Lumpectomy,also called breast-conserving surgery,has become the standard surgical treatment for early-stage breast cancer.However,accurately locating the tumor during a lumpectomy,especially when the lesion is small a...Lumpectomy,also called breast-conserving surgery,has become the standard surgical treatment for early-stage breast cancer.However,accurately locating the tumor during a lumpectomy,especially when the lesion is small and nonpalpable,is a challenge.Such difficulty can lead to either incomplete tumor removal or prolonged surgical time,which result in high re-operation rates(~25%)and increased surgical costs.Here,we report a fiber optoacoustic guide(FOG)with augmented reality(AR)for sub-millimeter tumor localization and intuitive surgical guidance with minimal interference.The FOG is preoperatively implanted in the tumor.Under external pulsed light excitation,the FOG omnidirectionally broadcasts acoustic waves through the optoacoustic effect by a specially designed nano-composite layer at its tip.By capturing the acoustic wave,three ultrasound sensors on the breast skin triangulate the FOG tip’s position with 0.25-mm accuracy.An AR system with a tablet measures the coordinates of the ultrasound sensors and transforms the FOG tip’s position into visual feedback with<1-mm accuracy,thus aiding surgeons in directly visualizing the tumor location and performing fast and accurate tumor removal.We further show the use of a head-mounted display to visualize the same information in the surgeons’first-person view and achieve hands-free guidance.Towards clinical application,a surgeon successfully deployed the FOG to excise a“pseudo tumor”in a female human cadaver.With the high-accuracy tumor localization by FOG and the intuitive surgical guidance by AR,the surgeon performed accurate and fast tumor removal,which will significantly reduce re-operation rates and shorten the surgery time.展开更多
Purpose:Endoscopic transsphenoidal surgery(ETSS)is an increasingly utilized approach for resection of pituitary tumors.Prior studies have evaluated preoperative tumor size,location,and extent as prognostic factors for...Purpose:Endoscopic transsphenoidal surgery(ETSS)is an increasingly utilized approach for resection of pituitary tumors.Prior studies have evaluated preoperative tumor size,location,and extent as prognostic factors for surgical resection.There is little data on the relationship between preoperative pituitary tumor radiographic morphology and surgical outcomes.Study Design:Retrospective longitudinal study.Setting:Single tertiary care institution.Subjects and Methods:Preoperative magnetic resonance imaging and computed tomography scans from patients undergoing ETSS for pituitary tumor resections from 2007 to 2017 were retrospectively evaluated.A neuroradiologist classified these pituitary tumors into six morphologic groups,each defined by volume,dimensions,extension,and shape.Surgical difficulty,rates of incomplete resection,and postoperative complications were then stratified in relation to the morphologic groups.Results:Pituitary tumors from 131 patients were classified from preoperative imaging into six characteristic morphologies:(1)microtumor,(2)round,(3)transverse oblong,(4)superior-inferior oblong,(5)bilobed,and(6)large lobulated.Tumors that were characterized with the large lobulated,bilobed,and transverse oblong morphologies correlated with higher rates of postoperative evidence of residual tumor(70%,36%,and 47%,respectively,all P<0.002).Likewise,large lobulated,bilobed,and transverse oblong morphologies were also associated with intraoperative cerebrospinal fluid leaks(70%,31%,and 35%,respectively,all P<0.05).Conclusions:We describe a novel descriptive system for the morphology of pituitary tumors that can be determined from preoperative imaging.Different tumor morphologic groups are associated with varying degrees of gross tumor resection,complications,and surgical difficulty.Utilizing pituitary tumor morphology may aid surgeons in planning the extent of resection,need for complex closure,and patient counseling.展开更多
A combined lattice Boltzmann and discrete element approach is proposedfor numerical modelling of magnetorheological fluids. In its formulation, the particledynamics is simulated by the discrete element method, while t...A combined lattice Boltzmann and discrete element approach is proposedfor numerical modelling of magnetorheological fluids. In its formulation, the particledynamics is simulated by the discrete element method, while the fluid field is resolvedwith the lattice Boltzmann method. The coupling between the fluid and the particlesare realized through the hydrodynamic interactions. Procedures for computing magnetic, contact and hydrodynamic forces are discussed in detail. The applicability ofthe proposed solution procedure is illustrated via a two-stage simulation of a MR fluidproblem with four different particle volume fractions. At the first stage, simulationsare performed for the particle chain formation upon application of an external magnetic field;and at the second stage, the rheological properties of the MR fluid underdifferent shear loading conditions are investigated with the particle chains establishedat the first stage as the initial configuration.展开更多
