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高铁扣件的自适应视觉检测算法 被引量:9
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作者 范宏 侯云 +1 位作者 李柏林 熊鹰 《西南交通大学学报》 EI CSCD 北大核心 2020年第4期896-902,共7页
为了实现高铁缺陷扣件的准确、快速和自动化检测,提出一种基于图像处理技术的高铁扣件自适应视觉检测算法.针对高铁扣件图像的特性,使用改进的LBP(local binary pattern)算子提取扣件的显著特征;在扣件特征图的基础上,采用模板匹配算法... 为了实现高铁缺陷扣件的准确、快速和自动化检测,提出一种基于图像处理技术的高铁扣件自适应视觉检测算法.针对高铁扣件图像的特性,使用改进的LBP(local binary pattern)算子提取扣件的显著特征;在扣件特征图的基础上,采用模板匹配算法得到扣件区域在原始图中的精确位置,进而得到扣件子图并用扣件的位置信息校验定位结果;以相邻两个扣件子图的差值作为判断依据,如果差值大于预设的阈值,相应的扣件则被判断为缺陷扣件.将该检测算法应用于高铁工务部门提供的真实扣件图.研究结果表明:本文提出的自适应扣件检测算法在雨天的表现最差,检出率为96%,误检率为0.50%;在晴天的表现最好,检出率为100%,误检率为0.22%;在不同天气、光照、环境下的综合检出率为99%,综合误检率为0.33%. 展开更多
关键词 高速铁路 扣件检测 机器视觉 图像处理 模式识别
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ECOLOGICAL SERIES OF SOIL ANIMALS IN DARLIDAI MOUNTAIN 被引量:4
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作者 HOUWei-ling fanhong 《Chinese Geographical Science》 SCIE CSCD 2002年第4期378-382,共5页
The ecological series of soil animals under the broad-leaved and pine mix ed forest in Darlidai Mountain was studied.Seven sample plots were selected according to different altitude gradients,which belong to dif feren... The ecological series of soil animals under the broad-leaved and pine mix ed forest in Darlidai Mountain was studied.Seven sample plots were selected according to different altitude gradients,which belong to dif ferent vegeta-tion types.By investigating and analyzing soil animals in every sample p lot it is found that there are 45group s and 1956individuals,which are involved in 3phylums,7classes,16orders,respectively.The altitude is a key factor which af-fects ecological series of soil anim als.Both the groups and individuals of soil animals increase with altitu de increasing under certain conditions,which con trastes with ordinary cases,resulting from special micro-climate in studied area.The groups and individuls of soil animals are the most under the broad-leaved and pine forest on the top of the mount ain,and the least under Picea-Abies forest in the foot of the mountain. 展开更多
关键词 darlidai mountain soil animals ecological series
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Design and preliminary test of a 105/140 GHz dual-frequency MW-level gyrotron 被引量:3
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作者 Linlin HU Dimin SUN +11 位作者 Qili HUANG Tingting ZHUO Guowu MA Yi JIANG Shenggang GONG Zaojin ZENG Zixing GUO Chaohai DU fanhong LI Hongbin CHEN Fanbao MENG Hongge MA 《Plasma Science and Technology》 SCIE EI CAS CSCD 2022年第3期162-169,共8页
A dual-frequency(105/140 GHz)MW-level continuous-wave gyrotron was developed for fusion application at Institute of Applied Electronics,China Academy of Engineering Physics.This gyrotron employs a cylindrical cavity w... A dual-frequency(105/140 GHz)MW-level continuous-wave gyrotron was developed for fusion application at Institute of Applied Electronics,China Academy of Engineering Physics.This gyrotron employs a cylindrical cavity working in the TE18,7 mode at 105 