AIM： To study the appearances of acute interstitial edematous pancreatitis （IEP） on non-enhanced MR imaging. METHODS： A total of 53 patients with IEP diagnosed by clinical features and laboratory findings were und...AIM： To study the appearances of acute interstitial edematous pancreatitis （IEP） on non-enhanced MR imaging. METHODS： A total of 53 patients with IEP diagnosed by clinical features and laboratory findings were underwent MR imaging. MR imaging sequences included fast spoiled gradient echo （FSPGR） fat saturation axial T1-weighted imaging, gradient echo T1-weighted （in phase）, single shot fast spin echo （SSFSE） T2-weighted, respiratory triggered （R-T） T2-weighted with fat saturation, and MR cholangiopancreatography. Using the MR severity score index, pancreatitis was graded as mild （0-2 points）, moderate （3-6 points） and severe （7-10 points）. RESULTS： Among the 53 patients, IEP was graded as mild in 37 patients and as moderate in 16 patients. Forty-seven of 53 （89%） patients had at least one abnormality on MR images. Pancreas was hypointense relative to liver on FSPGR T1-weighted images in 18.9% of patients, and hyperintense in 25% and 30% on SSFSE T2-weighted and R-T T2-weighted images, respectively. The prevalences of the findings of IEP on R-T T2-weighted images were, respectively, 85% for pancreatic fascial plane, 77% for left renal fascial plane, 55% for peripancreatic fat stranding, 42% for right renal fascial plane, 45% for perivascular fluid, 40% for thickened pancreatic Iobular septum and 25% for peripancreatic fluid, which were markedly higher than those on in-phase or SSFSE T2-weighted images （P 〈 0.001）. CONCLUSION： IEP primarily manifests on non- enhanced MR images as thickened pancreatic fascial plane, left renal fascial plane, peripancreatic fat stranding, and peripancreatic fluid. R-T T2-weighted imaging is more sensitive than in-phase and SSFSE T2- weighted imaging for depicting IER展开更多
Background:Tuberculosis infection still places a great burden on HIV-infected individuals in China and other developing countries.Knowledge of the survival of HIV-infected patients with pulmonary tuberculosis(PTB)woul...Background:Tuberculosis infection still places a great burden on HIV-infected individuals in China and other developing countries.Knowledge of the survival of HIV-infected patients with pulmonary tuberculosis(PTB)would provide important insights for the clinical management of this population,which remains to be well described in current China.Methods:HIV-infected patients with PTB admitted to Shanghai Public Health Clinical Center from January 2011 to December 2015 were retrospectively enrolled.In this cohort,the survival prognosis was estimated by the Kaplan-Meier method,while univariate and multivariate Cox proportional hazards models were used to determine the risk factors affecting mortality.Results:After reviewing 4914 admitted patients with HIV infection,359 PTB cases were identified.At the time of PTB diagnosis,the patients’median CD4+T cell count was 51/mm3(IQR:23-116),and 27.30%of patients(98/359)were on combination antiretroviral therapy(cART).For the 333 cases included in the survival analysis,the overall mortality was 15.92%(53/333)during a median 27-month follow-up.The risk factors,including age older than 60 years(HR:3.18;95%CI:1.66-6.10),complication with bacterial pneumonia(HR:2.64;95%CI:1.30-5.35),diagnosis delay(HR:2.60;95%CI:1.42-4.78),CD4+T cell count less than 50/mm3(HR:2.38;95%CI:1.27-4.43)and pulmonary atelectasis(HR:2.20;95%CI:1.05-4.60),might independently contribute to poor survival.Among patients without cART before anti-TB treatment,the later initiation of cART(more than 8 weeks after starting anti-TB treatment)was found to increase the mortality rate(OR:4.33;95%CI:1.22-15.36),while the initiation of cART within 4-8 weeks after starting anti-TB treatment was associated with the fewest deaths(0/14).Conclusions:The subjects in this study conducted in the cART era were still characterized by depressed immunological competence and low rates of cART administration,revealing possible intervention targets for preventing TB reactivation in HIV-infected individuals under current circumstances展开更多
An accelerator-based Boron Neutron Capture Therapy(AB-BNCT)experimental facility called D-BNCT01 has been recently completed and is currently able to generate a high-intensity neutron beam for BNCTrelated research.In ...An accelerator-based Boron Neutron Capture Therapy(AB-BNCT)experimental facility called D-BNCT01 has been recently completed and is currently able to generate a high-intensity neutron beam for BNCTrelated research.In this study,we perform several experiments involving water phantoms to validate the Monte Carlo simulation results and analyze the neutron beam characteristics.According to our measurements,D-BNCT01 can generate a neutron flux about 1.2×10^(8)n/cm^(2)/s at the beam port using a 5 kW proton beam.Our results also show that the thermal neutron flux depth distribution inside the water phantom is in good agreement with simulations.We conclude that D-BNCT01 may be effectively employed for BNCT research.展开更多
BACKGROUND A growing body of research indicates significant differences between left-sided colon cancers(LCC)and right-sided colon cancers(RCC).Pan-immune-inflammation value(PIV)is a systemic immune response marker th...BACKGROUND A growing body of research indicates significant differences between left-sided colon cancers(LCC)and right-sided colon cancers(RCC).Pan-immune-inflammation value(PIV)is a systemic immune response marker that can predict the prognosis of patients with colon cancer.However,the specific distinction between PIV of LCC and RCC remains unclear.AIM To investigate the prognostic and clinical significance of PIV in LCC and RCC patients.METHODS This multicenter retrospective cohort study included 1510 patients with colon cancer,comprising 801 with LCC and 709 with RCC.We used generalized lifting regression analysis to evaluate the relative impact of PIV on disease-free survival(DFS)in these patients.Kaplan-Meier analysis,as well as univariate and multivariate analyses,were used to examine the risk factors for DFS.The correlation between PIV and the clinical characteristics was statistically analyzed in these patients.RESULTS A total of 1510 patients{872 female patients(58%);median age 63 years[interquartile ranges(IQR):54-71];patients with LCC 801(53%);median follow-up 44.17 months(IQR 29.67-62.32)}were identified.PIV was significantly higher in patients with RCC[median(IQR):214.34(121.78-386.72)vs 175.87(111.92-286.84),P<0.001].After propensity score matching,no difference in PIV was observed between patients with LCC and RCC[median(IQR):182.42(111.88-297.65)vs 189.45(109.44-316.02);P=0.987].PIV thresholds for DFS were 227.84 in LCC and 145.99 in RCC.High PIV(>227.84)was associated with worse DFS in LCC[PIV-high:Adjusted hazard ratio(aHR)=2.39;95%confidence interval:1.70-3.38;P<0.001]but not in RCC(PIV-high:aHR=0.72;95%confidence interval:0.48-1.08;P=0.114).CONCLUSION These findings suggest that PIV may predict recurrence in patients with LCC but not RCC,underscoring the importance of tumor location when using PIV as a colon cancer biomarker.展开更多
BACKGROUND The management of polyps involving the appendiceal orifice(AO)presents notable challenges.Endoscopic resection is frequently hindered by operational complexities,a heightened risk of incomplete removal,and ...BACKGROUND The management of polyps involving the appendiceal orifice(AO)presents notable challenges.Endoscopic resection is frequently hindered by operational complexities,a heightened risk of incomplete removal,and an elevated risk of procedural complications,including appendicitis.Conversely,surgical resection may entail unnecessary excision of intestinal segments,leading to potential morbidity.CASE SUMMARY Here,we reported two patients who presented with polyps deeply situated within the AO,with indistinct boundaries making it challenging to ensure completeness using traditional endoscopic resection.To overcome these challenges,we em-ployed combined endo-laparoscopic surgery(CELS),achieving curative resection without postoperative complications.CONCLUSION The application of CELS in managing polyps involving the AO is emerging as a safe and effective treatment modality.展开更多
