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捻针时真、假穴不同中枢激活效应的脑功能MRI 被引量:41
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作者 方继良 Timo krings +2 位作者 Juergen Weidemann Ingo Meister Armin Thron 《中华放射学杂志》 CAS CSCD 北大核心 2004年第12期1281-1284,共4页
目的 利用功能磁共振 (fMRI)观察捻针针刺方法对大脑的作用。方法 用盲法随机分别针刺 13例正常人左侧太冲、丘墟和假穴 ,手法采用捻针和不捻针 ,利用 1 5TMR仪行全脑功能成像 ,用SPM99b分析图像。结果 发现只在真穴捻针针刺时有更... 目的 利用功能磁共振 (fMRI)观察捻针针刺方法对大脑的作用。方法 用盲法随机分别针刺 13例正常人左侧太冲、丘墟和假穴 ,手法采用捻针和不捻针 ,利用 1 5TMR仪行全脑功能成像 ,用SPM99b分析图像。结果 发现只在真穴捻针针刺时有更强的激活效应 ,有显著性意义的Brodmann激活区域为 :针刺太冲穴激活了左右顶叶BA4 0区 ,右额叶BA4 7和 10区 ,右丘脑 ,左小脑 ;针刺丘墟穴激活了左右顶叶BA4 0区 ,右顶叶BA2区 ,左额叶BA9、10、4 4区 ,左岛叶BA13区 ,左颞叶BA2 2区 ,右颞叶BA4 2区 ,右壳核 ,左小脑。两真穴激活部位部分相同 ,部分不同。在假穴捻针对不捻针的研究中 ,未见到有显著性意义的激活区。结论 真穴捻针时可能对皮层神经活动有较特异的作用 ,而假穴未观察到此种现象 ,推测这可能是针刺治疗作用的机制之一。 展开更多
关键词 激活 针刺 MRI 中枢 颞叶 BA 脑功能 图像 TMR 显著性
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卒中介入治疗培训指南:国际多学会共识文件 被引量:2
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作者 Lavine SD Cockroft K +120 位作者 Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 《国际脑血管病杂志》 2017年第5期396-399,共4页
1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。
关键词 缺血性卒中 培训指南 介入治疗 文件 学会 国际 血管闭塞 动脉闭塞
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Smoking behavior of HIV-infected patients
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作者 Till Neumann Nico Reinsch +6 位作者 Stefan Esser Peter krings Thomas Konorza Tanja Woiwoid Michael Miller Norbert Brockmeyer Raimund Erbel 《Health》 2010年第8期913-918,共6页
Recent reports describe an increased rate of cardiovascular events in smoking HIV-infected subjects. However, a lot is still unknown about smoking in this patient population. The purpose of the study was to analyze sm... Recent reports describe an increased rate of cardiovascular events in smoking HIV-infected subjects. However, a lot is still unknown about smoking in this patient population. The purpose of the study was to analyze smoking behavior in HIV-infected subjects as a risk factor of coro-nary atherosclerosis and determine its effect on the probability of coronary events. We analyzed the cardiovascular risk factors of 294 HIV-infected adults (age: 42.1 ? 10.1 years;77% males). An elevated tobacco abuse was observed in 63.6% of the HIV-infected patients. Tobacco use was much more common in HIV-infected males than in females (67.8% vs. 49.2%;p 0.2). Analysing the way of infection and the status of smoking, patients with HIV-infection acquired by heterosexual contact exhibited sig-nificantly lower rates of smoking compared with patients with HIV-infection acquired by MSM (man having sex with man) or by intravenous drug abuse (52.7% vs. 67.4%/82.1%, p < 0.01). The effect of smoking on the 10yrs. probability of coronary events determined by Framingham- equation was superior compared with all other classic cardiovascular risk factors. HIV-infected patients exhibited an increased tobacco use. Knowledge about smoking behavior in this pa-tient population is essential to evaluate the risk of cardiovascular events and to implicate prevention strategies for HIV-infected subjects. 展开更多
关键词 Human IMMUNODEFICIENCY VIRUS ATHEROSCLEROSIS SMOKING TOBACCO CONSUMPTION
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Digital Media as a Game-Changer in B2B Buyer-Vendor Relationships
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作者 Werner krings Roger Palmer +1 位作者 Michael J Harrison Alessandro Inversini 《Journal of Sustainable Business and Economics》 2022年第3期27-43,共17页