The objective of this study was to eval- uate the effects of inorganic phosphorus source and phytase addition on performance, nutrient digestibility and bone mineralization in broiler chickens. In Exp. 1,150 two-day o...The objective of this study was to eval- uate the effects of inorganic phosphorus source and phytase addition on performance, nutrient digestibility and bone mineralization in broiler chickens. In Exp. 1,150 two-day old, male broiler chicks were fed a corn-soybean meal basal diet supplemented with phos- phorus provided by dicalcium phosphate, tricalcium phosphate or defluorinated rock phosphate. Five cages containing 10 birds were allotted to each of the three treatments. In Exp. 2,120 three-day old, male broiler chicks were fed the basal diet from Exp. 1 supplemen- ted with 0,250,500 ,or 1,000 P-＇rU phytase per kg of diet. Six cages containing five chicks were allotted to each of the four treatments. In Exp. 1, there was no difference in weight gain, feed intake or feed conver- sion as a result of feeding the different sources of in- organic phosphorus. The digestibility of phosphorus was significantly lower （P =0.01 ） for chicks fed di- ets supplemented with tricalcium phosphate than for chicks fed the other two diets. However, despite the lower digestibility, serum phosphorus levels did not differ among the three treatments. For Exp. 2, feedconversion showed a linear improvement （P = 0.03 ） with increasing levels of phytase inclusion （ days 0 to 33 ）. Phytase supplementation resulted in linear increa- ses in the digestibility of dry matter （P = 0.02 ）, crude protein （ P --- 0.04 ） and energy （ P 〈 0.01 ）. Chicks fed 1,000 FTU/kg phytase had significantly higher bone calcium （ P = 0.05 ） and bone breaking strength （P = 0.04 ） than chicks fed the basal diet on day 33. In conclusion, the results of the current study indicated that the performance of birds fed diets sup- plemented with dicalcium phosphate, tricalcium phos- phate or defluorinated phosphate was similar and therefore production costs could be lowered by choo- sing the cheapest inorganic phosphorus source when formulating diets for poultry. When diets were formu- lated to meet dietary phosphorus requirements, the gr展开更多
The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of...The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or higher.The STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard Model.The STCF project in China is under development with an extensive R&D program.This document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.展开更多
Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays...Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both channels.With the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,respectively.The branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,respectively.The amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.展开更多
We present a measurement of the integrated luminosity of e^(+)e^(-)collision data collected by the BESIII detector at the BEPCII collider at a center-of-mass energy of Ecm=3.773 GeV.The integrated luminosities of the ...We present a measurement of the integrated luminosity of e^(+)e^(-)collision data collected by the BESIII detector at the BEPCII collider at a center-of-mass energy of Ecm=3.773 GeV.The integrated luminosities of the datasets taken from December 2021 to June 2022,from November 2022 to June 2023,and from October 2023 to February 2024 were determined to be 4.995±0.019 fb^(-1),8.157±0.031 fb^(-1),and 4.191±0.016 fb^(-1),respectively,by analyzing large angle Bhabha scattering events.The uncertainties are dominated by systematic effects,and the statistical uncertainties are negligible.Our results provide essential input for future analyses and precision measurements.展开更多
The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic events.The uncertainty is systematic and the ...The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic events.The uncertainty is systematic and the statistical uncertainty is negligible.Meanwhile,the numbers ofψ(3686)events collected during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,respectively.Both numbers are consistent with the previous measurements within one standard deviation.The total number ofψ(3686)events in the three data samples is(2712.4±14.3)×10~6.展开更多
基金supported by Walther Cancer FoundationNIH grant CA192645 to J.-X.C.NSF SBIR phase I grant 108852 to Vibronix,Inc.
文摘Lumpectomy,also called breast-conserving surgery,has become the standard surgical treatment for early-stage breast cancer.However,accurately locating the tumor during a lumpectomy,especially when the lesion is small and nonpalpable,is a challenge.Such difficulty can lead to either incomplete tumor removal or prolonged surgical time,which result in high re-operation rates(~25%)and increased surgical costs.Here,we report a fiber optoacoustic guide(FOG)with augmented reality(AR)for sub-millimeter tumor localization and intuitive surgical guidance with minimal interference.The FOG is preoperatively implanted in the tumor.Under external pulsed light excitation,the FOG omnidirectionally broadcasts acoustic waves through the optoacoustic effect by a specially designed nano-composite layer at its tip.By capturing the acoustic wave,three ultrasound sensors on the breast skin triangulate the FOG tip’s position with 0.25-mm accuracy.An AR system with a tablet measures the coordinates of the ultrasound sensors and transforms the FOG tip’s position into visual feedback with<1-mm accuracy,thus aiding surgeons in directly visualizing the tumor location and performing fast and accurate tumor removal.We further show the use of a head-mounted display to visualize the same information in the surgeons’first-person view and achieve hands-free guidance.Towards clinical application,a surgeon successfully deployed the FOG to excise a“pseudo tumor”in a female human cadaver.With the high-accuracy tumor localization by FOG and the intuitive surgical guidance by AR,the surgeon performed accurate and fast tumor removal,which will significantly reduce re-operation rates and shorten the surgery time.
