With the increasing number of wind farms in power systems, the scheduling of a single wind farm needs to be improved. For this end, this paper proposes an optimal short-term load dispatch strategy for a single wind fa...With the increasing number of wind farms in power systems, the scheduling of a single wind farm needs to be improved. For this end, this paper proposes an optimal short-term load dispatch strategy for a single wind farm. Firstly, considering the large number of wind units and the high dimensionality of the scheduling solutions, we analyze the unit load characteristics, from which we extract the unit load characteristic matrix, and then classify the wind power units with the FCM fuzzy clustering algorithm. Secondly, we define the running loss indicator and action loss indicator. Based on the prediction of wind power and the load instructions, we establish a unit commitment model in wind farm, and solve the model using a combination of the fuzzy clustering algorithm and genetic algorithm, which overcomes the difficulty of the high dimensionality of the solution in the wind farm scheduling problem, to obtain the optimal scheduling strategy. Finally, through the simulation of the scheduling strategy for a 45 MW wind farm, we demonstrate the feasibility and effectiveness of the proposed strategy.展开更多
This investigation aimed to unveil new prospective diagnosis-related biomarkers together with treatment targets against glioblastoma.Methods:The expression levels of long non-coding RNA(lncRNA)DPP10-AS1 were assessed ...This investigation aimed to unveil new prospective diagnosis-related biomarkers together with treatment targets against glioblastoma.Methods:The expression levels of long non-coding RNA(lncRNA)DPP10-AS1 were assessed using real-time quantitative polymerase chain reaction(RT-qPCR)within both the patient tissue specimens and glioblastoma cell lines.The relationship between lncRNA DPP10-AS1 expression in glioblastoma and patient prognosis was investigated.Cell Counting Kit-8(CCK-8),transwell,and clonogenic experiments were utilized to assess tumor cells’proliferation,invasiveness,and migratory potentials after lncRNA DPP10-AS1 expression was up or down-regulated.Using an online bioinformatics prediction tool,the intracellular localization of lncRNA DPP10-AS1 and its target miRNA were predicted,and RNA-FISH verified results.A dual-luciferase reporter experiment validated the relationship across miR-24-3p together with lncRNA DPP10-AS1.MiR-24-3p expression within glioblastoma was identified through RT-qPCR,and potential link across miR-24-3p and lncRNA DPP10-AS1 was assessed using Pearson correlation analysis.Moreover,influence from lncRNA DPP10-AS1/miR-24-3p axis upon glioblastoma cell progression was assessed in vivo via a subcutaneous xenograft tumor model.Results:The expression of lncRNA DPP10-AS1 was notably reduced in both surgical specimens of glioblastoma and the equivalent cell lines.Low level of lncRNA DPP10-AS1 in glioblastoma is following poor prognosis.The downregulation of lncRNA DPP10-AS1 in glioblastoma cells resulted in enhanced cellular proliferation,migration,and invasion capabilities,accompanied by downregulated E-cadherin and upregulated vimentin and N-cadherin.Additionally,the observed upregulation of lncRNA DPP10-AS1 demonstrated a substantial inhibitory function upon proliferation,invasion,and migratory capabilities of LN229 cells.Subcellular localization disclosed that lncRNA DPP10-AS1 had a binding site that interacted with miR-24-3p.Upregulated miR-24-3p was detected in glioblastomas,displ展开更多
Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to e...Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control performance.While the nonlinear characteristic of the tire model leads to a relatively heavier computational burden.To facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)model.Then a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort requirements.The in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy consumption.Finally,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)test.The results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability.展开更多
目的分析基底节区高血压脑出血术后早期经皮扩张气管切开的疗效。方法纳入2019年8月—2021年7月蚌埠医学院第一附属医院神经外科收治的108例基底节区高血压脑出血术后行气管切开患者,2d内气管切开为研究组60例和2天后气管切开为对照组48...目的分析基底节区高血压脑出血术后早期经皮扩张气管切开的疗效。方法纳入2019年8月—2021年7月蚌埠医学院第一附属医院神经外科收治的108例基底节区高血压脑出血术后行气管切开患者,2d内气管切开为研究组60例和2天后气管切开为对照组48例,分析气管切开后两组患者血氧饱和度、呼吸机脱机时间、肺部感染情况、气管切开前后格拉斯哥昏迷指数(Glasgow Coma Scale,GCS)评分和神经外科重症监护病房(Neurosurgical Itensive Care Unit,NICU)治疗时间。结果气管切开后两组患者血氧饱和度均有所改善,且研究组血氧饱和度(98.57±1.13)%比对照组血氧饱和度(96.25±1.23)%改善程度高,差异均有统计学意义(P<0.001)。应用呼吸机患者,研究组脱离呼吸机时间比对照组更早,差异有统计学意义(P<0.05)。术后肺部感染研究组21例(35.00%),对照组26例(54.17%),肺部感染率研究组更低,且感染控制时间研究组(8.75±1.60)d也少于对照组(13.50±2.21)d,差异均有统计学意义(P<0.05);感染类型在两组肺部感染患者中比较差异无统计学意义(P>0.05)。气管切开后14d两组患者GCS评分均增高,且研究组(10.58±2.12)分比对照组(9.44±1.18)分评分值要高,差异有统计学意义(P<0.001)。患者NICU治疗时间研究组(8.18±2.12)d短于对照组(10.46±2.49)d,差异有统计学意义(P<0.001)。结论早期气管切开能改善基底节区高血压脑出血患者术后血氧饱和度,使其尽早脱机,减少肺部感染率和肺部控制时间,帮助患者神经功能恢复,缩短NICU治疗时间。展开更多
