The horizontal single belt casting(HSBC)incorporating a single-impingement feeding system was simulated with an improved numerical model.Physical experiments were carried out on the pilot-scale caster for validation.T...The horizontal single belt casting(HSBC)incorporating a single-impingement feeding system was simulated with an improved numerical model.Physical experiments were carried out on the pilot-scale caster for validation.The results show that the meniscus turbulence neither comes from the tundish region,nor from the impingement between the melt and the moving belt.It is the moving belt that gives rise to this high turbulence region,and this region can stir the melt near the meniscus.The feeding system studied and the moving belt give rise to a buffer region,which can optimize casting parameter variations,especially melt depth changes in the tundish.The temperature change rate of the bottom surface of the strip is around 4 times faster than that of the upper surface.展开更多
Consideration is given here to colour removal, carried out using immobilised biological cells, Shewanella strain J18 143. In order to provide greater control of an overall colour removal process and to give a basis fo...Consideration is given here to colour removal, carried out using immobilised biological cells, Shewanella strain J18 143. In order to provide greater control of an overall colour removal process and to give a basis for the effective recovery of the cell culture species, cell immobilisation has been established on chemically modified cellulose. The modification was achieved by chemically inducing the graft copolymerisation of methacrylic acid onto cotton fabric. The immobilised cells were able to decolorise the dye. The immobilisation methods, physical adsorption, “growing-in” and chemical coupling, were compared. Each of the methods was effective to some extent. However, the latter two immobilisation methods provided the greater effect in decoloration. Each of these immobilised systems is relatively simple to achieve, whether by adsorption, physical interlocking or covalent coupling. The graft copolymer is able to offer versatility in use. The decoloration was shown to be rapid under relatively simple processing conditions. Thus, compared with the established controls, complete decoloration of solutions of Remazol Black B was observed. The potential use of the graft copolymer substrate as support for a biochemical agent was confirmed.展开更多
Background:Six epidemic waves of human infection with avian influenza A (H7N9) virus have emerged in China with high mortality. However, study on quantitative relationship between clinical indices in ill persons and H...Background:Six epidemic waves of human infection with avian influenza A (H7N9) virus have emerged in China with high mortality. However, study on quantitative relationship between clinical indices in ill persons and H7N9 outcome (fatal and nonfatal) is still unclear. A retrospective cohort study was conducted to collect laboratory-confirmed cases with H7N9 viral infection from 2013 to 2015 in 23 hospitals across 13 cities in Guangdong Province, China.Methods:Multivariable logistic regression model and classification tree model analyses were used to detect the threshold of selected clinical indices and risk factors for H7N9 death. The receiver operating characteristic curve (ROC) and analyses were used to compare survival and death distributions and differences between indices. A total of 143 cases with 90 survivors and 53 deaths were investigated.Results:Average age (Odds Ratio (OR)=1.036, 95% Confidence Interval (CI)=1.016-1.057), interval days between dates of onset and confirmation (OR=1.078, 95% CI=1.004-1.157), interval days between onset and oseltamivir treatment (OR=5.923, 95% CI=1.877-18.687), body temperature (BT) (OR=3.612, 95% CI=1.914-6.815), white blood cell count (WBC) (OR=1.212, 95% CI=1.092-1.346) were significantly associated with H7N9 death after adjusting for confounders. The chance of death from H7N9 infection was 80.0% if BT was over 38.1 °C, and chance of death is 67.4% if WBC count was higher than 9.5 (109/L). Only 27.1% of patients who began oseltamivir treatment less than 9.5 days after disease onset died, compared to 68.8% of those who started treatment more than 15.5 days after onset.Conclusions:The intervals between date of onset and confirmation of diagnosis, between date of onset to oseltamivir treatment, age, BT and WBC are found to be the best predictors of H7N9 mortality.展开更多
