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Study on reservoir operation optimization of Ertan Hydropower Station considering GFS forecasted precipitation 被引量:9
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作者 PENG Yong 1,WANG GuoLi 1,TANG GuoLei 1,ZHOU HuiCheng 1,WANG YaJun 2 & JIAN DePing 2 1 Institute of Water Resources and flood Control,Dalian University of Technology,Dalian 116023,China 2 Ertan Hydropower Development Co.,Ltd.,Chengdu 610021,China 《Science China(Technological Sciences)》 SCIE EI CAS 2011年第S1期76-82,共7页
The medium-term runoff forecasting provided new information for forecast of medium and long term runoff and optimal hydroelectric power generation.According to the actual runoff and hydropower generating characteristi... The medium-term runoff forecasting provided new information for forecast of medium and long term runoff and optimal hydroelectric power generation.According to the actual runoff and hydropower generating characteristics of Ertan Hydropower Station,we studied the decade runoff quantitatively and grade forecast model based on Global Forecasting System(GFS) precipitation forecast information in wet season,then used the posteriori runoff transition probability and measurable probability of runoff forecast to research the uncertain runoff description based on runoff forecast;finally on the basis of the runoff description and the grading forecast accuracy of GFS-based next 10 days'total forecast precipitation,we studied the uncertain optimal operating model of Ertan Hydropower Station considering runoff forecast.The results showed that the runoff forecast considering GFS forecast precipitation and uncertainty has significantly improved the existing runoff description and operating optimization model,and obviously raised the hydropower generation efficiency of Ertan Reservoir. 展开更多
关键词 global forecasting system RUNOFF forecasting RUNOFF DESCRIPTION UNCERTAINTY optimal operation
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Comprehensive benefit of flood resources utilization through dynamic successive fuzzy evaluation model: A case study 被引量:7
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作者 FENG Feng1,2, XU ShiGuo1, LIU JianWei1, LIU Dan1,3 & WU Bo4 1 Institute of Water Environment, School of Civil and Hydraulic Engineering, Dalian University of Technology, Dalian 116024, China 2 Yellow River Conservancy Technical Institute, Kaifeng 475003, China +1 位作者 3 College of Water Resources, Shenyang Agricultural University, Shenyang 110161, China 4 Office of flood Control and Draught Relief in Jilin Province, Changchun 130033, China 《Science China(Technological Sciences)》 SCIE EI CAS 2010年第2期529-538,共10页
Taking the flood resources utilization in Baicheng, Jilin during 2002–2007 as the research background, and based on the entropy weight and multi-level & multi-objective fuzzy optimization theory, this research es... Taking the flood resources utilization in Baicheng, Jilin during 2002–2007 as the research background, and based on the entropy weight and multi-level & multi-objective fuzzy optimization theory, this research established a multi-level & semi-constructive index system and dynamic successive evaluation model for comprehensive benefit evaluation of regional flood resources utilization. With the year 2002 as the base year, the analyzing results showed that there existed a close positive correlation between flood utilization volume and its benefits, comprehensive evaluation value and its comparison increment. Within the six successive evaluation years, the comprehensive benefit of 2003 was the best, in which the benefit evaluation increment reached 82.8% whereas the year of 2004 was the worst, in