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18% Efficiency organic solar cells 被引量:85
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作者 Qishi Liu Yufan Jiang +10 位作者 Ke Jin Jianqiang qin Jingui Xu Wenting Li Ji Xiong Jinfeng Liu Zuo Xiao kuan Sun Shangfeng Yang Xiaotao Zhang Liming Ding 《Science Bulletin》 SCIE EI CAS CSCD 2020年第4期272-275,共4页
In 1995,Yu et al.[1]first reported bulk-heterojunction(BHJ)solar cells with a conjugated polymer donor and a fullerene acceptor as the active materials.From then on,BHJ organic solar cells(OSCs)have attracted academic... In 1995,Yu et al.[1]first reported bulk-heterojunction(BHJ)solar cells with a conjugated polymer donor and a fullerene acceptor as the active materials.From then on,BHJ organic solar cells(OSCs)have attracted academic and industrial interests due to the advantages like lightweight,flexibility and roll-to-roll fabrication.Nowadays,17%power conversion efficiencies(PCEs)have been achieved in the state-of-the-art OSCs[2,3].The remarkable progress in OSCs relies on the continuously emerging new materials and device fabrication technologies,and the understanding on film morphology and device physics[4,5]. 展开更多
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A 2.16 eV bandgap polymer donor gives 16%power conversion efficiency 被引量:14
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作者 Tan Wang Jianqiang qin +9 位作者 Zuo Xiao Xianyi Meng Chuantian Zuo Bin Yang Hairen Tan Junliang Yang Shangfeng Yang kuan Sun Suyuan Xie Liming Ding 《Science Bulletin》 SCIE EI CAS CSCD 2020年第3期179-181,共3页
Nowadays,wide-bandgap(WBG)copolymers attract great attention in the field of organic photovoltaics[1].They are ideal electron-donating partners for low-bandgap small molecule acceptors[2-12].With good energy levels ma... Nowadays,wide-bandgap(WBG)copolymers attract great attention in the field of organic photovoltaics[1].They are ideal electron-donating partners for low-bandgap small molecule acceptors[2-12].With good energy levels matching,the blend of WBG copolymer donor and small molecule acceptor can harvest most of the sunlight and deliver high power conversion efficiencies(PCEs)in solar cells.PCEs higher than 16%have been achieved[13-15].WBG copolymers especially those with ultra-wide bandgaps(i.e.,optical bandgap(Eg opt)>2.07 eV,absorption onset<600 nm)can find applications in ternary solar cells[16]and tandem solar cells[17].Currently,ultra-WBG copolymer donors are less efficient,generally giving PCEs below 13%[18].Designing highly efficient ultra-WBG copolymers is needed.In this work,we use fluorine-and alkoxyl-substituted benzene(FAB)as the building block to construct ultra-WBG copolymer donors. 展开更多
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2018年夏季某石化工业区VOCs浓度特征及活性物种 被引量:13
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作者 张博韬 景宽 +2 位作者 王琴 安欣欣 刘保献 《环境科学研究》 EI CAS CSCD 北大核心 2021年第6期1318-1327,共10页
为明确某石化工业区VOCs浓度特征及活性物种,利用法国Chromatotec公司生产的airmo VOC expert C_(2)-C_(6)和airmo VOC expert C_(6)-C_(12)分析仪联用系统在2018年夏季对该工业区VOCs进行连续监测.结果表明:①研究期间,石化工业区φ(TV... 为明确某石化工业区VOCs浓度特征及活性物种,利用法国Chromatotec公司生产的airmo VOC expert C_(2)-C_(6)和airmo VOC expert C_(6)-C_(12)分析仪联用系统在2018年夏季对该工业区VOCs进行连续监测.结果表明:①研究期间,石化工业区φ(TVOCs)(57种VOCs物种体积分数之和)为93.7×10^(-9)±87.5×10^(-9),其中烯烃占比最高,达44.9%,当φ(TVOCs)日均值越高时烯烃占比越高.体积分数较高的物种主要为低碳烯烃、低碳烷烃、正己烷、甲苯和苯.②石化工业区φ(TVOCs)呈显著的夜高昼低变化特征,且各组分变化趋势相近,其中烯烃变幅高于其他组分.③各排放物质中对O_(3)生成贡献较大的主要是乙烯、丙烯、顺-2-丁烯、甲苯等物质,而对二次有机气溶胶生成贡献较大的主要是甲苯、异丙苯、间对二甲苯等物质.④通过PMF解析发现,石化工业区内催化裂化及裂解、催化重整及废水废液处理、油储设施溢散的贡献率分别为51.7%、34.8%、13.5%.⑤降低石化工业区VOCs活性可以明显降低O_(3)超标率,若同时降低VOCs活性与φ(NO_(x))可更有效地降低O_(3)超标率.研究显示,石化工业区VOCs排放强度较大,应对催化裂化及裂解等重点排放单元,以及乙烯、丙烯和甲苯等活性物质的排放进行控制,降低VOCs整体活性,并协同控制区域内NO_(x)排放,从而减少O_(3)污染. 展开更多