Stretchable electronics that monitor joint activity and treat diseases based on liquid metal could be used in the development of healthcare applications.Such devices can be seamlessly integrated with human skin.Howeve...Stretchable electronics that monitor joint activity and treat diseases based on liquid metal could be used in the development of healthcare applications.Such devices can be seamlessly integrated with human skin.However,most high-precision microstructures and complex patterns are difficult to fabricate due to the limitations of conventional fabrication solutions,resulting in suboptimal performance under practical conditions.Here,a liquid-metal stretchable system utilizing natural leaf veins was reported as microstructures,which was based on a biomimetic concept and utilized an all-solution process for the preparation of complex microstructures.The systems are ultra-high tensile(800%tensile strain),environmentally stable(20 days)and mechanically durable(300-cycle).The system can accurately recognize the wearer's finger bending level as well as simple gesture signals.At the same time,the system acts as a wearable heater,which can realize the fast heating behavior of heating up to 50℃in 3 min under the human body-safe voltage(1.5 V).The tensile stability is demonstrated by the heterogeneous integration of lasers(405 nm)with the system interconnects for a stretchable and wearable light source.展开更多
The coexistence of multi-component active sites like single-atom sites,diatomic sites(DAS)and nanoclusters is shown to result in superior performances in the hydrogen evolution reaction(HER).Metal diatomic sites are m...The coexistence of multi-component active sites like single-atom sites,diatomic sites(DAS)and nanoclusters is shown to result in superior performances in the hydrogen evolution reaction(HER).Metal diatomic sites are more complex than single-atom sites but their unique electronic structures can lead to significant enhancement of the HER kinetics.Although the synthesis and identification of DAS is usually challenging,we report a simple access to a diatomic catalyst by anchoring Co-Ru DAS on nitrogen-doped carbon supports along with Ru nanoparticles(NPs).Experimental and theoretical results revealed the atomic-level characteristics of Co-Ru sites,their strong electronic coupling and their synergy with Ru NPs within the catalyst.The unique electronic structure of the catalyst resulted in an excellent HER activity and stability in alkaline media.This work provides a valuable insight into a widely applicable design of diatomic catalysts with multi-component active sites for highly efficient HER electrocatalysis.展开更多
Pt/CeO_(2)-C catalysts with CeO_(2)pre-calcined at 300-600 ℃were synthesized by combining hydrothermal calcination and wet im-pregnation.The effects of the pre-calcined CeO_(2)on the performance of Pt/CeO_(2)-C catal...Pt/CeO_(2)-C catalysts with CeO_(2)pre-calcined at 300-600 ℃were synthesized by combining hydrothermal calcination and wet im-pregnation.The effects of the pre-calcined CeO_(2)on the performance of Pt/CeO_(2)-C catalysts in methanol oxidation were investigated.The Pt/CeO_(2)-C catalysts with pre-calcined CeO_(2)at 300-600 ℃showed an average particle size of 2.6-2.9 nm and exhibited better methanol elec-tro-oxidation catalytic activity than the commercial Pt/C catalyst.In specific,the Pt/CeO_(2)-C catalysts with pre-calcined CeO_(2)at 400 ℃dis-played the highest electrochemical surface area value of 68.14 m2·g−1 and If/Ib ratio(the ratio of the forward scanning peak current density(If)and the backward scanning peak current density(Ib))of 1.26,which are considerably larger than those(53.23 m2·g−1 and 0.79,respectively)of the commercial Pt/C catalyst,implying greatly enhanced CO tolerance.展开更多
BACKGROUND Intestinal flora disorder(IFD)poses a significant challenge after laparoscopic colonic surgery,and no standard criteria exists for its diagnosis and treatment.AIM To analyze the clinical features and risk f...BACKGROUND Intestinal flora disorder(IFD)poses a significant challenge after laparoscopic colonic surgery,and no standard criteria exists for its diagnosis and treatment.AIM To analyze the clinical features and risk factors of IFD.METHODS Patients with colon cancer receiving laparoscopic surgery were included using propensity-score-matching(PSM)methods.Based on the occurrence of IFD,patients were categorized into IFD and non-IFD groups.The clinical characteristics and treatment approaches for patients with IFD were analyzed.Multivariate regression analysis was performed to identify the risk factors of IFD.RESULTS The IFD incidence after laparoscopic surgery was 9.0%(97 of 1073 patients).After PSM,97 and 194 patients were identified in the IFD and non-IFD groups,respectively.The most common symptoms of IFD were diarrhea and abdominal,typically occurring on post-operative days 3 and 4.All patients were managed conservatively,including modulation of the intestinal flora(90.7%),oral/intravenous application of vancomycin(74.2%),and insertion of a gastric/ileus tube for decompression(23.7%).Multivariate regression analysis identified that preoperative intestinal obstruction[odds ratio(OR)=2.79,95%CI:1.04–7.47,P=0.041]and post-operative antibiotics(OR=8.57,95%CI:3.31–23.49,P<0.001)were independent risk factors for IFD,whereas pre-operative parenteral nutrition(OR=0.12,95%CI:0.06–0.26,P<0.001)emerged as a protective factor.CONCLUSION A stepwise approach of probiotics,vancomycin,and decompression could be an alternative treatment for IFD.Special attention is warranted post-operatively for patients with pre-operative obstruction or early use of antibiotics.展开更多
BACKGROUND The efficacy of conversion therapy for patients with unresectable hepatocellular carcinoma(HCC)is a common clinical concern.AIM To analyse the prognostic factors of overall survival(OS)in patients with unre...BACKGROUND The efficacy of conversion therapy for patients with unresectable hepatocellular carcinoma(HCC)is a common clinical concern.AIM To analyse the prognostic factors of overall survival(OS)in patients with unresectable HCC who received conversion therapy.METHODS One hundred and fifty patients who met the inclusion criteria were enrolled and divided into a training cohort(n=120)and a validation cohort(n=30).Using the independent risk factors in the training cohort,a nomogram model was constructed to predict OS for patients treated with transarterial chemoembolization following hepatic resection.The nomogram was internally validated with the bootstrapping method.The predictive performance of nomogram was assessed by Harrell’s concordance index(C-index),calibration plot and timedependent receiver operating characteristic curves and compared with six other conventional HCC staging systems.RESULTS Multivariate Cox analysis identified that albumin,blood urea nitrogen,gamma-glutamyl transpeptidase to platelet ratio,platelet to lymphocyte ratio,macrovascular invasion and tumour number were the six independent prognostic factors correlated with OS in nomogram model.The C-index in the training cohort and validation cohort were 0.752 and 0.807 for predicting OS,which were higher than those of the six conventional HCC staging systems(0.563 to 0.715 for the training cohort and 0.458 to 0.571 for the validation cohort).The calibration plots showed good consistency between the nomogram prediction of OS and the actual observations of OS.Decision curve analyses indicated satisfactory clinical utility.With a total nomogram score of 196,patients were accurately classified into low-risk and high-risk groups.Furthermore,we have deployed the model into online calculators that can be accessed for free at https://ctmodelforunresectablehcc.shinyapps.io/DynNomapp/.CONCLUSION The nomogram achieved optimal individualized prognostication of OS in HCC patients who received conversion therapy,which could be a useful clinical tool to h展开更多