which the increment was only 18.2%. Thus the sustainability and correctness of the evaluation were verified by six years successive evaluation and increment comparison. The analyzing results showed that the economic benefits, ecological benefits and social benefits of flood utilization were remarkable, and that the comprehensive benefit could be improved by increasing flood utilization capacity, which would promote the regional sustainable development as well. The established dynamic successive evaluation provides a stable theoretical basis and technical support for further flood utilization. 展开更多
关键词 FLOOD RESOURCES UTILIZATION COMPREHENSIVE BENEFIT DYNAMIC successive fuzzy evaluation Baicheng City
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尼古丁透皮贴剂用于手术后镇痛:一项剂量-范围的初步研究 被引量:2
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作者 Daewha Hong Jessamyn Conell-Price +3 位作者 Sean Cheng Pamela flood 王聪(译) 陈卫民(校) 《麻醉与镇痛》 2010年第4期21-26,共6页
背景一些动物研究已证实尼古丁在手术后有镇痛作用。然而,尼古丁经鼻喷雾剂在临床试验中得到的结果却好坏参半,这可能与其药代动力学的差异有关,或者受试者中有接触过尼古丁的吸烟者。本初步研究在手术前对非吸烟患者应用尼古丁透皮... 背景一些动物研究已证实尼古丁在手术后有镇痛作用。然而,尼古丁经鼻喷雾剂在临床试验中得到的结果却好坏参半,这可能与其药代动力学的差异有关,或者受试者中有接触过尼古丁的吸烟者。本初步研究在手术前对非吸烟患者应用尼古丁透皮贴剂,旨在观察其镇痛作用。方法40例接受普外科手术的受试者参加此项随机、双盲、安慰剂对照的前瞻性研究,患者手术后需留院一晚并采用患者自控镇痛。手术前即刻分别给予受试者剂量为0、5、10或15mg的尼古丁透皮贴剂。本研究观察的主要指标为手术后第1小时及此后5天的疼痛程度,使用数字评价量表(NRS)进行评分。次要指标为镇痛药的用量、血流动力学数据、恶心及镇静情况。结果应用尼古丁透皮贴剂的治疗组在手术后第1小时及手术后5天中,疼痛评分均低于使用安慰剂的对照组,手术后第1小时:P=0.003,NRS均值下降1.4,95%CI=0.3~2.6;手术后5天:P=0.03,NRS均值下降1.0,95%CI=0.1-1.9。尼古丁剂量超过5mg时镇痛效果没有明显的提升。治疗组中有镇痛药的使用量减少、恶心增加、心动过速减少和收缩期血压轻度下降的趋势,但无统计学意义。结论剂量为5—15mg的尼古丁透皮贴剂可降低普外科手术后的疼痛评分,但是不能减少阿片类镇痛药的需求及其产生的副作用。 展开更多
关键词 手术后镇痛 透皮贴剂 尼古丁 剂量 阿片类镇痛药 安慰剂对照 疼痛评分 镇痛作用
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推客带来的厄运:社交媒体如何影响食品安全与风险交流 被引量:2
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作者 Matt Raymond Anthony flood 《食品安全导刊》 2014年第5期68-69,共2页
一场看来简单的肚子疼,很快就发展成令所有公关头痛的痼疾。直到问题解决.有四个孩子去世.上百个孩子染病。消费者的信任力被严重打击,企业也”名”悬崖边。这就是1992~1993年爆发的大肠杆菌事件,该事件是食品安全问题的领头羊.... 一场看来简单的肚子疼,很快就发展成令所有公关头痛的痼疾。直到问题解决.有四个孩子去世.上百个孩子染病。消费者的信任力被严重打击,企业也”名”悬崖边。这就是1992~1993年爆发的大肠杆菌事件,该事件是食品安全问题的领头羊.映射出管理和危机沟通的必要性。 展开更多
关键词 食品安全问题 风险交流 媒体 社交 大肠杆菌 消费者 孩子 事件
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Simulation Experiments of Land Surface Physical Processes and Ecological Effect over Different Underlying Surface 被引量:1
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作者 LIU Shu-hua~(1,2), JIANG Hao-yu, HU Fei~2 LIU Hui-zhi~2 LIANG Fu-ming~1, WANG Jiang-hua~1(1. Group of Atmosphere Boundary Layer and turbulence, Ministry Laboratory of Storm and Drought flood Damage, Department of Atmospheric Sciences the School of Physics Peking University, Beijing 100871, China 2. State Key Laboratories of Atmosphere Physics and Chemistry, Institute of Atmospheric Physics, Chinese Academy of Science, Beijing 100029, China) 《地球科学进展》 CAS CSCD 2004年第S1期15-20,共6页
Based on the existing Land Surface Physical Process Models(Deardorff, Dickinson, LIU, Noilhan, Seller, ZHAO), a Comprehensive Land Surface Physical Process Model (CLSPPM) is developed by considering the different phys... Based on the existing Land Surface Physical Process Models(Deardorff, Dickinson, LIU, Noilhan, Seller, ZHAO), a Comprehensive Land Surface Physical Process Model (CLSPPM) is developed by considering the different physical processes of the earth's surface-vegetation-atmosphere system more completely. Compared with SiB and BATS, which are famous for their detailed parameterizations of physical variables, this simplified model is more convenient and saves much more computation time. Though simple, the feas... 展开更多
关键词 Comprehensive land surface Physical process model (CLSPPM) Simulation experiment Land surface physical process Ecological effect.