GHz and the TE24,9 mode at 140 GHz.A triode magnetron injection gun and a built-in quasi-optical mode converter were designed to operate at these two frequencies.For the proof-test phase,the gyrotron was equipped with a single-disk boron nitride window to achieve radio frequency output with a power of~500 k W for a short-pulse duration.In the preliminary short-pulse proof-test in the first quarter of2021,the dual-frequency gyrotron achieved output powers of 300 k W at 105 GHz and 540 k W at140 GHz,respectively,under 5 Hz 1 ms continuous pulse-burst operations.Power upgrade and pulse-width extension were hampered by the limitation of the high-voltage power supply and output window.This gyrotron design was preliminarily validated. 展开更多
关键词 GYROTRON MEGAWATT plasma heating fusion application DUAL-FREQUENCY
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Quality Evaluation Model for Map Labeling 被引量:2
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作者 fanhong ZHANGZuxun DUDaosheng 《Geo-Spatial Information Science》 2005年第1期72-78,共7页
This paper discusses and sums up the basic criterions of guaranteeing the labeling quality and abstracts the four basic factors including the conflict for a label with a label, overlay for label with the features, pos... This paper discusses and sums up the basic criterions of guaranteeing the labeling quality and abstracts the four basic factors including the conflict for a label with a label, overlay for label with the features, position’s priority and the association for a label with its feature. By establishing the scoring system, a formalized four-factors quality evaluation model is constructed. Last, this paper introduces the experimental result of the quality evaluation model applied to the automatic map labeling system-MapLabel. 展开更多
关键词 map labeling quality evaluation model
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MoSx microgrid electrodes with geometric jumping effect for enhancing hydrogen evolution efficiency 被引量:1
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作者 Zhicheng Shang Ying Zhang +8 位作者 Liang Luo Congtian Cheng Tianhui Xie fanhong Chen Siyu Sheng Yun Kuang Wen Liu Haijun Xu Xiaoming Sun 《Science China Materials》 SCIE EI CAS CSCD 2021年第4期892-898,共7页
Bubble evolution behaviors play important roles in bubble emission reactions.Here we fabricated one-dimensional(1D)-aligned MoSx microgrids to investigate the influence of the periodic structure on bubble releasing.It... Bubble evolution behaviors play important roles in bubble emission reactions.Here we fabricated one-dimensional(1D)-aligned MoSx microgrids to investigate the influence of the periodic structure on bubble releasing.It is demonstrated that the utilization of the surface energy released during coalescence of bubbles causes them to jump from the electrode,which can be an effective route to eliminate the bubble shielding effect.Under the optimized architecture with 40-μm-wide grooves,the generated bubbles tend to coalesce and release from the electrode with much smaller size(65%less in volume).By balancing the coalescence efficiency and the adhesive work via the architecture engineering,the electrocatalytic performance can be promoted with the rapid bubble removal and lowered ohmic resistance.The results provide new insights into the rational design of novel catalytic electrode architectures and promote their applications in related fields. 展开更多