Purpose:The article examines the role of digital and,in particular,social media in business-to-business marketing in the international software industry.The authors responded to calls for empirical research on how the... Purpose:The article examines the role of digital and,in particular,social media in business-to-business marketing in the international software industry.The authors responded to calls for empirical research on how these media impact buyer-vendor relationships and the conjunction of the marketing and sales processes,particularly the distribution of complex software solutions.This paper develops a digital framework and discusses the managerial consequences.Design/methodology/approach:The model arises by merging themes derived from literature,experts,and job descriptions.Mixed Methods included conducting semi-structured interviews across marketing,business development,and sales executives from buyers,vendors,and third parties of various industries,supplemented by a survey of 530+executives.Findings:Multinational companies secure competitive advantage through agile business processes to improve buyer-vendor relationships in the digital era.Digital media enable vendors to interact continuously with buyers,gather intelligence,and foster mutually beneficial,trustworthy,long-term relationships.The objective is to prompt transactions and secure revenue streams.Research limitations/implications:The outcomes of this research center on North America,Western Europe(including the UK),and DACH(Germany-Austria-Switzerland),affecting the generalizability.Originality/value:The research is novel and bridges several gaps concerning industrial relationships in digitalization:it merges buyer,vendor,and third-party’s perspectives on an international scale.It provides deeper insights into existing and new relationships by identifying relevant digital/social media platforms,the underlying usage motivation,and fundamental B2B processes.Finally,it equips practitioners with metrics to improve performance. 展开更多
关键词 Digital/social media BUSINESS-TO-BUSINESS Buyer-Vendor relationships Marketing&Sales alignment Business performance
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运载火箭和人造地球卫星发动机装置用容器和壳体的制造方法
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作者 Radtke W krings H. 张振广 《国外导弹与航天运载器》 1992年第11期74-78,共5页
本文扼要介绍了宇航火箭系统发动机装置用容器和壳体的制造方法,使用此种先进工艺,可以制造出质量轻、可靠性好且廉价的多种产品,满足了宇航系统的特殊要求。
关键词 远地点发动机 贮箱 运载火箭
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面向经营过程和团队的规划岛──在订单处理过程中顺利实施质量管理的成功因素
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作者 H.Luczak J.Otzipka K.krings 《工业工程与管理》 1997年第6期35-39,共5页
在分环节的企业结构内,规划岛对于如何以最佳的方式进行订单处理具有重要的意义。它在几方面对生产过程的质量、绩效制定和资源消耗有较大的影响。规划岛可以通过创造通用而全封闭的生产过程、调节回路及其自身适当的活动空间,来提高... 在分环节的企业结构内,规划岛对于如何以最佳的方式进行订单处理具有重要的意义。它在几方面对生产过程的质量、绩效制定和资源消耗有较大的影响。规划岛可以通过创造通用而全封闭的生产过程、调节回路及其自身适当的活动空间,来提高生产的满意程度和内在动力。此外,它还可以通过对各种经验和技巧进行跨专业的结合,为产品经营过程和组织机构本身展现出巨大的改进和创新潜力,因而,最终在生产领域中起战略领导的作用。所以,规划岛是在进行订单处理过程中实现通用而全面的质量管理的一个重要因素。 展开更多
关键词 经营过程 规划岛 订单处理 质量管理 企业
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SATB2表达模式有助于卵巢转移性结直肠或阑尾肿瘤与卵巢原发性黏液性或子宫内膜样肿瘤的鉴别 被引量:21
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作者 Moh M krings G +2 位作者 Ates D 许文静(摘译) 余英豪(审校) 《临床与实验病理学杂志》 CAS CSCD 北大核心 2016年第5期527-527,共1页
