This study entailed the development of a high-gradient modulation of microbunching for traditional radiation frequency accelerators using a minimized system driven by a relativistic Laguerre–Gaussian(LG)laser in thre...This study entailed the development of a high-gradient modulation of microbunching for traditional radiation frequency accelerators using a minimized system driven by a relativistic Laguerre–Gaussian(LG)laser in three-dimensional particlein-cell(PIC)simulations.It was observed that the LG laser could compress the transverse dimension of the beam to within a 0.7μm radius(divergence≈4.3 mrad),which is considerably lower than the case tuned by a Gaussian laser.In addition,the electron beam could be efficiently modulated to a high degree of bunching effect(>0.5)within~21 fs(~7μm)in the longitudinal direction.Such a high-gradient density modulation driven by an LG laser for pre-bunched,low-divergence,and stable electron beams provides a potential technology for the system minimization of X-ray free-electron lasers(XFELs)and ultrashort-scale(attosecond)electron diffraction research.展开更多
Objective:To observe the effect of acupuncture and bloodletting therapy at the lumbosacral region for chronic prostatitis.Methods:A total of 36 patients with chronic prostatitis were collected,and treated in the Depar...Objective:To observe the effect of acupuncture and bloodletting therapy at the lumbosacral region for chronic prostatitis.Methods:A total of 36 patients with chronic prostatitis were collected,and treated in the Department of Acupuncture and Moxibustion and the External Treatment Center of Chinese Medicine,Affiliated Hospital of Shandong University of Traditional Chinese medicine.The patients were treated with acupuncture,combined with bloodletting therapy at the lumbosacral region.The treatment for 4 weeks was as one course and 2 consecutive courses of treatment were required.The therapeutic effect,including the score of the National Institute of Health-Chronic prostatitis symptom index(NIH-CPSI),was assessed.Results:After 1 and 2 courses of treatment,the symptom scores and NIH-CPSI total score were all reduced as compared with that before treatment,respectively(all P<0.01).After 2 courses of treatment,the score of each symptom and NIH-CPSI total score were reduced as compared with that after 1 course of treatment,respectively(all P<0.01).Regrading the 3 syndromes/patterns of chronic prostatitis in the patients,i.e.downward invasion of damp heat,qi and blood stagnation and liver qi stagnation,after 1 and 2 courses of treatment,NIH-CPSI total scores were all reduced as compared with that before treatment(all P<0.01).Additionally,after 2 courses of treatment,NIH-CPSI total score of each syndrome/pattern was reduced as compared with that after 1 course of treatment(all P<0.01).For kidney yin deficiency,after 2 courses of treatment,NIH-CPSI total score was reduced as compared with that either before treatment or after 1 course of treatment(both P<0.01).The total effective rate was 91.67%after 1 course of treatment and 97.22%after 2 courses of treatment.No obvious adverse events occurred during the treatment.Conclusion:The combined treatment with acupuncture and bloodletting therapy at the lumbosacral region effectively relieves the symptoms of chronic prostatitis and improves the quality of life in the patients.展开更多
Memristor chaotic systems have aroused great attention in recent years with their potentials expected in engineering applications.In this paper,a five-dimension(5D)double-memristor hyperchaotic system(DMHS)is modeled ...Memristor chaotic systems have aroused great attention in recent years with their potentials expected in engineering applications.In this paper,a five-dimension(5D)double-memristor hyperchaotic system(DMHS)is modeled by introducing two active magnetron memristor models into the Kolmogorov-type formula.The boundness condition of the proposed hyperchaotic system is proved.Coexisting bifurcation diagram and numerical verification explain the bistability.The rich dynamics of the system are demonstrated by the dynamic evolution map and the basin.The simulation results reveal the existence of transient hyperchaos and hidden extreme multistability in the presented DMHS.The NIST tests show that the generated signal sequence is highly random,which is feasible for encryption purposes.Furthermore,the system is implemented based on a FPGA experimental platform,which benefits the further applications of the proposed hyperchaos.展开更多