关键词 bubble evolution COALESCENCE surface energy
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Study on the Spreading of Environmental Impact of Human Being' s Activities and Its Crucial Factors in Upper Minjiang River 被引量:1
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作者 fanhong ZhaoHong-da 《Wuhan University Journal of Natural Sciences》 CAS 2003年第03B期949-956,共8页
This paper focuses on the historical transition of human being's activities and the eco-environment in the upper reaches of Minjiang River. The history is divided into 4 periods, each with its own feature. During ... This paper focuses on the historical transition of human being's activities and the eco-environment in the upper reaches of Minjiang River. The history is divided into 4 periods, each with its own feature. During the period of nomad immigration, the top-line of the subalpine forest was forced downward by the expanding subalpine meadow. During the period of farming nationality immigration, the bottom-line of middle mountain forest had moved upward forced by the needs for land or timber of the increasing population in the valley basia During the period of the early exploiting, the focus resource was the timber. The total output was limited, comparing with the later period, because of the bad accessibility. But it was large enough to impact the forest ecosystem of the deforesting area. The recent 50 years is the crucial period of economic development and eco-environment degradation. This paper points out that the impact of human being's activities for environment lies on 3 factors: 1) physical features control the location and tendency eco-environmental change; 2) population and productivity control the scale and speed of eco-environmental change; 3) regional accessibility controls the time and location of eco-environmental change. 展开更多
关键词 historical period human being's activities environmental impact crucial factors
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Energy-based robust controller design for flexible spacecraft 被引量:1
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作者 ShuzhiSamGE TongHengLEE +1 位作者 fanhong CherHiangGOH 《控制理论与应用(英文版)》 EI 2004年第1期27-34,共8页