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电子书也在“读”你
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作者 Alison flood 刘奕舒 《新东方英语(中英文版)》 2013年第5期39-43,共5页
乔治·奥成尔在小说《一九八四》中写道:“老大哥”在看着你。现在,“老大哥”不仅准确地知道读者多长时间可以看完奥威尔的小说,知道读者重点标记了小说的哪些部分,还知道读者接下来要看什么书。对于这种发展,奥威尔是会觉得... 乔治·奥成尔在小说《一九八四》中写道:“老大哥”在看着你。现在,“老大哥”不仅准确地知道读者多长时间可以看完奥威尔的小说,知道读者重点标记了小说的哪些部分,还知道读者接下来要看什么书。对于这种发展,奥威尔是会觉得好玩呢,还是不安? 展开更多
关键词 “读” 电子书 《一九八四》 奥威尔 小说 读者
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树立防汛抗旱新理念 努力实现洪水资源化
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作者 Office of Fujian Provincial flood Control and Drought Relief Headquarters 《中国水利》 2005年第7期41-43,共3页
“两个转变”对福建省防汛抗旱实践具有重要的指导作用。在控制洪水向洪水管理转变的探索中,工程体系是基础,管理规范化是关键,洪水资源化是方向,技术现代化是动力。在单一抗旱向全面抗旱转变中,福建省提出了全社会协同抗旱、以人为本... “两个转变”对福建省防汛抗旱实践具有重要的指导作用。在控制洪水向洪水管理转变的探索中,工程体系是基础,管理规范化是关键,洪水资源化是方向,技术现代化是动力。在单一抗旱向全面抗旱转变中,福建省提出了全社会协同抗旱、以人为本抗旱、抗旱效益最大化的抗旱理念。 展开更多
关键词 洪水资源化 防汛抗旱 新理念 管理规范化 技术现代化 效益最大化 指导作用 洪水管理 控制洪水 工程体系 以人为本 福建省
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讲故事——空前有效的交流工具
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作者 Joe flood 常青 《疯狂英语(初中天地)》 2017年第9期20-22,共3页
Human history begins with stories. These stories were so important that they were memorized and passed down for countless generations.Storytelling is an ancient and powerful tool. The ability to 1)process, remember an... Human history begins with stories. These stories were so important that they were memorized and passed down for countless generations.Storytelling is an ancient and powerful tool. The ability to 1)process, remember and communicate stories is man’s oldest and best trick. 展开更多
关键词 交流工具 讲故事 REMEMBER with that for The IS
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缺氧性脑损伤的新疗法?
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作者 Pamela flood, MD 邬娇(译) 郭曲练(校) 《麻醉与镇痛》 2008年第6期88-89,共2页
缺氧性脑损伤是一种可出现在麻醉、手术和分娩过程中的严重并发症。缺氧性损伤通过激活一系列细胞信号传导通路而导致细胞坏死和凋亡。其远期影响可引起短时记忆和工作记忆的破坏性改变。大脑海马区是编码工作记忆的关键部位,这一区域... 缺氧性脑损伤是一种可出现在麻醉、手术和分娩过程中的严重并发症。缺氧性损伤通过激活一系列细胞信号传导通路而导致细胞坏死和凋亡。其远期影响可引起短时记忆和工作记忆的破坏性改变。大脑海马区是编码工作记忆的关键部位,这一区域对缺氧性损伤十分敏感。 展开更多
关键词 缺氧性脑损伤 细胞信号传导通路 缺氧性损伤 疗法 短时记忆 严重并发症 大脑海马区 分娩过程
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麻醉相关效应:丙泊酚麻醉患者的手术后疼痛轻于异氟烷麻醉患者
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作者 Sean S. Cheng, MS Janet Yeh, BS +1 位作者 Pamela flood, MD 浦少峰(译) 《麻醉与镇痛》 2009年第2期56-62,共7页
背景临床前期实验显示某些挥发性麻醉药可能通过抑制烟碱受体引起痛觉过敏。早期的实验证实,给予异氟烷麻醉的女性患者鼻腔内喷雾烟碱,具有手术后镇痛作用。为了确定烟碱是逆转了异氟烷引起的痛觉过敏,还是单纯充当了镇痛药的角色,... 背景临床前期实验显示某些挥发性麻醉药可能通过抑制烟碱受体引起痛觉过敏。早期的实验证实,给予异氟烷麻醉的女性患者鼻腔内喷雾烟碱,具有手术后镇痛作用。为了确定烟碱是逆转了异氟烷引起的痛觉过敏,还是单纯充当了镇痛药的角色,本研究探讨了烟碱对异氟烷+芬太尼或丙泊酚+芬太尼麻醉的女性患者手术后疼痛的影响。方法此项随机、前瞻、双盲研究,对80例采用异氟烷或丙泊酚麻醉行开腹子宫手术的女性患者加以研究。在2个麻醉组中,受试者又被随机分为烟碱3mg组或安慰剂组。数字模拟疼痛评分是首要的观察指标。结果患者的基本情况相似。丙泊酚麻醉组手术后第1天的疼痛评分及吗啡用量要小于异氟烷麻醉组(P〈0.01,P〈0.01)。烟碱的使用没有改变任一组的疼痛评分及吗啡用量(P〉0.05)。结论采用丙泊酚行全身麻醉的患者手术后疼痛及吗啡用量要小于异氟烷麻醉的患者。本研究中烟碱不具有镇痛作用。若上述结果在其他人群中具有可重复性,那么丙泊酚麻醉除具有以前报道的改善恶心、呕吐外的潜在优势外,还能减轻手术后疼痛。 展开更多