Hemorrhagic shock is a life-threatening disease often encountered in emergency departments(EDs).Hemorrhagic shock caused by extensive bleeding from multiple sites is often associated with high mortality and morbidity....Hemorrhagic shock is a life-threatening disease often encountered in emergency departments(EDs).Hemorrhagic shock caused by extensive bleeding from multiple sites is often associated with high mortality and morbidity.In recent years,resuscitative endovascular balloon occlusion of the aorta(REBOA)has been widely used in traumatic hemorrhagic shock and is considered to be an effective resuscitation measure.[1]Some studies reported that REBOA was also effective for non-traumatic hemorrhage.[2,3]In this study,we report a case of hemorrhagic shock caused by acute upper gastrointestinal bleeding that was successfully treated and received REBOA to obtain a transition time.This report may provide feasible options for emergency physicians,gastroenterologists,or surgeons to more actively treat refractory gastrointestinal bleeding.展开更多
Ultra-high molecular weight polyethylene(UHMWPE)fiber composite has been extensively used to construct lightweight protective structures against ballistic impacts,yet little is known about its performance when subject...Ultra-high molecular weight polyethylene(UHMWPE)fiber composite has been extensively used to construct lightweight protective structures against ballistic impacts,yet little is known about its performance when subjected to combined blast and fragment impacts.Built upon a recently developed laboratory-scale experimental technique to generate simulated combined loading through the impact of a fragment-foam composite projectile launched from a light gas gun,the dynamic responses of fullyclamped UHMWPE plates subjected to combined loading were characterized experimentally,with corresponding deformation and failure modes compared with those measured with simulated blast loading alone.Subsequently,to explore the underlying physical mechanisms,three-dimensional(3D)numerical simulations with the method of finite elements(FE)were systematically carried out.Numerical predictions compared favorably well with experimental measurements,thus validating the feasibility of the established FE model.Relative to the case of blast loading alone,combined blast and fragment loading led to larger maximum deflections of clamped UHMWPE plates.The position of the FSP in the foam sabot affected significantly the performance of a UHMWPE target,either enhancing or decreasing its ballistic resistance.When the blast loading and fragment impact arrived simultaneously at the target,its ballistic resistance was superior to that achieved when subjected to fragment impact alone,and benefited from the accelerated movement of the target due to simultaneous blast loading.展开更多
Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-ri...Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-rich area shows a slightly higher oxygen content and a much finer grain size.The Ti−Zr alloys present a good combination of high strength(σs=700−900 MPa)and total elongation(>20%),and solid solution strengthening of oxygen plays a major role.Zr does not influence much the oxygen-induced brittleness due to its high structural similarity to Ti.Therefore,the high value of 0.54 wt.%is still within the critical oxygen content for the ductile-to-brittle transition of Ti and does not degrade the ductility.展开更多
Objective:To screen the anti-inflammatory monomeric compounds isolated from Berchemia lineata(L.)DC and explore the anti-inflammatory mechanism of some compounds based on NF-κB signaling pathway.Methods:LPS was used ...Objective:To screen the anti-inflammatory monomeric compounds isolated from Berchemia lineata(L.)DC and explore the anti-inflammatory mechanism of some compounds based on NF-κB signaling pathway.Methods:LPS was used to induce RAW264.7 to establish a model of cellular inflammatory reaction.CCK-8 method was used to detect the effect of monomer compounds on the activity of RAW264.7 cells.The release of nitric oxide(NO)in the superneant was measured by Griess method,and NO inhibition rate was calculated.The anti-inflammatory activity gradient of some monomeric compounds was also measured.The effects of monomer compound 21 on the secretion of IL-6,TNF-α,NF-κB,COX-2 and iNOS induced by LPS were detected by ELISA.Results:The concentration of monomer compound of Berchemia lineata(L.)DC.was 50μmol/L,and it was administered for 24 h.The results showed that anthraquinone compound No.19 had obvious drug toxicity,while other compounds had weak or no obvious drug toxicity.The concentration was 50μmol/L,and the drug was administered for 12 h.The results showed that all the monomer compounds could inhibit the release of NO to varying degrees,and the highest NO inhibition rate was over 90%,which showed obvious anti-inflammatory activity.NO inhibition rate of No.01 new skeleton compound can reach 70.81%.The results of anti-inflammatory activity gradient showed that the monomer compound of Berchemia lineata(L.)DC.could inhibit the release of NO in a dose-dependent manner.The results of ELISA showed that phenolic compound 21 could inhibit the secretion of IL-6,TNF-α,NF-κB,COX-2 and iNOS in RAW264.7 cells.Conclusion:The monomer compound of Berchemia lineata(L.)DC.has a certain anti-inflammatory activity,among which flavonoids and bibenzyl components isolated from this plant for the first time may be the material basis for its anti-inflammatory activity.The simple phenolic monomer compound 21 may play an anti-inflammatory role by regulating NF-κB signaling pathway.展开更多
Background： A sensitive method is required to detect retinal hamartomas in patients with tuberous sclerosis complex （TSC）. The aim of the present study was to compare the color fundus photography, infrared imaging ...Background： A sensitive method is required to detect retinal hamartomas in patients with tuberous sclerosis complex （TSC）. The aim of the present study was to compare the color fundus photography, infrared imaging （IFG）, and optical coherence tomography （OCT） in the detection rate of retinal hamartoma in patients with TSC. Methods： This study included 11 patients （22 eyes） with TSC, who underwent color fundus photography, IFG, and spectral-domain OCT to detect retinal hamartomas. TSC1 and TSC2 mutations were tested in eight patients. Results： The mean age of the 11 patients was 8.0 ± 2.1 years. The mean spherical equivalent was -0.55 ±1.42 D by autorefraction with cycloplegia. In 11 patients （22 eyes）, OCT, infrared fundus photography, and color fundus photography revealed 26, 18, and 9 hamartomas, respectively. The predominant hamartoma was type I （55.6%）. All the hamartomas that detected by color fundus photography or IFG can be detected by OCT. Conclusion： Among the methods of color fundus photography, IFG, and OCT, the OCT has higher detection rate for retinal hamartoma in TSC patients; therefore, OCT might be promising for the clinical diagnosis of TSC.展开更多