The utilization of thin plate systems based on acoustic vibration holds significant importance in micro-nano manipulation and the exploration of nonlinear science. This paper focuses on the analysis of an actual thin ...The utilization of thin plate systems based on acoustic vibration holds significant importance in micro-nano manipulation and the exploration of nonlinear science. This paper focuses on the analysis of an actual thin plate system driven by acoustic wave signals. By combining the mechanical analysis of thin plate microelements with the Bubnov–Galerkin integral method, the governing equation for the forced vibration of a square thin plate is derived. Notably,the reaction force of the thin plate vibration system is defined as f=α|w|, resembling Hooke’s law. The energy function and energy level curve of the system are also analyzed. Subsequently, the amplitude–frequency response function of the thin plate oscillator is solved using the harmonic balance method. Through numerical simulations, the amplitude–frequency curves are analyzed for different vibration modes under the influence of various parameters. Furthermore, the paper demonstrates the occurrence of conservative chaotic motions in the thin plate oscillator using theoretical and numerical methods. Dynamics maps illustrating the system’s states are presented to reveal the evolution laws of the system. By exploring the effects of force fields and system energy, the underlying mechanism of chaos is interpreted. Additionally, the phenomenon of chaos in the oscillator can be controlled through the method of velocity and displacement states feedback, which holds significance for engineering applications.展开更多
Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-...Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-time suppression method using two IMBs of similar frequencies from different combs.As the two IMBs obtain similar RPDs during their transmission through same signal paths,the RPD of the original probing signal IMB is suppressed by deducting the RPD of the newly added local IMB in real time.In our experiments,a real-time suppression of RPDs is achieved using IMBs of 1001 and 1000 MHz.For the sampling time of 100 s,the effect of 19-fold suppression has been achieved.The proposed method provides a new solution for the long-standing phase drift problem in laser ranging with comb IMBs.展开更多
The quantum anomalous Hall effect(QAHE) has special quantum properties that are ideal for possible future spintronic devices. However, the experimental realization is rather challenging due to its low Curie temperatur...The quantum anomalous Hall effect(QAHE) has special quantum properties that are ideal for possible future spintronic devices. However, the experimental realization is rather challenging due to its low Curie temperature and small non-trivial bandgap in two-dimensional(2D) materials. In this paper, we demonstrate through first-principles calculations that monolayer Co2Te material is a promising 2D candidate to realize QAHE in practice. Excitingly, through Monte Carlo simulations, it is found that the Curie temperature of single-layer Co2Te can reach 573 K. The band crossing at the Fermi level in monolayer Co2Te is opened when spin–orbit coupling is considered, which leads to QAHE with a sizable bandgap of Eg= 96 me V, characterized by the non-zero Chern number(C = 1) and a chiral edge state. Therefore, our findings not only enrich the study of quantum anomalous Hall effect, but also broaden the horizons of the spintronics and topological nanoelectronics applications.展开更多
The highly pathogenic influenza A virus subtype H5N1 spread throughout Asia since 2003, reached to Europe in 2005, and the Middle East, as well as Africa and caused a global concern for a potential pandemic threat las...The highly pathogenic influenza A virus subtype H5N1 spread throughout Asia since 2003, reached to Europe in 2005, and the Middle East, as well as Africa and caused a global concern for a potential pandemic threat last decade. A Clade 2.3.2 H5N1 virus became dominate in the Qinghai Lake region in 2009 with sporadic mammal cases of infection and transferred to Russia and Europe through wild migratory birds. Currently, HPAI H5N1 of clades 2.3.4, 2.3.2, and 7 are the dominant co-circulating H5N1 viruses in poultry in Asia. 2.3.2 Clade is dominant in wild birds through the world whereas there is no evident data about Clade 7 circulation in wild birds. We detected HPAI H5N1 virus of Clade 7.1 in Qinghai Lake, that closely related to Shanxi-like and Vietnam viruses co-circulating in poultry. This is the first report of Clade 7.1 H5N1 in wild birds. Based on phylogenetic analyses, the virus can be originated from Clade 7.1 virus gene pool that spread in Vietnam and Chinese poultry and could spread with migratory birds to Qinghai Lake. The Qinghai Lake continues to be significant hotspot for H5N1 surveillance since the regular outbreaks occurred there in wild birds and mammals. Based on these facts and findings, the related researchers should pay more attention to the Qinghai Lake basin as significant hotspot for H5N1 avian influenza surveillance since the regular H5N1 outbreaks occurred there in wild birds with sporadic mammal cases of infection.展开更多