关键词 手术后疼痛 氟烷麻醉 丙泊酚 术后镇痛作用 烟碱受体 挥发性麻醉药 女性患者 疼痛评分
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Implementation of Dynamic Line Rating in a Sub-Transmission System for Wind Power Integration
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作者 Saifal Talpur Carl Johan Wallnerstrom +1 位作者 Patrik Hilber Christer flood 《Smart Grid and Renewable Energy》 2015年第8期233-249,共17页
Based on conventional static line rating method, the actual current carrying capability of overhead conductors cannot be judged. Due to continuous increment in electricity demand and the difficulties associated with n... Based on conventional static line rating method, the actual current carrying capability of overhead conductors cannot be judged. Due to continuous increment in electricity demand and the difficulties associated with new line constructions, the overhead lines are therefore required to be rated based on a method that should establish their real-time capability in terms of electricity transmission. The method used to determine the real-time ampacity of overhead conductors not only can enhance their transmission capacity but can also help in allowing excessive renewable generation in the electricity network. In this research work, the issues related to analyzing an impact of wind power on periodical loading of overhead line as well as finding its static and dynamic ampacities with line current are investigated in detail. Moreover, the investigation related to finding a suitable location for the construction of a 60 MW wind farm is taken on board. Thereafter, the wind park is integrated with a regional grid, owned by Fortum Distribution AB. In addition to that, the electricity generated from the wind park is also calculated in this project. Later on, the work is devoted to finding the static and dynamic line ratings for “VL3” overhead conductor by using IEEE-738-2006 standard. Furthermore, the project also deals with finding the line current and making its comparison with maximum capacity of overhead conductor (VL3) for loading it in such a way that no any violation of safe ground clearance requirements is observed at all. Besides, the line current, knowing the conductor temperature when it transmits the required electricity in the presence of wind power generation is also an important factor to be taken into consideration. Therefore, based on real-time ambient conditions with actual line loading and with the help of IEEE-738-2006 standard, the conductor temperature is also calculated in this project. At the end, an economic analysis is performed to evaluate the financial advantages related to applying the dynamic 展开更多
关键词 Overhead Conductor STATIC and DYNAMIC Ampacities Real-Time Weather Conditions STATIC and DYNAMIC LINE RATING Techniques WIND Power Integration Regional Grid LINE Current. Conductor Temperature WIND Power ECONOMICS DYNAMIC LINE RATING ECONOMICS
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Qinghai Mountain Disasters and Countermeasures
