to optimize the hydrogen desorption/sorption behaviors of hydrogen storage materials.
文摘[目的]原油储罐目前普遍趋向于大型化、集中化。由于原油理化性质与储罐材料构件的复杂性,造成储罐的高风险性,需提高储罐罐区风险管理能力。应用现有主流的基于风险的检验技术(Risk Based Inspection,RBI)对储罐风险进行评价较为复杂,其对于现场数据要求较多,且设备因素评价中缺少针对储罐相关附件的影响分析。[方法]提出一种原油储罐分级预警体系,通过建立基于逼近理想解排序方法(Technique for Order Preference by Similarity to an Ideal Solution,TOPSIS)的储罐风险分级预警体系模型,实现对储罐风险的综合评估与分级预警:①建立储罐风险评估指标体系,包括人、设备、环境及管理因素4个一级指标以及若干二级、三级指标;②应用层次分析法(Analytic Hierarchy Process,AHP)对不同层次指标进行赋权,并利用TOPSIS方法对储罐进行相对贴近度计算;③根据相对贴近度结果对储罐进行风险排序与分级预警。[结果]以中国西部某原油储备库区4个原油储罐为研究对象进行风险分级预警,TOPSIS评估结果与API581-2016《基于风险的检验》、EEMUA159-2017《地上平底储罐:检查维护和修理指南》两种标准的风险评估结果基本一致,可有效预警,且实施便捷、评价指标更为全面。[结论]研究成果能够为罐区巡检、安排储罐大修周期提供合理参考。(图2,表8,参20)
基金supported by grants from National Natural Science Foundation of China (No. 31100260, 81260480, and 41566004)National Natural Science Foundation of Guangxi (No. 2011GXNSFE018002)+1 种基金Guangxi Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences (No. GXKLHY13-06)Foundation of Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences (No. 201210ZS)
文摘Two new compounds, namely taenialactam C and globorin A（1 and 2）, as well as six known compounds,cornoside（3）, 2-phenylethyl-b-D-glucoside（4）, 3-isopropyl-5-acetoxycyclohexene-2-one-1（5）, 4-methyl-phenol（6）, 5-[（2S）-2-aminobutyl]-2-methyl-phenol（7）, and 1-（4-methylphenyl）-1-propanone（8） were isolated from wild Phaeocystis globosa. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds.The structures of the known compounds were identified by comparing their spectroscopic data with those reported in the literature. This paper also reports toxicity properties of the eight compounds against the brine shrimp Artemia salina and juvenile Epinephelus akaara fish. Some of these compounds showed significant lethality on the brine shrimp A. salina and the juvenile E. akaara fish.
基金Guo-Hong Ning is thankful for the support from the Guangdong Basic and Applied Basic Research Foundation (2019B151502024)the Guangzhou Science and Technology Project (202201020038)+1 种基金supported by the National Natural Science Foundation of China (22371091, 21975104, 22150004, 22101099)the Guangdong Major Project of Basic and Applied Research (2019B030302009)。
文摘Development of transition metal-based photocatalysts with low cost, strong visible light absorption, and high efficiency is a longstand pursuit for advanced organic synthesis, yet remains highly challenging. In this article, an anthraquinone-based copper(I)cyclic trinuclear complex(1) was designed and it featured strong visible light absorption, high charge separation efficiency and photochemical properties. Complex 1 as a heterogeneous photocatalyst can efficiently catalyze homo-coupling of terminal alkynes and denitrification-oxidative coupling reaction between hydrazinopyridine and terminal alkynes with excellent yield(up to 99%), broad substrate tolerance(27 examples) and superior reusability(up to 10 cycles without loss of performance) under mild conditions.
基金supported by the Natural Science Foundation of Guangdong Province(2017A030308005)in Chinathe National Natural Science Foundation of China(41576128,42007225)+4 种基金Guangdong Basic and Applied Basic Research Foundation(2020A1515010910)in ChinaChina Postdoctoral Science Foundation(2019M653153)Fundamental Research Funds for the Central Universities(19lgpy95)Ocean Park Conservation Foundation of Hong Kong(MM01.1718)Innovation Group Project of Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)(311021004,311020003).
文摘Accurate diet identification of top predators is crucial to fully understand their ecological roles.Compared to terrestrial animals,gathering dietary information from cetaceans is notoriously difficult.Here,we applied a multilocus metabarcoding approach to investigate the diet of vulnerable Indo-Pacific humpback dolphins and Indo-Pacificfinless porpoises from the Pearl River Estuary(PRE),China.Our analyses identified 21 preyfish species from the 42 humpback dolphin stomachs,as well as 10 species offish and 1 species of cephalopod from the 13finless porpoise stomachs.All of the taxa were assigned to the species level,highlighting that the multimarker approach could facilitate species identification.Most of the prey species were small-and medium-sizedfishes that primarily fed on zooplankton.The calculated similarity index revealed a moderated dietary overlap between the 2 cetaceans,presumably due to the feeding of the 2 predators in association withfishing vessels in the PRE.A more diverse diet was observed in humpback dolphins in the closedfishing season compared to thefishing season,implying the influence on the dolphin diet due to the availability of commercialfishery resources.However,according to the results of species rarefaction curves,ourfindings on the feeding habits of the 2 cetaceans are still limited by insufficient sample size and therefore should be interpreted with caution.This study represents afirst attempt to apply the multilocus DNA metabarcoding technique in the diet analysis of small cetaceans,although more efforts are needed to improve this type of analysis.