This paper presents a class of non-model-based position controllers for a kind of flexible spacecraft. With the controllers, one can achieve not only the closed-loop stability of the original distributed parameter sys... This paper presents a class of non-model-based position controllers for a kind of flexible spacecraft. With the controllers, one can achieve not only the closed-loop stability of the original distributed parameter system, but also the asymptotic stability of the truncated system, which is obtained through representing the deflection of the appendage by an arbitrary finite number of flexible modes. The system dynamics are not explicitly involved in the controller design and stability proof. Instead, only a very basic system energy relationship of the flexible spacecraft is utilized. The controllers possess several remarkable advantages over the traditional model-based ones. Numerical simulations are carried out on a kind of spacecraft with one flexible appendage and satisfactory results are obtained. 展开更多
关键词 Energy-based control Flexible spacecraft Distributed parameter systems
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Bubble Consumption Dynamics in Electrochemical Oxygen Reduction
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作者 CHEN fanhong ZHOU Daojin +8 位作者 LU Zhiyi WANG Cheng LUO Liang LIU Yiwei SHANG Zhicheng SHENG Siyu CHENG Congtian XU Haijun SUN Xiaoming 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2020年第3期473-478,共6页
Electrochemical oxygen reduction reaction(ORR)is crucial for fuel cells and metal-air batteries,while the oxygen consumption dynamics study during ORR,which affects the ORR efficiency,is not as concerned as catalysts ... Electrochemical oxygen reduction reaction(ORR)is crucial for fuel cells and metal-air batteries,while the oxygen consumption dynamics study during ORR,which affects the ORR efficiency,is not as concerned as catalysts design does.Herein the consumption behavior of an individual oxygen bubble on Pt foils with different wettabilities during ORR was tracked by a real-time approach to reveal whether the surface wettability of electrode can influence the consumption dynamics and determine the reaction reactive zones of oxygen bubble consumption.The oxygen bubble underwent a "constant contact angle"dominant consumption model on aerophobic Pt foil,while an initial "constant radius"and the subsequent"constant contact angle"oxygen consumption models were observed on aero philic Pt foil.Results here demonstrated that the current was proportional to the bottom contact area,rather than the three-phase contact line of the bubbles according to the fitting curves between individual bubble current and the consumption behavior parameters.This study highlights the important role of the gas-solid interface in influencing the efficiency of gas consumption electrochemical reactions,which shall benefit the understanding of reaction kinetics and the rational design of electrocatalysts. 展开更多
关键词 Gas consumption Electrochemical reaction Interface study Aerophobic Aerophilic
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Synthesis and Biological Evaluation of Gem-Difluoro- methylenated Statin Derivatives as Highly Potent HMG-CoA Reductase Inhibitors
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作者 Zhao Zhao Jiaxin Cui +7 位作者 Yan Yin Heng Zhang Yecheng Liu Rui Zeng Chao Fang Zhenpeng Kai ZhonghuaWang fanhong Wu 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2016年第8期801-808,共8页