To achieve the utilization of the abandoned ultrafine ilmenite(-20 μm) produced in the titanium magnetite processing plant in Panzhihua,the superconducting high-gradient magnetic separation(SMS) technology was propos...To achieve the utilization of the abandoned ultrafine ilmenite(-20 μm) produced in the titanium magnetite processing plant in Panzhihua,the superconducting high-gradient magnetic separation(SMS) technology was proposed in this study.After optimizing the conditions of magnetic intensity,feeding and pulsation,an SMS concentrate with TiO_(2) grade of 16.03% and TiO_(2) recovery of 66.39% was obtained through one roughing-one cleaning pre-concentration flowsheet.The specific magnetic force and magnetic force were calculated and analysed to illustrate the pre-concentration mechanism,and the results revealed that the combination of high magnetic field and strong pulsating resulted in the effective preconcentration of the ultrafine ilmenite in the SMS process.In addition,the magnetic force analysis indicated that the high magnetic intensity and high magnetic gradient are the key factors of the SMS technology.Furthermore,the EDS-Mapping detection certified that the ultrafine ilmenite was concentrated from the gangue minerals using SMS technology.展开更多
Among energy storage devices,electrochemical capacitors(ECs)possessing ultrahigh power density and long-term stability have attracted numerous research interests and thus enriched our arsenal when coping with specific...Among energy storage devices,electrochemical capacitors(ECs)possessing ultrahigh power density and long-term stability have attracted numerous research interests and thus enriched our arsenal when coping with specific issues[1-10].While a large number of aqueous ECs could run well at room temperature,demand for their survival and operation under thermal extremes is rising.For example,military-grade electrochemical energy storage(EES)devices are expected to operate from-40 to 60℃ and equipment for cold climates or high altitudes can experience temperatures as low as—60℃[11].展开更多
基金supported by the National Basic Research Program of China ("973" Project) (Grant No. 2012CB215203)the National Natural Science Major Fund Project (Grant No. 51036002)
文摘With the increasing number of wind farms in power systems, the scheduling of a single wind farm needs to be improved. For this end, this paper proposes an optimal short-term load dispatch strategy for a single wind farm. Firstly, considering the large number of wind units and the high dimensionality of the scheduling solutions, we analyze the unit load characteristics, from which we extract the unit load characteristic matrix, and then classify the wind power units with the FCM fuzzy clustering algorithm. Secondly, we define the running loss indicator and action loss indicator. Based on the prediction of wind power and the load instructions, we establish a unit commitment model in wind farm, and solve the model using a combination of the fuzzy clustering algorithm and genetic algorithm, which overcomes the difficulty of the high dimensionality of the solution in the wind farm scheduling problem, to obtain the optimal scheduling strategy. Finally, through the simulation of the scheduling strategy for a 45 MW wind farm, we demonstrate the feasibility and effectiveness of the proposed strategy.
基金supported through the Natural Science Foundation of Jiangsu Province(No.BK20201172)the Key Project of the Jiangsu Health Commission(No.ZDB2020016)the Jiangsu Province Key Research and Development Program:Social Development Project(No.BE2021653).
文摘This investigation aimed to unveil new prospective diagnosis-related biomarkers together with treatment targets against glioblastoma.Methods:The expression levels of long non-coding RNA(lncRNA)DPP10-AS1 were assessed using real-time quantitative polymerase chain reaction(RT-qPCR)within both the patient tissue specimens and glioblastoma cell lines.The relationship between lncRNA DPP10-AS1 expression in glioblastoma and patient prognosis was investigated.Cell Counting Kit-8(CCK-8),transwell,and clonogenic experiments were utilized to assess tumor cells’proliferation,invasiveness,and migratory potentials after lncRNA DPP10-AS1 expression was up or down-regulated.Using an online bioinformatics prediction tool,the intracellular localization of lncRNA DPP10-AS1 and its target miRNA were predicted,and RNA-FISH verified results.A dual-luciferase reporter experiment validated the relationship across miR-24-3p together with lncRNA DPP10-AS1.MiR-24-3p expression within glioblastoma was identified through RT-qPCR,and potential link across miR-24-3p and lncRNA DPP10-AS1 was assessed using Pearson correlation analysis.Moreover,influence from lncRNA DPP10-AS1/miR-24-3p axis upon glioblastoma cell progression was assessed in vivo via a subcutaneous xenograft tumor model.Results:The expression of lncRNA DPP10-AS1 was notably reduced in both surgical specimens of glioblastoma and the equivalent cell lines.Low level of lncRNA DPP10-AS1 in glioblastoma is following poor prognosis.The downregulation of lncRNA DPP10-AS1 in glioblastoma cells resulted in enhanced cellular proliferation,migration,and invasion capabilities,accompanied by downregulated E-cadherin and upregulated vimentin and N-cadherin.Additionally,the observed upregulation of lncRNA DPP10-AS1 demonstrated a substantial inhibitory function upon proliferation,invasion,and migratory capabilities of LN229 cells.Subcellular localization disclosed that lncRNA DPP10-AS1 had a binding site that interacted with miR-24-3p.Upregulated miR-24-3p was detected in glioblastomas,displ
基金Supported by National Natural Science Foundation of China(Grant Nos.51975118,52025121)Foundation of State Key Laboratory of Automotive Simulation and Control of China(Grant No.20210104)+1 种基金Foundation of State Key Laboratory of Automobile Safety and Energy Saving of China(Grant No.KFZ2201)Special Fund of Jiangsu Province for the Transformation of Scientific and Technological Achievements of China(Grant No.BA2021023).