Objective: To investigate the short-term efficacy of laparoscopic radical resection of right-sided colon cancer with two different surgeon positions and trocar placements. Methods: The data of 78 patients who underwen...Objective: To investigate the short-term efficacy of laparoscopic radical resection of right-sided colon cancer with two different surgeon positions and trocar placements. Methods: The data of 78 patients who underwent laparoscopic radical resection of right-sided colon cancer between January 2018 and August 2019 were retrospectively analysed. The surgical method was selected by the patients. The patients were divided into two groups according to the surgeons’ positioning habits and trocar placements. The group with the lead surgeon standing between the patient’s legs had 35 patients, and the group with the lead surgeon standing at the left side of the patient had 43 patients. The operation time, intraoperative blood loss, postoperative anal gas evacuation time, postoperative urinary catheter indwelling time, postoperative hospital stay, C-reactive protein (CRP) level on the first day after surgery, and postoperative pathological data and complications were compared between the two groups. Results: All patients underwent the laparoscopic radical resection of right-sided colon cancer, none converting to laparotomy. No significant difference (P > 0.05) in intraoperative blood loss (57.6 ± 21.3 ml vs 60.2 ± 35.3 ml), postoperative anal gas evacuation time (3.5 ± 1.1 d vs 3.8 ± 1.3 d), postoperative urinary catheter indwelling time (2.6 ± 1.3 d vs 2.4 ± 1.2 d), postoperative hospital stay (7.1 ± 1.8 d vs 7.5 ± 2.1 d), or CRP level on the first day after surgery (54.7 ± 9.6 mg/L vs 53.9 ± 8.2 mg/L) was detected between the two groups. The operation time was shorter in the group with the lead surgeon standing between the patient’s legs (185.2 ± 25.6 min vs 196.2 ±19.7 min) (P < 0.05). The two groups did not differ significantly in the tumour length (4.2 ± 1.3 cm vs 3.9 ± 1.5 cm), number of dissected lymph nodes (27.5 ± 11.6 vs 25.1 ± 15.4), pathological type, or postoperative pathological tumour-node-metastasis stage (P > 0.05). No patients died or had anastomotic fistula during their postoperativ展开更多
We propose a new family of 3D Dirac semimetals based on XAuTe(X = K, Na, Rb) ternary honeycomb compounds, determined based on first-principles calculations, which are shown to be topological Dirac semimetals in which ...We propose a new family of 3D Dirac semimetals based on XAuTe(X = K, Na, Rb) ternary honeycomb compounds, determined based on first-principles calculations, which are shown to be topological Dirac semimetals in which the Dirac points are induced by band inversion. Dirac points with four-fold degeneracy that are protected by C3 rotation symmetry and located on the Γ-A high-symmetry path are found. Through spatial-inversion symmetry breaking, a K(Au0.5 Hg0.5)(Te0.5As0.5) superlattice structure composed of KHgAs and KAuTe compounds is proven to be a Weyl semimetal with type-II Weyl points, which connect electronand hole-like bands. In this superlattice structure, the six pairs of Weyl nodes are distributed along the K-Γ high-symmetry path on the kz = 0 plane. Our research expands the family of topological Dirac and type-II Weyl semimetals.展开更多
基金supported by the National Natural Science Foundation of China(No.12075306)the Natural Science Foundation of Shanghai(No.22ZR1470900)Key Research Programs in Frontier Science(No.ZDBS-LY-SLH006)。
文摘This study entailed the development of a high-gradient modulation of microbunching for traditional radiation frequency accelerators using a minimized system driven by a relativistic Laguerre–Gaussian(LG)laser in three-dimensional particlein-cell(PIC)simulations.It was observed that the LG laser could compress the transverse dimension of the beam to within a 0.7μm radius(divergence≈4.3 mrad),which is considerably lower than the case tuned by a Gaussian laser.In addition,the electron beam could be efficiently modulated to a high degree of bunching effect(>0.5)within~21 fs(~7μm)in the longitudinal direction.Such a high-gradient density modulation driven by an LG laser for pre-bunched,low-divergence,and stable electron beams provides a potential technology for the system minimization of X-ray free-electron lasers(XFELs)and ultrashort-scale(attosecond)electron diffraction research.