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作者 HAN Yongrong (Office of flood Control and Drought Resistance, Qinghai Provincial Government) LI Haiming (Qinghai Institute of Water Conservancy and Hydraulic Power) 《Natural Disaster Reduction in China》 2001年第3期28-36,共9页
The paper presents a detailed account of the status quo and potential hazards of geological environmental disasters (GED) in Qinghai Province as well as a systematic analysis of the formation and evolution of GED ... The paper presents a detailed account of the status quo and potential hazards of geological environmental disasters (GED) in Qinghai Province as well as a systematic analysis of the formation and evolution of GED and of the threat and loss caused to the life and property of the local people. Recommendations on how to take effective measures to prevent and control the GED in Qinghai are provided. 展开更多
关键词 GEOLOGICAL DISASTERS CAUSE analysis COUNTERMEASURES
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Fluor SO_x净化工艺——为俄罗斯绿色环境开发的将SO_2转化为元素硫的经济技术
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作者 T.K.Chow V.W.Wong +3 位作者 T.M.flood J.A.Gebur 纪罗军(译) 瑾(校) 《硫酸工业》 CAS 2006年第2期42-47,共6页
Fluor公司开发的Fluor SO_2净化工艺具有广泛多样的工艺布局,可以通过经济的方式定制脱除烟气中的有害组成。该工艺几乎能去除全部SO_2并减少CO排放。Fluor SO_x净化工艺的主要步骤已在多套工业装置中得到成功的证实。除技术可行、经济... Fluor公司开发的Fluor SO_2净化工艺具有广泛多样的工艺布局,可以通过经济的方式定制脱除烟气中的有害组成。该工艺几乎能去除全部SO_2并减少CO排放。Fluor SO_x净化工艺的主要步骤已在多套工业装置中得到成功的证实。除技术可行、经济合理之外,Fluor SO_x净化工艺不会产生任何有害副产物,也不会遇到与SO_3 有关的腐蚀问题。此外,该工艺生产高纯度可市售的元素硫。论述了Fluor SO_x净化工艺的特征、技术和成本优势、设计和操作的简易性以及实施的便利性。 展开更多
关键词 二氧化硫 硫化氢 元素硫 净化
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2002—2005年间纽约州有关分娩与麻醉相关并发症的流行病学研究
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作者 Khadeen Cheesman BS Joanne E. Brady +4 位作者 SM Pamela flood, MD Guohua Li, MD, DrPH 王美青(译) 祁恩耀(译) 钱燕宁(校) 《麻醉与镇痛》 2012年第3期4-12,共9页
背景分娩与麻醉相关并发症的流行病学数据是衡量、评估产科麻醉管理质量和安全的基础,但目前仍缺乏这方面的数据。我们的目的在于,从纽约州各医院分娩的大样本女性人群中,探索麻醉相关并发症的流行病学模式和风险因素,以填补此研究... 背景分娩与麻醉相关并发症的流行病学数据是衡量、评估产科麻醉管理质量和安全的基础,但目前仍缺乏这方面的数据。我们的目的在于,从纽约州各医院分娩的大样本女性人群中,探索麻醉相关并发症的流行病学模式和风险因素,以填补此研究领域的空白。方法在纽约州各医院住院患者数据库中医疗成本与核算项目的文档中,我们找出了2002—2005年间所有在纽约州各医院分娩患者的出院记录,随后挑选出在分娩期间经历过任-麻醉相关并发症并被记录下来的产妇,这些并发症是根据第9版国际疾病分类,临床修订代码(ICD-9-CM)所确认的。通过人口统计学和患者的临床特点,我们估算出了这些并发症的发生率,并利用多元回归分析法来评估麻醉相关并发症的风险因素。结果在研究了957471例分娩患者中,有4438例(0.46%)患者出现至少一种麻醉相关并发症,在这些并发症中,大多数是脊髓并发症(55%),其他依次是,系统性并发症(43%)和药物过量或不良反应(2%)。多元回归分析揭示了5种麻醉相关并发症的风险因素:剖宫产(OR值为2.51,95%CI值为2.36,2.68),农村地区(OR值为1.33,95%CI值为1.21—1.46),查尔森·德米合并症指数≥1(OR值为1.47,95%CI值为1.28-1.69),白种人(OR值为1.37,95%CI值为1.24—1.52)和预约入院的患者(OR值为1.10,95%CI值为1.03—1.18)。发生麻醉相关并发症的产妇与未发生的相比,其平均住院天数(均数±标准差)延长了一天,分别为(3.89±3.69)天和(2.92±2.38)天,并且使产妇死亡的风险增加了22倍。结论在分娩过程中,麻醉相关并发症的发生率看似很低,但仍然值得我们关注,特别是对那些需要剖宫产、生活在农村地区或者先前存在合并症的产妇。 展开更多
关键词 相关并发症 产科麻醉 分娩期间 流行病学 纽约 多元回归分析法 住院患者 风险因素
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布兰登的礼物
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作者 Myrna flood 李威 《英语自学》 2004年第7期7-9,共3页