关键词 挥发性有机物(VOCs) 石化工业区 浓度特征 活性物种
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北京市黑碳气溶胶浓度特征及其主要影响因素 被引量:11
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作者 曹阳 安欣欣 +3 位作者 刘保献 景宽 王琴 罗霄旭 《环境科学》 EI CAS CSCD 北大核心 2021年第12期5633-5643,共11页
为探究北京市黑碳(black carbon,BC)气溶胶时空分布特征及其主要影响因素,对4个站点2019年的ρ(BC)、ρ(PM_(2.5))、ρ(CO)和φ(NO_(x))及同期气象因子进行比对分析.结果表明,背景区(BA)、城区(UA)、城区路边(UR)和外环路边(HR)的平均ρ... 为探究北京市黑碳(black carbon,BC)气溶胶时空分布特征及其主要影响因素,对4个站点2019年的ρ(BC)、ρ(PM_(2.5))、ρ(CO)和φ(NO_(x))及同期气象因子进行比对分析.结果表明,背景区(BA)、城区(UA)、城区路边(UR)和外环路边(HR)的平均ρ(BC)分别为(1.58±1.15)、(2.27±1.67)、(3.35±2.13)和(3.57±2.40)μg·m^(-3),ω(BC/PM_(2.5))分别为(5.3±1.6)%、(6.0±2.3)%、(9.0±3.6)%和(8.1±3.5)%;除UR站点ρ(CO)高于HR站点以外,4个站点的ρ(BC)、ρ(PM_(2.5))、ρ(CO)和φ(NO_(x))由低到高排序均为:背景区<城区<城区路边<外环路边,且采暖季是非采暖季的1.1~1.7倍;用最大频率法估算各站本底ρ(BC),UR站点最高,BA站点最低,分别为0.56μg·m^(-3)和0.19μg·m^(-3);交通排放导致路边站点本底ρ(BC)、平均ρ(BC)和ω(BC/PM_(2.5))均高于其他站点.ρ(BC)日变化曲线呈双峰型结构,非采暖季早高峰时段(07:00~08:00)峰值较高,采暖季全天浓度高于非采暖季且凌晨时段(00:00~02:00)峰值较高,谷值均在午后(14:00~16:00)出现.4个站点的平均吸收埃斯特朗指数(AAE)为1.38、1.34、1.26和1.26,表明全市BC主要来自化石燃料燃烧;采暖季平均AAE为1.46,高于非采暖季的1.23,主要是由于采暖季生物质燃烧排放占比增加;非采暖季各站点AAE日变化曲线主要受机动车活动时间影响,一致呈凌晨低、午后高的分布特点,采暖季曲线各异.BC与PM_(2.5)、CO、NO_(x)、风速和相对湿度的Pearson相关系数(r)为0.86、0.81、0.69、-0.37和0.34;由于燃煤源作为4种污染物的共同来源贡献增加,采暖季较非采暖季|r|更高.4个站点的ΔBC/ΔCO值分别为3.1×10^(-3)、3.5×10^(-3)、3.9×10^(-3)和4.1×10^(-3).一次污染过程中,城区站点BC以区域传输为主要来源,路边站点局地排放BC积累过程较明显,易发生颗粒物二次生成过程。 展开更多
关键词 黑碳(BC) 路边站 浓度特征 日变化 吸收埃斯特朗指数(AAE) 污染过程
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Effects of Water-Collecting and -Retaining Techniques on Photosynthetic Rates, Yield, and Water Use Efficiency of Millet Grown in a Semiarid Region 被引量:10
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作者 WEN Xiao-xia ZHANG De-qi +2 位作者 LIAO Yun-cheng JIA Zhi-kuan JI Shu-qin 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2012年第7期1119-1128,共10页
Field experiments were conducted in 2003 and 2004 to study the effects of plastic ridges and furrow film mulching (plastic film on sowing, as well as plastic film on flat soil and hole sowing) and chemicals (a drou... Field experiments were conducted in 2003 and 2004 to study the effects of plastic ridges and furrow film mulching (plastic film on sowing, as well as plastic film on flat soil and hole sowing) and chemicals (a drought resistant agent and a water- retaining agent) on growth, photosynthetic rate, yield, and water use efficiency (WUE) of spring millet (Setaria italica L.). The experimental results showed that water-collecting and -retaining techniques can effectively increase soil moisture content, the leaf photosynthetic rate and crop growth. Due to increased soil moisture under the plastic-covered ridge and furrow water-collecting in July and August, dry matter and plant height had a increase at the booting stage (late growth advantage). However, the plastic-covered flat soil and hole sowing reduced soil evaporation during early growth, the increase of dry matter and plant height appeared at the seedling stage (early growth advantage). Plastic-covered ridge and furrow sowing supplemented with chemical reagents had significant positive effects on water collection and soil moisture retention. Improvement of soil moisture resulted into the increase of the photosynthetic rate, dry matter accumulation yield and WUE. The water-collecting and -retaining techniques can improve WUE and enhance crop yield. Correlation analysis demonstrated that the photosynthetic rate under the water-collecting and -retaining techniques was significantly associated with the soil moisture, but had no significant relationship with leaf chlorophyll content. Plastic- covered ridge and furrow sowing supplemented with chemical reagents increased the yield and WUE by 114% and 8.16 kg ha-1 mm-1, respectively, compared with the control; while without the chemical reagents the yield and WUE were 95% and 7.42 kg ha-1 mm-1 higher, respectively, than those of the control. 展开更多
