AIM: To establish a method to detect the expression of the tumor specific growth factor TSGF, CA242 and CA19-9 in serum and evaluate their value in diagnosis of pancreatic cancer. METHODS: ELISA and Biochemical colori...AIM: To establish a method to detect the expression of the tumor specific growth factor TSGF, CA242 and CA19-9 in serum and evaluate their value in diagnosis of pancreatic cancer. METHODS: ELISA and Biochemical colorimetric assay were used to detect the serum content of TSGF, CA242 and CA19-9 in 200 normal cases, 52 pancreatitis patients and 96 pancreatic cancer patients. RESULTS: The positive likelihood ratios of TSGF, CA242 and CA19-9 were 5.4, 12.6 and 6.3, respectively, and their negative likelihood ratios were 0.10, 0.19 and 0.17, respectively. With single tumor marker diagnosed pancreatic cancer, the highest sensitivity and specificity of TSGF were 91.6% and 93.5%. In combined test with 3 markers, when all of them were positive, the sensitivity changed to 77.0% and the specificity and the positive predictive value were 100%. The levels of TSGF and CA242 were significantly higher in the patients with pancreatic cancer of head than those in the patients with pancreatic cancer of body, tail and whole pancreas, but the expression of CA19-9 had no correlation with the positions of the pancreatic cancer. The sensitivity of TSGF, CA242 and CA19-9 was increased with the progress in stages of pancreatic cancer. In stage I, the sensitivity of TSGF was markedly higher than CA242 and CA19-9. CONCLUSION: The combined use of TSGF, CA242 and CA19-9 expressions can elevate the specificity for pancreatmc cancer diagnosis. And it shows that it plays an important role to differentiate positions and tissue typing. It is a forepart diagnosis for the pancreatic cancer by combination checking. There is very important correlation between the three markers and the pancreatic cancer.展开更多
Nonfullerene-based organic solar cells(NFOSCs)have received great interest recently due to their higher performance and greater potential compared with fullerene-based solar cells[1].Power conversion efficiencies(PCEs...Nonfullerene-based organic solar cells(NFOSCs)have received great interest recently due to their higher performance and greater potential compared with fullerene-based solar cells[1].Power conversion efficiencies(PCEs)over 13% have been realized in single-junction NFOSCs[2].Compared with traditional fullerene acceptors,the greatest advantage of nonfullerene acceptors is their stronger light-harvesting capability in the visible and展开更多
As a part of a basic research project on Xeno-transplantion. we have been engaged in the derivation of embryonic stein cell lines from Chinese mini swine. Here, we reported for the first time the establishment of two ...As a part of a basic research project on Xeno-transplantion. we have been engaged in the derivation of embryonic stein cell lines from Chinese mini swine. Here, we reported for the first time the establishment of two porcine EG cell lines (BPEG1 and BPEG2) from primordial germ cells of genital ridges of a 28 and a 27 d embryos respectively. Their pluripotent nature has been identified by colony morphology, marker characterization as well as by in vitro and in vivo differentiation. These porcine EG cells are potentially useful for further basic studies.展开更多
Severe damage to suspended ceilings of metal grids and lay-in panels was observed in public buildings during the 2013 M7.0 Lushan earthquake in China. Over the past several years, suspended ceilings have been widely u...Severe damage to suspended ceilings of metal grids and lay-in panels was observed in public buildings during the 2013 M7.0 Lushan earthquake in China. Over the past several years, suspended ceilings have been widely used practice in public buildings throughout China, including government offices, schools and hospitals. To investigate the damage mechanism of suspended ceilings, a series of three-dimensional shake table tests was conducted to reproduce the observed damage. A full-scale reinforced concrete frame was constructed as the testing frame for the ceiling, which was single-story and infilled with brick masonry walls to represent the local construction of low-rise buildings. In general, the ceiling in the tests exhibited similar damage phenomena as the field observations, such as higher vulnerability of perimeter elements and extensive damage to the cross runners. However, it exhibited lower fragility in terms of peak ground/roof accelerations at the initiation of damage. Further investigations are needed to clarify the reasons for this behavior.展开更多
Severe damage to steel space structures is rarely reported when compared to other structural systems damaged during past major earthquakes around the world. Two gymnasiums of steel space structures in downtown Lushan ...Severe damage to steel space structures is rarely reported when compared to other structural systems damaged during past major earthquakes around the world. Two gymnasiums of steel space structures in downtown Lushan County that were damaged during the 2013 M7.0 Lushan earthquake in China were investigated and the observations are summarized in this paper. Typical damage to these two steel space structures ranges from moderate to severe. Moderate damage includes global buckling and dislocation of bolted connections of truss members, and inelastic elongation of anchor bolts and sliding of pedestal plates of supports. Severe damage includes member fracture caused by local buckling, and fracture failure of anchor bolts and welds. The distribution of structural damage to these two structures is described in detail and future research opportunities are suggested.展开更多
Sedimentary sequences in the Subei Basin are complex and have been affected by interactions between the ocean and rivers since the Late Pliocene, including the Yellow River, Huaihe River, and the Yangtze River. This s...Sedimentary sequences in the Subei Basin are complex and have been affected by interactions between the ocean and rivers since the Late Pliocene, including the Yellow River, Huaihe River, and the Yangtze River. This sedimentary evolution, in particular the timing of Pleistocene transgressions, has long been a matter of controversy owing to the lack of precise chronological evidence. The aim of this study is to explore the evolution of the sedimentary environment throughout the past 3.00 Ma in this region on the basis of a comprehensive analysis of particle size and foraminifera and ostracods collected in the TZK9 core from the Subei Basin combined with geochronological studies of magnetostratigraphy, AMS^(14)C and optically stimulated luminescence(OSL). The results show that fluvial facies in the sedimentary environment from 3.00 to 1.01 Ma. There were fluvial facies and reflects six sea-level high stands from 1.01 to 0.25 Ma. The study area was affected by four large-scale transgressions since 0.25 Ma. The four marine sedimentary layers known as DU7(buried at 48–52 m), DU5(buried at 35–41 m), DU3(buried at 16–23 m), and DU1(buried at 2–4 m) are recorded in the MIS7(210–250 ka), MIS5, MIS3, and Holocene, respectively. The magnitude of the DU5 transgression was identical to that of the DU3 transgression, both were larger than the DU7 transgression, and the DU1 transgression was the weakest. The variation of transgression strength reflects the influence of global changes in sea level, tectonic subsidence, shell ridges, and sand dams. In the TZK9 core, we found evidence of seven sea-level high stands from the Early–Middle Pleistocene, and the first one caused by regional rapid subsidence and could be traced back to 0.83-0.84 Ma. The sea-level high stands and the age of the first one recorded above was different from other cores in eastern China, this was caused by the lack of absolute age control and the differences in paleotopography during this period. This study reconstructs sedimentary evolution, det展开更多
