A low pressure system from the southwest Bay of Bengal between 8-10 June, 1991 brought heavy and continuous rainfall over different parts of Maharashtra. This 3-day heavy rainspell over Maharashtra has been analysed t...A low pressure system from the southwest Bay of Bengal between 8-10 June, 1991 brought heavy and continuous rainfall over different parts of Maharashtra. This 3-day heavy rainspell over Maharashtra has been analysed toassess its magnitudes of point as well as areal rainfall. The analysis showed that there were 74 stations which received3-day total rainfall during 8-10 June exceeding their respective normal June rainfall. The areal raindepths obtainedfrom the rainstorm of June, 1991 have been compared with similar data of past severe rainstorms of the region whichshowed that June, 1991 rainstorm yielded higher magnitudes of raindepths upto certain size of areas. A relationshiphas also been developed between point to areal rainfall of this rainstorm for 1-3 day durations for obtaining arealraindepths.展开更多
The intention behind the present work was to develop a microsponge based novel dosage form for sustained delivery of domperidone.Quasi-emulsion solvent diffusion method was employed using Eudragit RS-100 with various ...The intention behind the present work was to develop a microsponge based novel dosage form for sustained delivery of domperidone.Quasi-emulsion solvent diffusion method was employed using Eudragit RS-100 with various drug-polymer ratios for the preparation of microsponges.For optimization purposes,several factors which affect microparticles’physical properties were investigated.Characterization techniques followed for the formed microsponges were DSC,FTIR,SEM,XRD and particle size analysis,along with morphology,drug loading and in vitro drug release.It was found that there were no chemical interactions between drugs and polymers used as per DSC and FTIR results.The drug-polymer ratio showed remarkable impact on drug content,encapsulation efficiency and particle size.SEM micrographs revealed that microsponges were spherical in shape with porous surface,and had 104±0.22μm mean particle size.The microsponges were then loaded in capsules followed by in vitro drug release study;which depicted that microsponges with drug-polymer ratio of 1:2 were more proficient to give extended drug release of 76.38%at the end of 8 h,superior in contrast to conventional marketed formulation Domstal®,which got exhausted incredibly earlier by releasing 82.57%drug at the end of 1⁄2 h only.Hence,the developed microsponge based formulation of domperidone would be an expectant,promising substitute to conventional therapy of gastroparesis,emesis and alike gastric ailments.展开更多
Herein, we report visible light active mesoporous cadmium bismuth niobate（CBN） nanospheres as a photocatalyst for hydrogen（H） generation from copious hydrogen sulfide（HS）. CBN has been synthesized by solid state...Herein, we report visible light active mesoporous cadmium bismuth niobate（CBN） nanospheres as a photocatalyst for hydrogen（H） generation from copious hydrogen sulfide（HS）. CBN has been synthesized by solid state reaction（SSR） and also using combustion method（CM） at relatively lower temperatures.The as-synthesized materials were characterized using different techniques. X-ray diffraction analysis shows the formation of single phase orthorhombic CBN. Field emission scanning electron microscopy and high resolution-transmission electron microscopy showed the particle size in the range of.5–1 μm for CBN obtained by SSR and 50–70 nm size nanospheres using CM, respectively. Interestingly, nanospheres of size 50–70 nm self assembled with 5–7 nm nanoparticles were observed in case of CBN prepared by CM.The optical properties were studied using UV–visible diffuse reflectance spectroscopy and showed band gap around.0 eV for SSR and 3.1 eV for CM. The slight shift in band gap of CM is due to nanocrystalline nature of material. Considering the band gap in visible region, the photocatalytic activity of CBN for hydrogen production from HS has been performed under visible light. CBN prepared by CM has shown utmost hydrogen evolution i.e. 6912 μmol/h/0.5 g which is much higher than CBN prepared using SSR.The enhanced photocatalytic property can be attributed to the smaller particle size, crystalline nature,high surface area and mesoporous structure of CBN prepared by combustion method. The catalyst was found to be stable, active and can be utilized for water splitting.展开更多
文摘A low pressure system from the southwest Bay of Bengal between 8-10 June, 1991 brought heavy and continuous rainfall over different parts of Maharashtra. This 3-day heavy rainspell over Maharashtra has been analysed toassess its magnitudes of point as well as areal rainfall. The analysis showed that there were 74 stations which received3-day total rainfall during 8-10 June exceeding their respective normal June rainfall. The areal raindepths obtainedfrom the rainstorm of June, 1991 have been compared with similar data of past severe rainstorms of the region whichshowed that June, 1991 rainstorm yielded higher magnitudes of raindepths upto certain size of areas. A relationshiphas also been developed between point to areal rainfall of this rainstorm for 1-3 day durations for obtaining arealraindepths.
文摘The intention behind the present work was to develop a microsponge based novel dosage form for sustained delivery of domperidone.Quasi-emulsion solvent diffusion method was employed using Eudragit RS-100 with various drug-polymer ratios for the preparation of microsponges.For optimization purposes,several factors which affect microparticles’physical properties were investigated.Characterization techniques followed for the formed microsponges were DSC,FTIR,SEM,XRD and particle size analysis,along with morphology,drug loading and in vitro drug release.It was found that there were no chemical interactions between drugs and polymers used as per DSC and FTIR results.The drug-polymer ratio showed remarkable impact on drug content,encapsulation efficiency and particle size.SEM micrographs revealed that microsponges were spherical in shape with porous surface,and had 104±0.22μm mean particle size.The microsponges were then loaded in capsules followed by in vitro drug release study;which depicted that microsponges with drug-polymer ratio of 1:2 were more proficient to give extended drug release of 76.38%at the end of 8 h,superior in contrast to conventional marketed formulation Domstal®,which got exhausted incredibly earlier by releasing 82.57%drug at the end of 1⁄2 h only.Hence,the developed microsponge based formulation of domperidone would be an expectant,promising substitute to conventional therapy of gastroparesis,emesis and alike gastric ailments.
基金Department of Electronics and Information Technology(Deit Y),Government of India for financial supportB.P.H.E Society's Ahmednagar College Ahmednagar for financial supportNanocrystalline Materials Group C-MET for the kind support
文摘Herein, we report visible light active mesoporous cadmium bismuth niobate（CBN） nanospheres as a photocatalyst for hydrogen（H） generation from copious hydrogen sulfide（HS）. CBN has been synthesized by solid state reaction（SSR） and also using combustion method（CM） at relatively lower temperatures.The as-synthesized materials were characterized using different techniques. X-ray diffraction analysis shows the formation of single phase orthorhombic CBN. Field emission scanning electron microscopy and high resolution-transmission electron microscopy showed the particle size in the range of.5–1 μm for CBN obtained by SSR and 50–70 nm size nanospheres using CM, respectively. Interestingly, nanospheres of size 50–70 nm self assembled with 5–7 nm nanoparticles were observed in case of CBN prepared by CM.The optical properties were studied using UV–visible diffuse reflectance spectroscopy and showed band gap around.0 eV for SSR and 3.1 eV for CM. The slight shift in band gap of CM is due to nanocrystalline nature of material. Considering the band gap in visible region, the photocatalytic activity of CBN for hydrogen production from HS has been performed under visible light. CBN prepared by CM has shown utmost hydrogen evolution i.e. 6912 μmol/h/0.5 g which is much higher than CBN prepared using SSR.The enhanced photocatalytic property can be attributed to the smaller particle size, crystalline nature,high surface area and mesoporous structure of CBN prepared by combustion method. The catalyst was found to be stable, active and can be utilized for water splitting.