The emergence of eutectic high-entropy alloys(EHEAs)offers new insights into the design of next generation structural alloys,which is due to their stable dual-phase microstructure and outstanding mechanical properties...The emergence of eutectic high-entropy alloys(EHEAs)offers new insights into the design of next generation structural alloys,which is due to their stable dual-phase microstructure and outstanding mechanical properties from room to elevated temperatures.In this work,a series of(CoFe2 NiV0.5Mo0.2)100-xNbx(0≤x≤12)EHEAs were designed and prepared via vacuum arc-melting.Typical eutectic microstructure composing lamellar face-centered cubic solid solution phase and C14 Laves phase appears in the as-cast EHEA when x=9.The microstructure turns to hypoeutectic or hypereutectic when x is below or beyond that critical value accordingly.The volume fraction of the hard Laves phase is proportional to the Nb addition,leading to the strength increment yet at the expense of ductility at room temperature.In particular,the EHEA having4 at%Nb shows a compressive strength of 2.1 GPa with an elongation to fracture of 45%,while EHEAs containing 9 and10 at%Nb exhibit ultrahigh yield strengths of over 1.4 GPa.The effect of Nb addition on the corrosion resistance of this Crfree EHEA system was also studied.The EHEA containing 9 at%Nb has the best anti-corrosion performance in the 3.5 wt%NaCl solution at 298±1 K,indicating a good combination of mechanical and corrosion properties.展开更多
The optical absorption is the most important macroscopic process to characterize the microscopic optical transition in the semiconductor materials. Recently, great enhancement has been observed in the absorption of th...The optical absorption is the most important macroscopic process to characterize the microscopic optical transition in the semiconductor materials. Recently, great enhancement has been observed in the absorption of the active region within a p–n junction. In this paper, Ga As based p–i–n samples with the active region varied from 100 nm to 3 μm were fabricated and it was observed that the external quantum efficiencies are higher than the typical results, indicating a new mechanism beyond the established theories. We proposed a theoretical model about the abnormal optical absorption process in the active region within a strong electric field, which might provide new theories for the design of the solar cells,photodetectors, and other photoelectric devices.展开更多
The employment of lithium metal anode in rechargeable lithium batteries has been hindered by the safety concerns which are associated with the uncontrolled lithium dendrite growth and the unceasing side reactions with...The employment of lithium metal anode in rechargeable lithium batteries has been hindered by the safety concerns which are associated with the uncontrolled lithium dendrite growth and the unceasing side reactions with liquid electrolytes.In this work,we report that the use of Ti-containing solid electrolyte-coated separators can greatly enhance the cycle performances of lithium metal anode in cells using liquid electrolytes.The detailed morphologic studies indicate that more uniform lithium deposition is achieved in cells using Ti-containing solid electrolyte-coated separators than that using Al_(2)O_(3)-coated separators,which is likely due to the modified anode and electrolyte interfacial properties induced by the reactive nature of Ti-containing solid electrolytes with metallic lithium.This work demonstrates an effective strategy to enhance the homogeneity of lithium deposition,which leads to the stable cycling of lithium metal anode in rechargeable lithium-ion batteries.展开更多
Cloud data centers consume a multitude of power leading to the problem of high energy consumption. In order to solve this problem, an energy-efficient virtual machine(VM) consolidation algorithm named PVDE(prediction-...Cloud data centers consume a multitude of power leading to the problem of high energy consumption. In order to solve this problem, an energy-efficient virtual machine(VM) consolidation algorithm named PVDE(prediction-based VM deployment algorithm for energy efficiency) is presented. The proposed algorithm uses linear weighted method to predict the load of a host and classifies the hosts in the data center, based on the predicted host load, into four classes for the purpose of VMs migration. We also propose four types of VM selection algorithms for the purpose of determining potential VMs to be migrated. We performed extensive performance analysis of the proposed algorithms. Experimental results show that, in contrast to other energy-saving algorithms, the algorithm proposed in this work significantly reduces the energy consumption and maintains low service level agreement(SLA) violations.展开更多
The fracture of pipelines caused by corrosion cracks and the resulting oil and gas leakage can lead to great environmentalpollution and economic losses. These negative effects are due to serious corrosion of the plain...The fracture of pipelines caused by corrosion cracks and the resulting oil and gas leakage can lead to great environmentalpollution and economic losses. These negative effects are due to serious corrosion of the plain carbon steels used for armorof flexible pipe in oil and gas transmission medium. However, corrosion resistance of carbon steel armors has yet to beimproved. In this study, the relationship between corrosion resistance and pearlite fraction in the plain carbon steels hasbeen investigated through the application of pulsed electric current. Based on immersion test and electrochemical mea-surement, pulsed electric current increases the corrosion resistance of the plain carbon steels by reducing the fraction ofpearlite phase. Pitting corrosion, which tends to initiate by galvanic corrosion of ferrite and cementite, is therefore inhibiteddue to the decrease in pearlite fraction （mixture of ferrite and cementite） under electropulsing.展开更多
基金Supported by Key project of Science and Technology Research, Ministry of Education, China, No. 206126
文摘AIM： To study the appearances of acute interstitial edematous pancreatitis （IEP） on non-enhanced MR imaging. METHODS： A total of 53 patients with IEP diagnosed by clinical features and laboratory findings were underwent MR imaging. MR imaging sequences included fast spoiled gradient echo （FSPGR） fat saturation axial T1-weighted imaging, gradient echo T1-weighted （in phase）, single shot fast spin echo （SSFSE） T2-weighted, respiratory triggered （R-T） T2-weighted with fat saturation, and MR cholangiopancreatography. Using the MR severity score index, pancreatitis was graded as mild （0-2 points）, moderate （3-6 points） and severe （7-10 points）. RESULTS： Among the 53 patients, IEP was graded as mild in 37 patients and as moderate in 16 patients. Forty-seven of 53 （89%） patients had at least one abnormality on MR images. Pancreas was hypointense relative to liver on FSPGR T1-weighted images in 18.9% of patients, and hyperintense in 25% and 30% on SSFSE T2-weighted and R-T T2-weighted images, respectively. The prevalences of the findings of IEP on R-T T2-weighted images were, respectively, 85% for pancreatic fascial plane, 77% for left renal fascial plane, 55% for peripancreatic fat stranding, 42% for right renal fascial plane, 45% for perivascular fluid, 40% for thickened pancreatic Iobular septum and 25% for peripancreatic fluid, which were markedly higher than those on in-phase or SSFSE T2-weighted images （P 〈 0.001）. CONCLUSION： IEP primarily manifests on non- enhanced MR images as thickened pancreatic fascial plane, left renal fascial plane, peripancreatic fat stranding, and peripancreatic fluid. R-T T2-weighted imaging is more sensitive than in-phase and SSFSE T2- weighted imaging for depicting IER
基金This study was supported by the National Natural Science Foundation of China(NSFC No.81571977 and No.31500697)Medical Science Support Program by Shanghai Science and Technology Committee(No.16411960400).