Porcelain electrical equipment （PEE）, such as current transformers, is critical to power supply systems, but its seismic performance during past earthquakes has not been satisfactory. This paper studies the seismic ...Porcelain electrical equipment （PEE）, such as current transformers, is critical to power supply systems, but its seismic performance during past earthquakes has not been satisfactory. This paper studies the seismic performance of two typical types of PEE and proposes a damping method for PEE based on multiple tuned mass dampers （MTMD）. An MTMD damping device involving three mass units, named a triple tuned mass damper （TTMD）, is designed and manufactured. Through shake table tests and finite element analysis, the dynamic characteristics of the PEE are studied and the effectiveness of the MTMD damping method is verified. The adverse influence of MTMD redundant mass to damping efficiency is studied and relevant equations are derived. MTMD robustness is verified through adjusting TTMD control frequencies. The damping effectiveness of TTMD, when the peak ground acceleration far exceeds the design value, is studied. Both shake table tests and finite element analysis indicate that MTMD is effective and robust in attenuating PEE seismic responses. TTMD remains effective when the PGA far exceeds the design value and when control deviations are considered.展开更多
AIM:To study the therapeutic effects of zhaoyangwan (ZYW) on chronic hepatitis B and hepatic cirrhosis and the anti-virus, anti-fibrosis and immunoregulatory mechanisms of ZYW.METHODS: Fifty cases of chronic hepatitis...AIM:To study the therapeutic effects of zhaoyangwan (ZYW) on chronic hepatitis B and hepatic cirrhosis and the anti-virus, anti-fibrosis and immunoregulatory mechanisms of ZYW.METHODS: Fifty cases of chronic hepatitis B and posthepatic cirrhosis with positive serum HBsAg, HBeAg, anti-Hbc and HBV-DNA were divided randomly and single-blindly into the treatment group (treated with ZYW) and the control group (treated with interferon).After 3 month treatment,the effects of the treatment group and the control group were evaluated.RESULTS: The serum ALT normalization was 83.3%(30/36) in the treatment group and 85.7%(12/14) in the control group,with no significant difference (X^2=0.043, P>0.05).After the course, the negative expression rates of the serum HBV-DNA and HBeAg were 44.4%(16/36) and 50%(18/36) in the treatment group, and 50%(7/14) and 50%(7/14) in the control group, respectively,with no significant difference(X^2=0.125, X^2=0.00, both P>0.05). Negative HBsAg and positive HBsAb appeared in 4 cases of the treatment group and 1 case of the control group.Serum anti-HBc turned negative in 6 cases of the treatment group and 1 case of the control group, respectively. After the ZYW treatment,serum CD3^+, CD4^+, CD8^+, CD4^+/CD8^+ and NK cell activation were significantly increased. Only serum CD3^+ and NK cell activation were significantly increased in the control group with a significant difference between the two groups. The serum C4, C1q, C3, B and C9 were significantly in creased inthe treatment group. In the control group only the serum C4 was increased. The concentration of serum interferon had no change after treatment with ZYW, while it was significantly increased in the control group after treatment with interferon.The ultrastructure of the liver restored,which helped effectively to reduce the degeneration and necrosis of hepatic cells,infiltration of inflammatory cells and hepatic cirrhosis.CONCLUSION:ZYW is a pure Chinese herbal medicine. It can exert potent therapeutic effects on chronic hepatitis B and po展开更多
Diabetic cardiomyopathy(DCM)is a common complication in diabetic patients.The molecular mechanisms of DCM remain to be fully elucidated.The intronic long noncoding RNA of DACH1(lnc DACH1)has been demonstrated to be cl...Diabetic cardiomyopathy(DCM)is a common complication in diabetic patients.The molecular mechanisms of DCM remain to be fully elucidated.The intronic long noncoding RNA of DACH1(lnc DACH1)has been demonstrated to be closely associated with heart failure and cardiac regeneration.In this study,we investigated the role of lnc DACH1 in DCM and the underlying molecular mechanisms.The expression of lnc DACH1 was increased in DCM hearts and in high glucose-treated cardiomyocytes.Knockout of lnc DACH1 reduced mitochondrial oxidative stress,cell apoptosis,cardiac fibrosis and hypertrophy,and improved cardiac function in DCM mice.Overexpression of lnc DACH1 exacerbated mitochondria-derived reactive oxygen species(ROS)level and apoptosis,decreased activity of manganese superoxide dismutase(Mn-SOD);while silencing of lnc DACH1 attenuated ROS production,mitochondrial dysfunction,cell apoptosis,and increased the activity of Mn-SOD in cardiomyocytes treated with high glucose.Lnc DACH1 directly bound to sirtuin3(SIRT3)and facilitated its degradation by ubiquitination,therefore promoting mitochondrial oxidative injury and cell apoptosis in mouse hearts.In addition,SIRT3 silencing abrogated the protective effects of lnc DACH1 deficiency in cardiomyocytes.In summary,lnc DACH1 aggravates DCM by promoting mitochondrial oxidative stress and cell apoptosis via increasing ubiquitination-mediated SIRT3 degradation in mouse hearts.Inhibition of lnc DACH1 represents a novel therapeutic strategy for the intervention of diabetic cardiomyopathy.展开更多
In order to reveal the changes of vegetation in southern China since the Last Glacial Maximum, we have established high-resolution time scales and palynological sequences of borehole profiles by drilling cores in some...In order to reveal the changes of vegetation in southern China since the Last Glacial Maximum, we have established high-resolution time scales and palynological sequences of borehole profiles by drilling cores in some weak areas of the research to restore vegetation changes over the past 20,000 years on the basis of previous work. This paper gives the vegetation zoning maps of 18, 9 and 6 ka BP respectively in southern China, and describes the distribution characteristics of plants in different zones/subzones. The results show that the vegetation zonations around 18 ka BP were significantly different from that at present.It appeared in turn with Cold-temperate coniferous forest and alpine meadow steppe zone, and Temperate mixed coniferous and broad-leaved forest zone/warm temperate deciduous broad-leaved forest zone from northwest to southeast in the west, and Temperate mixed coniferous and broad-leaved forest zone, Warm temperate deciduous broad-leaved forest zone, and Northern subtropical mixed evergreen and deciduous broad-leaved forest zone from north to south in the central and east. The vegetation distribution around 9 ka BP changed distinctively. Except that the northwest part was located in Mountain temperate mixed coniferous and broad-leaved forest zone, the vegetation in other areas occurred in turn with North subtropical mixed evergreen and deciduous broad-leaved forest subzone, Mid-subtropical typical evergreen broad-leaved forest subzone, and South subtropical monsoon evergreen broad-leaved forest subzone/Tropical seasonal rainforest and rainforest zone from north to south.There was little change in the appearance of vegetation zonations between 6 and 9 ka BP, but the northern edge of each vegetation belt moved a little northward, reflecting that the overall climate became warmer around 6 ka BP. The vegetation changes in southern China over the past 20,000 years were largely driven by environmental changes. Climate change was the main factor affecting the vegetation distribution. The impact of human 展开更多