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Reviews on SCI Journals of Traditional Medicine from 2013-2017
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作者 Zhou Ajian Liu Zining +1 位作者 Meng fanhong Zou Jianhua 《World Journal of Integrated Traditional and Western Medicine》 2018年第2期29-37,共9页
OBJECTIVE: To give a general introduction of journals on traditional medicine, which have been collected by the Science Citation Index(SCI). METHODS: A keyword search was conducted on the SCIE journals on the Thomson ... OBJECTIVE: To give a general introduction of journals on traditional medicine, which have been collected by the Science Citation Index(SCI). METHODS: A keyword search was conducted on the SCIE journals on the Thomson Reuters website(http://www.thomsonscientific.com.cn) with the search formula "Alternative OR Complementary OR Integrative OR Chinese Medicine OR Medicinal OR Ethnopharmacology OR Manipulative OR Natural Medicine OR Natural Product OR Phytotherapy OR Phytomedicine OR Homeopathy OR Acupuncture OR Planta OR Traditional OR Ayurvedic OR Herb OR Herbal". RESULTS: A total of 32 kinds of traditional medicine journals were collected by SCI, of which 30 are in English and the rest are in German.The subject of traditional medical journals covered by SCI covers traditional medicine, supplementary and alternative therapies, botanicals, and natural medicines. Chinese medicine professionals in China can take these factors into consideration when using literature or choosing the direction of paper submission. CONCLUSION: The IF of traditional medicine related journals are relative low, while those of biology and natural drugs are relative high. IF should not be considered as the only factor to evaluate the impact and academic level of journals. 展开更多
关键词 Science CITATION index TRADITIONAL MEDICINE REVIEWS
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Enatioselective Chalcogeno-Baylis-Hillman Reaction of Arylaldehydes with MVK and Acrylates Catalyzed by Chiral Thiepin-TiCl_(4) Complex
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作者 Yan Yin Guofeng Sun +2 位作者 Heng Zhang Hong Zhou fanhong Wu 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2014年第4期365-369,共5页
In a rational chiral molecular design of chalcogenides,optically active thiepin with C_(2)-symmetric chirality was synthesized from commercially available thiophene.Then enatioselective Chalcogeno-Baylis-Hillman react... In a rational chiral molecular design of chalcogenides,optically active thiepin with C_(2)-symmetric chirality was synthesized from commercially available thiophene.Then enatioselective Chalcogeno-Baylis-Hillman reactions of arylaldehydes with methyl vinyl ketone(MVK)and acrylates were investigated in the presence of thiepin-Lewis acid complex.Finally,up to 64%ee was achieved in the presence of 0.2 equiv.of(S)-thiepin at 20℃. 展开更多
