Background:Weight gain during pregnancy reflects the mother's nutritional status.However, it may be affected by nutritional therapy and exercise interventions used to control blood sugar in gestational diabetes me...Background:Weight gain during pregnancy reflects the mother's nutritional status.However, it may be affected by nutritional therapy and exercise interventions used to control blood sugar in gestational diabetes mellitus (GDM).This study aimed to evaluate weight gain during gestation and pregnancy outcomes among women with GDM.Methods:A retrospective study involving 1523 women with GDM was conducted between July 2013 and July 2016.Demographic data, gestational weight gain (GWG), blood glucose, glycated-hemoglobin level, and maternal and fetal outcomes were extracted from medical records.Relationships between GWG and pregnancy outcomes were investigated using multivariate logistic regression.Results:In total, 451 (29.6%) women showed insufficient GWG and 484 (31.8%) showed excessive GWG.Excessive GWG was independently associated with macrosomia (adjusted odds ratio [aOR] 2.20, 95% confidence interval [CI] 1.50-3.52, P<0.001), large for gestational age (aOR 2.06, 95% CI 1.44-2.93, P<0.001), small for gestational age (aOR 0.49, 95% CI 0.25-0.97, P=0.040), neonatal hypoglycemia (aOR 3.80, 95% CI 1.20-12.00, P=0.023), preterm birth (aOR 0.45, 95% CI 0.21-0.96, P=0.040), and cesarean delivery (aOR 1.45, 95% CI 1.13-1.87, P=0.004).Insufficient GWG increased the incidence of preterm birth (aOR 3.53, 95% CI 1.96-6.37, P<0.001).Conclusions:Both excessive and insufficient weight gain require attention in women with GDM.Nutritional therapy and exercise interventions to control blood glucose should also be used to control reasonable weight gain during pregnancy to decrease adverse pregnancy outcomes.展开更多
Internet has become a major medium for infomation transmission, how to detect hot topic on web, track the event development and forecast emergency is important to many fields, particularly to some government departmen...Internet has become a major medium for infomation transmission, how to detect hot topic on web, track the event development and forecast emergency is important to many fields, particularly to some government departments. On the basis of the researches in the field of topic detection and tracking, we propose a model for hot topic discovery that will pick out hot topics by automatically detecting, clustering and weighting topics on the websites within a time period. Based on the idea of stock index, we also introduce a topic index approach in following the growth of topics, which is useful to analyze and forecast the development of topics on web.展开更多
Background Bronchial anthracofibrosis （BAF） has been defined as a luminal narrowing associated with anthracotic pigmentation on bronchoscopy without a relevant history of pneumoconiosis or smoking. The aim of the st...Background Bronchial anthracofibrosis （BAF） has been defined as a luminal narrowing associated with anthracotic pigmentation on bronchoscopy without a relevant history of pneumoconiosis or smoking. The aim of the study is to study the clinical features and imaging manifestations of BAF, and to promote the awareness of this disease. Method Between October 2006 and January 2012, 15 patients were diagnosed at our department as BAF that showed a narrowing or obliteration of lobar or segmental bronchi with anthracotic pigmentation in the overlying mucosa on bronchoscopy. The medical records including clinical features, imaging manifestations, electronic bronchoscopic findings, and pathological features were analysed, and the literature was reviewed. Results A total of 15 patients were analyzed; 13 were female （86.7%） and two were male （13.3%） and the age range was from 62 to 86 years with a mean age of 74.5 years. Three