基金Supported by Shandong Special Project of High-Level Personnel Training of Traditional Chinese Medicine,Shandong Health Leading Talent Cultivation Special Program。
文摘Objective:To observe the effect of acupuncture and bloodletting therapy at the lumbosacral region for chronic prostatitis.Methods:A total of 36 patients with chronic prostatitis were collected,and treated in the Department of Acupuncture and Moxibustion and the External Treatment Center of Chinese Medicine,Affiliated Hospital of Shandong University of Traditional Chinese medicine.The patients were treated with acupuncture,combined with bloodletting therapy at the lumbosacral region.The treatment for 4 weeks was as one course and 2 consecutive courses of treatment were required.The therapeutic effect,including the score of the National Institute of Health-Chronic prostatitis symptom index(NIH-CPSI),was assessed.Results:After 1 and 2 courses of treatment,the symptom scores and NIH-CPSI total score were all reduced as compared with that before treatment,respectively(all P<0.01).After 2 courses of treatment,the score of each symptom and NIH-CPSI total score were reduced as compared with that after 1 course of treatment,respectively(all P<0.01).Regrading the 3 syndromes/patterns of chronic prostatitis in the patients,i.e.downward invasion of damp heat,qi and blood stagnation and liver qi stagnation,after 1 and 2 courses of treatment,NIH-CPSI total scores were all reduced as compared with that before treatment(all P<0.01).Additionally,after 2 courses of treatment,NIH-CPSI total score of each syndrome/pattern was reduced as compared with that after 1 course of treatment(all P<0.01).For kidney yin deficiency,after 2 courses of treatment,NIH-CPSI total score was reduced as compared with that either before treatment or after 1 course of treatment(both P<0.01).The total effective rate was 91.67%after 1 course of treatment and 97.22%after 2 courses of treatment.No obvious adverse events occurred during the treatment.Conclusion:The combined treatment with acupuncture and bloodletting therapy at the lumbosacral region effectively relieves the symptoms of chronic prostatitis and improves the quality of life in the patients.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.62003177,61973172,61973175,and 62073177)the key Technologies Research and Tianjin Natural Science Foundation (Grant No.19JCZDJC32800)+1 种基金China Postdoctoral Science Foundation (Grant Nos.2020M670633 and 2020M670045)Academy of Finland (Grant No.315660)。
文摘Memristor chaotic systems have aroused great attention in recent years with their potentials expected in engineering applications.In this paper,a five-dimension(5D)double-memristor hyperchaotic system(DMHS)is modeled by introducing two active magnetron memristor models into the Kolmogorov-type formula.The boundness condition of the proposed hyperchaotic system is proved.Coexisting bifurcation diagram and numerical verification explain the bistability.The rich dynamics of the system are demonstrated by the dynamic evolution map and the basin.The simulation results reveal the existence of transient hyperchaos and hidden extreme multistability in the presented DMHS.The NIST tests show that the generated signal sequence is highly random,which is feasible for encryption purposes.Furthermore,the system is implemented based on a FPGA experimental platform,which benefits the further applications of the proposed hyperchaos.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 61973172, 62003177, 62103204, 62003175, and 61973175)the Joint Fund of the Ministry of Education for Equipment Pre-research (Grant No. 8091B022133)General Terminal IC Interdisciplinary Science Center of Nankai University。