关键词 water use efficiency Loess Plateau of China plastic film mulch drought-resistant agent water-retaining agent
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基于不同超声成像的甲状腺结节良恶性判别 被引量:10
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作者 武宽 秦品乐 +1 位作者 柴锐 曾建朝 《计算机应用》 CSCD 北大核心 2020年第1期77-82,共6页
为实现更为准确的甲状腺结节良恶性超声图像诊断,避免不必要的穿刺或活检手术,提出了一种基于卷积神经网络(CNN)的常规超声成像和超声弹性成像的特征结合方法,提高了甲状腺结节良恶性分类准确率。首先,卷积网络模型在大规模自然图像数... 为实现更为准确的甲状腺结节良恶性超声图像诊断,避免不必要的穿刺或活检手术,提出了一种基于卷积神经网络(CNN)的常规超声成像和超声弹性成像的特征结合方法,提高了甲状腺结节良恶性分类准确率。首先,卷积网络模型在大规模自然图像数据集上完成预训练,并通过迁移学习的方式将特征参数迁移到超声图像域用以生成深度特征并处理小样本。然后,结合常规超声成像和超声弹性成像的深度特征图形成混合特征空间。最后,在混合特征空间上完成分类任务,实现了一个端到端的卷积网络模型。在1 156幅图像上进行实验,所提方法的准确率为0.924,高于其他单一数据源的方法。实验结果表明,浅层卷积共享图像的边缘纹理特征,高层卷积的抽象特征与具体的分类任务相关,使用迁移学习的方法可以解决数据样本不足的问题;同时,弹性超声影像可以对甲状腺结节的病灶硬度进行客观的量化,结合常规超声的纹理轮廓特征,二者融合的混合特征可以更全面地描述不同病灶之间的差异。所提方法可以高效准确地对甲状腺结节进行良恶性分类,减轻患者痛苦,给医生提供更为准确的辅助诊断信息。 展开更多
关键词 图像分类 迁移学习 特征融合 深度学习 超声影像 弹性超声
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青海省不同地区燕麦田杂草组成及群落特征 被引量:10
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作者 柴继宽 慕平 +3 位作者 赵桂琴 曾亮 贾志锋 苟智强 《草地学报》 CAS CSCD 北大核心 2018年第2期306-311,共6页
为明确青海省不同地区燕麦田杂草的组成和群落结构,采用倒置"W"取样法对青海省不同地区燕麦田杂草进行了调查和物种多样性分析。结果表明,青海省燕麦田常见杂草有25种,隶属17科23属,其中以菊科、蓼科、十字花科和苋科为主,优... 为明确青海省不同地区燕麦田杂草的组成和群落结构,采用倒置"W"取样法对青海省不同地区燕麦田杂草进行了调查和物种多样性分析。结果表明,青海省燕麦田常见杂草有25种,隶属17科23属,其中以菊科、蓼科、十字花科和苋科为主,优势杂草有5种,分别是野胡萝卜、香薷、节裂角茴香、灰绿藜、猪殃殃。从杂草的分布区域来看,青海省4个区域中,平安区燕麦田杂草群落的物种丰富度最高,有21种杂草,而湟中县的Simpson优势度指数最高。经聚类分析,青海省4个区域燕麦田杂草群落可以分为3组,互助县和平安县杂草群落聚为一组,湟中县和海晏县燕麦田杂草群落结构各有特点,分别单独成一组。 展开更多
关键词 燕麦田 杂草群落 群落多样性 聚类分析
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维生素D参与隔药灸对溃疡性结肠炎大鼠结肠的影响研究 被引量:9
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作者 王宽 刘慧荣 +5 位作者 吴焕淦 张英英 翁志军 秦秀娣 赵继梦 吴璐一 《世界中医药》 CAS 2020年第14期2053-2062,共10页
目的:从维生素D参与免疫调节作用角度探讨隔药灸治疗UC的作用机制。方法:采用4%葡聚糖硫酸钠制备UC大鼠模型。将动物随机分为:正常组、模型组、隔药灸组和SASP组。观察各组大鼠DAI评分、结肠大体形态损伤评分及结肠组织病理学(HPS)评分... 目的:从维生素D参与免疫调节作用角度探讨隔药灸治疗UC的作用机制。方法:采用4%葡聚糖硫酸钠制备UC大鼠模型。将动物随机分为:正常组、模型组、隔药灸组和SASP组。观察各组大鼠DAI评分、结肠大体形态损伤评分及结肠组织病理学(HPS)评分、大鼠血清及结肠组织25(OH)D3、VDR浓度;检测大鼠结肠组织炎性细胞因子IFN-γ、TNF-α的表达和大鼠结肠组织VDR、RXRαmRNA的表达;分析25(OH)D3与治疗后DAI评分、结肠IFN-γ、TNF-α表达之间的相关性。结果:隔药灸显著降低UC大鼠DAI评分、结肠大体形态损伤评分及HPS评分(P<0.05);隔药灸显著升高UC大鼠血清和结肠中25(OH)D3、VDR浓度(P<0.05),以及结肠组织中VDR、RXRαmRNA表达(P<0.05);隔药灸降低UC大鼠结肠组织中IFN-γ、TNF-α表达水平(P<0.05)。大鼠血清25(OH)D3浓度与治疗后DAI评分呈负相关,结肠25(OH)D3浓度分别与结肠IFN-γ、TNF-α表达呈显著负相关。结论:隔药灸可抑制UC大鼠结肠IFN-γ、TNF-α的表达,升高其血清和结肠中的维生素D及其受体的浓度;UC大鼠肠道炎症与低浓度的维生素D呈负相关。 展开更多
关键词 隔药灸 溃疡性结肠炎 25羟基维生素D3 维生素D受体 Γ干扰素 肿瘤坏死因子-α
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截石位在闭合复位交锁髓内钉内固定治疗胫骨干骨折中的应用研究 被引量:8
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作者 罗显德 段戡 +1 位作者 覃仁镭 张翼升 《中国修复重建外科杂志》 CAS CSCD 北大核心 2020年第9期1101-1105,共5页
目的探讨截石位在闭合复位交锁髓内钉内固定治疗胫骨干骨折中的应用价值。方法回顾分析2015年1月—2018年5月78例采用闭合复位交锁髓内钉内固定治疗的胫骨干骨折患者临床资料,其中33例采用截石位(试验组),45例采用传统平卧位(对照组)。... 目的探讨截石位在闭合复位交锁髓内钉内固定治疗胫骨干骨折中的应用价值。方法回顾分析2015年1月—2018年5月78例采用闭合复位交锁髓内钉内固定治疗的胫骨干骨折患者临床资料,其中33例采用截石位(试验组),45例采用传统平卧位(对照组)。两组患者性别、年龄、致伤原因、受伤至入院时间、受伤至手术时间、骨折部位及类型等一般资料比较,差异均无统计学意义(P>0.05),具有可比性。记录两组手术时间、术中出血量、术中透视次数、切开复位例数以及术后切口感染发生情况、骨折愈合情况。采用疼痛视觉模拟评分(VAS)及Harris评分评价疗效。结果两组手术均顺利完成。试验组在手术时间、术中出血量、术中透视次数及切开复位例数方面均优于对照组,差异有统计学意义(P<0.05)。术后试验组1例(3.03%)、对照组3例(6.67%)发生切口感染,感染发生率差异有统计学意义(χ~2=0.139,P=0.045)。其余患者切口均Ⅰ期愈合。X线片复查显示两组骨折均愈合,试验组骨折愈合时间为(5.30±1.33)个月,对照组为(5.98±1.80)个月,差异无统计学意义(t=-1.815,P=0.073)。两组术前及术后3、6、12个月VAS评分以及膝关节、踝关节Harris评分差异均无统计学意义(P>0.05);术后3 d试验组VAS评分明显低于对照组,膝关节、踝关节Harris评分高于对照组,差异均有统计学意义(P<0.05)。结论闭合复位交锁髓内钉内固定治疗胫骨干骨折时,采用截石位有利于骨折复位操作,具有出血少、手术时间短、透视次数少等优点。 展开更多
