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Recent Advances in Fibrinogen Research in Colorectal Cancer 被引量:1
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作者 Wenjing Jiang Di Wang junyan yu 《Journal of Biosciences and Medicines》 2023年第4期28-38,共11页
Colorectal Cancer (CRC) is a common malignant tumour of the gastrointestinal tract in China, with increasing morbidity and mortality rates year by year. Most patients are in the middle and late stage when diagnosed, a... Colorectal Cancer (CRC) is a common malignant tumour of the gastrointestinal tract in China, with increasing morbidity and mortality rates year by year. Most patients are in the middle and late stage when diagnosed, and its high mortality and poor prognosis have seriously threatened the health and life. Fibrinogen (FIB) is mainly used as a coagulation factor in the body to participate in the process of coagulation and haemostasis, and is the main protein in the coagulation process. In recent years, studies at home and abroad have shown that FIB levels correlate with the diagnosis, outcome prediction and prognosis of CRC, and some of the findings are still controversial. This article aims to review the related research and new progress of the relationship between FIB and CRC in recent years. 展开更多
关键词 FIBRINOGEN Colorectal Cancer Coagulation Function
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服役期内模块式加筋土挡墙稳定性研究
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作者 姚占勇 张正超 +1 位作者 蒋红光 于君彦 《土木工程》 2017年第2期206-214,共9页
针对加筋土挡墙在服役期内出现的变形过大甚至失稳问题,本文结合某高速公路实际工程,研究筋带蠕变导致的墙面变形对挡墙稳定性的影响。首先,通过现场监测获得了该挡墙5处典型断面的侧向变形分布特征,发现经过8年的服役,挡土墙的最大侧... 针对加筋土挡墙在服役期内出现的变形过大甚至失稳问题,本文结合某高速公路实际工程,研究筋带蠕变导致的墙面变形对挡墙稳定性的影响。首先,通过现场监测获得了该挡墙5处典型断面的侧向变形分布特征,发现经过8年的服役,挡土墙的最大侧向位移为13.5 cm,侧向位移/墙高值为0.87%。其次,通过建立现场加筋土挡墙的二维有限元模型,分析了在该变形量下挡墙侧向位移、墙后土压力、筋带应力应变及挡墙整体稳定性。数值结果表明:由于挡墙侧向变形的增大,加筋土挡墙的整体安全系数由竣工时的1.85降低至1.28,存在失稳的危险。因此,有必要对该挡土墙的危险断面采取相应的工程加固措施,并改善挡土墙的防排水结构布置。 展开更多
关键词 加筋土挡土墙 现场监测 数值分析 侧向位移 稳定性
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