由于部分卵巢外的转移性肿瘤可显示出相似的显微镜下特点及免疫表型特征,给卵巢黏液性肿瘤的确诊带来困难,如原发于结直肠、阑尾、胃、胰腺、子宫内膜样腺癌的转移可与卵巢原发性黏液性囊腺瘤、交界性黏液性肿瘤及黏液腺癌相似。
关键词 卵巢黏液性肿瘤 子宫内膜样腺癌 转移性肿瘤 阑尾肿瘤 卵巢外 原发性 结直肠 表达模式
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Facial emotion perception in schizophrenia: Does sex matter? 被引量:2
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作者 Jasmine Mote Ann M kring 《World Journal of Psychiatry》 SCIE 2016年第2期257-268,共12页
AIM: To review the literature on sex differences in facial emotion perception(FEP) across the schizophrenia spectrum. METHODS: We conducted a systematic review of empirical articles that were included in five separate... AIM: To review the literature on sex differences in facial emotion perception(FEP) across the schizophrenia spectrum. METHODS: We conducted a systematic review of empirical articles that were included in five separate meta-analyses of FEP across the schizophrenia spectrum, including meta-analyses that predominantly examined adults with chronic schizophrenia, people with early(onset prior to age 18) or recent-onset(experiencing their first or second psychotic episode or illness duration less than 2 years) schizophrenia, and unaffected first-degree relatives of people with schizophrenia. We also examined articles written in English(from November 2011 through June 2015) that were not included in the aforementioned metaanalyses through a literature search in the Pub Med database. All relevant articles were accessed in full text. We examined all studies to determine the sample sizes, diagnostic characteristics, demographic information, methodologies, results, and whether each individual study reported on sex differences. The results from the meta-analyses themselves as well as the individual studies are reported in tables and text. RESULTS: We retrieved 134 articles included in five separate meta-analyses and the Pub Med database that examined FEP across the schizophrenia spectrum. Of these articles, 38 examined sex differences in FEP. Thirty of these studies did not find sex differences in FEP in either chronically ill adults with schizophrenia, early-onset or recently diagnosed people with schizophrenia, or first-degree relatives of people with schizophrenia. Of the eight studies that found sex differences in FEP, three found that chronically ill women outperformed men, one study found that girls with early-onset schizophrenia outperformed boys, and two studies found that women(including first-degree relatives, adults with schizophrenia, and the healthy control group) outperformed men on FEP tasks. In total, six of the eight studies that examined sex differences in FEP found that women outperformed men across thesch 展开更多
关键词 Clinical high risk EMOTION FACIAL EMOTION PERCEPTION Gender Recent-onset SCHIZOPHRENIA SCHIZOPHRENIA SEX differences
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What gets in the way of social engagement in schizophrenia? 被引量:1
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作者 Lauren P Weittenhiller Megan E Mikhail +2 位作者 Jasmine Mote Timothy R Campellone Ann M kring 《World Journal of Psychiatry》 SCIE 2021年第1期13-26,共14页