A silver-based metal-organic framework（Ag-MOFs）, [Ag2（H3 ddcba）（dpp）2]（1）（H5 ddcba = 3,5-（di（2’,5’-dicarboxylphenyl）benozoic acid, dpp = 1,3-di（4-pyridyl）propane）, was successfully constructed via hyd...A silver-based metal-organic framework（Ag-MOFs）, [Ag2（H3 ddcba）（dpp）2]（1）（H5 ddcba = 3,5-（di（2’,5’-dicarboxylphenyl）benozoic acid, dpp = 1,3-di（4-pyridyl）propane）, was successfully constructed via hydrothermal assembly of a pentacaboxylate ligand, a N-donor ligand and Ag（I） ions, which possesses a pcu topology and exhibits excellent catalytic properties in aqueous solution for the degradation of onitrophenol（2-NP）, m-nitrophenol（3-NP） and p-nitrophenol（4-NP）. Related kinetics of such catalytic reactions, photoluminescent and thermal stability of compound 1 were also investigated.展开更多
In order to ensure safe mining and reduce surface damage in shallow multi-seam mining,the failure characteristics of interburden strata with different coal pillars offset distances between pillars in the upper and low...In order to ensure safe mining and reduce surface damage in shallow multi-seam mining,the failure characteristics of interburden strata with different coal pillars offset distances between pillars in the upper and lower seams,the distribution characteristics of stress concentration in coal pillars,and the development characteristics of stratum cracks and subsidence were investigated by physical and UDEC2D simulation.Meanwhile,the effect of different coal pillar offset distances on stress concentration of coal pillar and development of stratum cracks were studied.Based on those results,a formula for safe mining and reducing surface damage was established,which provided a theoretical basis for safe and environmentally friendly mining in shallow multi-seam.According to the results,the optimal coal pillar offset distance(the side to side horizontal distance of the upper and lower coal pillars)between the upper and lower coal seams was developed to reduce the stress concentration of coal pillars and surface damage.The results of this study have been applied in Ningtiaota coal mine and have achieved good results in safe and environmentally friendly mining.展开更多
Subcutaneous fat(SCF)and intramuscular fat(IMF)deposition is relevant to health in humans,as well as meat production and quality in pigs.In this study,we generated RNA sequence data for 122 SCF,120 IMF,and 87 longissi...Subcutaneous fat(SCF)and intramuscular fat(IMF)deposition is relevant to health in humans,as well as meat production and quality in pigs.In this study,we generated RNA sequence data for 122 SCF,120 IMF,and 87 longissimus dorsi muscle(LDM)samples using 155 F6 pigs from a specially designed heterogeneous population generated by intercrossing four highly selected European commercial breeds and four indigenous Chinese pig breeds.The phenotypes including waist back fat thickness and intramuscular fat content were also measured in the 155 F6 pigs.We found that the genes in SCF and IMF differed largely in both expression levels and network connectivity,and highlighted network modules that exhibited strongest gain of connectivity in SCF and IMF,containing genes that were associated with the immune process and DNA double-strand repair,respectively.We identified 215 SCF genes related to kinase inhibitor activity,mitochondrial fission,and angiogenesis,and 90 IMF genes related to lipolysis and fat cell differentiation,displayed a tissue-specific association with back fat thickness and IMF content,respectively.We found that cis-expression QTL for trait-associated genes in the two adipose tissues tended to have tissuedependent predictability for the two adipose traits.Alternative splicing of genes was also found to be associated with SCF or IMF deposition,but the association was much less extensive than that based on expression levels.This study provides a better understanding of SCF and IMF gene transcription and network organization and identified critical genes and network modules that displayed tissue-specific associations with subcutaneous and intramuscular fat deposition.These features are helpful for designing breeding programs to genetically improve the two adipose traits in a balanced way.展开更多
Turbulent fluidized bed reactors are widely used in industry. However, CFD simulations of the hydrody- namic characteristics of these reactors are relatively sparse, despite the urgent demand from industry. To address...Turbulent fluidized bed reactors are widely used in industry. However, CFD simulations of the hydrody- namic characteristics of these reactors are relatively sparse, despite the urgent demand from industry. To address this problem, Eulerian simulations with an EMMS-based sub-grid scale model, accounting for the effect of sub-grid scale structures on the inter-phase friction, are performed to study the hydrodynamics inside a large-scale turbulent fluidized bed of FCC particles. It is shown that the simulated axial and radial solid concentration profiles, entrained solid fluxes and standard deviation of the solid concentration fluc- tuation agreed well with experimental data available in the literature. In-depth analysis of time-averaged particle velocity and solid concentration shows that a dense-suspension upflow regime coexists with fast fluidization regime in this bed, which is reminiscent of the hydrodynamic characteristics in high-density circulating fluidized bed （CFB） risers, even though they are operated in different fluidization regimes. The Reynolds stresses in turbulent fluidized beds are anisotropic, but the degree of anisotropy is far less pro- nounced than the reported values in CFB risers. It was also found that the solid concentration fluctuation and axial particle velocity fluctuation are strongly correlated. 2009 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.展开更多
Background Congenital heart disease with severe pulmonary arterial hypertension （SPAH）,previously thought to have irreversible pulmonary vascular disease （PVD）,has been recently successfully corrected using diagno...Background Congenital heart disease with severe pulmonary arterial hypertension （SPAH）,previously thought to have irreversible pulmonary vascular disease （PVD）,has been recently successfully corrected using diagnostic treatment and repair strategy by our surgery team.This study aimed to evaluate the midterm results of a selected cohort of older patients with nonrestrictive ventricular septal defect （VSD） and SPAH using diagnostic treatment and repair strategy.Methods The records of 56 patients older than six years with nonrestrictive VSD and SPAH undergoing diagnostic treatment and repair strategy from 2006 to 2012 were retrospectively reviewed.All patients received advanced pulmonary arterial hypertension （PAH） therapy and radical repairs were performed when transcutaneous oxygen saturation （SPO2） increased up to 93％.Results There were no operative deaths.SPO2 and baseline six-minute walk test （SMWT） distance of all selected patients increased significantly and mean pulmonary artery pressure （MPAP） regressed significantly after diagnostic treatment and at late follow-up （P ＜0.01）.The incidence of late postoperative PAH was seen in six （10.7％） patients and by Logistic regression analysis,early postoperative PAH was an independent risk factor related to late postoperative PAH.Conclusions Diagnostic treatment and repair strategy was effective and safe for treatment of nonrestrictive VSD and SPAH and the midterm results were excellent.Diagnostic treatment strategy was effective in assessing the reversibility of SPAH in older patients associated with nonrestrictive VSD and the PVD in these selective patients is generally reversible.展开更多
