CNN(convolutional neural network)based real time trackers usually do not carry out online network update in order to maintain rapid tracking speed.This inevitably influences the adaptability to changes in object appea...CNN(convolutional neural network)based real time trackers usually do not carry out online network update in order to maintain rapid tracking speed.This inevitably influences the adaptability to changes in object appearance.Correlation filter based trackers can update the model parameters online in real time.In this paper,we present an end-to-end lightweight network architecture,namely Discriminant Correlation Filter Network(DCFNet).A differentiable DCF(discriminant correlation filter)layer is incorporated into a Siamese network architecture in order to learn the convolutional features and the correlation filter simultaneously.The correlation filter can be efficiently updated online.In previous work,we introduced a joint scale-position space to the DCFNet,forming a scale DCFNet which carries out the predictions of object scale and position simultaneously.We combine the scale DCFNet with the convolutional-deconvolutional network,learning both the high-level embedding space representations and the low-level fine-grained representations for images.The adaptability of the fine-grained correlation analysis and the generalization capability of the semantic embedding are complementary for visual tracking.The back-propagation is derived in the Fourier frequency domain throughout the entire work,preserving the efficiency of the DCF.Extensive evaluations on the OTB(Object Tracking Benchmark)and VOT(Visual Object Tracking Challenge)datasets demonstrate that the proposed trackers have fast speeds,while maintaining tracking accuracy.展开更多
当今医学研究透明化概念备受关注。通过研究注册,向社会公开研究方案的概况及具体信息,可提高研究质量和透明度。当前可进行指南注册的机构主要为国际实践指南注册与透明化平台(Practice Guideline REgistration for TransPAREncy,PREPA...当今医学研究透明化概念备受关注。通过研究注册,向社会公开研究方案的概况及具体信息,可提高研究质量和透明度。当前可进行指南注册的机构主要为国际实践指南注册与透明化平台(Practice Guideline REgistration for TransPAREncy,PREPARE);系统评价/Meta分析注册机构主要有Cochrane协作网、PROSPERO(International Prospective Register of Systematic Reviews,PROSPERO)国际化注册平台、JBI(Joanna Briggs Institute,JBI)循证卫生保健中心、Campbell协作网、环境证据协作网(The Collaboration for Environmental Evidence,CEE)以及最新启动使用的INPLASY(International Platform of Registered Systematic Review and Meta-analysis Protocols,INPLASY)注册平台。本文介绍了上述各平台的基本信息,以及不同系统评价/Meta分析注册平台之间的异同,为相关科研工作者提供参考。展开更多
目的探讨二甲双胍对老年2型糖尿病患者肠道菌群、血糖血脂及炎性因子水平的影响。方法选取2018年3月至2019年9月我院收治的120例2型糖尿病患者为研究对象,随机分为观察组和对照组,各60例。两组患者均给予常规胰岛素治疗,观察组在此基础...目的探讨二甲双胍对老年2型糖尿病患者肠道菌群、血糖血脂及炎性因子水平的影响。方法选取2018年3月至2019年9月我院收治的120例2型糖尿病患者为研究对象,随机分为观察组和对照组,各60例。两组患者均给予常规胰岛素治疗,观察组在此基础上加用二甲双胍治疗。观察两组患者治疗前后肠道菌群变化,胰岛功能水平[空腹胰岛素(FINS)、餐后2 h胰岛素(2hINS)、空腹C肽(FCP)、餐后2 h C肽(2hCP)、胰岛素抵抗指数(HOMA-IR)],血糖血脂水平[糖化血红蛋白(HbAlc)、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]及炎性因子水平[白细胞介素6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)]。结果治疗前,两组患者肠道菌群数量比较差异无统计学意义(均P>0.05)。治疗后,对照组患者肠道菌群数量与治疗前比较差异无统计学意义(均P>0.05),而观察组患者肠道双歧杆菌、乳杆菌、拟杆菌数量较治疗前和对照组均显著增加,肠球菌、肠杆菌及酵母菌数量显著降低(均P<0.05)。治疗前,两组患者胰岛功能水平、血糖血脂水平及炎性因子水平比较差异均无统计学意义(均P>0.05)。治疗后,两组患者FINS、2hINS、FCP、2hCP水平明显升高,且观察组高于对照组(均P<0.05);HOMA-IR、HbAlc、FPG、TG、LDL-C、CRP、IL-6和TNF-α水平显著降低,且观察组低于对照组(均P<0.05)。结论二甲双胍可明显增加患者肠道有益菌群数量,调节菌群失衡,控制血糖血脂代谢水平,改善炎症状态。展开更多
基金supported by the National Key Research and Development Program of China under Grant Nos.2020AAA0105802 and 2020AAA0105800the National Natural Science Foundation of China under Grant Nos.62036011,62192782,61721004,and U2033210the Beijing Natural Science Foundation under Grant No.L223003.