关键词 胫骨干骨折 截石位 交锁髓内钉 闭合复位 内固定
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北京城区夏季VOCs初始体积分数特征及来源解析 被引量:2
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作者 张博韬 景宽 +5 位作者 王琴 安欣欣 鹿海峰 王陈婧 王友峰 刘保献 《环境科学》 EI CAS CSCD 北大核心 2024年第1期81-92,共12页
为明确北京市夏季VOCs体积分数特征及来源,在2022年5~8月对北京城区VOCs开展了连续监测并利用光化学比值法计算了初始体积分数.结果表明:①研究期间,北京城区初始φ(TVOCs)为(30.0±11.5)×10^(-9),其中含氧VOCs和烷烃占比达到3... 为明确北京市夏季VOCs体积分数特征及来源,在2022年5~8月对北京城区VOCs开展了连续监测并利用光化学比值法计算了初始体积分数.结果表明:①研究期间,北京城区初始φ(TVOCs)为(30.0±11.5)×10^(-9),其中含氧VOCs和烷烃占比达到34.2%和33.2%,体积分数较高的物种是丙酮、乙烷、乙醛和丙烷等低碳物质.②北京城区初始TVOCs体积分数略微呈现单峰变化趋势,11:00达到峰值,下午略有降低.③各排放物质中对O3生成贡献较大的主要是异戊二烯、乙醛、正丁醛和乙烯等物质,而对二次有机气溶胶生成贡献较大的主要是甲苯、异戊二烯、间/对-二甲苯和乙苯物质.④基于初始体积分数的PMF解析发现,老化背景及二次源(30%)对北京市VOCs贡献率最高,机动车源(25%)则是最主要的一次人为源,此外溶剂及燃油挥发源贡献率16%,燃烧源贡献率11%,工业过程源贡献率9%,天然源贡献率9%.⑤影响北京市的人为源主要来自东部和南部区域,天然源则来自西部和西北部区域.研究显示,应进一步削减机动车排放,开展区域联防联控降低整个区域VOCs水平是最终控制北京市VOCs的有效手段. 展开更多
关键词 挥发性有机物(VOCs) 北京 初始体积分数 来源解析 浓度权重轨迹(CWT)
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北京市四季典型污染过程PM_(2.5)酸度与二次硝酸盐形成机制 被引量:1
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作者 王友峰 景宽 +8 位作者 沈秀娥 王琴 王陈婧 富佳明 张博韬 张健 曹阳 张珂 刘保献 《中国环境科学》 EI CAS CSCD 北大核心 2024年第8期4167-4178,共12页
基于北京市城区点位2022年观测数据,运用ISORROPIA-Ⅱ模型分析冬季霾、春季沙尘、夏季高臭氧与秋季PM_(2.5)与臭氧复合污染共4次典型污染过程PM_(2.5)的酸度特征,获得气溶胶pH值与硝酸盐快速增长的演变规律.结果表明,北京市气溶胶pH值... 基于北京市城区点位2022年观测数据,运用ISORROPIA-Ⅱ模型分析冬季霾、春季沙尘、夏季高臭氧与秋季PM_(2.5)与臭氧复合污染共4次典型污染过程PM_(2.5)的酸度特征,获得气溶胶pH值与硝酸盐快速增长的演变规律.结果表明,北京市气溶胶pH值为中度酸性,四次污染过程pH值范围分别为3.59~5.07,3.70~7.76,2.44~6.15和2.80~4.69.4次污染过程气溶胶pH值呈正态分布,pH值中位数分别为4.60、4.59、3.91和4.09.冬季霾污染过程气溶胶水含量最高,其气溶胶pH值最大.春季沙尘污染过程气溶胶pH值呈双峰分布,受到人为源与天然源共同影响.夏、秋两次污染过程PM_(2.5)酸性分别为最强和次强,可能与大气氧化性增强促进酸性气体被氧化有关.夏季气温高气溶胶pH值低,HNO_(3)倾向于向气相分配,硝酸盐占比最低(22%);秋季气溶胶pH值昼低夜高,有利于硝酸盐的夜间积累,硝酸盐占比与冬、春两次污染过程相当(27%~28%).北京大气气态NH_(3)充分富余,HNO_(3)与NH_(3)的中和(均相)反应为NO_(3)^(-)的主要生成机制,气溶胶中NH_(4)^(+)也相对富余,气溶胶中(NH_(4))_(2)SO_(4)、NH_(4)NO_(3)和NH_(4)Cl均可以充分耦合.研究显示,较高的气溶胶水含量和气溶胶pH值是污染期间硝酸盐快速增长的原因,针对气态前体物NH_(3)和NO_(x)的进一步减排是控制北京大气细颗粒的有效手段. 展开更多
关键词 北京 典型污染过程 ISORROPIA-Ⅱ模型 气溶胶pH值 二次硝酸盐生成机制
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健康行动过程取向理论在护理健康教育中的应用进展
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作者 张应嵩(综述) 沈云霞(审校) +5 位作者 陶款 张晓琳 李勤 董传黎 蔺小芳 周子尾 《现代医药卫生》 2024年第18期3192-3196,共5页
健康教育的目的之一是促进健康相关行为的转变,健康行动过程取向(HAPA)理论解释了行为改变的过程,为行为改变的干预提供了理论框架。该文对HAPA理论的内涵、特点、在护理健康教育中的应用进行综述,以期增加护理人员对HAPA理论的认识,推... 健康教育的目的之一是促进健康相关行为的转变,健康行动过程取向(HAPA)理论解释了行为改变的过程,为行为改变的干预提供了理论框架。该文对HAPA理论的内涵、特点、在护理健康教育中的应用进行综述,以期增加护理人员对HAPA理论的认识,推动该理论在护理健康教育中的应用,为促进患者的行为改变提供依据。 展开更多
关键词 健康行动过程取向理论 护理 健康教育 行为改变 综述
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Inhibitory Effect of Flavonoid Glycosides from Chlorophytum comosum on Nasopharyngeal Carcinoma 5-8F Cells and Its Mechanism
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作者 Chenliang CHU Xinchen WANG +2 位作者 kuan LU Liang qin Lu JIN 《Medicinal Plant》 2024年第1期66-70,共5页
[Objectives]To study the inhibitory activity of two flavonoid glycosides isolated from Chlorophytum comosum Laxum R.Br on human nasopharyngeal carcinoma(NPC)cell line 5-8F in vitro and its mechanism.[Methods]The flavo... [Objectives]To study the inhibitory activity of two flavonoid glycosides isolated from Chlorophytum comosum Laxum R.Br on human nasopharyngeal carcinoma(NPC)cell line 5-8F in vitro and its mechanism.[Methods]The flavonoid glycosides were isolated and purified from the ethanol alcoholic extract of the roots of Liliaceae plant Chlorophytum comosum by silica gel column chromatography,macroporous resin column chromatography,Sephadex LH-20,and reverse column chromatography(ODS).The inhibitory activity of flavonoid glycosides on human nasopharyngeal carcinoma cells was analyzed by CCK-8 method,and the potential mechanism was preliminarily analyzed by molecular docking.