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Eyelid Kaposi Sarcoma in HIV-Negative Patient
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作者 Malalaniaina Andrianarison Malala Razakanaivo +7 位作者 Rindra Rafanomezantsoa Mendrika Fifaliana Rakotoarisaona Odilon Laza fandresena arilala sendrasoa Irina Mamisoa Ranaivo Léa Raobela Lala Soavina Ramarozatovo Fahafahantsoa Rapelanoro Rabenja 《Journal of Cancer Therapy》 2024年第3期92-97,共6页
Introduction: Kaposi sarcoma disease is a proliferative and multifocal disorder with dual components, vascular and fibroblastic cellular, cutaneous and visceral expression. Kaposi Sarcoma can affect the ocular surface... Introduction: Kaposi sarcoma disease is a proliferative and multifocal disorder with dual components, vascular and fibroblastic cellular, cutaneous and visceral expression. Kaposi Sarcoma can affect the ocular surface and adnexa and can masquerade as other entities, delaying prompt diagnosis can lead to diagnostic wandering delaying treatment. Our aim is to describe a case of KS of the eyelid in an HIV seronegative patient. Case Presentation: A seventy-year-old man developed a bilateral growing tumoral reddish purple vascular mass on both the lower and upper eyelid involving rapidly for 6 months. Both feet and the two shanks show the presence of a brown-violet tumor-shaped formation. The patient was negative for HIV. Histology examination showed a nodular tumor-like mass with a fibro hemangioma-epitheliomatous. Polymerase chain reaction was positive for human herpes virus 8. Initial chemotherapy followed by surgery was proposed to the patient. Unfortunately, the patient rejected treatment and was lost to follow-up. Conclusion: This case reports the difficulty of managing KS in developing countries. 展开更多
关键词 EYELID HHV-8 INTERFERON Kaposi Sarcoma
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A Blackish Gingiva Revealing a Metastatic Melanoma of the Oral Mucosa
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作者 Malalaniaina Andrianarison Malala Razakanaivo +4 位作者 Irina Mamisoa Ranaivo fandresena arilala sendrasoa Lala Soavina Ramarozatovo Florine Rafaramino Fahafahantsoa Rapelanoro Rabenja 《Journal of Biosciences and Medicines》 2022年第5期1-6,共6页
Background and Objective: Malignant melanoma is the most aggressive skin cancer because it has very strong metastatic power. Endobuccal localization is very rare. Its discovery is often made in the late stage, which l... Background and Objective: Malignant melanoma is the most aggressive skin cancer because it has very strong metastatic power. Endobuccal localization is very rare. Its discovery is often made in the late stage, which leads to a consistently pessimistic diagnostic. We report a case of palatal melanoma at the metastatic stage. Case Report: A 43-year-old woman presented left lateral cervical swelling associated with dyspnea for 5 months. She had regularly taken chewing tobacco for 4 years and had developed blackish gums. The endobuccal examination showed a blackish non-haemorrhagic swelling of 5 cm of the long axis, located at the level of the palatal vault, associated with pigmentation in teeth 21, 22, and 23. The anatomopathological examination confirmed the melanoma. The spreading assessment revealed pleural and hepatic metastasis. The proposed treatment was palliative treatment. The patient died 2 months later. Conclusion: Melanoma of the oral mucosa is a very aggressive tumor. The scarcities of dental care among the Malagasy people exacerbate the delay in diagnosis. Its management is still challenging in Madagascar. 展开更多
关键词 A Blackish Gingiva Revealing a Metastatic Melanoma of the Oral Mucosa
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