快速回顾：IIS如何映射应用程序和站点？
Microsoft IIS支持在一个服务器上寄宿多个“站点”。这些站点被定义为一个由IP地址、主机名和／或端口地址惟一确定的组合。例如，我的站点（www．scottqu．tom）是由一个IP地址（192．197．15...快速回顾：IIS如何映射应用程序和站点？
Microsoft IIS支持在一个服务器上寄宿多个“站点”。这些站点被定义为一个由IP地址、主机名和／或端口地址惟一确定的组合。例如，我的站点（www．scottqu．tom）是由一个IP地址（192．197．157．24）、主机名（www．Scottgu．com）和端口号“80”（默认的HTTP端口）所组成的。Nikhil的站点（www．nikhilk．net）是另一个寄宿在同——Web服务器上的站点。它具有与我的站点相同的IP地址（192．197．257．24）和端口号（80），但是它的绑定主机名小同。只要这3个（IP地址、主机名、端口号）元素中有任何一个不同，那么就可以将在IIS上的每个站点区分开来并分别映射。展开更多
Background/Purpose: The aim of this paper was to investigate the mechanism of long-term biliary drainage after Kasai portoenterostomy by clinicopathologic study of hepatic morphology in explanted livers.Methods: Expla...Background/Purpose: The aim of this paper was to investigate the mechanism of long-term biliary drainage after Kasai portoenterostomy by clinicopathologic study of hepatic morphology in explanted livers.Methods: Explanted livers from 13 consecutive children undergoing transplantation for biliary atresia were examined in detail using a standardized protocol.Group 1 (n = 6) had no Kasai procedure before transplantation at a median age of 8 m.Group 2 (n = 4) were transplanted at a median age of 10 m after a failed Kasai portoenterostomy.Group 3 (n = 3) had a successful Kasai but required transplantation for complications of chronic liver disease at 12-14 years.Pathology findings were correlated with hepatic morphology determined by pretransplant magnetic resonance imaging.Results: Large perihilar regenerative nodules (8-14 cm diameter) were observed in 2 patients after successful Kasai portoenterostomy, less well-de-fined perihilar nodules in group 2 patients, and no regenerative nodules in group 1.Microscopically, group 1 had diffuse biliary cirrhosis with evidence of progressive ductopenia during infancy.In group 2, perihilar regenerative nodules showed variable portal fibrosis but no cirrhosis and bile ducts were present with 68%-100%of hepatic arteries; in peripheral cirrhotic areas, bile ducts were absent in patients older than 9 m.The perihilar regenerative nodules in group 3 patients had a noncirrhotic architecture with preserved bile ducts, but the peripheral parenchyma was cirrhotic; one patient had diffuse macronodular cirrhosis.These morphologic findings correlated well with magnetic resonance images, highlighting the preservation of relatively normal perihilar liver architecture after successful Kasai portoenterostomy.Conclusions: Unoperated biliary atresia is associated with progressive intrahepatic ductopenia leading to diffuse biliary cirrhosis.Kasai portoenterostomy can result in the growth of large perihilar regenerative nodules, probably as a consequence of surviving intrahepatic ducts in this regi展开更多
New heteroleptic lanthanide complex [L1ILaN{Si(CH3)2}] (1) containing tridentate [ONO] ancillary ligand was synthesized from an acid-base ligand exchange reaction with ligands H2L1 and corresponding homoleptic lanthan...New heteroleptic lanthanide complex [L1ILaN{Si(CH3)2}] (1) containing tridentate [ONO] ancillary ligand was synthesized from an acid-base ligand exchange reaction with ligands H2L1 and corresponding homoleptic lanthanide compound La[N{Si(CH3)3}2]3. Meanwhile, dimeric complexes [L1LaCl] (2) and [L1ILaCl] (3) were prepared from salt metathesis reaction between one equivalent of ligands H2LI,II, three equivalent of NaN{Si(CH3)3}2, and one equivalent of LaCl3. These compounds were characterized by nuclear magnetic resonance (300 MHz) and elemental analysis. These complexes were used as catalysts in the ring-opening homopolymerization of α-methylene-γ-butyrolactone. While compound 1 did not show any significant reactivity, compounds 2 and 3 gave significant amount of highly branched poly(α-methylene-γ-butyrolactone) as confirmed by 1H NMR spectroscopy and Malvern’s triple detector GPCMax analysis in DMSO with molecular weights of over 500,000 Dalton. The glass-transition temperatures of the branched polymer samples were determined using a Dynamic Mechanical Analyzer, DMA Q800.展开更多
基金financial support received from the research grant of Shandong University of Technology (4041/419099)the Natural Sciences and Engineering Research Council of Canada (NSERC)the International Advisory Board of Supporting Companies of the McGill Metals Processing Centre (MMPC).