[Results]Two flavonoid glycosides were identified as isovitexin 2″-0-rhamnoside and 7-2″-di-O-β-glucopyranosylisovitexin.Two flavonoid glycosides showed promising inhibitory effect on human nasopharyngeal carcinoma cell line 5-8F,with IC_(50) values of 24.8 and 27.5μmol/L,respectively.Molecular docking results showed that the potential targets of two flavonoid glycosides include CyclinD1,Bcl-2β-Catenin,ILK,TGF-β,in addition,two glycosides showed higher predicted binding affinity towards CyclinD1,which verifies the cytotoxicity of the two compounds on human nasopharyngeal carcinoma cell line 5-8F in vitro.[Conclusions]Two flavonoid glycosides are the active molecules in Chlorophytum comosum that can inhibit the proliferation of human nasopharyngeal carcinoma cells,and have the potential to be used in the research and development of anti nasopharyngeal carcinoma drugs. 展开更多
关键词 Chlorophytum comosum Laxum R.Br. Flavonoid glycosides 5-8F cells Antitumor mechanism
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Active tuning of electromagnetically induced transparency from chalcogenide-only metasurface 被引量:5
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作者 kuan Liu Meng Lian +2 位作者 Kairong qin Shuang Zhang Tun Cao 《Light(Advanced Manufacturing)》 2021年第3期45-55,共11页
Electromagnetically induced transparency(EIT)is a coherent optical process that provides a narrow transparent peak within a broad absorption line in an atomic medium.All-dielectric metasurface analogues of EIT have en... Electromagnetically induced transparency(EIT)is a coherent optical process that provides a narrow transparent peak within a broad absorption line in an atomic medium.All-dielectric metasurface analogues of EIT have enabled new developments in the nanophotonics field for obtaining smaller,more effective slow-light devices and highly sensitive detectors without a quantum approach.However,the dynamic control of the EIT response of all-dielectric metasurfaces has been rarely reported hitherto for the near-infrared(N-IR)region,although a broader range of applications will be enabled by a reconfigurable EIT system.In this study,we realise a chalcogenide(germanium antimony telluride,GST)metasurface,which possesses a dynamically tunable EIT response by optically driving the amorphous-crystalline phase change in the GST medium.Only a few tens of nanometres thick,the nanostructured GST film exhibits Mie resonances that are spectrally modified via laser-induced phase transitions,offering a high relative modulation contrast of 80%in the N-IR region.Moreover,an extreme dispersion that results in the‘slow light’behaviour is observed within this transparency‘window’.Furthermore,the group delay of the N-IR beam switches reversibly under the phase transition.The measurement is consistent with both numerical simulation results and phenomenological modelling.Our work facilitates the development of new types of compact ultrafast N-IR holograms,filtering,and ultrasensitive detectors. 展开更多
关键词 transition. TRANSPARENCY DIELECTRIC
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Toughening Mechanism of Nanocomposite Physical Hydrogels Fabricated by a Single Gel Network with Dual Crosslinking-- The Roles of the Dual Crosslinking Points 被引量:5
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作者 fu-kuan shi ming zhong +2 位作者 li-qin zhang xiao-ying liu 谢续明 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2017年第1期25-35,共11页