关键词 3 3'-bithienyls chiral thiepin Chalcogeno-Baylis-Hillman reaction CHALCOGENIDES TiCl_(4)
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Agent's Optimal Compensation Under Inflation Risk by Using Dynamic Contract Model
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作者 FEI Chen FEI Weiyin +1 位作者 ZHANG fanhong YANG Xiaoguang 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2021年第6期2291-2309,共19页
This paper studies the problem of principal-agent with moral hazard in continuous time.The firm’s cash flow is described by geometric Brownian motion(hereafter GBM).The agent affects the drift of the firm’s cash flo... This paper studies the problem of principal-agent with moral hazard in continuous time.The firm’s cash flow is described by geometric Brownian motion(hereafter GBM).The agent affects the drift of the firm’s cash flow by her hidden effort.Meanwhile,the firm rewards the agent with corresponding compensation and equity which depend on the output.The model extends dynamic optimal contract theory to an inflation environment.Firstly,the authors obtain the dynamic equation of the firm’s real cash flow under inflation by using the It?formula.Then,the authors use the martingale representation theorem to obtain agent’s continuation value process.Moreover,the authors derive the Hamilton-Jacobi-Bellman(HJB)equation of investor’s value process,from which the authors derive the investors’scaled value function by solving the second-order ordinary differential equation.Comparing with He;,the authors find that inflation risk affects the agent’s optimal compensation depending on the firm’s position in the market. 展开更多
关键词 Equity incentive inflation risk It?formula principal-agent problem the martingale representation theorem
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A Hopfield Neural Network Algorithm for Automatic Name Placement for Point Feature
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作者 fanhong TANGGuoqiang +1 位作者 ZHANGZuxun DUDaosheng 《Geo-Spatial Information Science》 2004年第2期144-147,共4页
This paper presents a method of adding label to the map especially for the point feature. This method overcomes the shortcoming of traditional methods, e.g. Conflict\|Backtracking method. Its kernel algorithm use the ... This paper presents a method of adding label to the map especially for the point feature. This method overcomes the shortcoming of traditional methods, e.g. Conflict\|Backtracking method. Its kernel algorithm use the hopfield neural network to find the best label position for point feature. The experimental results proves that this algorithm has good permanence and high speed. 展开更多
关键词 hopfield neural network energy function map name placement
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电力系统惯性的时空特性及分析方法 被引量:63
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作者 曾繁宏 张俊勃 《中国电机工程学报》 EI CSCD 北大核心 2020年第1期50-58,共9页