BACKGROUND Social engagement-important for health and well-being-can be difficult for people with schizophrenia.Past research indicates that despite expressing interest in social interactions,people with schizophrenia... BACKGROUND Social engagement-important for health and well-being-can be difficult for people with schizophrenia.Past research indicates that despite expressing interest in social interactions,people with schizophrenia report spending less time with others and feeling lonely.Social motivations and barriers may play an important role for understanding social engagement in schizophrenia.AIM To investigate how people with schizophrenia describe factors that impede and promote social engagement.METHODS We interviewed a community sample of people with(n=35)and without(n=27)schizophrenia or schizoaffective disorder about their social interactions with friends and family over the past week and planned social activities for the coming week.We reviewed the interview transcripts and developed a novel coding system to capture whether interactions occurred,who had initiated the contact,and frequency of reported social barriers(i.e.,internal,conflict-based,logistical)and social motivations(i.e.,instrumental,affiliative,obligation-based).We also assessed symptoms and functioning.RESULTS People with schizophrenia were less likely than people without schizophrenia to have spent time with friends[t(51.04)=2.09,P=0.042,d=0.51)],but not family.People with schizophrenia reported more social barriers than people without schizophrenia[F(1,60)=10.55,P=0.002,ηp2=0.15)]but did not differ in reported social motivations.Specifically,people with schizophrenia reported more internal[t(45.75)=3.40,P=0.001,d=0.83)]and conflict-based[t(40.11)=3.03,P=0.004,d=0.73)]barriers than people without schizophrenia.Social barriers and motivations were related to real-world social functioning for people with schizophrenia,such that more barriers were associated with more difficulty in close relationships(r=-0.37,P=0.027)and more motivations were associated with better community functioning(r=0.38,P=0.024).CONCLUSION These findings highlight the importance of assessing first person accounts of social barriers and motivations to better understand social eng 展开更多
关键词 Social engagement SCHIZOPHRENIA Social motivation Social barriers
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撞击事件及其对生命起源、演化和分布的影响
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作者 张秋明 D.A.kring 《国土资源科技进展》 2000年第5期56-59,共4页
1前言 撞击成坑作用对我们行星的地质演化和生物演化都有影响,这点已变得越来越清楚。这种观点源于阿波罗飞船升空的时代,但是,直到通过研究后把界定中生代结束时间的生物集群灭绝与Chicxulub撞击事件联系起来之后,才得到人们广泛... 1前言 撞击成坑作用对我们行星的地质演化和生物演化都有影响,这点已变得越来越清楚。这种观点源于阿波罗飞船升空的时代,但是,直到通过研究后把界定中生代结束时间的生物集群灭绝与Chicxulub撞击事件联系起来之后,才得到人们广泛承认。该事件还说明了某种作用如何能够毁灭某些生物,又如何能够为其他生物创造机遇, 展开更多
关键词 撞击成坑作用 地质演化 生命起源 生物集群灭绝 环境影响 行星撞击灾变
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气垫船动力学ACVSIM模型的初步验证(二)
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作者 W.Milewski B.Connell +2 位作者 B.Petersen D.kring 孙新(编译) 《橡塑资源利用》 CAS 2021年第3期33-38,共6页
人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以... 人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以及使用2007年秋季获得的基线深裙作为模型尺度的LCAC进行初始验证研究的结果。该仿真工具提供了研究设计修改的影响的能力,以及模型载具缩放问题与多耦合物理系统的问题。 展开更多
关键词 模型集成 第一原理 物理系统 流体动力学 气垫船 耐波性 数值模拟模型 ACV
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气垫船动力学 ACVSIM 模型的初步验证(三)
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作者 W.Milewski B.Connell +2 位作者 B.Petersen D.kring 孙新(编译) 《橡塑资源利用》 CAS 2021年第4期34-38,共5页
人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以... 人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以及使用2007年秋季获得的基线深裙作为模型尺度的LCAC进行初始验证研究的结果。该仿真工具提供了研究设计、修改产生影响的能力,以及模型载具缩放问题与多耦合物理系统的问题。 展开更多