我儿子布兰登已经21岁了,他在俄勒冈州林菲尔德大学读四年级,所学专业是基础教育,以后将会成为一名教师。
关键词 布兰 林菲 俄勒冈州 辛德勒 FAVORITE NEVER 数学问题 生下来 自助餐厅 兰登
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吸入麻醉药在大鼠最小肺泡有效浓度上无协同作用
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作者 Edmond I Eger II Michael Tang +11 位作者 Mark Liao Michael J. Laster Ken Solt Pamela flood Andrew lenkins Douglas Raines Jan F. Hendrickx Steven L. Shafer Tanifuji Yasumasa James M. Sonner 杨静(译) 米卫东(校) 《麻醉与镇痛》 2010年第1期1-8,共8页
背景本研究假设对特定受体或通道具有不同作用强度[一种在最小肺泡麻醉药浓度(MAC)时作用弱,另一种则作用较强]的两个吸入麻醉药联合使用时可产生协同作用.这种非单纯相加的相互作用方式将支持麻醉药是通过多位点作用而产生麻醉效应... 背景本研究假设对特定受体或通道具有不同作用强度[一种在最小肺泡麻醉药浓度(MAC)时作用弱,另一种则作用较强]的两个吸入麻醉药联合使用时可产生协同作用.这种非单纯相加的相互作用方式将支持麻醉药是通过多位点作用而产生麻醉效应的论点。方法根据药物作用强度差别(一个作用弱,一个作用强),我们研究了11组相加为1MAC的麻醉药物对某特定受体或通道的作用.此处“作用强度差别”是指两种麻醉药在体外对特定受体或通道的增强或阻断作用,按MAC计算,作用较强者至少是较弱者的两倍(或更多)。这些特定受体包括:TREK-1和TASK-3钾通道;γ-氨基丁酸A(GABAA)、甘氡酸、N-甲基-D-天门冬氡酸和乙酰胆碱受体。我们还研究了环丙烷-苯酚组合,因为N-甲基-D-天门冬氨酸受体阻滞剂MK-801对这两种药物MAC的影响明显不同。此外,纳入研究的还有4对包含氧化亚氯的组合,因为有报道氧化亚氮与异氟烷联合应用可产生亚相加作用(拮抗作用)。结果除氧化亚氮和异氟烷组合产生了拮抗作用之外,其余所有组合的作用强度均在所预计两者之和10%的范围以内.结论本研究结果支持“吸入麻醉药是作用于单一位点而抑制伤害刺激所致体动反应”的观点。 展开更多
关键词 吸入麻醉药 肺泡有效浓度 N-甲基-D-天门冬氨酸受体阻滞剂 协同作用 乙酰胆碱受体 Γ-氨基丁酸 天门冬氡酸 大鼠
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结肠镜筛查女性人群结肠直肠瘤
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作者 Schoenfeld P. Cash B. +1 位作者 flood A. 刘丽娜 《世界核心医学期刊文摘(胃肠病学分册)》 2005年第9期4-5,共2页
BACKGROUND: Veterans Affairs (VA) Cooperative Study 380 showed that some advan ced colorectal neoplasias (i.e., adenomas at least 1 cm in diameter, villous ade nomas, adenomas with highgrade dysplasia, or cancer) in... BACKGROUND: Veterans Affairs (VA) Cooperative Study 380 showed that some advan ced colorectal neoplasias (i.e., adenomas at least 1 cm in diameter, villous ade nomas, adenomas with highgrade dysplasia, or cancer) in men would be missed wi th the use of flexible sigmoidoscopy but detected by colonoscopy. In a tandem st udy, we examined the yield of screening colonoscopy in women. METHODS: To determ ine the prevalence and location of advanced neoplasia, we offered colonoscopy to consecutive asymptomatic women referred for coloncancer screening. The diagno stic yield of flexible sigmoidoscopy was calculated by estimating the proportion of patients with advanced neoplasia whose lesions would have been identified if they had undergone flexible sigmoidoscopy alone. Lesions were considered detect able by flexible sigmoidoscopy if they were in the distal colon or if they were in the proximal colon in patients who had concurrent small adenomas in the dista l colon, a finding that would have led to colonoscopy. The results were compared with the results from VA Cooperative Study 380 for agematched men and women wit h negative fecal occultblood tests and no family history of colon cancer. RESU LTS: Colonoscopy was complete in 1463 women, 230 of whom (15.7 percent) had a fa mily history of colon cancer. Colonoscopy revealed