文摘Background:Tuberculosis infection still places a great burden on HIV-infected individuals in China and other developing countries.Knowledge of the survival of HIV-infected patients with pulmonary tuberculosis(PTB)would provide important insights for the clinical management of this population,which remains to be well described in current China.Methods:HIV-infected patients with PTB admitted to Shanghai Public Health Clinical Center from January 2011 to December 2015 were retrospectively enrolled.In this cohort,the survival prognosis was estimated by the Kaplan-Meier method,while univariate and multivariate Cox proportional hazards models were used to determine the risk factors affecting mortality.Results:After reviewing 4914 admitted patients with HIV infection,359 PTB cases were identified.At the time of PTB diagnosis,the patients’median CD4+T cell count was 51/mm3(IQR:23-116),and 27.30%of patients(98/359)were on combination antiretroviral therapy(cART).For the 333 cases included in the survival analysis,the overall mortality was 15.92%(53/333)during a median 27-month follow-up.The risk factors,including age older than 60 years(HR:3.18;95%CI:1.66-6.10),complication with bacterial pneumonia(HR:2.64;95%CI:1.30-5.35),diagnosis delay(HR:2.60;95%CI:1.42-4.78),CD4+T cell count less than 50/mm3(HR:2.38;95%CI:1.27-4.43)and pulmonary atelectasis(HR:2.20;95%CI:1.05-4.60),might independently contribute to poor survival.Among patients without cART before anti-TB treatment,the later initiation of cART(more than 8 weeks after starting anti-TB treatment)was found to increase the mortality rate(OR:4.33;95%CI:1.22-15.36),while the initiation of cART within 4-8 weeks after starting anti-TB treatment was associated with the fewest deaths(0/14).Conclusions:The subjects in this study conducted in the cART era were still characterized by depressed immunological competence and low rates of cART administration,revealing possible intervention targets for preventing TB reactivation in HIV-infected individuals under current circumstances
基金supported by the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(No.2017ZT07S225)the Institute of High Energy Physics Xie-Jialin Foundation(No.Y95461F)the National Natural Science Foundation of China(No.U1932219).
文摘An accelerator-based Boron Neutron Capture Therapy(AB-BNCT)experimental facility called D-BNCT01 has been recently completed and is currently able to generate a high-intensity neutron beam for BNCTrelated research.In this study,we perform several experiments involving water phantoms to validate the Monte Carlo simulation results and analyze the neutron beam characteristics.According to our measurements,D-BNCT01 can generate a neutron flux about 1.2×10^(8)n/cm^(2)/s at the beam port using a 5 kW proton beam.Our results also show that the thermal neutron flux depth distribution inside the water phantom is in good agreement with simulations.We conclude that D-BNCT01 may be effectively employed for BNCT research.
基金Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-003.
文摘BACKGROUND A growing body of research indicates significant differences between left-sided colon cancers(LCC)and right-sided colon cancers(RCC).Pan-immune-inflammation value(PIV)is a systemic immune response marker that can predict the prognosis of patients with colon cancer.However,the specific distinction between PIV of LCC and RCC remains unclear.AIM To investigate the prognostic and clinical significance of PIV in LCC and RCC patients.METHODS This multicenter retrospective cohort study included 1510 patients with colon cancer,comprising 801 with LCC and 709 with RCC.We used generalized lifting regression analysis to evaluate the relative impact of PIV on disease-free survival(DFS)in these patients.Kaplan-Meier analysis,as well as univariate and multivariate analyses,were used to examine the risk factors for DFS.The correlation between PIV and the clinical characteristics was statistically analyzed in these patients.RESULTS A total of 1510 patients{872 female patients(58%);median age 63 years[interquartile ranges(IQR):54-71];patients with LCC 801(53%);median follow-up 44.17 months(IQR 29.67-62.32)}were identified.PIV was significantly higher in patients with RCC[median(IQR):214.34(121.78-386.72)vs 175.87(111.92-286.84),P<0.001].After propensity score matching,no difference in PIV was observed between patients with LCC and RCC[median(IQR):182.42(111.88-297.65)vs 189.45(109.44-316.02);P=0.987].PIV thresholds for DFS were 227.84 in LCC and 145.99 in RCC.High PIV(>227.84)was associated with worse DFS in LCC[PIV-high:Adjusted hazard ratio(aHR)=2.39;95%confidence interval:1.70-3.38;P<0.001]but not in RCC(PIV-high:aHR=0.72;95%confidence interval:0.48-1.08;P=0.114).CONCLUSION These findings suggest that PIV may predict recurrence in patients with LCC but not RCC,underscoring the importance of tumor location when using PIV as a colon cancer biomarker.
基金Supported by the National High-Level Hospital Clinical Research Funding,No.2022-PUMCH-B-024 and No.2022-PUMCH-A-020Undergraduate Teaching Reform and Innovation Project,No.2022zlgc0108.
