Objective To analyze the rules of acupoint selection in adjuvant interventions for in vitro fertilization-embryo transfer(IVF-ET)with acupuncture and moxibustion,with the use of complex network technology.Methods Arti...Objective To analyze the rules of acupoint selection in adjuvant interventions for in vitro fertilization-embryo transfer(IVF-ET)with acupuncture and moxibustion,with the use of complex network technology.Methods Articles on clinical trials of acupuncture and moxibustion for IVF-ET were searched in the China National Knowledge Infrastructure(CNKI),Wanfang,VIP,PubMed,and Web of Science databases from inception to January 31,2020.A database of acupoint prescriptions has been established.Descriptive analysis was conducted using Microsoft Excel 2019,association rule analysis was conducted using SPSS Modeler 18.0 Apriori algorithm,clustering analysis of high-frequency acupoints was performed using SPSS 25.0 Ward,and complex network analysis of acupoints was performed by using Gephi 0.9.2.Results A total of 124 clinical trials were included,and 187 acupoint prescriptions were extracted,for a total of 91 acupoints.The total frequency of using these acupoints was 1,296 times,with Sānyīnjiāo(三阴交SP6)used the most frequently.The acupoints were generally located around the conception vessel,spleen meridian,and stomach meridian,and they were mainly distributed in the lower extremities,chest,and abdomen.Considerable consideration was paid to the specific points.The association rule analysis showed that the highest correlation presented between Guānyuán(关元CV4)and Zĭgōng(子宫EX-CA1).Complex network k-core hierarchical analysis discovered that CV4,SP6,Xuèhăi(血海SP10),Hégŭ(合谷LI4),Tàichōng(太冲LR3),Qìhăi(气海CV6),and EX-CA1 were the core acupoints in adjuvant interventions with acupuncture-moxibustion for IVF-ET.Conclusion In adjuvant interventions with acupuncture-moxibustion,acupoints were commonly located around the conception vessel,spleen meridian,and stomach meridian,and the convergent point was particularly used as a specific point.The acupoints were selected to smooth the liver qi,remove stagnation,activate blood circulation,resolve stasis,and benefit the liver and kidney.“CV4→SP6�展开更多
Negative differential conductance(NDC)serves as a crucial characteristic that reveals various underlying physics and transport process in hybrid superconducting devices.We report the observation of gate-tunable NDC ou...Negative differential conductance(NDC)serves as a crucial characteristic that reveals various underlying physics and transport process in hybrid superconducting devices.We report the observation of gate-tunable NDC outside the superconducting energy gap on two types of hybrid semiconductor–superconductor devices,i.e.,normal metal–superconducting nanowire–normal metal and normal metal–superconducting nanowire–superconductor devices.Specifically,we study the dependence of the NDCs on back-gate voltage and magnetic field.When the back-gate voltage decreases,these NDCs weaken and evolve into positive differential conductance dips;and meanwhile they move away from the superconducting gap towards high bias voltage,and disappear eventually.In addition,with the increase of magnetic field,the NDCs/dips follow the evolution of the superconducting gap,and disappear when the gap closes.We interpret these observations and reach a good agreement by combining the Blonder–Tinkham–Klapwijk(BTK)model and the critical supercurrent effect in the nanowire,which we call the BTK-supercurrent model.Our results provide an in-depth understanding of the tunneling transport in hybrid semiconductor–superconductor devices.展开更多
Transcendental functions are important functions in various high performance computing applications.Because these functions are time-consuming and the vector units on modern processors become wider and more scalable,t...Transcendental functions are important functions in various high performance computing applications.Because these functions are time-consuming and the vector units on modern processors become wider and more scalable,there is an increasing demand for developing and using vector transcendental functions in such performance-hungry applications.However,the performance of vector transcendental functions as well as their accuracy remain largely unexplored.To address this issue,we perform a comprehensive evaluation of two Single Instruction Multiple Data(SIMD)intrinsics based vector math libraries on two ARMv8 compatible processors.We first design dedicated microbenchmarks that help us understand the performance behavior of vector transcendental functions.Then,we propose a piecewise,quantitative evaluation method with a set of meaningful metrics to quantify their performance and accuracy.By analyzing the experimental results,we find that vector transcendental functions achieve good performance speedups thanks to the vectorization and algorithm optimization.Moreover,vector math libraries can replace scalar math libraries in many cases because of improved performance and satisfactory accuracy.Despite this,the implementations of vector math libraries are still immature,which means further optimization is needed,and our evaluation reveals feasible optimization solutions for future vector math libraries.展开更多
基金Supported by National Natural Science Foundation of China:81774408,81973957,81873371,81804179。