All-solid-state lithium metal batteries(ASSLMBs)with solid electrolytes(SEs)have emerged as a promising alternative to liquid electrolyte-based Li-ion batteries due to their higher energy density and safety.However,si...All-solid-state lithium metal batteries(ASSLMBs)with solid electrolytes(SEs)have emerged as a promising alternative to liquid electrolyte-based Li-ion batteries due to their higher energy density and safety.However,since ASSLMBs lack the wetting properties of liquid electrolytes,they require stacking pressure to prevent contact loss between electrodes and SEs.Though previous studies showed that stacking pressure could impact certain performance aspects,a comprehensive investigation into the effects of stacking pressure has not been conducted.To address this gap,we utilized the Li_(6)PS_(5)Cl solid electrolyte as a reference and investigated the effects of stacking pressures on the performance of SEs and ASSLMBs.We also developed models to explain the underlying origin of these effects and predict battery performance,such as ionic conductivity and critical current density.Our results demonstrated that an appropriate stacking pressure is necessary to achieve optimal performance,and each step of applying pressure requires a specific pressure value.These findings can help explain discrepancies in the literature and provide guidance to establish standardized testing conditions and reporting benchmarks for ASSLMBs.Overall,this study contributes to the understanding of the impact of stacking pressure on the performance of ASSLMBs and highlights the importance of careful pressure optimization for optimal battery performance.展开更多
The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the result...The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the results of multi-center clinical nutrition research for congenital heart disease following thefirst Chinese consensus edition of 2016.The consensus was also shaped by the results of three discussion sessions and two questionnaires con-ducted by the 13-member collaboration group.This process was informed by both clinical guidelines and expert consensus.The quality of literature,both in English and Chinese,and the level of recommendations were evaluated using the Grading of Recommendations Assessment,Development,and Evaluations(GRADE)system.展开更多
Graphitic carbon nitride(g-C3N4)-based photocatalysts have shown great potential in the splitting of water.However,the intrinsic drawbacks of g-C3N4,such as low surface area,poor diffusion,and charge separation effici...Graphitic carbon nitride(g-C3N4)-based photocatalysts have shown great potential in the splitting of water.However,the intrinsic drawbacks of g-C3N4,such as low surface area,poor diffusion,and charge separation efficiency,remain as the bottleneck to achieve highly efficient hydrogen evolution.Here,a hollow oxygen-incorporated g-C3N4 nanosheet(OCN)with an improved surface area of 148.5 m2 g^−1 is fabricated by the multiple thermal treatments under the N2/O2 atmosphere,wherein the C–O bonds are formed through two ways of physical adsorption and doping.The physical characterization and theoretical calculation indicate that the O-adsorption can promote the generation of defects,leading to the formation of hollow morphology,while the O-doping results in reduced band gap of g-C3N4.The optimized OCN shows an excellent photocatalytic hydrogen evolution activity of 3519.6μmol g^−1 h^−1 for~20 h,which is over four times higher than that of g-C3N4(850.1μmol g^−1 h^−1)and outperforms most of the reported g-C3N4 catalysts.展开更多
Flexible lithium metal batteries with high capacity and power density have been regarded as the core power resources of wearable electronics.However,the main challenge lies in the limited electrochemical performance o...Flexible lithium metal batteries with high capacity and power density have been regarded as the core power resources of wearable electronics.However,the main challenge lies in the limited electrochemical performance of solid-state polymer electrolytes,which hinders further practical applications.Incorporating functional inorganic additives is an effective approach to improve the performance,including increasing ionic conductivity,achieving dendrite inhibiting capability,and improving safety and stability.Herein,this review summarizes the latest developments of functional inorganic additives in composite solid-state electrolytes for flexible metal batteries with special emphasis on their mechanisms,strategies,and cutting-edge applications,in particular,the relationship between them is discussed in detail.Finally,the perspective on future research directions and the key challenges on this topic are outlooked.展开更多
Three small molecules with the same arms and different cores of perylene diimide(PDI)or indaceno[2,1-b:6,5-b']dithiophene(IDT)were designed and synthesized as the acceptor materials for P3HT-based bulk-heterojunct...Three small molecules with the same arms and different cores of perylene diimide(PDI)or indaceno[2,1-b:6,5-b']dithiophene(IDT)were designed and synthesized as the acceptor materials for P3HT-based bulk-heterojunction(BHJ)solar cells.The impacts of the different cores on the optical absorption,electrochemical properties,electron mobility,film morphology,photoluminescene characteristics,and solar cell performance were thoroughly studied.The three compounds possess a broad absorption covering the wavelength range of 400–700 nm and relatively low lowest unoccupied molecular orbital(LUMO)energy levels of?3.86,?3.81 and?3.99 eV.The highest power conversion efficiency of 0.82%was achieved for the BHJ solar cells based on SM3 as the acceptor material,the compound with a PDI core.展开更多
文摘AIM: To establish a method to detect the expression of the tumor specific growth factor TSGF, CA242 and CA19-9 in serum and evaluate their value in diagnosis of pancreatic cancer. METHODS: ELISA and Biochemical colorimetric assay were used to detect the serum content of TSGF, CA242 and CA19-9 in 200 normal cases, 52 pancreatitis patients and 96 pancreatic cancer patients. RESULTS: The positive likelihood ratios of TSGF, CA242 and CA19-9 were 5.4, 12.6 and 6.3, respectively, and their negative likelihood ratios were 0.10, 0.19 and 0.17, respectively. With single tumor marker diagnosed pancreatic cancer, the highest sensitivity and specificity of TSGF were 91.6% and 93.5%. In combined test with 3 markers, when all of them were positive, the sensitivity changed to 77.0% and the specificity and the positive predictive value were 100%. The levels of TSGF and CA242 were significantly higher in the patients with pancreatic cancer of head than those in the patients with pancreatic cancer of body, tail and whole pancreas, but the expression of CA19-9 had no correlation with the positions of the pancreatic cancer. The sensitivity of TSGF, CA242 and CA19-9 was increased with the progress in stages of pancreatic cancer. In stage I, the sensitivity of TSGF was markedly higher than CA242 and CA19-9. CONCLUSION: The combined use of TSGF, CA242 and CA19-9 expressions can elevate the specificity for pancreatmc cancer diagnosis. And it shows that it plays an important role to differentiate positions and tissue typing. It is a forepart diagnosis for the pancreatic cancer by combination checking. There is very important correlation between the three markers and the pancreatic cancer.