文摘BACKGROUND The management of polyps involving the appendiceal orifice(AO)presents notable challenges.Endoscopic resection is frequently hindered by operational complexities,a heightened risk of incomplete removal,and an elevated risk of procedural complications,including appendicitis.Conversely,surgical resection may entail unnecessary excision of intestinal segments,leading to potential morbidity.CASE SUMMARY Here,we reported two patients who presented with polyps deeply situated within the AO,with indistinct boundaries making it challenging to ensure completeness using traditional endoscopic resection.To overcome these challenges,we em-ployed combined endo-laparoscopic surgery(CELS),achieving curative resection without postoperative complications.CONCLUSION The application of CELS in managing polyps involving the AO is emerging as a safe and effective treatment modality.
基金financially supported by the National Key Research and Development Program of China(No.2021YFA1401100)the National Natural Science Foundation of China(Nos.61825403 and 61921005)。
文摘Stretchable electronics that monitor joint activity and treat diseases based on liquid metal could be used in the development of healthcare applications.Such devices can be seamlessly integrated with human skin.However,most high-precision microstructures and complex patterns are difficult to fabricate due to the limitations of conventional fabrication solutions,resulting in suboptimal performance under practical conditions.Here,a liquid-metal stretchable system utilizing natural leaf veins was reported as microstructures,which was based on a biomimetic concept and utilized an all-solution process for the preparation of complex microstructures.The systems are ultra-high tensile(800%tensile strain),environmentally stable(20 days)and mechanically durable(300-cycle).The system can accurately recognize the wearer's finger bending level as well as simple gesture signals.At the same time,the system acts as a wearable heater,which can realize the fast heating behavior of heating up to 50℃in 3 min under the human body-safe voltage(1.5 V).The tensile stability is demonstrated by the heterogeneous integration of lasers(405 nm)with the system interconnects for a stretchable and wearable light source.
基金the National Natural Science Foundation of China(No.22271203)the State Key Laboratory of Organometallic Chemistry of Shanghai Institute of Organic Chemistry(No.KF2021005)the Collaborative Innovation Center of Suzhou Nano Science and Technology,the Priority Academic Program Development of Jiangsu Higher Education Institutions,and the Project of Scientific and Technologic Infrastructure of Suzhou(No.SZS201905).
文摘The coexistence of multi-component active sites like single-atom sites,diatomic sites(DAS)and nanoclusters is shown to result in superior performances in the hydrogen evolution reaction(HER).Metal diatomic sites are more complex than single-atom sites but their unique electronic structures can lead to significant enhancement of the HER kinetics.Although the synthesis and identification of DAS is usually challenging,we report a simple access to a diatomic catalyst by anchoring Co-Ru DAS on nitrogen-doped carbon supports along with Ru nanoparticles(NPs).Experimental and theoretical results revealed the atomic-level characteristics of Co-Ru sites,their strong electronic coupling and their synergy with Ru NPs within the catalyst.The unique electronic structure of the catalyst resulted in an excellent HER activity and stability in alkaline media.This work provides a valuable insight into a widely applicable design of diatomic catalysts with multi-component active sites for highly efficient HER electrocatalysis.
基金This work was financially supported by the National Nat-ural Science Foundation of China(No.51774145).
文摘Pt/CeO_(2)-C catalysts with CeO_(2)pre-calcined at 300-600 ℃were synthesized by combining hydrothermal calcination and wet im-pregnation.The effects of the pre-calcined CeO_(2)on the performance of Pt/CeO_(2)-C catalysts in methanol oxidation were investigated.The Pt/CeO_(2)-C catalysts with pre-calcined CeO_(2)at 300-600 ℃showed an average particle size of 2.6-2.9 nm and exhibited better methanol elec-tro-oxidation catalytic activity than the commercial Pt/C catalyst.In specific,the Pt/CeO_(2)-C catalysts with pre-calcined CeO_(2)at 400 ℃dis-played the highest electrochemical surface area value of 68.14 m2·g−1 and If/Ib ratio(the ratio of the forward scanning peak current density(If)and the backward scanning peak current density(Ib))of 1.26,which are considerably larger than those(53.23 m2·g−1 and 0.79,respectively)of the commercial Pt/C catalyst,implying greatly enhanced CO tolerance.
基金The National High Level Hospital Clinical Research Funding,No.2022-PUMCH-C-005.
文摘BACKGROUND Intestinal flora disorder(IFD)poses a significant challenge after laparoscopic colonic surgery,and no standard criteria exists for its diagnosis and treatment.AIM To analyze the clinical features and risk factors of IFD.METHODS Patients with colon cancer receiving laparoscopic surgery were included using propensity-score-matching(PSM)methods.Based on the occurrence of IFD,patients were categorized into IFD and non-IFD groups.The clinical characteristics and treatment approaches for patients with IFD were analyzed.Multivariate regression analysis was performed to identify the risk factors of IFD.RESULTS The IFD incidence after laparoscopic surgery was 9.0%(97 of 1073 patients).After PSM,97 and 194 patients were identified in the IFD and non-IFD groups,respectively.The most common symptoms of IFD were diarrhea and abdominal,typically occurring on post-operative days 3 and 4.All patients were managed conservatively,including modulation of the intestinal flora(90.7%),oral/intravenous application of vancomycin(74.2%),and insertion of a gastric/ileus tube for decompression(23.7%).Multivariate regression analysis identified that preoperative intestinal obstruction[odds ratio(OR)=2.79,95%CI:1.04–7.47,P=0.041]and post-operative antibiotics(OR=8.57,95%CI:3.31–23.49,P<0.001)were independent risk factors for IFD,whereas pre-operative parenteral nutrition(OR=0.12,95%CI:0.06–0.26,P<0.001)emerged as a protective factor.CONCLUSION A stepwise approach of probiotics,vancomycin,and decompression could be an alternative treatment for IFD.Special attention is warranted post-operatively for patients with pre-operative obstruction or early use of antibiotics.
基金Supported by the National Natural Science Foundation of China,No.82072035Science and Guangzhou Planned Project of Science and Technology,No.202102010028.