文摘Purpose:Endoscopic transsphenoidal surgery(ETSS)is an increasingly utilized approach for resection of pituitary tumors.Prior studies have evaluated preoperative tumor size,location,and extent as prognostic factors for surgical resection.There is little data on the relationship between preoperative pituitary tumor radiographic morphology and surgical outcomes.Study Design:Retrospective longitudinal study.Setting:Single tertiary care institution.Subjects and Methods:Preoperative magnetic resonance imaging and computed tomography scans from patients undergoing ETSS for pituitary tumor resections from 2007 to 2017 were retrospectively evaluated.A neuroradiologist classified these pituitary tumors into six morphologic groups,each defined by volume,dimensions,extension,and shape.Surgical difficulty,rates of incomplete resection,and postoperative complications were then stratified in relation to the morphologic groups.Results:Pituitary tumors from 131 patients were classified from preoperative imaging into six characteristic morphologies:(1)microtumor,(2)round,(3)transverse oblong,(4)superior-inferior oblong,(5)bilobed,and(6)large lobulated.Tumors that were characterized with the large lobulated,bilobed,and transverse oblong morphologies correlated with higher rates of postoperative evidence of residual tumor(70%,36%,and 47%,respectively,all P<0.002).Likewise,large lobulated,bilobed,and transverse oblong morphologies were also associated with intraoperative cerebrospinal fluid leaks(70%,31%,and 35%,respectively,all P<0.05).Conclusions:We describe a novel descriptive system for the morphology of pituitary tumors that can be determined from preoperative imaging.Different tumor morphologic groups are associated with varying degrees of gross tumor resection,complications,and surgical difficulty.Utilizing pituitary tumor morphology may aid surgeons in planning the extent of resection,need for complex closure,and patient counseling.
文摘A combined lattice Boltzmann and discrete element approach is proposedfor numerical modelling of magnetorheological fluids. In its formulation, the particledynamics is simulated by the discrete element method, while the fluid field is resolvedwith the lattice Boltzmann method. The coupling between the fluid and the particlesare realized through the hydrodynamic interactions. Procedures for computing magnetic, contact and hydrodynamic forces are discussed in detail. The applicability ofthe proposed solution procedure is illustrated via a two-stage simulation of a MR fluidproblem with four different particle volume fractions. At the first stage, simulationsare performed for the particle chain formation upon application of an external magnetic field;and at the second stage, the rheological properties of the MR fluid underdifferent shear loading conditions are investigated with the particle chains establishedat the first stage as the initial configuration.
文摘The objective of this study was to eval- uate the effects of inorganic phosphorus source and phytase addition on performance, nutrient digestibility and bone mineralization in broiler chickens. In Exp. 1,150 two-day old, male broiler chicks were fed a corn-soybean meal basal diet supplemented with phos- phorus provided by dicalcium phosphate, tricalcium phosphate or defluorinated rock phosphate. Five cages containing 10 birds were allotted to each of the three treatments. In Exp. 2,120 three-day old, male broiler chicks were fed the basal diet from Exp. 1 supplemen- ted with 0,250,500 ,or 1,000 P-＇rU phytase per kg of diet. Six cages containing five chicks were allotted to each of the four treatments. In Exp. 1, there was no difference in weight gain, feed intake or feed conver- sion as a result of feeding the different sources of in- organic phosphorus. The digestibility of phosphorus was significantly lower （P =0.01 ） for chicks fed di- ets supplemented with tricalcium phosphate than for chicks fed the other two diets. However, despite the lower digestibility, serum phosphorus levels did not differ among the three treatments. For Exp. 2, feedconversion showed a linear improvement （P = 0.03 ） with increasing levels of phytase inclusion （ days 0 to 33 ）. Phytase supplementation resulted in linear increa- ses in the digestibility of dry matter （P = 0.02 ）, crude protein （ P --- 0.04 ） and energy （ P 〈 0.01 ）. Chicks fed 1,000 FTU/kg phytase had significantly higher bone calcium （ P = 0.05 ） and bone breaking strength （P = 0.04 ） than chicks fed the basal diet on day 33. In conclusion, the results of the current study indicated that the performance of birds fed diets sup- plemented with dicalcium phosphate, tricalcium phos- phate or defluorinated phosphate was similar and therefore production costs could be lowered by choo- sing the cheapest inorganic phosphorus source when formulating diets for poultry. When diets were formu- lated to meet dietary phosphorus requirements, the gr
基金supported by the National Key R&D Program of China under Contract No.2022YFA1602200the International Partnership Program of the Chineses Academy of Sciences under Grant No.211134KYSB20200057the STCF Key Technology Research and Development Project.