A facile method to fabricate tough and highly stretchable polyacrylamide (PAM) nanocomposite physical hydrogel (NCP gel) was proposed. The hydrogels are dually crosslinked single network with the PAM grafted vinyl... A facile method to fabricate tough and highly stretchable polyacrylamide (PAM) nanocomposite physical hydrogel (NCP gel) was proposed. The hydrogels are dually crosslinked single network with the PAM grafted vinyl hybrid silica nanoparticles (VSNPs) as the analogous covalent crosslinking points and the reversible hydrogen bonds among the PAM chains as the physical crosslinking points. In order to further elucidate the toughening mechanism of the PAM NCP gel, especially to understand the role of the dual crosslinking points, the PAM hybrid hydrogels (H gels) and a series of poly(acrylamide-co-dimethylacrylamide) (P(AM-co-DMAA)) NCP gels were designed and fabricated. Their mechanical properties were compared with those of the PAM NCP gels. The PAM H gels are prepared by simply mixing the PAM chains with bare silica nanoparticles (SNPs). Relative to the poor mechanical properties of the PAM H gel, the PAM NCP gel is remarkably tough and stretchable and also generates large number of micro-cracks to stop notch propagation, indicating the important role of PAM grafted VSNPs in toughening the NCP gel. In the P(AM-co-DMAA) NCP gels, the P(AM-co- DMAA) chains are grafted on VSNPs and the polydimethylacrylamide (PDMAA) only forms very weak hydrogen bonds between themselves. It is found that mechanical properties of the PAM NCP gel, such as the tensile strength and the elongation at break, are enhanced significantly, but those of the P(AM-co-DMAA) NCP gels decreased rapidly with decreasing AM content. This result reveals the role of the hydrogen bonds among the grafted polymer chains as the physical crosslinking points in toughening the NCP gel. 展开更多
关键词 Dual crosslinking single network Nanocomposite physical hydrogel Toughening mechanism
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北京城区不同组分 PM_(2.5)散射特性及来源分析 被引量:1
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作者 曹阳 王陈婧 +3 位作者 景宽 王琴 刘保献 安欣欣 《环境科学》 EI CAS CSCD 北大核心 2023年第2期658-669,共12页
近年来北京城区PM_(2.5)浓度下降伴随其中二次离子占比升高,为探索不同组分PM_(2.5)散射特性及其来源,于2020年12月至2021年11月开展了小时分辨率的PM_(2.5)及其组分浓度和散射系数的连续在线监测,分析了PM_(2.5)组分及散射的特征和来源... 近年来北京城区PM_(2.5)浓度下降伴随其中二次离子占比升高,为探索不同组分PM_(2.5)散射特性及其来源,于2020年12月至2021年11月开展了小时分辨率的PM_(2.5)及其组分浓度和散射系数的连续在线监测,分析了PM_(2.5)组分及散射的特征和来源.结果表明,研究期间北京城区PM_(2.5)最主要组分为NO^(-)_(3),PM_(2.5)中ω(NO^(-)_(3))和ω(SNA)分别为24%和46%.根据浓度和组分占比将PM_(2.5)划分为6种类型:优型出现频率最高,为56%,四季分布均匀,PM_(2.5)中ω(SNA)、ω(OM)和ω(FS)相当,分别为32%、 32%和28%;沙尘(D)型和OM(O)型全年出现频率较低,分别以FS和OM为主要组分,PM_(2.5)中ω(FS)和ω(OM)分别为66%和46%,主要分布于春季和夏季;OM+SO_(4)^(2-)(OS)型多分布于夏季午后,OM+NO^(-)_(3)(ON)型多分布于冬季凌晨和上午,NO^(-)_(3)(N)型多分布于春季及每日07:00前后.低湿(相对湿度<40%)条件,N型PM_(2.5)的MSE最高,为4.3m^(2)·g^(-1),D型最低,为2.1m^(2)·g^(-1),体现了二次盐类的高散射能力,MSE随相对湿度增加而增大,高湿(相对湿度>80%)条件,多类型PM_(2.5)的MSE升高为低湿的1.5~1.8倍,SAE结果显示颗粒物粒径随相对湿度增加有增大趋势.非高湿条件下,小时分辨率IMPROVE重构散射系数与实测值拟合较好,R介于0.81~0.97之间,除D型外,斜率介于1.00~1.21之间,N型拟合结果最好;高湿条件下R和斜率分别介于0.82~0.84和0.48~0.53之间.全年B_(sca)为203.8 Mm^(-1),N型PM_(2.5)贡献率最大,为53%,大颗粒NH_(4)NO_(3)为主要贡献物质,优型PM_(2.5)的B_(sca)为67.2 Mm^(-1),小颗粒OM为主要贡献物质,与全年B_(sca)(dry)相比,B_(sca)放大了1.5倍,其中SNA贡献放大了1.8~2.1倍.NO^(-)_(3)和相对湿度同时在07:00前后出现最高峰值,导致NH_(4)NO_(3)在该时刻B_(sca)达到最大,SO_(4)^(2-)峰值主要出现在16:00,(NH_(4))_(2)SO_(4)的B_(sca)峰值出现在04:00,OM浓度和其B_(sca)日变化曲线趋势较一致,双峰分别出现在13:00和20:00.春冬� 展开更多
关键词 北京城区 PM_(2.5)组分 散射系数 IMPROVE重构 日变化 潜在源区
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Fe-N-C nanostick derived from 1D Fe-ZIFs for electrocatalytic oxygen reduction
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作者 Jiayu Huang kuan Chang +4 位作者 Qi Liu Yameng Xie Zhijia Song Zhiping Zheng qin kuang 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2023年第10期21-27,共7页