advanced neoplasia in 72 wome n (4.9 percent). If flexible sigmoidoscopy alone had been performed, advanced ne oplasia would have been detected in 1.7 percent of these women (25 of 1463) and missed in 3.2 percent (47 of 1463). Only 35.2 percent ofwomen with advanced neop lasia would have had their lesions identified if they had undergone flexible sig moidoscopy alone, as compared with 66.3 percent of matched men from VA Cooperati ve Study 380 (P< 0.001). CON CLUSIONS: Colonoscopy may be the preferred method of screening for colorectal cancer in women. 展开更多
关键词 结肠直肠 结肠镜筛查 女性人群 乙状结肠镜 早期肿瘤 结肠癌筛查 远端结肠 漏诊率 大便隐血试验 诊断率
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Review of Metal AM Simulation Validation Techniques
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作者 Aaron flood Frank Liou 《Journal of Mechanics Engineering and Automation》 2018年第2期43-52,共10页
Due to the complexity of metal AM (additive manufacturing), it can require many trial runs to obtain processing parameters which produce a quality build. Because of this trial and error process, the drive for simula... Due to the complexity of metal AM (additive manufacturing), it can require many trial runs to obtain processing parameters which produce a quality build. Because of this trial and error process, the drive for simulations of AM has grown significantly. A simulation only becomes useful to researchers if it can be shown that it is a true representation of the physical process being simulated. Each process being simulated has a different method of validation to show it is an accurate representation of the process. This paper explores the various methodologies for validation of laser-based metal AM simulations, focusing mainly on the modeling of the thermal processes and other characteristics derived from the thermal history. It will identify and explain the various validation techniques used, specifically looking at the frequency of reported use of each technique. 展开更多
关键词 AM simulation simulation validation heat transfer modeling stress modeling micro-structure modeling.
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花岗岩类岩石结晶顺序的显微结构证据
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作者 flood,RH 马昌前 《国外花岗岩类地质与矿产》 1989年第2期18-21,共4页
关键词 花岗岩 岩石结晶 显微结构
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临床观测量表评估前的定性和定量研究
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作者 Emuella flood 《药学与临床研究》 2015年第1期57-58,共2页
美国食品药品管理局为使用受试者报告结果(PRO)支持药物审批和产品标签颁布了行业指南,以强调通过定性研究确定临床量表内容有效性的重要性。最近,一些PRO研究人员鼓励使用混合方法确定PRO量表的内容有效性,即推荐在量表开发的认知访谈... 美国食品药品管理局为使用受试者报告结果(PRO)支持药物审批和产品标签颁布了行业指南,以强调通过定性研究确定临床量表内容有效性的重要性。最近,一些PRO研究人员鼓励使用混合方法确定PRO量表的内容有效性,即推荐在量表开发的认知访谈阶段中进行一项Rasch分析。Rasch是一种试题反应理论(IRT)的建模,可在PRO发展过程中用于评估和完善PRO量表。如该建模可确定某些量表项目是否覆盖了设计概念的严重性的全部范围、项目是否冗余,以及反应选项是否有用和作适当排序。这种方法的拥护者认为,认知访谈阶段的Rasch分析将有助于发现内容有效性的问题,以便在开展大规模心理测量有效性研究之前得到解决。 展开更多
关键词 临床结果评价量表(PRO) Rasch分析 混合方法
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