文摘The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or higher.The STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard Model.The STCF project in China is under development with an extensive R&D program.This document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.
基金Supported in part by the National Key R&D Program of China(2020YFA0406300,2020YFA0406400)the National Natural Science Foundation of China(NSFC)(11625523,11635010,11735014,11835012,11935015,11935016,11935018,11961141012,12025502,12035009,12035013,12061131003,12105276,12122509,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017)+15 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U1732263,U1832103,U1832207,U2032111)CAS Key Research Program of Frontier Sciences(QYZDJ-SSW-SLH003,QYZDJ-SSW-SLH040)100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and CosmologyEuropean Union's Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement(894790)German Research Foundation DFG(455635585),Collaborative Research Center CRC 1044,FOR5327,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF-2022R1A2C1092335)National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation of Thailand(B16F640076)Polish National Science Centre(2019/35/O/ST2/02907)The Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374)。
文摘Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both channels.With the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,respectively.The branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,respectively.The amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.
基金Supported in part by the National Key R&D Program of China(2020YFA0406400,2020YFA0406300,2023YFA1606000)the National Natural Science Foundation of China(123B2077,12035009,11635010,11735014,11875054,11935015,11935016,11935018,11961141012,12025502,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017,12361141819)+8 种基金the Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Program,the CAS Center for Excellence in Particle Physics(CCEPP),the Joint Large-Scale Scientific Facility Funds of the NSFC and CAS(U2032104,U1832207)the Excellent Youth Foundation of Henan Scientific Commitee(242300421044)100 Talents Program of CASthe Institute of Nuclear and Particle Physics(INPAC)and Shanghai Key Laboratory for Particle Physics and Cosmology,German Research Foundation DFG(455635585,FOR5327,GRK 2149)Istituto Nazionale di Fisica Nucleare,Italy,Ministry of Development of Turkey(DPT2006K-120470)National Research Foundation of Korea(NRF-2022R1A2C1092335)National Science and Technology fund of Mongolia,National Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation of Thailand(B16F640076)Polish National Science Centre(2019/35/O/ST2/02907),the Swedish Research CouncilU.S.Department of Energy(DE-FG02-05ER41374)。
文摘We present a measurement of the integrated luminosity of e^(+)e^(-)collision data collected by the BESIII detector at the BEPCII collider at a center-of-mass energy of Ecm=3.773 GeV.The integrated luminosities of the datasets taken from December 2021 to June 2022,from November 2022 to June 2023,and from October 2023 to February 2024 were determined to be 4.995±0.019 fb^(-1),8.157±0.031 fb^(-1),and 4.191±0.016 fb^(-1),respectively,by analyzing large angle Bhabha scattering events.The uncertainties are dominated by systematic effects,and the statistical uncertainties are negligible.Our results provide essential input for future analyses and precision measurements.
基金supported in part by National Key R&D Program of China under Contracts Nos.2020YFA0406300,2020YFA0406400National Natural Science Foundation of China(NSFC)under Contracts Nos.12150004,11635010,11735014,11835012,11935015,11935016,11935018,11961141012,12025502,12035009,12035013,12061131003,12192260,12192261,12192262,12192263,12192264,12192265,12221005,12225509,12235017+17 种基金the Program of Science and Technology Development Plan of Jilin Province of China under Contract Nos.20210508047RQ and 20230101021JCthe Chinese Academy of Sciences(CAS)Large-Scale Scientific Facility Programthe CAS Center for Excellence in Particle Physics(CCEPP)Joint Large-Scale Scientific Facility Funds of the NSFC and CAS under Contract No.U1832207CAS Key Research Program of Frontier Sciences under Contracts Nos.QYZDJ-SSW-SLH003,QYZDJ-SSW-SLH040100 Talents Program of CASThe Institute of Nuclear and Particle Physics(INPAC)Shanghai Key Laboratory for Particle Physics and CosmologyEuropean Union's Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement under Contract No.894790German Research Foundation DFG under Contracts Nos.455635585,Collaborative Research Center CRC 1044,FOR5327,GRK 2149Istituto Nazionale di Fisica Nucleare,ItalyMinistry of Development of Turkey under Contract No.DPT2006K-120470National Research Foundation of Korea under Contract No.NRF-2022R1A2C1092335National Science and Technology fund of MongoliaNational Science Research and Innovation Fund(NSRF)via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation of Thailand under Contract No.B16F640076Polish National Science Centre under Contract No.2019/35/O/ST2/02907The Swedish Research CouncilU.S.Department of Energy under Contract No.DE-FG02-05ER41374。
文摘The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic events.The uncertainty is systematic and the statistical uncertainty is negligible.Meanwhile,the numbers ofψ(3686)events collected during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,respectively.Both numbers are consistent with the previous measurements within one standard deviation.The total number ofψ(3686)events in the three data samples is(2712.4±14.3)×10~6.