The slow oxygen reduction process at the cathode and the scarcity of platinum-based metals lead to limited applications in fuel cells and metal-air cells.Recently,transition metal and nitrogen co-doped carbon-based ca... The slow oxygen reduction process at the cathode and the scarcity of platinum-based metals lead to limited applications in fuel cells and metal-air cells.Recently,transition metal and nitrogen co-doped carbon-based catalysts(M–N–C)are regarded as the most prospective non-precious metal catalysts for future fuel cell applications.It is verified theoretically and experimentally that the metal and nitrogen coordination structure is the main catalytic activity center of oxygen reduction reaction(ORR),so constructing M–N–C materials with high available surface area and structural stability is an effective way to accelerate ORR.Herein,we deliberately synthesize a one-dimensional ZIF structure to fabricate one-dimensional porous Fe–N–C nanostick via two-step pyrolysis.Excitingly,the as-synthesized exhibited an outstanding ORR activity in alkaline medium(E_(1/2)of 0.928 V),as well as superior stability(only changed 7 mV after 10,000 cycles in alkaline medium).Our results show that the reduction of electrocatalyst dimensionality can promote mass transport and increase the accessibility of active sites,thus optimizing their performance in ORR.This work is a good demonstration of the importance of a rational design of catalyst structure for efficient ORR. 展开更多
关键词 Oxygen reduction reaction Metal-organic frameworks M-N-C catalysts ELECTROCATALYSTS
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Acidic Magnetic Biocarbon-Enabled Upgrading of Biomass-Based Hexanedione into Pyrroles
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作者 Zhimei Li kuan Tian +3 位作者 Keping Wang Zhengyi Li Haoli qin Hu Li 《Journal of Renewable Materials》 EI 2023年第11期3847-3865,共19页
Sustainable acquisition of bioactive compounds from biomass-based platform molecules is a green alternative for existing CO_(2)-emitting fossil-fuel technologies.Herein,a core–shell magnetic biocarbon catalyst functi... Sustainable acquisition of bioactive compounds from biomass-based platform molecules is a green alternative for existing CO_(2)-emitting fossil-fuel technologies.Herein,a core–shell magnetic biocarbon catalyst functionalized with sulfonic acid(Fe3O4@SiO_(2)@chitosan-SO_(3)H,MBC-SO_(3)H)was prepared to be efficient for the synthesis of various N-substituted pyrroles(up to 99% yield)from bio-based hexanedione and amines under mild conditions.The abundance of Bronsted acid sites in the MBC-SO_(3)H ensured smooth condensation of 2,5-hexanedione with a variety of amines to produce N-substituted pyrroles.The reaction was illustrated to follow the conventional Pall-Knorr coupling pathway,which includes three cascade reaction steps:amination,loop closure and dehydration.The prepared MBC-SO_(3)H catalyst could effectively activate 2,5-hexanedione,thus weakening the dependence of the overall conversion process on the amine nucleophilicity.The influence of different factors(e.g.,reaction temperature,time,amount of catalyst,molar ratio of substrates,and solvent type)on the reaction activity and selectivity were investigated comprehensively.Moreover,the MBC-SO_(3)H possessed excellent thermochemical stability,reusability,and easy separation due to the presence of magnetic core-shell structures.Notably,there was no activity attenuation after 5 consecutive catalytic experiments.This work demonstrates a wide range of potential applications of developing functionalized core-shell magnetic materials to construct bioactive backbones from biomass-based platform molecules. 展开更多