文摘The utilization of thin plate systems based on acoustic vibration holds significant importance in micro-nano manipulation and the exploration of nonlinear science. This paper focuses on the analysis of an actual thin plate system driven by acoustic wave signals. By combining the mechanical analysis of thin plate microelements with the Bubnov–Galerkin integral method, the governing equation for the forced vibration of a square thin plate is derived. Notably,the reaction force of the thin plate vibration system is defined as f=α|w|, resembling Hooke’s law. The energy function and energy level curve of the system are also analyzed. Subsequently, the amplitude–frequency response function of the thin plate oscillator is solved using the harmonic balance method. Through numerical simulations, the amplitude–frequency curves are analyzed for different vibration modes under the influence of various parameters. Furthermore, the paper demonstrates the occurrence of conservative chaotic motions in the thin plate oscillator using theoretical and numerical methods. Dynamics maps illustrating the system’s states are presented to reveal the evolution laws of the system. By exploring the effects of force fields and system energy, the underlying mechanism of chaos is interpreted. Additionally, the phenomenon of chaos in the oscillator can be controlled through the method of velocity and displacement states feedback, which holds significance for engineering applications.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.52175501 and 51605120)the Heilongjiang Provincial Natural Science Foundation(No.LH2021E059)the National Key Research and Development Program of China(No.2020YFC2200204)。
文摘Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-time suppression method using two IMBs of similar frequencies from different combs.As the two IMBs obtain similar RPDs during their transmission through same signal paths,the RPD of the original probing signal IMB is suppressed by deducting the RPD of the newly added local IMB in real time.In our experiments,a real-time suppression of RPDs is achieved using IMBs of 1001 and 1000 MHz.For the sampling time of 100 s,the effect of 19-fold suppression has been achieved.The proposed method provides a new solution for the long-standing phase drift problem in laser ranging with comb IMBs.
基金financially supported by the Science and Technology Commission of Shanghai Municipality(20501130200)the National Natural Science Foundation of China(51402342 and 61775201)the National Defense Technology Innovation Special Zone Project.
基金supported by the Taishan Scholar Program of Shandong Province, China (Grant No. ts20190939)the Independent Cultivation Program of Innovation Team of Jinan City (Grant No. 2021GXRC043)the National Natural Science Foundation of China (Grant No. 52173238)。
文摘The quantum anomalous Hall effect(QAHE) has special quantum properties that are ideal for possible future spintronic devices. However, the experimental realization is rather challenging due to its low Curie temperature and small non-trivial bandgap in two-dimensional(2D) materials. In this paper, we demonstrate through first-principles calculations that monolayer Co2Te material is a promising 2D candidate to realize QAHE in practice. Excitingly, through Monte Carlo simulations, it is found that the Curie temperature of single-layer Co2Te can reach 573 K. The band crossing at the Fermi level in monolayer Co2Te is opened when spin–orbit coupling is considered, which leads to QAHE with a sizable bandgap of Eg= 96 me V, characterized by the non-zero Chern number(C = 1) and a chiral edge state. Therefore, our findings not only enrich the study of quantum anomalous Hall effect, but also broaden the horizons of the spintronics and topological nanoelectronics applications.