关键词 模型集成 第一原理 物理系统 流体动力学 气垫船 耐波性 数值模拟模型 ACV
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气垫船动力学ACVSIM模型的初步验证(一)
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作者 W.Milewski B.Connell +2 位作者 B.Petersen D.kring 孙新(编译) 《橡塑资源利用》 CAS 2021年第2期32-38,共7页
人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以... 人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以及使用2007年秋季获得的基线深裙作为模型尺度的LCAC进行初始验证研究的结果。该仿真工具提供了研究设计修改的影响的能力,以及模型载具缩放问题与多耦合物理系统的问题。 展开更多
关键词 模型集成 第一原理 物理系统 流体动力学 气垫船 耐波性 数值模拟模型 ACV
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气垫船动力学ACVSIM模型的初步验证(四)
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作者 W.Milewski B.Connell +2 位作者 B.Petersen D.kring 孙新(编译) 《橡塑资源利用》 CAS 2021年第5期35-38,共4页
人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以... 人们对改进气垫载具的耐波性动力学预测能力重新产生了兴趣。这导致了第一原理数值模拟模型ACVSIM(Milewski等人,2007)的发展,该模型集成了气垫和裙摆动力学模型与基于高阶样条的流体动力学边界元模型。本文概述了ACVSIM最近的改进,以及使用2007年秋季获得的基线深裙作为模型尺度的LCAC进行初始验证研究的结果。该仿真工具提供了研究设计、修改产生影响的能力,以及模型载具缩放问题与多耦合物理系统的问题。 展开更多
关键词 模型集成 第一原理 物理系统 流体动力学 气垫船 耐波性 数值模拟模型 ACV
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免疫组化标记Pan-TRK有助于乳腺分泌性癌的诊断 被引量:1
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作者 Harrison B T Fowler E +2 位作者 krings G 王婷(摘译) 余英豪(审校) 《临床与实验病理学杂志》 CAS CSCD 北大核心 2020年第8期946-946,共1页
乳腺分泌性癌是一种特殊类型的乳腺癌,其分子特征为t(12;15)(p13;q25)平衡易位导致ETV6-NTRK3基因融合。由于Pan-TRK抗体能够有效识别TRK蛋白近C-末端保守序列,有文献报道使用免疫组化Pan-TRK抗体有助于识别其他肿瘤类型的NTRK基因重排... 乳腺分泌性癌是一种特殊类型的乳腺癌,其分子特征为t(12;15)(p13;q25)平衡易位导致ETV6-NTRK3基因融合。由于Pan-TRK抗体能够有效识别TRK蛋白近C-末端保守序列,有文献报道使用免疫组化Pan-TRK抗体有助于识别其他肿瘤类型的NTRK基因重排。作者采用兔单克隆抗体对24例乳腺分泌性癌、203例其他类型乳腺癌组织芯片和15例组织学相似病变进行Pan-TRK免疫组化染色,并对其染色强度和定位进行评估。 展开更多
关键词 乳腺癌组织 肿瘤类型 染色强度 平衡易位 特殊类型 基因融合 分子特征 免疫组化染色
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火烧地球村
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作者 DavidA.kring DanielD.Durda +1 位作者 柯江华 周松 《科学(中文版)》 2004年第2期40-47,共8页
恐龙突然终结于一颗小行星(或慧星)的撞击,这点在今天已成了人们的常识,鲜为人知的是这些恐龙以及其他物种确切的灭绝过程,以及此后生态系统又是如何复原的.这场灾难的破坏性远远超过了生物经常必须克服的攻击.那颗小行星(或彗星)以超... 恐龙突然终结于一颗小行星(或慧星)的撞击,这点在今天已成了人们的常识,鲜为人知的是这些恐龙以及其他物种确切的灭绝过程,以及此后生态系统又是如何复原的.这场灾难的破坏性远远超过了生物经常必须克服的攻击.那颗小行星(或彗星)以超过音速40倍的速度从天而降撞向地球.它体积巨大,在前端撞到地面时,其后端至少还在一般客机的飞行高度上.它产生的爆炸力相当于100万亿吨TNT,释放的能量超过从那以后6500万年来地球上发生的任何事件. 展开更多
关键词 天体碰撞 地球 火灾 物种灭绝 白垩纪 人类进化
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Polarization Measurements in Radiative Electron Capture into High-Z Ions
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作者 F.Bosch A.Gumberidze +13 位作者 S.Hagmann C.Kozhuharov Th.krings A.OrsicMuthig D.Protic D.Sierpowski U.Spillmann Z.Stachura A.Warczak MaXinwen S.Tachenov Th.Stoehlker D.Banas H.F.Beyer 《近代物理研究所和兰州重离子加速器实验室年报:英文版》 2002年第1期77-77,共1页
Recently, there has been great interest in the linear polarization of photons produced by radiative electron capture (REC, the time reversed photoionization in ion-atom collisions). No such data are available for the ... Recently, there has been great interest in the linear polarization of photons produced by radiative electron capture (REC, the time reversed photoionization in ion-atom collisions). No such data are available for the high-Z regime till now. By using high efficiency by by a new generation of segmented germanium detectors that have energy as well as position resolution this field can be investigated experimentally. The 展开更多
关键词 高电荷态离子 俘获电子辐射 极化测量 散射截面 观测角 原子物理学 能量谱
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