关键词 Magnetic materials biomass conversion heterogeneous catalysis sustainable chemistry
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原发性良性阵发性位置性眩晕患者VEMP异常率的临床观察 被引量:4
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作者 陈建勇 孙夏雨 +8 位作者 沈佳丽 汪玮 王璐 贺宽 张勤 马孝宝 沈敏 陈向平 杨军 《山东大学耳鼻喉眼学报》 CAS 2020年第5期51-55,共5页
目的比较原发性初发和复发良性阵发性位置性眩晕(BPPV)患者的前庭诱发肌源性电位(VEMPs)特点,探索原发性BPPV屡次复发的可能发病机制。方法收集首次就诊即确诊为单侧原发性BPPV的患者57例,其中初发患者36例,复发患者21例。所有患者均进... 目的比较原发性初发和复发良性阵发性位置性眩晕(BPPV)患者的前庭诱发肌源性电位(VEMPs)特点,探索原发性BPPV屡次复发的可能发病机制。方法收集首次就诊即确诊为单侧原发性BPPV的患者57例,其中初发患者36例,复发患者21例。所有患者均进行气导声刺激条件下的颈肌VEMP(cVEMP)和眼肌VEMP(oVEMP)检查,对比分析初发组和复发组cVEMP和oVEMP结果的差异。结果(1)初发和复发BPPV组在性别、发病侧别及受累半规管均无统计学差异(P>0.05),年龄存在统计学差异(P<0.05);(2)57例BPPV患者中21例(36.84%)cVEMP异常,35例(61.40%)oVEMP异常,oVEMP异常率更高(P<0.05);分别对初发组中和复发组中的cVEMP和oVEMP异常率进行比较,结果显示两组oVEMP异常率更高,差异具有统计学意义(P<0.05);(3)初发BPPV组cVEMP异常有16例(44.45%),复发BPPV组异常有5例(23.81%);初发BPPV组oVEM异常有19例(52.79%),复发BPPV组中oVEMP异常有16例(76.19%);两组cVEMP和oVEMP异常率均无统计学差异(P>0.05);(4)复发2次组和复发3次以上组,与初发组进行VEMPs异常率比较显示三组间cVEMP及oVEMP异常率均无统计学差异(P>0.05)。结论原发性初发组和复发组BPPV患者的cVEMP和oVEMP异常率差异均无统计学意义,提示耳石器功能异常可能不是原发性BPPV患者反复复发的发病机制。 展开更多
关键词 良性阵发性位置性眩晕 颈肌前庭诱发肌源性电位 眼肌前庭诱发肌源性电位 初发性 复发性
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Design and test of post-seat weeding machine for paddy 被引量:4
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作者 Liang Tian Chengmao Cao +2 位作者 kuan qin Liangfei Fang Jun Ge 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2021年第3期112-122,共11页
Aiming to solve problems in organic rice weeding a type of post-seat weeding machine was designed for rice paddies.The differences in the strengths and lengths of the root systems between the rice seedlings and the we... Aiming to solve problems in organic rice weeding a type of post-seat weeding machine was designed for rice paddies.The differences in the strengths and lengths of the root systems between the rice seedlings and the weeds were studied,and the motion track of the weeding wheel was analyzed to obtain the structural parameters of the weeding wheel.Then,the structural model of the weeding wheel was designed.The interaction process between the weeding wheel and soil in the paddy fields was simulated and analyzed based on the discrete element method,so as to investigate the working resistance change tendency of the weeding wheel and the orderliness of the soil disturbances.An orthogonal test was designed in this study,with three factors:the hoeing depth,the rotation rate of the weeding wheel,and the forward speed of the device.The influences of different operation parameters of the weeding machine on the weeding torque and soil disturbance speed were obtained based on a variance analysis of the test results.A multi-index comprehensive weighted scoring method was used to evaluate the simulation results.A soil bin test was conducted to verify the simulation results.Field experiments were carried out to test the working performance of the weeding machine.The comprehensive scoring results indicated that a better working performance of the weeding operation could be obtained when the hoeing depth was 50 mm,the rotation rate of the weeding wheel was 240 r/min,and the forward speed was 0.6 m/s.The results of the soil bin test were consistent with the simulation results.The results of the field experiment revealed that the weeding machine met the requirements for organic rice weeding.These results can provide a reference for the design of weeding machines for paddy fields. 展开更多
关键词 paddy field WEEDING structural parameters discrete element method SOIL
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