文摘The highly pathogenic influenza A virus subtype H5N1 spread throughout Asia since 2003, reached to Europe in 2005, and the Middle East, as well as Africa and caused a global concern for a potential pandemic threat last decade. A Clade 2.3.2 H5N1 virus became dominate in the Qinghai Lake region in 2009 with sporadic mammal cases of infection and transferred to Russia and Europe through wild migratory birds. Currently, HPAI H5N1 of clades 2.3.4, 2.3.2, and 7 are the dominant co-circulating H5N1 viruses in poultry in Asia. 2.3.2 Clade is dominant in wild birds through the world whereas there is no evident data about Clade 7 circulation in wild birds. We detected HPAI H5N1 virus of Clade 7.1 in Qinghai Lake, that closely related to Shanxi-like and Vietnam viruses co-circulating in poultry. This is the first report of Clade 7.1 H5N1 in wild birds. Based on phylogenetic analyses, the virus can be originated from Clade 7.1 virus gene pool that spread in Vietnam and Chinese poultry and could spread with migratory birds to Qinghai Lake. The Qinghai Lake continues to be significant hotspot for H5N1 surveillance since the regular outbreaks occurred there in wild birds and mammals. Based on these facts and findings, the related researchers should pay more attention to the Qinghai Lake basin as significant hotspot for H5N1 avian influenza surveillance since the regular H5N1 outbreaks occurred there in wild birds with sporadic mammal cases of infection.
文摘Objective: To investigate the short-term efficacy of laparoscopic radical resection of right-sided colon cancer with two different surgeon positions and trocar placements. Methods: The data of 78 patients who underwent laparoscopic radical resection of right-sided colon cancer between January 2018 and August 2019 were retrospectively analysed. The surgical method was selected by the patients. The patients were divided into two groups according to the surgeons’ positioning habits and trocar placements. The group with the lead surgeon standing between the patient’s legs had 35 patients, and the group with the lead surgeon standing at the left side of the patient had 43 patients. The operation time, intraoperative blood loss, postoperative anal gas evacuation time, postoperative urinary catheter indwelling time, postoperative hospital stay, C-reactive protein (CRP) level on the first day after surgery, and postoperative pathological data and complications were compared between the two groups. Results: All patients underwent the laparoscopic radical resection of right-sided colon cancer, none converting to laparotomy. No significant difference (P > 0.05) in intraoperative blood loss (57.6 ± 21.3 ml vs 60.2 ± 35.3 ml), postoperative anal gas evacuation time (3.5 ± 1.1 d vs 3.8 ± 1.3 d), postoperative urinary catheter indwelling time (2.6 ± 1.3 d vs 2.4 ± 1.2 d), postoperative hospital stay (7.1 ± 1.8 d vs 7.5 ± 2.1 d), or CRP level on the first day after surgery (54.7 ± 9.6 mg/L vs 53.9 ± 8.2 mg/L) was detected between the two groups. The operation time was shorter in the group with the lead surgeon standing between the patient’s legs (185.2 ± 25.6 min vs 196.2 ±19.7 min) (P < 0.05). The two groups did not differ significantly in the tumour length (4.2 ± 1.3 cm vs 3.9 ± 1.5 cm), number of dissected lymph nodes (27.5 ± 11.6 vs 25.1 ± 15.4), pathological type, or postoperative pathological tumour-node-metastasis stage (P > 0.05). No patients died or had anastomotic fistula during their postoperativ
基金supported by the National Natual Science Foundation of China (Grant Nos. 21373190, 11322434 and 21421063)sponsored by the DOE Office of Biological and Environmental Research
文摘We propose a new family of 3D Dirac semimetals based on XAuTe(X = K, Na, Rb) ternary honeycomb compounds, determined based on first-principles calculations, which are shown to be topological Dirac semimetals in which the Dirac points are induced by band inversion. Dirac points with four-fold degeneracy that are protected by C3 rotation symmetry and located on the Γ-A high-symmetry path are found. Through spatial-inversion symmetry breaking, a K(Au0.5 Hg0.5)(Te0.5As0.5) superlattice structure composed of KHgAs and KAuTe compounds is proven to be a Weyl semimetal with type-II Weyl points, which connect electronand hole-like bands. In this superlattice structure, the six pairs of Weyl nodes are distributed along the K-Γ high-symmetry path on the kz = 0 plane. Our research expands the family of topological Dirac and type-II Weyl semimetals.
