In recent years, studies have demonstrated that biophoton is a medium for the transmission and processing of neural information. However, such studies were mainly carried out by using brain slices combined with biopho...In recent years, studies have demonstrated that biophoton is a medium for the transmission and processing of neural information. However, such studies were mainly carried out by using brain slices combined with biophoton imaging technology, while there are few reports on <i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> brain biophoton imaging. In this study, the ultraweak biophoton imaging system (UBIS) was employed to carry out an </span><i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> biophoton imaging for the whole brain of mice. It was found that the biophoton emission of whole brain in the slight</span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ly</span></span></span></span><span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> anesthetized mice was significantly higher than that of the background, suggesting that the brain of living mouse emits a certain intensity of stable biophotons. The biophoton imaging established in this study for the </span><i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> mouse whole brain may provide a new technical method for further study of the relationship between the biophoton and brain functions, and give new ideas for developing diagnostic method of neuropsychiatric diseases.</span></span></span></span></span>展开更多
Rheumatoid arthritis (RA) is a common form of chronic inflammatory arthritis, and it mainly causes the destruction of small joints. The development of this disease is a relatively secret and repeated process, and ther...Rheumatoid arthritis (RA) is a common form of chronic inflammatory arthritis, and it mainly causes the destruction of small joints. The development of this disease is a relatively secret and repeated process, and therefore early diagnosis and evaluation of the disease is usually difficult. In this study, an arthritis model was successfully induced by injecting complete Freund’s adjuvant (CFA) into the toes of lower limbs of Wistar rats. Seven days after injection of CFA, obvious redness and swelling appeared at the toe joints of lower limbs accompanied by more sensitivity to thermal stimulation. Using the ultraweak bio-photon imaging system (UBIS) established by us, the toe joint area of the lower limbs of rats was imaged 7 days after injection of CFA. It was found that the volar part of lower limbs of arthritis rats showed significantly higher biophoton emissions compared with the control group. The results of this study may provide a basis for further research and devel-opment of early diagnosis and assessment of lesion progression of rheumatoid arthritis.展开更多
文摘In recent years, studies have demonstrated that biophoton is a medium for the transmission and processing of neural information. However, such studies were mainly carried out by using brain slices combined with biophoton imaging technology, while there are few reports on <i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> brain biophoton imaging. In this study, the ultraweak biophoton imaging system (UBIS) was employed to carry out an </span><i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> biophoton imaging for the whole brain of mice. It was found that the biophoton emission of whole brain in the slight</span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ly</span></span></span></span><span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> anesthetized mice was significantly higher than that of the background, suggesting that the brain of living mouse emits a certain intensity of stable biophotons. The biophoton imaging established in this study for the </span><i><span style="font-family:Verdana;">in</span></i><span style="font-family:Verdana;"> <i>vivo</i></span><span style="font-family:Verdana;"> mouse whole brain may provide a new technical method for further study of the relationship between the biophoton and brain functions, and give new ideas for developing diagnostic method of neuropsychiatric diseases.</span></span></span></span></span>
文摘Rheumatoid arthritis (RA) is a common form of chronic inflammatory arthritis, and it mainly causes the destruction of small joints. The development of this disease is a relatively secret and repeated process, and therefore early diagnosis and evaluation of the disease is usually difficult. In this study, an arthritis model was successfully induced by injecting complete Freund’s adjuvant (CFA) into the toes of lower limbs of Wistar rats. Seven days after injection of CFA, obvious redness and swelling appeared at the toe joints of lower limbs accompanied by more sensitivity to thermal stimulation. Using the ultraweak bio-photon imaging system (UBIS) established by us, the toe joint area of the lower limbs of rats was imaged 7 days after injection of CFA. It was found that the volar part of lower limbs of arthritis rats showed significantly higher biophoton emissions compared with the control group. The results of this study may provide a basis for further research and devel-opment of early diagnosis and assessment of lesion progression of rheumatoid arthritis.