随着风电及光伏渗透率的提高,电力系统的惯性在特点及形式上发生新的变化。传统的电力系统惯性研究主要集中在系统或区域层面,没有针对电力系统各节点进行惯性研究,无法把握电力系统惯性的时空特性,难以为系统安全稳定运行提供更多有价... 随着风电及光伏渗透率的提高,电力系统的惯性在特点及形式上发生新的变化。传统的电力系统惯性研究主要集中在系统或区域层面,没有针对电力系统各节点进行惯性研究,无法把握电力系统惯性的时空特性,难以为系统安全稳定运行提供更多有价值的细节信息。针对这一问题,该文从惯性的物理属性出发,首先,对电力系统的惯性特征进行阐述;然后,定义电力系统的节点惯性,并给出其物理解释和表征方法;其次,基于节点频率在大扰动下和小扰动下的动态特性,分析电力系统惯性的时空特性,并从小扰动下节点频率频谱中提取指标对惯性时空特性进行可视化,实现对电力系统惯性的实时监控。最后,以10机39点系统为例进行仿真分析,验证所提方法的有效性。 展开更多
关键词 电力系统惯性 惯量支撑 节点频率 节点惯性 时空特性
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日光温室不同时段补光对番茄果实品质及挥发性物质影响 被引量:29
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作者 魏守辉 肖雪梅 +7 位作者 钟源 郁继华 吕剑 胡琳莉 唐中祺 柳帆红 王舒亚 坚乃丹 《农业工程学报》 EI CAS CSCD 北大核心 2020年第8期188-196,共9页
为探明日光温室中提高番茄产量和品质的最佳补光时段,以"粉太郎"番茄为试材,从植株定植后第25天到第一穗果完全成熟时进行补光,利用LED灯设置3种补光时段:揭帘前补光5 h(T1)、盖帘后补光5 h(T2)、揭帘前盖帘后分别补光2.5h(T... 为探明日光温室中提高番茄产量和品质的最佳补光时段,以"粉太郎"番茄为试材,从植株定植后第25天到第一穗果完全成熟时进行补光,利用LED灯设置3种补光时段:揭帘前补光5 h(T1)、盖帘后补光5 h(T2)、揭帘前盖帘后分别补光2.5h(T3),以不补光作为对照(CK),研究其对番茄产量、果实品质以及挥发性物质成分和含量的影响。结果表明:补光处理可提高番茄平均单株产量、果实可溶性糖含量、可溶性固形物含量、糖酸比、挥发性物质总数量和总质量分数,但会降低有机酸含量,T1处理效果最显著(P<0.05)。4个处理共检测出83种挥发性物质,包括12种酮类、22种醛类、22种醇类、6种酯类、6种烃类和15种其他类物质。各处理挥发性物质总数量和总质量分数由大到小为:T1(68种,3 107.98μg/kg)、T3(65种,2 610.74μg/kg)、T2(63种,2 438.96μg/kg)、CK(59种,2 086.03μg/kg)。每个处理醇类含量最多,烃类含量最低,并且含量最高的物质均是顺-3-己烯-1-醇。3种补光处理均可提高酮类、醛类、醇类和其他类物质含量,但显著降低烃类物质含量(P<0.05),酯类物质含量只在T1处理时有所提高。所有被检测出的挥发性物质包含11种番茄特征香气成分,主要分为花香、果香与青香3种类型,其中青香味物质含量最多。综上,对番茄进行补光尤其是揭帘前补光5 h可有效提高番茄产量、果实品质和风味,是当地日光温室越冬茬番茄栽培的较优补光时段。研究结果可为设施番茄种植的光环境调控技术提供科学依据。 展开更多
关键词 温室 光质 番茄 补光时段 产量 果实品质 挥发性物质 顶空固相微萃取 气相色谱-质谱联用
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不同时段补光对日光温室番茄营养与风味品质的影响 被引量:19
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作者 柳帆红 肖雪梅 +6 位作者 郁继华 吕剑 胡琳莉 魏守辉 唐中祺 罗石磊 钟源 《西北农业学报》 CAS CSCD 北大核心 2020年第4期570-578,共9页
在日光温室基质栽培条件下,以‘粉太郎’番茄(Solanum lycopersicum)为试验材料,采用红蓝光配比为7∶2的LED灯作为光源,设置3个不同补光时段,分别为揭帘前补光5 h(T1)、盖帘后补光5 h(T2)、揭帘前和盖帘后各补光2.5 h(T3),以不补光为对... 在日光温室基质栽培条件下,以‘粉太郎’番茄(Solanum lycopersicum)为试验材料,采用红蓝光配比为7∶2的LED灯作为光源,设置3个不同补光时段,分别为揭帘前补光5 h(T1)、盖帘后补光5 h(T2)、揭帘前和盖帘后各补光2.5 h(T3),以不补光为对照(CK),研究了不同时段补光对番茄成熟果实总产量、糖酸组分及番茄红素质量分数的影响。结果表明,补光能够显著增加番茄果实总产量,与对照相比,揭帘前补光5 h、盖帘后补光5 h、揭帘前和盖帘后各补光2.5 h分别增加4.23%、12.91%、16.63%;揭帘前补光5 h显著增加番茄果实中果糖、葡萄糖、蔗糖和总糖及番茄红素质量分数,分别为40.48%、53.33%、66.66%、47.25%和31.52%,而柠檬酸、苹果酸、有机酸质量分数差异不显著,从而显著增加番茄果实中糖酸比;盖帘后补光5 h和揭帘前和盖帘后各补光2.5 h分别显著降低番茄果实中蔗糖和果糖质量分数,而总糖、苹果酸、酒石酸、糖酸比及番茄红素质量分数差异不显著。不同时段补光处理的番茄果实糖酸各组分及番茄红素之间存在一定相关性,其中果糖、葡萄糖和总糖质量分数两两之间呈极显著正相关,柠檬酸和有机酸质量分数呈显著正相关,酒石酸与果糖、葡萄糖和总糖质量分数呈极显著正相关,与蔗糖质量分数呈显著正相关;番茄红素质量分数与总糖、各糖组分、苹果酸质量分数呈显著正相关。因此,揭帘前补光5 h可显著增加番茄果实的总产量,同时有利于促进番茄果实各糖酸组分质量分数的积累,从而提高番茄果实中总糖、有机酸质量分数和糖酸比,且增加番茄果实中番茄红素的质量分数,进而提高番茄营养与风味品质。 展开更多
关键词 番茄 补光时段 品质 相关性
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开放型TDLAS-WMS技术CO_(2)痕量气体检测 被引量:18
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作者 赵成龙 黄丹飞 +4 位作者 刘智颖 王昱琪 钟艾琦 张耹铭 孟凡宏 《光子学报》 EI CAS CSCD 北大核心 2022年第2期323-332,共10页
采用窄线宽、边模抑制高的DFB激光器研制一套开放型TDLAS波长调制技术气体检测装置。选取2004 nm处CO_(2)分子吸收峰作为吸收谱线,采用锁相放大器进行调制、解调后的二次谐波信号幅值检测气体浓度大小。设计基于开放环境中的Herriott型... 采用窄线宽、边模抑制高的DFB激光器研制一套开放型TDLAS波长调制技术气体检测装置。选取2004 nm处CO_(2)分子吸收峰作为吸收谱线,采用锁相放大器进行调制、解调后的二次谐波信号幅值检测气体浓度大小。设计基于开放环境中的Herriott型气体吸收池,使用ZEMAX非序列模式进行吸收池仿真,光线追迹后理论光程可达到1350 mm,实际光程由50 mm增加到300 mm,检测浓度下限数值由原先的1300 ppmv降低到214.28 ppmv,有效提高了系统的检测下限能力。配置不同浓度的CO_(2)气体检测,得到二次谐波信号幅值与浓度之间呈现很好的线性关系,其拟合系数为0.99839,可通过拟合直线方程计算得出待测气体的浓度。配置300 ppmv的CO_(2)进行Allan方差分析,积分时间到101.6 s时,Allan方差处于平稳状态,检测系统的灵敏度为1.512×10^(-5)。检测结果表明检测装置实现了对CO_(2)气体浓度准确测量。该装置可进行结核分枝杆菌呼吸产生的CO_(2)气体浓度进行检测,为肺结核病诊断提供依据。 展开更多