cases （20.0%） had a history of tuberculosis. The most common clinical symptoms of BAF were cough （100%）, expectoration （73.3%）, dyspnea （60.0%）, and fever （46.7%）. Twelve cases displayed mild to moderate obstructive ventilatory dysfunction. In the electronic bronchoscopic evaluation, the most common findings were black bronchial mucosal pigmentation, bronchial stenosis, bronchial occlusion, and bronchial mucosal folds. Pathological evaluation revealed chronic inflammation of the bronchial mucosa, submucosal carbon particle deposition, and mucosal or submucosal fibrosis. Chest CT scans showed that 15 patients had bronchial stenosis or obstruction （direct signs） with the right middle lobe being the most common site （11 cases, 73.3%）. The indirect sign was mainly the presence of bronchial obstructive diseases （including secondary infection）, represented by 11 cases of pulmonary consolidation （73.3%）, seven cases of atelectasis （46.7%）, and five cases of nodules （33.3%）. The CT mediastinal window showed bronchial lymph node lesions, mediastinal lymph 展开更多
【目的】土壤磷形态的组成和强度对提高作物磷的生物有效性和磷肥的利用效率具有重要的作用。研究磷肥用量对棉田土壤无机磷形态和数量的影响,为集约化棉花生产体系中磷肥合理施用提供技术基础。【方法】本文以新陆早57号、新陆早50号...【目的】土壤磷形态的组成和强度对提高作物磷的生物有效性和磷肥的利用效率具有重要的作用。研究磷肥用量对棉田土壤无机磷形态和数量的影响,为集约化棉花生产体系中磷肥合理施用提供技术基础。【方法】本文以新陆早57号、新陆早50号和新陆早13号为研究对象,设置4个不同供磷水平[0 kg/hm^2(P0)、75 kg/hm^2(P75)、150 kg/hm^2(P150)、400 kg/hm^2(P400)],在棉花磷素营养关键的苗期和花铃期测定不同土层土壤无机磷含量。【结果】与对照(P0)相比,低量施磷(P75)下,苗期根层(0~20 cm土层)土壤Ca2-P、Ca8-P、Ca(10)-P、Fe-P、Al-P分别平均增加了68.5%、42.0%、-17.6%、38.8%、60.5%,花铃期根层(0~20 cm土层)土壤Ca2-P、Ca8-P、Ca(10)-P、Fe-P、Al-P分别平均增加了52.8%、18.8%、-17.7%、38.3%、44.7%;适量施磷(P150)下,苗期分别平均增加了148.9%、88.1%、-31.5%、65.6%、46.7%,花铃期分别平均增加了113.7%、54.5%、29.4%、77.6%、27.7%;过量施磷(P400)下,苗期分别平均增加了58.6%、53.4%、44.4%、105.8%、32.8%,花铃期分别平均增加了52.3%、19.3%、40.8%、143.8%、13.7%。不同棉花品种的比较显示,不同供磷条件下,苗期土壤Ca8-P、Ca(10)-P、Fe-P以XLZ50较高,Ca2-P、Al-P以XLZ57较高;花铃期土壤Ca8-P、Ca(10)-P以XLZ50较高, Ca2-P、Fe-P、Al-P以XLZ57较高。【结论】不同施磷水平和不同基因型棉花对土壤无机磷的积累均有不同程度的影响,其中150 kg P2O5/hm^2处理下棉田苗期和花铃期各土层Ca2-P最高,XLZ57基因型棉花苗期和花铃期各土层Ca2-P在施磷75~150 kg P2O5/hm^2处理下显著高于XLZ50和XLZ13。因此,合理施用磷肥(150 kg P2O5/hm^2)和合理种植棉花品种(XLZ57)可提高土壤中的有效磷源,从而提高磷肥利用效率。展开更多
Background Spinocerebellar ataxia type 7 （SCA7） is known as an autosomal dominant cerebellar ataxia; patients with genetically confirmed diagnoses of SCA7 have increased rapidly in recent years.However, SCA7 is a ra...Background Spinocerebellar ataxia type 7 （SCA7） is known as an autosomal dominant cerebellar ataxia; patients with genetically confirmed diagnoses of SCA7 have increased rapidly in recent years.However, SCA7 is a rare subtype of SCA, and most data available about SCA7 are those of white people.The aim of the present study was to systematically review the prevalence and clinical and genetic aspects of SCA7 patients in East Asian population.Methods A search for publications on SCA7 was performed by using the ＂PubMed＂ database with the published language limited in English.Publications mainly focusing on the prevalence of SCA7 in patients with SCA and the clinical and genetic features of SCA7 patients were fully reviewed and analyzed.Results The prevalence of SCA7 in SCA patients ranged from 0 to 7.7%, which was similar to those reported previously.The clinical manifestations were typically present at the 30＇s of its victims （median, 29 years; interquartile range （IQR）,19.5-36.5 years）, and the symptoms appeared 15 years （（15.17±4.22） years） earlier on average in the offspring than in the parents.Gait ataxia and visual impairment were both found in all patients of whom the clinical features were described.Mutant SCA7 alleles contained 40-100 CAG repeats, with a median of 47 repeats （IQR, 44.5-50.0）; and the offspring had 13 more repeats on average compared with their parents （12.62±19.03）.A strong negative correlation was found between CAG repeat size and the onset age of patients （r=-0.739, P=0.000）.In addition, no significant difference was found in CAG repeat sizes between patients with visual impairment as the initial symptom and those with gait disturbance as their initial symptom （P=0.476）.Conclusions The prevalence of SCA7 in SCA patients, the age at onset and CAG repeats of SCA7 patients in East Asia are consistent with those of white people.However, larger population study is needed to assess the correlation between the CAG repeat size and initial symptoms of SCA7展开更多