文摘BACKGROUND The efficacy of conversion therapy for patients with unresectable hepatocellular carcinoma(HCC)is a common clinical concern.AIM To analyse the prognostic factors of overall survival(OS)in patients with unresectable HCC who received conversion therapy.METHODS One hundred and fifty patients who met the inclusion criteria were enrolled and divided into a training cohort(n=120)and a validation cohort(n=30).Using the independent risk factors in the training cohort,a nomogram model was constructed to predict OS for patients treated with transarterial chemoembolization following hepatic resection.The nomogram was internally validated with the bootstrapping method.The predictive performance of nomogram was assessed by Harrell’s concordance index(C-index),calibration plot and timedependent receiver operating characteristic curves and compared with six other conventional HCC staging systems.RESULTS Multivariate Cox analysis identified that albumin,blood urea nitrogen,gamma-glutamyl transpeptidase to platelet ratio,platelet to lymphocyte ratio,macrovascular invasion and tumour number were the six independent prognostic factors correlated with OS in nomogram model.The C-index in the training cohort and validation cohort were 0.752 and 0.807 for predicting OS,which were higher than those of the six conventional HCC staging systems(0.563 to 0.715 for the training cohort and 0.458 to 0.571 for the validation cohort).The calibration plots showed good consistency between the nomogram prediction of OS and the actual observations of OS.Decision curve analyses indicated satisfactory clinical utility.With a total nomogram score of 196,patients were accurately classified into low-risk and high-risk groups.Furthermore,we have deployed the model into online calculators that can be accessed for free at https://ctmodelforunresectablehcc.shinyapps.io/DynNomapp/.CONCLUSION The nomogram achieved optimal individualized prognostication of OS in HCC patients who received conversion therapy,which could be a useful clinical tool to h
基金supported by a grant from Health Commission of Zhejiang Province“optimization study on partial balloon occlusion of the aorta in traumatic hemorrhagic shock patients(2023KY774)”.
文摘Hemorrhagic shock is a life-threatening disease often encountered in emergency departments(EDs).Hemorrhagic shock caused by extensive bleeding from multiple sites is often associated with high mortality and morbidity.In recent years,resuscitative endovascular balloon occlusion of the aorta(REBOA)has been widely used in traumatic hemorrhagic shock and is considered to be an effective resuscitation measure.[1]Some studies reported that REBOA was also effective for non-traumatic hemorrhage.[2,3]In this study,we report a case of hemorrhagic shock caused by acute upper gastrointestinal bleeding that was successfully treated and received REBOA to obtain a transition time.This report may provide feasible options for emergency physicians,gastroenterologists,or surgeons to more actively treat refractory gastrointestinal bleeding.
基金supported by the National Natural Science Foundation of China(Grant No.12032010,11902155 and 12072250)by the Natural Science Foundation of Jiangsu Province(Grant No.BK20190382)+2 种基金by the Research Fund of State Key Laboratory of Mechanics and Control of Mechanical Structures(Grant No.MCMS-I-0222K01)by the Fund of Prospective Layout of Scientific Research for NUAAby the Foundation for the Priority Academic Program Development of Jiangsu Higher Education Institutions。
文摘Ultra-high molecular weight polyethylene(UHMWPE)fiber composite has been extensively used to construct lightweight protective structures against ballistic impacts,yet little is known about its performance when subjected to combined blast and fragment impacts.Built upon a recently developed laboratory-scale experimental technique to generate simulated combined loading through the impact of a fragment-foam composite projectile launched from a light gas gun,the dynamic responses of fullyclamped UHMWPE plates subjected to combined loading were characterized experimentally,with corresponding deformation and failure modes compared with those measured with simulated blast loading alone.Subsequently,to explore the underlying physical mechanisms,three-dimensional(3D)numerical simulations with the method of finite elements(FE)were systematically carried out.Numerical predictions compared favorably well with experimental measurements,thus validating the feasibility of the established FE model.Relative to the case of blast loading alone,combined blast and fragment loading led to larger maximum deflections of clamped UHMWPE plates.The position of the FSP in the foam sabot affected significantly the performance of a UHMWPE target,either enhancing or decreasing its ballistic resistance.When the blast loading and fragment impact arrived simultaneously at the target,its ballistic resistance was superior to that achieved when subjected to fragment impact alone,and benefited from the accelerated movement of the target due to simultaneous blast loading.
基金Project(51625404)supported by the National Natural Science Foundation for Distinguished Young Scholar of China。
文摘Ti−Zr alloys(oxygen content 0.42−0.54 wt.%)were prepared via powder metallurgy and hot working.The results indicate that the Ti−Zr alloys exhibit Zr-rich and Zr-lean areas with the sameα-phase structure,and the Zr-rich area shows a slightly higher oxygen content and a much finer grain size.The Ti−Zr alloys present a good combination of high strength(σs=700−900 MPa)and total elongation(>20%),and solid solution strengthening of oxygen plays a major role.Zr does not influence much the oxygen-induced brittleness due to its high structural similarity to Ti.Therefore,the high value of 0.54 wt.%is still within the critical oxygen content for the ductile-to-brittle transition of Ti and does not degrade the ductility.
基金This study was supported by National Key Research and Development Program(No.2022YFC3502201)National Natural Science Foundation of China(No.81960762)+3 种基金Guangxi Key Discipline of Traditional Chinese Medicine(No.GZXK-Z-20-62)Guangxi Science and Technology Base and Talent Special Project(No.Guike AD19245183,AD22035052)Guangxi Demonstration Base of External Treatment of Traditional Chinese Medicine(No.14,2019)National Famous TCM Inheritance Studio,National Famous Old TCM Expert Inheritance Studio Construction Project,National Famous TCM Huang Hanru Academic Thinking and Clinical Experience Inheritance and Promotion Center(No.2022V004)。
文摘Objective:To screen the anti-inflammatory monomeric compounds isolated from Berchemia lineata(L.)DC and explore the anti-inflammatory mechanism of some compounds based on NF-κB signaling pathway.Methods:LPS was used to induce RAW264.7 to establish a model of cellular inflammatory reaction.CCK-8 method was used to detect the effect of monomer compounds on the activity of RAW264.7 cells.The release of nitric oxide(NO)in the superneant was measured by Griess method,and NO inhibition rate was calculated.The anti-inflammatory activity gradient of some monomeric compounds was also measured.The effects of monomer compound 21 on the secretion of IL-6,TNF-α,NF-κB,COX-2 and iNOS induced by LPS were detected by ELISA.Results:The concentration of monomer compound of Berchemia lineata(L.)DC.was 50μmol/L,and it was administered for 24 h.The results showed that anthraquinone compound No.19 had obvious drug toxicity,while other compounds had weak or no obvious drug toxicity.The concentration was 50μmol/L,and the drug was administered for 12 h.The results showed that all the monomer compounds could inhibit the release of NO to varying degrees,and the highest NO inhibition rate was over 90%,which showed obvious anti-inflammatory activity.NO inhibition rate of No.01 new skeleton compound can reach 70.81%.The results of anti-inflammatory activity gradient showed that the monomer compound of Berchemia lineata(L.)DC.could inhibit the release of NO in a dose-dependent manner.The results of ELISA showed that phenolic compound 21 could inhibit the secretion of IL-6,TNF-α,NF-κB,COX-2 and iNOS in RAW264.7 cells.Conclusion:The monomer compound of Berchemia lineata(L.)DC.has a certain anti-inflammatory activity,among which flavonoids and bibenzyl components isolated from this plant for the first time may be the material basis for its anti-inflammatory activity.The simple phenolic monomer compound 21 may play an anti-inflammatory role by regulating NF-κB signaling pathway.