关键词 TDLAS-WMS 谐波信号 痕量气体检测 DFB激光器 CO_(2)
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血栓通对非动脉炎性前部缺血性视神经病变患者视力、视野改善效果及作用机制分析 被引量:16
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作者 关怀英 孔凡宏 +1 位作者 张大卫 吴胜卫 《中国煤炭工业医学杂志》 2018年第1期6-10,共5页
目的分析血栓通对非动脉炎性前部缺血性视神经病变(AION)患者视力、视野改善效果及其作用机制。方法选取我院2014年9月—2017年3月收治的78例(81眼)非动脉炎性AION患者,以随机数表法分为观察组(39例,40眼)和对照组(39例,41眼)。二组均... 目的分析血栓通对非动脉炎性前部缺血性视神经病变(AION)患者视力、视野改善效果及其作用机制。方法选取我院2014年9月—2017年3月收治的78例(81眼)非动脉炎性AION患者,以随机数表法分为观察组(39例,40眼)和对照组(39例,41眼)。二组均给予激素治疗,对照组肌肉注射注射用鼠神经生长因子、穴位注射复方樟柳碱注射液以及口服甲钴胺片,观察组在对照组治疗基础上静脉滴注血栓通注射液,均连续治疗4周。评定临床疗效,并评估视力、视野改善效果。结果观察组临床治疗总有效率为92.31%,明显高于对照组(74.36%)(P<0.05)。与对照组比较,观察组视盘水肿改善程度明显高,且视盘水肿完全吸收时间明显缩短(P<0.05)。二组治疗前视力均以<0.5为主,且视力状况比较差异无统计学意义(P>0.05),治疗后二组视力均显著改善,观察组视力以≥0.8为主,对照组以≥0.5为主,观察组视力改善效果显著优于对照组(P<0.05)。二组治疗前平均光敏度、平均视野缺损比较差异无统计学意义(P>0.05),治疗后平均光敏度、平均视野缺损均显著改善,与治疗前比较差异有统计学意义(P<0.05),且与对照组比较,治疗后观察组视野平均光敏度显著提高,平均视野缺损显著减小(P<0.05)。结论血栓通辅助治疗非动脉炎性AION可有效改善患者视觉通路、视盘水肿,改善视野和提高视力,从而有效防治视神经萎缩,改善生活质量。 展开更多
关键词 血栓通 非动脉炎性前部缺血性视神经病变 视野 视力
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15种高危型人乳头瘤病毒核酸检测方法验证及人群感染情况调查 被引量:11
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作者 王萌萌 孔凡虹 +5 位作者 宗曾艳 张水兰 阚丽娟 汤花梅 张秀明 熊丹 《国际检验医学杂志》 CAS 2020年第1期1-5,9,共6页
目的 对实时荧光定量PCR(qPCR)方法检测高危型人乳头瘤病毒(HPV)核酸进行方法学评价,同时对本院妇产科15种高危型HPV感染情况进行调查。方法 参考相关文件对性能评价的要求,验证检测方法的重复性、准确度、测定下限和抗干扰能力。对2018... 目的 对实时荧光定量PCR(qPCR)方法检测高危型人乳头瘤病毒(HPV)核酸进行方法学评价,同时对本院妇产科15种高危型HPV感染情况进行调查。方法 参考相关文件对性能评价的要求,验证检测方法的重复性、准确度、测定下限和抗干扰能力。对2018年6月至2019年4月份深圳市罗湖区医学检验中心妇产科23 276例HPV送检标本检测结果进行分析。结果 HPV高危分型试剂盒批内及批间阴阳性符合率均≥95.00%,室间质评结果符合率为100.00%,临界阳性标本重复性检测的阳性检出率为100.00%。HPV不同型别之间及与多种生殖道常见微生物之间无交叉反应,红细胞浓度达4.00%对检测结果无内源性干扰。HPV总体感染率为19.77%。高危型HPV感染年龄呈“U”形分布,≤25岁年龄段感染率最高(28.70%),其次为≥56岁年龄段(27.63%)。总体感染率排名前5位的HPV基因型别依次为56、58、16、51、68型。各年龄组以单一感染最多见。结论 qPCR方法是一种快速、便捷、准确、稳定检测HPV的方法,适用于大规模的临床HPV样本检测。深圳市罗湖区HPV感染亚型分布存在地区特异性,5个年龄组不同HPV感染状况亦有差异。流行病学调查结果为HPV感染的临床诊断和防治提供参考依据。 展开更多
关键词 人乳头瘤病毒 基因分型 性能验证 流行病学调查
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肝爽颗粒在慢性乙型肝炎肝硬化中的应用观察 被引量:10
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作者 陈芳芳 张文杰 +7 位作者 李静 田淑菊 屈延 王鹏 韩飞 李翻红 马蓉霞 杨晓娟 《中华中医药学刊》 CAS 北大核心 2022年第2期231-233,共3页
目的探讨肝爽颗粒治疗乙肝肝硬化的疗效及对Th17/Treg的影响。方法122例慢性乙型肝炎肝硬化患者随机分为对照组和观察组各61例,对照组予恩替卡韦治疗,观察组加用肝爽颗粒,24周为1个疗程。比较肝功能指标(ALT、AST、Alb、TBil),肝纤维化... 目的探讨肝爽颗粒治疗乙肝肝硬化的疗效及对Th17/Treg的影响。方法122例慢性乙型肝炎肝硬化患者随机分为对照组和观察组各61例,对照组予恩替卡韦治疗,观察组加用肝爽颗粒,24周为1个疗程。比较肝功能指标(ALT、AST、Alb、TBil),肝纤维化指标(HA、CⅣ、PCⅢ、LN),Th17/Treg及相关细胞因子含量。两组间计量资料比较采用独立样本t检验,治疗前后比较采用配对t检验。结果治疗后,观察组ALT、TBil、HA、PCⅢ、LN、Th17、Treg、Th17/Treg、IL-17、IL-23、IL-10、IL-35均明显低于对照组;Alb明显高于对照组(P<0.05)。两组CⅣ无显著差异(P>0.05)。结论肝爽颗粒可提高慢性乙型肝炎肝硬化患者肝功能,减轻肝纤维化程度,其机制可能与调节Th17/Treg有关。 展开更多
关键词 肝爽颗粒 慢性乙型肝炎 肝硬化 疗效 TH17/TREG
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