To the Editor:Schwannoma is an infrequent tumor originating from Schwann cells of the peripheral nerve sheath and was first reported as a true neoplasm originating from Schwann cells in 1910 [1] . The ma- jority of sc...To the Editor:Schwannoma is an infrequent tumor originating from Schwann cells of the peripheral nerve sheath and was first reported as a true neoplasm originating from Schwann cells in 1910 [1] . The ma- jority of schwannomas are detected as a solitary tumor from the peripheral nerves of the face, neck, trunk, extremities, or retroperi- toneal region. Based on a previous study [2] , merely 3% of schwan- nomas are retroperitoneal, accounting for approximately 4% of all retroperitoneal tumors. Furthermore, pancreatic schwannomas that stem from either parasympathetic or sympathetic fibers of the pancreas are especially rare. Schwannomas are generally encapsu- lated, and over 90% are benign [3] . Considering its benign biolog- ical behavior, it is essential to accurately diagnose schwannomas in order to apply reasonable surgical methods and postoperative surveillance. Herein, we report four cases of pancreatic schwan- noma in our center to update the data on the clinicopathological traits about this type of tumor.展开更多
Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,b...Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,but the pathogenesis is largely unknown.A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation,but NAFPD remains an under-recognized and non-independent disorder.Obesity,age,sex,race,and unhealthy lifestyle are established independent risk factors for NAFPD,which is strongly associated with metabolic syndrome,type 2 diabetes,pancreatitis,pancreatic fistula,pancreatic cancer,and nonalcoholic fatty liver disease.At present,imaging techniques are common diagnostic aids,but uniform criteria and consensus are lacking.Therapeutically,healthy diet,weight loss,and exercise are the mainstays to reduce pancreatic fat accumulation.It can be seen that there is a limited understanding of NAFPD at this stage and further exploration is needed.Previous studies have revealed that NAFPD may directly affect diagnosis and clinical decision-making.Therefore,exploring the pathophysiological mechanism and clinical associations of NAFPD is a major challenge for researchers and clinicians.展开更多
目的探讨更年期门诊妇女绝经综合征与抑郁症状的相关性。方法将2016年7月—2017年2月期间因围绝经期相关症状在中国福利会国际和平妇幼保健院更年期门诊首次就诊的妇女纳入本研究。调查研究对象的一般情况、健康状况,应用Kupperman绝经...目的探讨更年期门诊妇女绝经综合征与抑郁症状的相关性。方法将2016年7月—2017年2月期间因围绝经期相关症状在中国福利会国际和平妇幼保健院更年期门诊首次就诊的妇女纳入本研究。调查研究对象的一般情况、健康状况,应用Kupperman绝经指数量表(Kupperman menopausal index,KMI)评估围绝经期相关症状,采用患者健康问卷抑郁量表(patient health questionnaire,PHQ-9)对抑郁症状进行量化评分。结果共计调查153名门诊妇女,平均年龄为(47.3±4.3)岁,月经不规则者占77.78%。73.86%的调查对象患有绝经综合征(KMI>6),疲乏(70.59%)、情绪波动(63.40%)、失眠(59.48%)、潮热出汗(56.21%)和骨关节痛(52.29%)是最常见的围绝经期症状;35.95%的门诊妇女存在抑郁症状(PHQ-9≥5)。绝经综合征的严重程度、相关症状的共患程度与门诊妇女是否患有抑郁症状显著相关。多因素分析显示,抑郁症与潮热出汗、失眠、情绪波动、眩晕、疲乏、头痛、心悸、性生活等具体症状的严重程度均有统计学联系。结论更年期门诊患者绝经综合征和抑郁症状间存在明显联系。未来应加强对围绝经期妇女心理健康问题的关注,使更多的妇女平稳度过围绝经期。展开更多
基金supported by a grant from the Youth Start-up Fund Project of Changhai Hospital(CH201823).
文摘To the Editor:Schwannoma is an infrequent tumor originating from Schwann cells of the peripheral nerve sheath and was first reported as a true neoplasm originating from Schwann cells in 1910 [1] . The ma- jority of schwannomas are detected as a solitary tumor from the peripheral nerves of the face, neck, trunk, extremities, or retroperi- toneal region. Based on a previous study [2] , merely 3% of schwan- nomas are retroperitoneal, accounting for approximately 4% of all retroperitoneal tumors. Furthermore, pancreatic schwannomas that stem from either parasympathetic or sympathetic fibers of the pancreas are especially rare. Schwannomas are generally encapsu- lated, and over 90% are benign [3] . Considering its benign biolog- ical behavior, it is essential to accurately diagnose schwannomas in order to apply reasonable surgical methods and postoperative surveillance. Herein, we report four cases of pancreatic schwan- noma in our center to update the data on the clinicopathological traits about this type of tumor.
文摘Nonalcoholic fatty pancreas disease(NAFPD)is an emerging disease that has gained an increasing amount of attention in recent years.It describes fat accumulation in the pancreas with insignificant alcohol consumption,but the pathogenesis is largely unknown.A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation,but NAFPD remains an under-recognized and non-independent disorder.Obesity,age,sex,race,and unhealthy lifestyle are established independent risk factors for NAFPD,which is strongly associated with metabolic syndrome,type 2 diabetes,pancreatitis,pancreatic fistula,pancreatic cancer,and nonalcoholic fatty liver disease.At present,imaging techniques are common diagnostic aids,but uniform criteria and consensus are lacking.Therapeutically,healthy diet,weight loss,and exercise are the mainstays to reduce pancreatic fat accumulation.It can be seen that there is a limited understanding of NAFPD at this stage and further exploration is needed.Previous studies have revealed that NAFPD may directly affect diagnosis and clinical decision-making.Therefore,exploring the pathophysiological mechanism and clinical associations of NAFPD is a major challenge for researchers and clinicians.
文摘目的探讨更年期门诊妇女绝经综合征与抑郁症状的相关性。方法将2016年7月—2017年2月期间因围绝经期相关症状在中国福利会国际和平妇幼保健院更年期门诊首次就诊的妇女纳入本研究。调查研究对象的一般情况、健康状况,应用Kupperman绝经指数量表(Kupperman menopausal index,KMI)评估围绝经期相关症状,采用患者健康问卷抑郁量表(patient health questionnaire,PHQ-9)对抑郁症状进行量化评分。结果共计调查153名门诊妇女,平均年龄为(47.3±4.3)岁,月经不规则者占77.78%。73.86%的调查对象患有绝经综合征(KMI>6),疲乏(70.59%)、情绪波动(63.40%)、失眠(59.48%)、潮热出汗(56.21%)和骨关节痛(52.29%)是最常见的围绝经期症状;35.95%的门诊妇女存在抑郁症状(PHQ-9≥5)。绝经综合征的严重程度、相关症状的共患程度与门诊妇女是否患有抑郁症状显著相关。多因素分析显示,抑郁症与潮热出汗、失眠、情绪波动、眩晕、疲乏、头痛、心悸、性生活等具体症状的严重程度均有统计学联系。结论更年期门诊患者绝经综合征和抑郁症状间存在明显联系。未来应加强对围绝经期妇女心理健康问题的关注,使更多的妇女平稳度过围绝经期。