文摘Objective To analyze the rules of acupoint selection in adjuvant interventions for in vitro fertilization-embryo transfer(IVF-ET)with acupuncture and moxibustion,with the use of complex network technology.Methods Articles on clinical trials of acupuncture and moxibustion for IVF-ET were searched in the China National Knowledge Infrastructure(CNKI),Wanfang,VIP,PubMed,and Web of Science databases from inception to January 31,2020.A database of acupoint prescriptions has been established.Descriptive analysis was conducted using Microsoft Excel 2019,association rule analysis was conducted using SPSS Modeler 18.0 Apriori algorithm,clustering analysis of high-frequency acupoints was performed using SPSS 25.0 Ward,and complex network analysis of acupoints was performed by using Gephi 0.9.2.Results A total of 124 clinical trials were included,and 187 acupoint prescriptions were extracted,for a total of 91 acupoints.The total frequency of using these acupoints was 1,296 times,with Sānyīnjiāo(三阴交SP6)used the most frequently.The acupoints were generally located around the conception vessel,spleen meridian,and stomach meridian,and they were mainly distributed in the lower extremities,chest,and abdomen.Considerable consideration was paid to the specific points.The association rule analysis showed that the highest correlation presented between Guānyuán(关元CV4)and Zĭgōng(子宫EX-CA1).Complex network k-core hierarchical analysis discovered that CV4,SP6,Xuèhăi(血海SP10),Hégŭ(合谷LI4),Tàichōng(太冲LR3),Qìhăi(气海CV6),and EX-CA1 were the core acupoints in adjuvant interventions with acupuncture-moxibustion for IVF-ET.Conclusion In adjuvant interventions with acupuncture-moxibustion,acupoints were commonly located around the conception vessel,spleen meridian,and stomach meridian,and the convergent point was particularly used as a specific point.The acupoints were selected to smooth the liver qi,remove stagnation,activate blood circulation,resolve stasis,and benefit the liver and kidney.“CV4→SP6�
基金the National Key Research and Development Program of China(Grant Nos.2022YFA1403400 and 2017YFA0304700)the National Natural Science Foundation of China(Grant Nos.12074417,92065203,92065106,61974138,11774405,11527806,and 12104489)+3 种基金the Strategic Priority Research Program B of Chinese Academy of Sciences(Grant Nos.XDB28000000 and XDB33000000)the Synergetic Extreme Condition User Facility sponsored by the National Development and Reform Commissionthe Innovation Program for Quantum Science and Technology(2021ZD0302600)the support from Youth Innovation Promotion Association,Chinese Academy of Sciences(Grant Nos.2017156 and Y2021043).
文摘Negative differential conductance(NDC)serves as a crucial characteristic that reveals various underlying physics and transport process in hybrid superconducting devices.We report the observation of gate-tunable NDC outside the superconducting energy gap on two types of hybrid semiconductor–superconductor devices,i.e.,normal metal–superconducting nanowire–normal metal and normal metal–superconducting nanowire–superconductor devices.Specifically,we study the dependence of the NDCs on back-gate voltage and magnetic field.When the back-gate voltage decreases,these NDCs weaken and evolve into positive differential conductance dips;and meanwhile they move away from the superconducting gap towards high bias voltage,and disappear eventually.In addition,with the increase of magnetic field,the NDCs/dips follow the evolution of the superconducting gap,and disappear when the gap closes.We interpret these observations and reach a good agreement by combining the Blonder–Tinkham–Klapwijk(BTK)model and the critical supercurrent effect in the nanowire,which we call the BTK-supercurrent model.Our results provide an in-depth understanding of the tunneling transport in hybrid semiconductor–superconductor devices.
基金supported by the National Key Research and Development Program of China under Grant No.2020YFA0709803the National Natural Science Foundation of China under Grant Nos.61902407 and 61802416.
文摘Transcendental functions are important functions in various high performance computing applications.Because these functions are time-consuming and the vector units on modern processors become wider and more scalable,there is an increasing demand for developing and using vector transcendental functions in such performance-hungry applications.However,the performance of vector transcendental functions as well as their accuracy remain largely unexplored.To address this issue,we perform a comprehensive evaluation of two Single Instruction Multiple Data(SIMD)intrinsics based vector math libraries on two ARMv8 compatible processors.We first design dedicated microbenchmarks that help us understand the performance behavior of vector transcendental functions.Then,we propose a piecewise,quantitative evaluation method with a set of meaningful metrics to quantify their performance and accuracy.By analyzing the experimental results,we find that vector transcendental functions achieve good performance speedups thanks to the vectorization and algorithm optimization.Moreover,vector math libraries can replace scalar math libraries in many cases because of improved performance and satisfactory accuracy.Despite this,the implementations of vector math libraries are still immature,which means further optimization is needed,and our evaluation reveals feasible optimization solutions for future vector math libraries.
基金the National Key Research and Development Program of China(2020YFA0309600)the National Natural Science Foundation of China(NSFC+6 种基金61888102,11834017,and 12074413)the Strategic Priority Research Program of Chinese Academy of Sciences(CASXDB30000000 and XDB33000000)Gen Long acknowledges the support from NSFC(12104330)the support from the Elemental Strategy Initiative conducted by the MEXT,Japan(JPMXP0112101001)JSPS KAKENHI(19H05790,20H00354,and 21H05233)A3 Foresight by JSPS。