文摘Background： A sensitive method is required to detect retinal hamartomas in patients with tuberous sclerosis complex （TSC）. The aim of the present study was to compare the color fundus photography, infrared imaging （IFG）, and optical coherence tomography （OCT） in the detection rate of retinal hamartoma in patients with TSC. Methods： This study included 11 patients （22 eyes） with TSC, who underwent color fundus photography, IFG, and spectral-domain OCT to detect retinal hamartomas. TSC1 and TSC2 mutations were tested in eight patients. Results： The mean age of the 11 patients was 8.0 ± 2.1 years. The mean spherical equivalent was -0.55 ±1.42 D by autorefraction with cycloplegia. In 11 patients （22 eyes）, OCT, infrared fundus photography, and color fundus photography revealed 26, 18, and 9 hamartomas, respectively. The predominant hamartoma was type I （55.6%）. All the hamartomas that detected by color fundus photography or IFG can be detected by OCT. Conclusion： Among the methods of color fundus photography, IFG, and OCT, the OCT has higher detection rate for retinal hamartoma in TSC patients; therefore, OCT might be promising for the clinical diagnosis of TSC.
基金financially supported by the National MCF Energy R&D Program (No. 2018YFE0312400)National Key Research and Development Program of China (No. 2019YFA0209901)+2 种基金National Natural Science Foundation of China (Nos. 51822402 and 51671044)Fundamental Research Funds for the Central Universities (No. DUT16ZD206)LiaoNing Revitalization Talents Program (No. XLYC1807047)。
文摘The emergence of eutectic high-entropy alloys(EHEAs)offers new insights into the design of next generation structural alloys,which is due to their stable dual-phase microstructure and outstanding mechanical properties from room to elevated temperatures.In this work,a series of(CoFe2 NiV0.5Mo0.2)100-xNbx(0≤x≤12)EHEAs were designed and prepared via vacuum arc-melting.Typical eutectic microstructure composing lamellar face-centered cubic solid solution phase and C14 Laves phase appears in the as-cast EHEA when x=9.The microstructure turns to hypoeutectic or hypereutectic when x is below or beyond that critical value accordingly.The volume fraction of the hard Laves phase is proportional to the Nb addition,leading to the strength increment yet at the expense of ductility at room temperature.In particular,the EHEA having4 at%Nb shows a compressive strength of 2.1 GPa with an elongation to fracture of 45%,while EHEAs containing 9 and10 at%Nb exhibit ultrahigh yield strengths of over 1.4 GPa.The effect of Nb addition on the corrosion resistance of this Crfree EHEA system was also studied.The EHEA containing 9 at%Nb has the best anti-corrosion performance in the 3.5 wt%NaCl solution at 298±1 K,indicating a good combination of mechanical and corrosion properties.
基金Project supported by the National Natural Science Foundation of China(Grant No.61991441)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB33000000).
文摘The optical absorption is the most important macroscopic process to characterize the microscopic optical transition in the semiconductor materials. Recently, great enhancement has been observed in the absorption of the active region within a p–n junction. In this paper, Ga As based p–i–n samples with the active region varied from 100 nm to 3 μm were fabricated and it was observed that the external quantum efficiencies are higher than the typical results, indicating a new mechanism beyond the established theories. We proposed a theoretical model about the abnormal optical absorption process in the active region within a strong electric field, which might provide new theories for the design of the solar cells,photodetectors, and other photoelectric devices.
基金financially supported by the National Key R&D Program of China(No.2017YFB0102004)the National Natural Science Foundation of China(Nos.51822211,U1932220,U1964205,and Y5JC011E21)。
文摘The employment of lithium metal anode in rechargeable lithium batteries has been hindered by the safety concerns which are associated with the uncontrolled lithium dendrite growth and the unceasing side reactions with liquid electrolytes.In this work,we report that the use of Ti-containing solid electrolyte-coated separators can greatly enhance the cycle performances of lithium metal anode in cells using liquid electrolytes.The detailed morphologic studies indicate that more uniform lithium deposition is achieved in cells using Ti-containing solid electrolyte-coated separators than that using Al_(2)O_(3)-coated separators,which is likely due to the modified anode and electrolyte interfacial properties induced by the reactive nature of Ti-containing solid electrolytes with metallic lithium.This work demonstrates an effective strategy to enhance the homogeneity of lithium deposition,which leads to the stable cycling of lithium metal anode in rechargeable lithium-ion batteries.
基金Projects(61572525,61272148)supported by the National Natural Science Foundation of ChinaProject(20120162110061)supported by the PhD Programs Foundation of Ministry of Education of China+1 种基金Project(CX2014B066)supported by the Hunan Provincial Innovation Foundation for Postgraduate,ChinaProject(2014zzts044)supported by the Fundamental Research Funds for the Central Universities,China
文摘Cloud data centers consume a multitude of power leading to the problem of high energy consumption. In order to solve this problem, an energy-efficient virtual machine(VM) consolidation algorithm named PVDE(prediction-based VM deployment algorithm for energy efficiency) is presented. The proposed algorithm uses linear weighted method to predict the load of a host and classifies the hosts in the data center, based on the predicted host load, into four classes for the purpose of VMs migration. We also propose four types of VM selection algorithms for the purpose of determining potential VMs to be migrated. We performed extensive performance analysis of the proposed algorithms. Experimental results show that, in contrast to other energy-saving algorithms, the algorithm proposed in this work significantly reduces the energy consumption and maintains low service level agreement(SLA) violations.
基金financially supported by the National Natural Science Foundation of China(No.51601011)the Fundamental Research Funds for the Central Universities+2 种基金the Recruitment Program of Global Expertsthe State Grid Scientific and Technological Research Program of China(No.5211DS17001X)the Zhejiang Electric Power Corporation Scientific and Technological Research Program of China(No.5211DS5002 M).
文摘The fracture of pipelines caused by corrosion cracks and the resulting oil and gas leakage can lead to great environmentalpollution and economic losses. These negative effects are due to serious corrosion of the plain carbon steels used for armorof flexible pipe in oil and gas transmission medium. However, corrosion resistance of carbon steel armors has yet to beimproved. In this study, the relationship between corrosion resistance and pearlite fraction in the plain carbon steels hasbeen investigated through the application of pulsed electric current. Based on immersion test and electrochemical mea-surement, pulsed electric current increases the corrosion resistance of the plain carbon steels by reducing the fraction ofpearlite phase. Pitting corrosion, which tends to initiate by galvanic corrosion of ferrite and cementite, is therefore inhibiteddue to the decrease in pearlite fraction （mixture of ferrite and cementite） under electropulsing.