文摘The horizontal single belt casting(HSBC)incorporating a single-impingement feeding system was simulated with an improved numerical model.Physical experiments were carried out on the pilot-scale caster for validation.The results show that the meniscus turbulence neither comes from the tundish region,nor from the impingement between the melt and the moving belt.It is the moving belt that gives rise to this high turbulence region,and this region can stir the melt near the meniscus.The feeding system studied and the moving belt give rise to a buffer region,which can optimize casting parameter variations,especially melt depth changes in the tundish.The temperature change rate of the bottom surface of the strip is around 4 times faster than that of the upper surface.
文摘Consideration is given here to colour removal, carried out using immobilised biological cells, Shewanella strain J18 143. In order to provide greater control of an overall colour removal process and to give a basis for the effective recovery of the cell culture species, cell immobilisation has been established on chemically modified cellulose. The modification was achieved by chemically inducing the graft copolymerisation of methacrylic acid onto cotton fabric. The immobilised cells were able to decolorise the dye. The immobilisation methods, physical adsorption, “growing-in” and chemical coupling, were compared. Each of the methods was effective to some extent. However, the latter two immobilisation methods provided the greater effect in decoloration. Each of these immobilised systems is relatively simple to achieve, whether by adsorption, physical interlocking or covalent coupling. The graft copolymer is able to offer versatility in use. The decoloration was shown to be rapid under relatively simple processing conditions. Thus, compared with the established controls, complete decoloration of solutions of Remazol Black B was observed. The potential use of the graft copolymer substrate as support for a biochemical agent was confirmed.
文摘Background:Six epidemic waves of human infection with avian influenza A (H7N9) virus have emerged in China with high mortality. However, study on quantitative relationship between clinical indices in ill persons and H7N9 outcome (fatal and nonfatal) is still unclear. A retrospective cohort study was conducted to collect laboratory-confirmed cases with H7N9 viral infection from 2013 to 2015 in 23 hospitals across 13 cities in Guangdong Province, China.Methods:Multivariable logistic regression model and classification tree model analyses were used to detect the threshold of selected clinical indices and risk factors for H7N9 death. The receiver operating characteristic curve (ROC) and analyses were used to compare survival and death distributions and differences between indices. A total of 143 cases with 90 survivors and 53 deaths were investigated.Results:Average age (Odds Ratio (OR)=1.036, 95% Confidence Interval (CI)=1.016-1.057), interval days between dates of onset and confirmation (OR=1.078, 95% CI=1.004-1.157), interval days between onset and oseltamivir treatment (OR=5.923, 95% CI=1.877-18.687), body temperature (BT) (OR=3.612, 95% CI=1.914-6.815), white blood cell count (WBC) (OR=1.212, 95% CI=1.092-1.346) were significantly associated with H7N9 death after adjusting for confounders. The chance of death from H7N9 infection was 80.0% if BT was over 38.1 °C, and chance of death is 67.4% if WBC count was higher than 9.5 (109/L). Only 27.1% of patients who began oseltamivir treatment less than 9.5 days after disease onset died, compared to 68.8% of those who started treatment more than 15.5 days after onset.Conclusions:The intervals between date of onset and confirmation of diagnosis, between date of onset to oseltamivir treatment, age, BT and WBC are found to be the best predictors of H7N9 mortality.