基金supported by the National Natural Science Foundation of China(Grant No.6217070290)the Shanghai Science and Technology Project(Grant Nos.21JC1402800 and 20040501500)+2 种基金the Scientific Research Fund of Hunan Provincial Education Department(Grant No.21A0470)the Hunan Provincial Natural Science Foundation of China(Grant No.2020JJ4557)Top-Notch Innovative Talent Program for Postgraduate Students of Shanghai Maritime University(Grant No.2021YBR009)。
文摘We propose a new quantum watermarking scheme based on threshold selection using informational entropy of quantum image.The core idea of this scheme is to embed information into object and background of cover image in different ways.First,a threshold method adopting the quantum informational entropy is employed to determine a threshold value.The threshold value can then be further used for segmenting the cover image to a binary image,which is an authentication key for embedding and extraction information.By a careful analysis of the quantum circuits of the scheme,that is,translating into the basic gate sequences which show the low complexity of the scheme.One of the simulation-based experimental results is entropy difference which measures the similarity of two images by calculating the difference in quantum image informational entropy between watermarked image and cover image.Furthermore,the analyses of peak signal-to-noise ratio,histogram and capacity of the scheme are also provided.
基金Project supported by the National Key Research and Development Plan(Grant Nos.2018YFC1200200 and 2018YFC1200205)the National Natural Science Foundation of China(Grant No.61463016)the "Science and Technology Innovation Action Plan" of Shanghai in 2017(Grant No.17510740300)
文摘In this paper, we propose a novel quantum secret image-sharing scheme which constructs m quantum secret images into m+1 quantum share images. A chaotic image generated by the logistic map is utilized to assist in the construction of quantum share images first. The chaotic image and secret images are expressed as quantum image representation by using the novel enhanced quantum representation. To enhance the confidentiality, quantum secret images are scrambled into disordered images through the Arnold transform. Then the quantum share images are constructed by performing a series of quantum swap operations and quantum controlled-NOT operations. Because all quantum operations are invertible, the original quantum secret images can be reconstructed by performing a series of inverse operations. Theoretical analysis and numerical simulation proved both the security and low computational complexity of the scheme, which has outperformed its classical counterparts. It also provides quantum circuits for sharing and recovery processes.
基金supported by the National Natural Science Foundation of China (81872848, 81803509)National Major Special Project on New Drug Innovation grant(2018ZX09711001-004-003)+3 种基金CAMS Innovation Fund for Medical Sciences (2019-I2M-5-055)Hebei Natural Science Foundation(H2019206038)National Key R&D Program of China(2019YFA0801603)Natural Science Foundation of Jiangsu Province (BE2019707)。
文摘Attention-deficit hyperactivity disorder(ADHD) is a neurodevelopmental disorder prevalent in schoolage children. At present, however, its etiologies and risk factors are unknown. Transmembrane α-amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid(AMPA) receptor regulatory protein γ-8(TARP γ-8,also known as calcium voltage-gated channel auxiliary subunit gamma 8(CACNG8)) is an auxiliary AMPA receptor(AMPAR) subunit. Here, we report an association between TARP γ-8 and ADHD,whereby adolescent TARP γ-8 knockout(KO) mice exhibitedADHD-likebehaviors,including hyperactivity, impulsivity, anxiety, impaired cognition,and memory deficits. Human single-nucleotide polymorphism(SNP) analysis also revealed strong associations between intronic alleles in CACNG8genes and ADHD susceptibility. In addition,synaptosomal proteomic analysis revealed dysfunction of the AMPA glutamate receptor complex in the hippocampi of TARP γ-8 KO mice.Proteomic analysis also revealed dysregulation of dopaminergic and glutamatergic transmissions in the prefrontal cortices of TARP γ-8 KO mice.Methylphenidate(MPH), which is commonly used to treat ADHD, significantly rescued the major behavioral deficits and abnormal synaptosomal proteins in TARP γ-8 KO mice. Notably, MPH significantly reversed the up-regulation of Grik2 and Slc6a3 in the prefrontal cortex. MPH also significantly improved synaptic AMPAR complex function by up-regulating other AMPAR auxiliary proteins in hippocampal synaptosomes. Taken together, our results suggest that TARP γ-8 is involved in the development of ADHD in humans.This study provides a useful alternative animal model with ADHD-like phenotypes related to TARP γ-8deficiency, which has great potential for the development of new therapies.
基金Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2019-I2M-5-023)Hainan Provincial Science and Technology Major Project(No.ZDKJ201804)+2 种基金National Natural Science Foundation of China(No.81871611)National Natural Science Foundation of China(No.81760352)Project of Hainan Provincial Department of Education(No.Hnjg2019ZD-16)
文摘1.Introduction Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac causes.It is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].
基金Supported by National Science Foundations of ChinaNational 863 High Technology Projects of China.
文摘In this paper, by introducing a two-stages polarization mode dispersion (PMD) compensator after a optical fiber link with a large PMD, we compensated over 270ps first-order and 2000ps2 high-order PMD in a optical fiber link with super high PMD. Our experimental results shows that, the compensators based on the two-stages of compensator can be used to PMD compensation in a 20Gb/s OTDM system with 60 km high PMD fiber. Before compensation, 270ps DGD is became into max. 7ps after compensation. At simultane...
文摘Amy Tan's novel The Joy Luck Club describes the complex relation between four Chinese immigrant mothers and their daughters who are raised in America.It reveals different cultural connotation between China and America.Misunderstand ing,conflicts,communication and then understanding reflects the process of clash,communication and blending between East and West.In this novel,mother is the medium of national history and memory,the carrier of Chinese culture and the bridge of past and present.On the contrary,daughters are raised in America.They are influenced by American culture.Cultural difference is the main cause of their conflicts.