基金supported by the National Natural Science Foundation of China (U1401244, 21374025,21372053,21572041,and 51503050)the National Key Research and Development Program of China (2017YFA0206600)+2 种基金the State Key Laboratory of Luminescent Materials and Devices(2016-skllmd-05)the Youth Association for Promoting Innovation(CAS)the U.S.Office of Naval Research(N00014-15-1-2244)for financial support
文摘Nonfullerene-based organic solar cells(NFOSCs)have received great interest recently due to their higher performance and greater potential compared with fullerene-based solar cells[1].Power conversion efficiencies(PCEs)over 13% have been realized in single-junction NFOSCs[2].Compared with traditional fullerene acceptors,the greatest advantage of nonfullerene acceptors is their stronger light-harvesting capability in the visible and
基金an introductory part of a project supported by National Science Foundation of China(No.39993430).
文摘As a part of a basic research project on Xeno-transplantion. we have been engaged in the derivation of embryonic stein cell lines from Chinese mini swine. Here, we reported for the first time the establishment of two porcine EG cell lines (BPEG1 and BPEG2) from primordial germ cells of genital ridges of a 28 and a 27 d embryos respectively. Their pluripotent nature has been identified by colony morphology, marker characterization as well as by in vitro and in vivo differentiation. These porcine EG cells are potentially useful for further basic studies.
基金Research fund for earthquake engineering of China Earthquake Administration(201508023)a project of the National Science&Technology Support Program during the Twelfth Five-year Plan Period of China(2015BAK17B03)a general program of National Natural Science Foundation of China(51578515)
文摘Severe damage to suspended ceilings of metal grids and lay-in panels was observed in public buildings during the 2013 M7.0 Lushan earthquake in China. Over the past several years, suspended ceilings have been widely used practice in public buildings throughout China, including government offices, schools and hospitals. To investigate the damage mechanism of suspended ceilings, a series of three-dimensional shake table tests was conducted to reproduce the observed damage. A full-scale reinforced concrete frame was constructed as the testing frame for the ceiling, which was single-story and infilled with brick masonry walls to represent the local construction of low-rise buildings. In general, the ceiling in the tests exhibited similar damage phenomena as the field observations, such as higher vulnerability of perimeter elements and extensive damage to the cross runners. However, it exhibited lower fragility in terms of peak ground/roof accelerations at the initiation of damage. Further investigations are needed to clarify the reasons for this behavior.
基金the National Science and Technology Supporting Program(2012BAK15B02)the National Natural Science Foundation Program(50938006)the special program for Science Field Investigation on Lushan M7.0 Earthquake from the China Earthquake Administration
文摘Severe damage to steel space structures is rarely reported when compared to other structural systems damaged during past major earthquakes around the world. Two gymnasiums of steel space structures in downtown Lushan County that were damaged during the 2013 M7.0 Lushan earthquake in China were investigated and the observations are summarized in this paper. Typical damage to these two steel space structures ranges from moderate to severe. Moderate damage includes global buckling and dislocation of bolted connections of truss members, and inelastic elongation of anchor bolts and sliding of pedestal plates of supports. Severe damage includes member fracture caused by local buckling, and fracture failure of anchor bolts and welds. The distribution of structural damage to these two structures is described in detail and future research opportunities are suggested.
基金supported by the China Geological Survey Project(DD20160060,121201140 42901)the National Natural Science Foundation of China(41502119,41371207)
文摘Sedimentary sequences in the Subei Basin are complex and have been affected by interactions between the ocean and rivers since the Late Pliocene, including the Yellow River, Huaihe River, and the Yangtze River. This sedimentary evolution, in particular the timing of Pleistocene transgressions, has long been a matter of controversy owing to the lack of precise chronological evidence. The aim of this study is to explore the evolution of the sedimentary environment throughout the past 3.00 Ma in this region on the basis of a comprehensive analysis of particle size and foraminifera and ostracods collected in the TZK9 core from the Subei Basin combined with geochronological studies of magnetostratigraphy, AMS^(14)C and optically stimulated luminescence(OSL). The results show that fluvial facies in the sedimentary environment from 3.00 to 1.01 Ma. There were fluvial facies and reflects six sea-level high stands from 1.01 to 0.25 Ma. The study area was affected by four large-scale transgressions since 0.25 Ma. The four marine sedimentary layers known as DU7(buried at 48–52 m), DU5(buried at 35–41 m), DU3(buried at 16–23 m), and DU1(buried at 2–4 m) are recorded in the MIS7(210–250 ka), MIS5, MIS3, and Holocene, respectively. The magnitude of the DU5 transgression was identical to that of the DU3 transgression, both were larger than the DU7 transgression, and the DU1 transgression was the weakest. The variation of transgression strength reflects the influence of global changes in sea level, tectonic subsidence, shell ridges, and sand dams. In the TZK9 core, we found evidence of seven sea-level high stands from the Early–Middle Pleistocene, and the first one caused by regional rapid subsidence and could be traced back to 0.83-0.84 Ma. The sea-level high stands and the age of the first one recorded above was different from other cores in eastern China, this was caused by the lack of absolute age control and the differences in paleotopography during this period. This study reconstructs sedimentary evolution, det
基金Scientific Research Fund of IEM,CEA under Grant Nos.2016B09,2014B12China Natural Science Foundation under Grant Nos.51478442,51408565
文摘Porcelain electrical equipment （PEE）, such as current transformers, is critical to power supply systems, but its seismic performance during past earthquakes has not been satisfactory. This paper studies the seismic performance of two typical types of PEE and proposes a damping method for PEE based on multiple tuned mass dampers （MTMD）. An MTMD damping device involving three mass units, named a triple tuned mass damper （TTMD）, is designed and manufactured. Through shake table tests and finite element analysis, the dynamic characteristics of the PEE are studied and the effectiveness of the MTMD damping method is verified. The adverse influence of MTMD redundant mass to damping efficiency is studied and relevant equations are derived. MTMD robustness is verified through adjusting TTMD control frequencies. The damping effectiveness of TTMD, when the peak ground acceleration far exceeds the design value, is studied. Both shake table tests and finite element analysis indicate that MTMD is effective and robust in attenuating PEE seismic responses. TTMD remains effective when the PGA far exceeds the design value and when control deviations are considered.