文摘Background:Weight gain during pregnancy reflects the mother's nutritional status.However, it may be affected by nutritional therapy and exercise interventions used to control blood sugar in gestational diabetes mellitus (GDM).This study aimed to evaluate weight gain during gestation and pregnancy outcomes among women with GDM.Methods:A retrospective study involving 1523 women with GDM was conducted between July 2013 and July 2016.Demographic data, gestational weight gain (GWG), blood glucose, glycated-hemoglobin level, and maternal and fetal outcomes were extracted from medical records.Relationships between GWG and pregnancy outcomes were investigated using multivariate logistic regression.Results:In total, 451 (29.6%) women showed insufficient GWG and 484 (31.8%) showed excessive GWG.Excessive GWG was independently associated with macrosomia (adjusted odds ratio [aOR] 2.20, 95% confidence interval [CI] 1.50-3.52, P<0.001), large for gestational age (aOR 2.06, 95% CI 1.44-2.93, P<0.001), small for gestational age (aOR 0.49, 95% CI 0.25-0.97, P=0.040), neonatal hypoglycemia (aOR 3.80, 95% CI 1.20-12.00, P=0.023), preterm birth (aOR 0.45, 95% CI 0.21-0.96, P=0.040), and cesarean delivery (aOR 1.45, 95% CI 1.13-1.87, P=0.004).Insufficient GWG increased the incidence of preterm birth (aOR 3.53, 95% CI 1.96-6.37, P<0.001).Conclusions:Both excessive and insufficient weight gain require attention in women with GDM.Nutritional therapy and exercise interventions to control blood glucose should also be used to control reasonable weight gain during pregnancy to decrease adverse pregnancy outcomes.
文摘Internet has become a major medium for infomation transmission, how to detect hot topic on web, track the event development and forecast emergency is important to many fields, particularly to some government departments. On the basis of the researches in the field of topic detection and tracking, we propose a model for hot topic discovery that will pick out hot topics by automatically detecting, clustering and weighting topics on the websites within a time period. Based on the idea of stock index, we also introduce a topic index approach in following the growth of topics, which is useful to analyze and forecast the development of topics on web.
文摘Background Bronchial anthracofibrosis （BAF） has been defined as a luminal narrowing associated with anthracotic pigmentation on bronchoscopy without a relevant history of pneumoconiosis or smoking. The aim of the study is to study the clinical features and imaging manifestations of BAF, and to promote the awareness of this disease. Method Between October 2006 and January 2012, 15 patients were diagnosed at our department as BAF that showed a narrowing or obliteration of lobar or segmental bronchi with anthracotic pigmentation in the overlying mucosa on bronchoscopy. The medical records including clinical features, imaging manifestations, electronic bronchoscopic findings, and pathological features were analysed, and the literature was reviewed. Results A total of 15 patients were analyzed; 13 were female （86.7%） and two were male （13.3%） and the age range was from 62 to 86 years with a mean age of 74.5 years. Three cases （20.0%） had a history of tuberculosis. The most common clinical symptoms of BAF were cough （100%）, expectoration （73.3%）, dyspnea （60.0%）, and fever （46.7%）. Twelve cases displayed mild to moderate obstructive ventilatory dysfunction. In the electronic bronchoscopic evaluation, the most common findings were black bronchial mucosal pigmentation, bronchial stenosis, bronchial occlusion, and bronchial mucosal folds. Pathological evaluation revealed chronic inflammation of the bronchial mucosa, submucosal carbon particle deposition, and mucosal or submucosal fibrosis. Chest CT scans showed that 15 patients had bronchial stenosis or obstruction （direct signs） with the right middle lobe being the most common site （11 cases, 73.3%）. The indirect sign was mainly the presence of bronchial obstructive diseases （including secondary infection）, represented by 11 cases of pulmonary consolidation （73.3%）, seven cases of atelectasis （46.7%）, and five cases of nodules （33.3%）. The CT mediastinal window showed bronchial lymph node lesions, mediastinal lymph
文摘【目的】土壤磷形态的组成和强度对提高作物磷的生物有效性和磷肥的利用效率具有重要的作用。研究磷肥用量对棉田土壤无机磷形态和数量的影响,为集约化棉花生产体系中磷肥合理施用提供技术基础。【方法】本文以新陆早57号、新陆早50号和新陆早13号为研究对象,设置4个不同供磷水平[0 kg/hm^2(P0)、75 kg/hm^2(P75)、150 kg/hm^2(P150)、400 kg/hm^2(P400)],在棉花磷素营养关键的苗期和花铃期测定不同土层土壤无机磷含量。【结果】与对照(P0)相比,低量施磷(P75)下,苗期根层(0~20 cm土层)土壤Ca2-P、Ca8-P、Ca(10)-P、Fe-P、Al-P分别平均增加了68.5%、42.0%、-17.6%、38.8%、60.5%,花铃期根层(0~20 cm土层)土壤Ca2-P、Ca8-P、Ca(10)-P、Fe-P、Al-P分别平均增加了52.8%、18.8%、-17.7%、38.3%、44.7%;适量施磷(P150)下,苗期分别平均增加了148.9%、88.1%、-31.5%、65.6%、46.7%,花铃期分别平均增加了113.7%、54.5%、29.4%、77.6%、27.7%;过量施磷(P400)下,苗期分别平均增加了58.6%、53.4%、44.4%、105.8%、32.8%,花铃期分别平均增加了52.3%、19.3%、40.8%、143.8%、13.7%。不同棉花品种的比较显示,不同供磷条件下,苗期土壤Ca8-P、Ca(10)-P、Fe-P以XLZ50较高,Ca2-P、Al-P以XLZ57较高;花铃期土壤Ca8-P、Ca(10)-P以XLZ50较高, Ca2-P、Fe-P、Al-P以XLZ57较高。【结论】不同施磷水平和不同基因型棉花对土壤无机磷的积累均有不同程度的影响,其中150 kg P2O5/hm^2处理下棉田苗期和花铃期各土层Ca2-P最高,XLZ57基因型棉花苗期和花铃期各土层Ca2-P在施磷75~150 kg P2O5/hm^2处理下显著高于XLZ50和XLZ13。因此,合理施用磷肥(150 kg P2O5/hm^2)和合理种植棉花品种(XLZ57)可提高土壤中的有效磷源,从而提高磷肥利用效率。
文摘Background Spinocerebellar ataxia type 7 （SCA7） is known as an autosomal dominant cerebellar ataxia; patients with genetically confirmed diagnoses of SCA7 have increased rapidly in recent years.However, SCA7 is a rare subtype of SCA, and most data available about SCA7 are those of white people.The aim of the present study was to systematically review the prevalence and clinical and genetic aspects of SCA7 patients in East Asian population.Methods A search for publications on SCA7 was performed by using the ＂PubMed＂ database with the published language limited in English.Publications mainly focusing on the prevalence of SCA7 in patients with SCA and the clinical and genetic features of SCA7 patients were fully reviewed and analyzed.Results The prevalence of SCA7 in SCA patients ranged from 0 to 7.7%, which was similar to those reported previously.The clinical manifestations were typically present at the 30＇s of its victims （median, 29 years; interquartile range （IQR）,19.5-36.5 years）, and the symptoms appeared 15 years （（15.17±4.22） years） earlier on average in the offspring than in the parents.Gait ataxia and visual impairment were both found in all patients of whom the clinical features were described.Mutant SCA7 alleles contained 40-100 CAG repeats, with a median of 47 repeats （IQR, 44.5-50.0）; and the offspring had 13 more repeats on average compared with their parents （12.62±19.03）.A strong negative correlation was found between CAG repeat size and the onset age of patients （r=-0.739, P=0.000）.In addition, no significant difference was found in CAG repeat sizes between patients with visual impairment as the initial symptom and those with gait disturbance as their initial symptom （P=0.476）.Conclusions The prevalence of SCA7 in SCA patients, the age at onset and CAG repeats of SCA7 patients in East Asia are consistent with those of white people.However, larger population study is needed to assess the correlation between the CAG repeat size and initial symptoms of SCA7