文摘CNN(convolutional neural network)based real time trackers usually do not carry out online network update in order to maintain rapid tracking speed.This inevitably influences the adaptability to changes in object appearance.Correlation filter based trackers can update the model parameters online in real time.In this paper,we present an end-to-end lightweight network architecture,namely Discriminant Correlation Filter Network(DCFNet).A differentiable DCF(discriminant correlation filter)layer is incorporated into a Siamese network architecture in order to learn the convolutional features and the correlation filter simultaneously.The correlation filter can be efficiently updated online.In previous work,we introduced a joint scale-position space to the DCFNet,forming a scale DCFNet which carries out the predictions of object scale and position simultaneously.We combine the scale DCFNet with the convolutional-deconvolutional network,learning both the high-level embedding space representations and the low-level fine-grained representations for images.The adaptability of the fine-grained correlation analysis and the generalization capability of the semantic embedding are complementary for visual tracking.The back-propagation is derived in the Fourier frequency domain throughout the entire work,preserving the efficiency of the DCF.Extensive evaluations on the OTB(Object Tracking Benchmark)and VOT(Visual Object Tracking Challenge)datasets demonstrate that the proposed trackers have fast speeds,while maintaining tracking accuracy.
文摘当今医学研究透明化概念备受关注。通过研究注册,向社会公开研究方案的概况及具体信息,可提高研究质量和透明度。当前可进行指南注册的机构主要为国际实践指南注册与透明化平台(Practice Guideline REgistration for TransPAREncy,PREPARE);系统评价/Meta分析注册机构主要有Cochrane协作网、PROSPERO(International Prospective Register of Systematic Reviews,PROSPERO)国际化注册平台、JBI(Joanna Briggs Institute,JBI)循证卫生保健中心、Campbell协作网、环境证据协作网(The Collaboration for Environmental Evidence,CEE)以及最新启动使用的INPLASY(International Platform of Registered Systematic Review and Meta-analysis Protocols,INPLASY)注册平台。本文介绍了上述各平台的基本信息,以及不同系统评价/Meta分析注册平台之间的异同,为相关科研工作者提供参考。
文摘目的探讨二甲双胍对老年2型糖尿病患者肠道菌群、血糖血脂及炎性因子水平的影响。方法选取2018年3月至2019年9月我院收治的120例2型糖尿病患者为研究对象,随机分为观察组和对照组,各60例。两组患者均给予常规胰岛素治疗,观察组在此基础上加用二甲双胍治疗。观察两组患者治疗前后肠道菌群变化,胰岛功能水平[空腹胰岛素(FINS)、餐后2 h胰岛素(2hINS)、空腹C肽(FCP)、餐后2 h C肽(2hCP)、胰岛素抵抗指数(HOMA-IR)],血糖血脂水平[糖化血红蛋白(HbAlc)、空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]及炎性因子水平[白细胞介素6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)]。结果治疗前,两组患者肠道菌群数量比较差异无统计学意义(均P>0.05)。治疗后,对照组患者肠道菌群数量与治疗前比较差异无统计学意义(均P>0.05),而观察组患者肠道双歧杆菌、乳杆菌、拟杆菌数量较治疗前和对照组均显著增加,肠球菌、肠杆菌及酵母菌数量显著降低(均P<0.05)。治疗前,两组患者胰岛功能水平、血糖血脂水平及炎性因子水平比较差异均无统计学意义(均P>0.05)。治疗后,两组患者FINS、2hINS、FCP、2hCP水平明显升高,且观察组高于对照组(均P<0.05);HOMA-IR、HbAlc、FPG、TG、LDL-C、CRP、IL-6和TNF-α水平显著降低,且观察组低于对照组(均P<0.05)。结论二甲双胍可明显增加患者肠道有益菌群数量,调节菌群失衡,控制血糖血脂代谢水平,改善炎症状态。