基金Supported by the Natural Science Foundation of Shandong Province,No.1999CA 1CKB3
文摘AIM:To study the therapeutic effects of zhaoyangwan (ZYW) on chronic hepatitis B and hepatic cirrhosis and the anti-virus, anti-fibrosis and immunoregulatory mechanisms of ZYW.METHODS: Fifty cases of chronic hepatitis B and posthepatic cirrhosis with positive serum HBsAg, HBeAg, anti-Hbc and HBV-DNA were divided randomly and single-blindly into the treatment group (treated with ZYW) and the control group (treated with interferon).After 3 month treatment,the effects of the treatment group and the control group were evaluated.RESULTS: The serum ALT normalization was 83.3%(30/36) in the treatment group and 85.7%(12/14) in the control group,with no significant difference (X^2=0.043, P>0.05).After the course, the negative expression rates of the serum HBV-DNA and HBeAg were 44.4%(16/36) and 50%(18/36) in the treatment group, and 50%(7/14) and 50%(7/14) in the control group, respectively,with no significant difference(X^2=0.125, X^2=0.00, both P>0.05). Negative HBsAg and positive HBsAb appeared in 4 cases of the treatment group and 1 case of the control group.Serum anti-HBc turned negative in 6 cases of the treatment group and 1 case of the control group, respectively. After the ZYW treatment,serum CD3^+, CD4^+, CD8^+, CD4^+/CD8^+ and NK cell activation were significantly increased. Only serum CD3^+ and NK cell activation were significantly increased in the control group with a significant difference between the two groups. The serum C4, C1q, C3, B and C9 were significantly in creased inthe treatment group. In the control group only the serum C4 was increased. The concentration of serum interferon had no change after treatment with ZYW, while it was significantly increased in the control group after treatment with interferon.The ultrastructure of the liver restored,which helped effectively to reduce the degeneration and necrosis of hepatic cells,infiltration of inflammatory cells and hepatic cirrhosis.CONCLUSION:ZYW is a pure Chinese herbal medicine. It can exert potent therapeutic effects on chronic hepatitis B and po
基金supported by the National Natural Science Foundation of China(81730012,81872871,and 82070283)CAMS Innovation Fund for Medical Sciences(2020-I2M-5-003)。
文摘Diabetic cardiomyopathy(DCM)is a common complication in diabetic patients.The molecular mechanisms of DCM remain to be fully elucidated.The intronic long noncoding RNA of DACH1(lnc DACH1)has been demonstrated to be closely associated with heart failure and cardiac regeneration.In this study,we investigated the role of lnc DACH1 in DCM and the underlying molecular mechanisms.The expression of lnc DACH1 was increased in DCM hearts and in high glucose-treated cardiomyocytes.Knockout of lnc DACH1 reduced mitochondrial oxidative stress,cell apoptosis,cardiac fibrosis and hypertrophy,and improved cardiac function in DCM mice.Overexpression of lnc DACH1 exacerbated mitochondria-derived reactive oxygen species(ROS)level and apoptosis,decreased activity of manganese superoxide dismutase(Mn-SOD);while silencing of lnc DACH1 attenuated ROS production,mitochondrial dysfunction,cell apoptosis,and increased the activity of Mn-SOD in cardiomyocytes treated with high glucose.Lnc DACH1 directly bound to sirtuin3(SIRT3)and facilitated its degradation by ubiquitination,therefore promoting mitochondrial oxidative injury and cell apoptosis in mouse hearts.In addition,SIRT3 silencing abrogated the protective effects of lnc DACH1 deficiency in cardiomyocytes.In summary,lnc DACH1 aggravates DCM by promoting mitochondrial oxidative stress and cell apoptosis via increasing ubiquitination-mediated SIRT3 degradation in mouse hearts.Inhibition of lnc DACH1 represents a novel therapeutic strategy for the intervention of diabetic cardiomyopathy.