文摘快速回顾：IIS如何映射应用程序和站点？
Microsoft IIS支持在一个服务器上寄宿多个“站点”。这些站点被定义为一个由IP地址、主机名和／或端口地址惟一确定的组合。例如，我的站点（www．scottqu．tom）是由一个IP地址（192．197．157．24）、主机名（www．Scottgu．com）和端口号“80”（默认的HTTP端口）所组成的。Nikhil的站点（www．nikhilk．net）是另一个寄宿在同——Web服务器上的站点。它具有与我的站点相同的IP地址（192．197．257．24）和端口号（80），但是它的绑定主机名小同。只要这3个（IP地址、主机名、端口号）元素中有任何一个不同，那么就可以将在IIS上的每个站点区分开来并分别映射。
文摘Background/Purpose: The aim of this paper was to investigate the mechanism of long-term biliary drainage after Kasai portoenterostomy by clinicopathologic study of hepatic morphology in explanted livers.Methods: Explanted livers from 13 consecutive children undergoing transplantation for biliary atresia were examined in detail using a standardized protocol.Group 1 (n = 6) had no Kasai procedure before transplantation at a median age of 8 m.Group 2 (n = 4) were transplanted at a median age of 10 m after a failed Kasai portoenterostomy.Group 3 (n = 3) had a successful Kasai but required transplantation for complications of chronic liver disease at 12-14 years.Pathology findings were correlated with hepatic morphology determined by pretransplant magnetic resonance imaging.Results: Large perihilar regenerative nodules (8-14 cm diameter) were observed in 2 patients after successful Kasai portoenterostomy, less well-de-fined perihilar nodules in group 2 patients, and no regenerative nodules in group 1.Microscopically, group 1 had diffuse biliary cirrhosis with evidence of progressive ductopenia during infancy.In group 2, perihilar regenerative nodules showed variable portal fibrosis but no cirrhosis and bile ducts were present with 68%-100%of hepatic arteries; in peripheral cirrhotic areas, bile ducts were absent in patients older than 9 m.The perihilar regenerative nodules in group 3 patients had a noncirrhotic architecture with preserved bile ducts, but the peripheral parenchyma was cirrhotic; one patient had diffuse macronodular cirrhosis.These morphologic findings correlated well with magnetic resonance images, highlighting the preservation of relatively normal perihilar liver architecture after successful Kasai portoenterostomy.Conclusions: Unoperated biliary atresia is associated with progressive intrahepatic ductopenia leading to diffuse biliary cirrhosis.Kasai portoenterostomy can result in the growth of large perihilar regenerative nodules, probably as a consequence of surviving intrahepatic ducts in this regi
文摘New heteroleptic lanthanide complex [L1ILaN{Si(CH3)2}] (1) containing tridentate [ONO] ancillary ligand was synthesized from an acid-base ligand exchange reaction with ligands H2L1 and corresponding homoleptic lanthanide compound La[N{Si(CH3)3}2]3. Meanwhile, dimeric complexes [L1LaCl] (2) and [L1ILaCl] (3) were prepared from salt metathesis reaction between one equivalent of ligands H2LI,II, three equivalent of NaN{Si(CH3)3}2, and one equivalent of LaCl3. These compounds were characterized by nuclear magnetic resonance (300 MHz) and elemental analysis. These complexes were used as catalysts in the ring-opening homopolymerization of α-methylene-γ-butyrolactone. While compound 1 did not show any significant reactivity, compounds 2 and 3 gave significant amount of highly branched poly(α-methylene-γ-butyrolactone) as confirmed by 1H NMR spectroscopy and Malvern’s triple detector GPCMax analysis in DMSO with molecular weights of over 500,000 Dalton. The glass-transition temperatures of the branched polymer samples were determined using a Dynamic Mechanical Analyzer, DMA Q800.