文摘Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control performance.While the nonlinear characteristic of the tire model leads to a relatively heavier computational burden.To facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)model.Then a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort requirements.The in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy consumption.Finally,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)test.The results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability.
文摘目的分析基底节区高血压脑出血术后早期经皮扩张气管切开的疗效。方法纳入2019年8月—2021年7月蚌埠医学院第一附属医院神经外科收治的108例基底节区高血压脑出血术后行气管切开患者,2d内气管切开为研究组60例和2天后气管切开为对照组48例,分析气管切开后两组患者血氧饱和度、呼吸机脱机时间、肺部感染情况、气管切开前后格拉斯哥昏迷指数(Glasgow Coma Scale,GCS)评分和神经外科重症监护病房(Neurosurgical Itensive Care Unit,NICU)治疗时间。结果气管切开后两组患者血氧饱和度均有所改善,且研究组血氧饱和度(98.57±1.13)%比对照组血氧饱和度(96.25±1.23)%改善程度高,差异均有统计学意义(P<0.001)。应用呼吸机患者,研究组脱离呼吸机时间比对照组更早,差异有统计学意义(P<0.05)。术后肺部感染研究组21例(35.00%),对照组26例(54.17%),肺部感染率研究组更低,且感染控制时间研究组(8.75±1.60)d也少于对照组(13.50±2.21)d,差异均有统计学意义(P<0.05);感染类型在两组肺部感染患者中比较差异无统计学意义(P>0.05)。气管切开后14d两组患者GCS评分均增高,且研究组(10.58±2.12)分比对照组(9.44±1.18)分评分值要高,差异有统计学意义(P<0.001)。患者NICU治疗时间研究组(8.18±2.12)d短于对照组(10.46±2.49)d,差异有统计学意义(P<0.001)。结论早期气管切开能改善基底节区高血压脑出血患者术后血氧饱和度,使其尽早脱机,减少肺部感染率和肺部控制时间,帮助患者神经功能恢复,缩短NICU治疗时间。
基金financial support from the Joint Fund (Key program U2067201) for Nuclear Technology Innovation Sponsored by the National Natural Science Foundation of China and the China National Nuclear CorporationNational key research and development program (2019YFC1907702) Sponsored by MOSTthe Fundamental Research Funds for the Central Universities (N2001013) for supporting this research。
文摘To achieve the utilization of the abandoned ultrafine ilmenite(-20 μm) produced in the titanium magnetite processing plant in Panzhihua,the superconducting high-gradient magnetic separation(SMS) technology was proposed in this study.After optimizing the conditions of magnetic intensity,feeding and pulsation,an SMS concentrate with TiO_(2) grade of 16.03% and TiO_(2) recovery of 66.39% was obtained through one roughing-one cleaning pre-concentration flowsheet.The specific magnetic force and magnetic force were calculated and analysed to illustrate the pre-concentration mechanism,and the results revealed that the combination of high magnetic field and strong pulsating resulted in the effective preconcentration of the ultrafine ilmenite in the SMS process.In addition,the magnetic force analysis indicated that the high magnetic intensity and high magnetic gradient are the key factors of the SMS technology.Furthermore,the EDS-Mapping detection certified that the ultrafine ilmenite was concentrated from the gangue minerals using SMS technology.
基金financially supported by the Basic Research Project of Science and Technology Innovation Commission of Shenzhen (JCYJ20170817110251498)Guangdong Special Support for Science and Technology Leading Young Scientist (2016TQ03C919)the National Natural Science Foundation of China (21603094, 21703096, and 11775105)
文摘Among energy storage devices,electrochemical capacitors(ECs)possessing ultrahigh power density and long-term stability have attracted numerous research interests and thus enriched our arsenal when coping with specific issues[1-10].While a large number of aqueous ECs could run well at room temperature,demand for their survival and operation under thermal extremes is rising.For example,military-grade electrochemical energy storage(EES)devices are expected to operate from-40 to 60℃ and equipment for cold climates or high altitudes can experience temperatures as low as—60℃[11].