基金supported by the Strategic Priority Research Program of Chinese Academy of Sciences (Grant Nos. XDA05120100 & XDB26000000)the National Natural Science Foundation of China (Grant Nos. 41771219, 41371207 & 41472010)
文摘In order to reveal the changes of vegetation in southern China since the Last Glacial Maximum, we have established high-resolution time scales and palynological sequences of borehole profiles by drilling cores in some weak areas of the research to restore vegetation changes over the past 20,000 years on the basis of previous work. This paper gives the vegetation zoning maps of 18, 9 and 6 ka BP respectively in southern China, and describes the distribution characteristics of plants in different zones/subzones. The results show that the vegetation zonations around 18 ka BP were significantly different from that at present.It appeared in turn with Cold-temperate coniferous forest and alpine meadow steppe zone, and Temperate mixed coniferous and broad-leaved forest zone/warm temperate deciduous broad-leaved forest zone from northwest to southeast in the west, and Temperate mixed coniferous and broad-leaved forest zone, Warm temperate deciduous broad-leaved forest zone, and Northern subtropical mixed evergreen and deciduous broad-leaved forest zone from north to south in the central and east. The vegetation distribution around 9 ka BP changed distinctively. Except that the northwest part was located in Mountain temperate mixed coniferous and broad-leaved forest zone, the vegetation in other areas occurred in turn with North subtropical mixed evergreen and deciduous broad-leaved forest subzone, Mid-subtropical typical evergreen broad-leaved forest subzone, and South subtropical monsoon evergreen broad-leaved forest subzone/Tropical seasonal rainforest and rainforest zone from north to south.There was little change in the appearance of vegetation zonations between 6 and 9 ka BP, but the northern edge of each vegetation belt moved a little northward, reflecting that the overall climate became warmer around 6 ka BP. The vegetation changes in southern China over the past 20,000 years were largely driven by environmental changes. Climate change was the main factor affecting the vegetation distribution. The impact of human
基金financial support from the National Science Foundation of China (Nos. 216731272, 2137312, 21671119, 51572152 and 51502155)
文摘A silver-based metal-organic framework（Ag-MOFs）, [Ag2（H3 ddcba）（dpp）2]（1）（H5 ddcba = 3,5-（di（2’,5’-dicarboxylphenyl）benozoic acid, dpp = 1,3-di（4-pyridyl）propane）, was successfully constructed via hydrothermal assembly of a pentacaboxylate ligand, a N-donor ligand and Ag（I） ions, which possesses a pcu topology and exhibits excellent catalytic properties in aqueous solution for the degradation of onitrophenol（2-NP）, m-nitrophenol（3-NP） and p-nitrophenol（4-NP）. Related kinetics of such catalytic reactions, photoluminescent and thermal stability of compound 1 were also investigated.
基金The article was funded by the National Natural Science Foundation of China(Nos.51674190 and 52074211)the Natural Science Basic Research Program of Shaanxi(Nos.2019JQ-798 and 2019JLP-08).The authors also thank the reviewers for their patient work.
文摘In order to ensure safe mining and reduce surface damage in shallow multi-seam mining,the failure characteristics of interburden strata with different coal pillars offset distances between pillars in the upper and lower seams,the distribution characteristics of stress concentration in coal pillars,and the development characteristics of stratum cracks and subsidence were investigated by physical and UDEC2D simulation.Meanwhile,the effect of different coal pillar offset distances on stress concentration of coal pillar and development of stratum cracks were studied.Based on those results,a formula for safe mining and reducing surface damage was established,which provided a theoretical basis for safe and environmentally friendly mining in shallow multi-seam.According to the results,the optimal coal pillar offset distance(the side to side horizontal distance of the upper and lower coal pillars)between the upper and lower coal seams was developed to reduce the stress concentration of coal pillars and surface damage.The results of this study have been applied in Ningtiaota coal mine and have achieved good results in safe and environmentally friendly mining.
基金supported by funds from the National Natural Science Foundation of China.
文摘Subcutaneous fat(SCF)and intramuscular fat(IMF)deposition is relevant to health in humans,as well as meat production and quality in pigs.In this study,we generated RNA sequence data for 122 SCF,120 IMF,and 87 longissimus dorsi muscle(LDM)samples using 155 F6 pigs from a specially designed heterogeneous population generated by intercrossing four highly selected European commercial breeds and four indigenous Chinese pig breeds.The phenotypes including waist back fat thickness and intramuscular fat content were also measured in the 155 F6 pigs.We found that the genes in SCF and IMF differed largely in both expression levels and network connectivity,and highlighted network modules that exhibited strongest gain of connectivity in SCF and IMF,containing genes that were associated with the immune process and DNA double-strand repair,respectively.We identified 215 SCF genes related to kinase inhibitor activity,mitochondrial fission,and angiogenesis,and 90 IMF genes related to lipolysis and fat cell differentiation,displayed a tissue-specific association with back fat thickness and IMF content,respectively.We found that cis-expression QTL for trait-associated genes in the two adipose tissues tended to have tissuedependent predictability for the two adipose traits.Alternative splicing of genes was also found to be associated with SCF or IMF deposition,but the association was much less extensive than that based on expression levels.This study provides a better understanding of SCF and IMF gene transcription and network organization and identified critical genes and network modules that displayed tissue-specific associations with subcutaneous and intramuscular fat deposition.These features are helpful for designing breeding programs to genetically improve the two adipose traits in a balanced way.
基金supported by National Natural Science Foundation of China under the grants Nos. 20336040,20490201 and 20221603the Chinese Academy of Science sunder the grant KJCX-SW-L08
文摘Turbulent fluidized bed reactors are widely used in industry. However, CFD simulations of the hydrody- namic characteristics of these reactors are relatively sparse, despite the urgent demand from industry. To address this problem, Eulerian simulations with an EMMS-based sub-grid scale model, accounting for the effect of sub-grid scale structures on the inter-phase friction, are performed to study the hydrodynamics inside a large-scale turbulent fluidized bed of FCC particles. It is shown that the simulated axial and radial solid concentration profiles, entrained solid fluxes and standard deviation of the solid concentration fluc- tuation agreed well with experimental data available in the literature. In-depth analysis of time-averaged particle velocity and solid concentration shows that a dense-suspension upflow regime coexists with fast fluidization regime in this bed, which is reminiscent of the hydrodynamic characteristics in high-density circulating fluidized bed （CFB） risers, even though they are operated in different fluidization regimes. The Reynolds stresses in turbulent fluidized beds are anisotropic, but the degree of anisotropy is far less pro- nounced than the reported values in CFB risers. It was also found that the solid concentration fluctuation and axial particle velocity fluctuation are strongly correlated. 2009 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.
文摘Background Congenital heart disease with severe pulmonary arterial hypertension （SPAH）,previously thought to have irreversible pulmonary vascular disease （PVD）,has been recently successfully corrected using diagnostic treatment and repair strategy by our surgery team.This study aimed to evaluate the midterm results of a selected cohort of older patients with nonrestrictive ventricular septal defect （VSD） and SPAH using diagnostic treatment and repair strategy.Methods The records of 56 patients older than six years with nonrestrictive VSD and SPAH undergoing diagnostic treatment and repair strategy from 2006 to 2012 were retrospectively reviewed.All patients received advanced pulmonary arterial hypertension （PAH） therapy and radical repairs were performed when transcutaneous oxygen saturation （SPO2） increased up to 93％.Results There were no operative deaths.SPO2 and baseline six-minute walk test （SMWT） distance of all selected patients increased significantly and mean pulmonary artery pressure （MPAP） regressed significantly after diagnostic treatment and at late follow-up （P ＜0.01）.The incidence of late postoperative PAH was seen in six （10.7％） patients and by Logistic regression analysis,early postoperative PAH was an independent risk factor related to late postoperative PAH.Conclusions Diagnostic treatment and repair strategy was effective and safe for treatment of nonrestrictive VSD and SPAH and the midterm results were excellent.Diagnostic treatment strategy was effective in assessing the reversibility of SPAH in older patients associated with nonrestrictive VSD and the PVD in these selective patients is generally reversible.
基金supported by National Key Research and Development Program of China(No.2021YFF0500600)Key R&D Projects in Henan Province(221111240100)China Postdoctoral Science Foundation(2022TQ0291 and 2022M712869)
文摘All-solid-state lithium metal batteries(ASSLMBs)with solid electrolytes(SEs)have emerged as a promising alternative to liquid electrolyte-based Li-ion batteries due to their higher energy density and safety.However,since ASSLMBs lack the wetting properties of liquid electrolytes,they require stacking pressure to prevent contact loss between electrodes and SEs.Though previous studies showed that stacking pressure could impact certain performance aspects,a comprehensive investigation into the effects of stacking pressure has not been conducted.To address this gap,we utilized the Li_(6)PS_(5)Cl solid electrolyte as a reference and investigated the effects of stacking pressures on the performance of SEs and ASSLMBs.We also developed models to explain the underlying origin of these effects and predict battery performance,such as ionic conductivity and critical current density.Our results demonstrated that an appropriate stacking pressure is necessary to achieve optimal performance,and each step of applying pressure requires a specific pressure value.These findings can help explain discrepancies in the literature and provide guidance to establish standardized testing conditions and reporting benchmarks for ASSLMBs.Overall,this study contributes to the understanding of the impact of stacking pressure on the performance of ASSLMBs and highlights the importance of careful pressure optimization for optimal battery performance.
基金supported by the National Natural Science Foundation of China(81970265,82270310)a Sub-Project of the National Key R&D Program“The recognition and Identification of Genetic Pathogenic Genes for Structural Birth Defects”(2021YFC2701002)+1 种基金Nanjing Science and Technology Development Project(2019060007)Jiangsu Provincial Key Research and Development Program(BE2023662).
文摘The second edition of the expert consensus on pediatric nutrition was formed based on a global update of pedia-tric nutrition guidelines or consensus worldwide,the management of congenital heart disease,and the results of multi-center clinical nutrition research for congenital heart disease following thefirst Chinese consensus edition of 2016.The consensus was also shaped by the results of three discussion sessions and two questionnaires con-ducted by the 13-member collaboration group.This process was informed by both clinical guidelines and expert consensus.The quality of literature,both in English and Chinese,and the level of recommendations were evaluated using the Grading of Recommendations Assessment,Development,and Evaluations(GRADE)system.
基金This work was supported by the National Science Foundation of China(51772152,51702129,51572114,51972150,21908110,and 51902161)Fundamental Research Funds for the Central Universities(30919011269,30919011110,and 1191030558)+3 种基金Y.W.thanks the Key University Science Research Project of Jiangsu province(16KJB430009)Y.Z.thanks for the support from the Postdoctoral Science Foundation(2018M630527)China Scholarship Council(201708320150)J.S.thanks the Natural Science Foundation of Jiangsu Province(BK20190479,1192261031693).
文摘Graphitic carbon nitride(g-C3N4)-based photocatalysts have shown great potential in the splitting of water.However,the intrinsic drawbacks of g-C3N4,such as low surface area,poor diffusion,and charge separation efficiency,remain as the bottleneck to achieve highly efficient hydrogen evolution.Here,a hollow oxygen-incorporated g-C3N4 nanosheet(OCN)with an improved surface area of 148.5 m2 g^−1 is fabricated by the multiple thermal treatments under the N2/O2 atmosphere,wherein the C–O bonds are formed through two ways of physical adsorption and doping.The physical characterization and theoretical calculation indicate that the O-adsorption can promote the generation of defects,leading to the formation of hollow morphology,while the O-doping results in reduced band gap of g-C3N4.The optimized OCN shows an excellent photocatalytic hydrogen evolution activity of 3519.6μmol g^−1 h^−1 for~20 h,which is over four times higher than that of g-C3N4(850.1μmol g^−1 h^−1)and outperforms most of the reported g-C3N4 catalysts.
基金supported by the Natural Science Foundation of China(No.22179062,52125202,22171136,and U2004209)financial support by the Fundamental Research Funds for the Central Universities(No.30922010303)the financial support by the Natural Science Foundation of Jiangsu Province(BK20220079).
文摘Flexible lithium metal batteries with high capacity and power density have been regarded as the core power resources of wearable electronics.However,the main challenge lies in the limited electrochemical performance of solid-state polymer electrolytes,which hinders further practical applications.Incorporating functional inorganic additives is an effective approach to improve the performance,including increasing ionic conductivity,achieving dendrite inhibiting capability,and improving safety and stability.Herein,this review summarizes the latest developments of functional inorganic additives in composite solid-state electrolytes for flexible metal batteries with special emphasis on their mechanisms,strategies,and cutting-edge applications,in particular,the relationship between them is discussed in detail.Finally,the perspective on future research directions and the key challenges on this topic are outlooked.
基金supported by the National Basic Research Program of China(2014CB643501)the National Natural Science Foundation of China(51073057 and 91233116)+2 种基金the Ministry of Education(NCET-11-0159)the Guangdong Natural Science Foundation(S2012030006232)the Fundamental Research Funds for the Central Universities(2013ZG0007)
文摘Three small molecules with the same arms and different cores of perylene diimide(PDI)or indaceno[2,1-b:6,5-b']dithiophene(IDT)were designed and synthesized as the acceptor materials for P3HT-based bulk-heterojunction(BHJ)solar cells.The impacts of the different cores on the optical absorption,electrochemical properties,electron mobility,film morphology,photoluminescene characteristics,and solar cell performance were thoroughly studied.The three compounds possess a broad absorption covering the wavelength range of 400–700 nm and relatively low lowest unoccupied molecular orbital(LUMO)energy levels of?3.86,?3.81 and?3.99 eV.The highest power conversion efficiency of 0.82%was achieved for the BHJ solar cells based on SM3 as the acceptor material,the compound with a PDI core.
