Calcium-magnesium-alumino-silicate(CMAS)corrosion is a critical factor which causes the failure of thermal barrier coating(TBC).CMAS attack significantly alters the temperature and stress fields in TBC,resulting in th...Calcium-magnesium-alumino-silicate(CMAS)corrosion is a critical factor which causes the failure of thermal barrier coating(TBC).CMAS attack significantly alters the temperature and stress fields in TBC,resulting in their delamination or spallation.In this work,the evolution process of TBC prepared by suspension plasma spraying(SPS)under CMAS attack is investigated.The CMAS corrosion leads to the formation of the reaction layer and subsequent bending of TBC.Based on the observations,a corrosion model is proposed to describe the generation and evolution of the reaction layer and bending of TBC.Then,numerical simulations are performed to investigate the corrosion process of free-standing TBC and the complete TBC system under CMAS attack.The corrosion model constructs a bridge for connecting two numerical models.The results show that the CMAS corrosion has a significant influence on the stress field,such as the peak stress,whereas it has little influence on the steady-state temperature field.The peak of stress increases with holding time,which increases the risk of the rupture of TBC.The Mises stress increases nonlinearly along the thick direction of the reaction layer.Furthermore,in the traditional failure zone,such as the interface of the top coat and bond coat,the stress obviously changes during CMAS corrosion.展开更多
Trajectory tracking control of space robots in task space is of great importance to space missions, which require on-orbit manipulations. This paper focuses on position and attitude tracking control of a tree-floating...Trajectory tracking control of space robots in task space is of great importance to space missions, which require on-orbit manipulations. This paper focuses on position and attitude tracking control of a tree-floating space robot in task space. Since nei- ther the nonlinear terms and parametric uncertainties of the dynamic model, nor the external disturbances are known, an adap- tive radial basis function network based nonsingular terminal sliding mode （RBF-NTSM） control method is presented. The proposed algorithm combines the nonlinear sliding manifold with the radial basis function to improve control performance. Moreover, in order to account for actuator physical constraints, a constrained adaptive RBF-NTSM, which employs a RBF network to compensate for the limited input is developed. The adaptive updating laws acquired by Lyapunov approach guar- antee the global stability of the control system and suppress chattering problems. Two examples are provided using a six-link free-floating space robot. Simulation results clearly demonstrate that the proposed constrained adaptive RBF-NTSM control method performs high precision task based on incomplete dynamic model of the space robots. In addition, the control errors converge faster and the chattering is eliminated comparing to traditional sliding mode control.展开更多
A major challenge facing photodynamic therapy(PDT) is that the activity of the immuneinduced infiltrating CD8^(+)T cells is subject to the regulatory T lymphocytes(Tregs), leaving the tumor at risk of recurrence and m...A major challenge facing photodynamic therapy(PDT) is that the activity of the immuneinduced infiltrating CD8^(+)T cells is subject to the regulatory T lymphocytes(Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprogram the immunosuppressive tumor microenvironment(TME), a supramolecular photodynamic nanoparticle(DACss) is constructed by the host-guest interaction between demethylcantharidin-conjugated β-cyclodextrin(DMC-CD) and amantadine-terminated disulfide-conjugated FFVLGGGC peptide with chlorin e6 decoration(Ad-ss-pep-Ce6) to achieve intelligent delivery of photosensitizer and immunomodulator for breast cancer treatment. The acid-labile β-carboxamide bond of DMC-CD is hydrolyzed in response to the acidic TME, resulting in the localized release of DMC and subsequent inhibition of Tregs.The guest molecule Ad-ss-pep-Ce6 can be cleaved by a high level of intracellular GSH, reducing photosensitizer toxicity and increasing photosensitizer retention in the tumor. With a significant increase in the CTL/Treg ratio, the combination of Ce6-based PDT and DMC-mediated immunomodulation adequately achieved spatiotemporal regulation and remodeling of the TME, as well as improved primary tumor and in situ lung metastasis suppression with the aid of PD-1 antibody.展开更多
The development of high-performance atomiccatalysts for the carbon dioxide reduction reaction(CO_(2)RR)is atime-consuming process due to the complexity of the reactionmechanism and the uncertainty of the active site.H...The development of high-performance atomiccatalysts for the carbon dioxide reduction reaction(CO_(2)RR)is atime-consuming process due to the complexity of the reactionmechanism and the uncertainty of the active site.Herein,wehave proposed combining density functional theory(DFT)andmachine learning(ML)to investigate the potential of topologicalgraphene-based dual-atom catalysts(DACs)as CO_(2)RRelectrocatalysts.By analyzing the ML results,we identify thenumber of d-orbital electrons in the active site as a key factorinfluencing the CO_(2)RR catalytic activity.Additionally,wepropose a simple descriptor to measure the CO_(2)RR activity ofthese DACs.Our findings provide plausible explanations for thesynergistic interactions between bimetallic atoms in CO_(2)RR andallow us to screen the homogeneous Ni-Ni pair as the mostpromising dual-atom catalysts.This work offers a fast MLapproach based on limited DFT calculations to predict the mostelectroactive and stable DACs on carbon support for CO_(2)RR,facilitating rapid screening of high-performance dual-atomcatalysts.展开更多
Designing high-performance electrocatalysts toward hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)is essential to reduce the activation barrier and optimize free adsorption energy of reactive interm...Designing high-performance electrocatalysts toward hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)is essential to reduce the activation barrier and optimize free adsorption energy of reactive intermediates.Herein,we report that incorporating high-valence Cr into NiSe_(2)(Cr_(x)Ni_(1-x)Se_(2))kinetically and thermodynamically expedites elementary steps of both HER and OER.The as-prepared Cr_(0.05)Ni_(0.95)Se_(2) catalyst displays excellent HER and OER activities,with low overpotentials of 89 and 272 mV at the current density of 10 mA·cm^(-2)(j10),respectively,and remains stable during operation for 30 h.A low cell voltage of only 1.59 V is required to drive j10 in alkaline media.In situ Raman spectroscopy reveals that Cr incorporation facilitates the formation of NiOOH active species during the OER process.Meanwhile,theoretical explorations demonstrate that high-valence Cr incorporation efficiently accelerates water dissociation kinetics and improves H*adsorption during HER process,lowering the activation barrier of OER and optimizing the adsorption energy of oxygen-based intermediate,thus kinetically and thermodynamically enhancing the intrinsic performance of NiSe_(2) for over water splitting.This strategy provides a new horizon to design transition metal based electrocatalysts in the clean energy field.展开更多
In this study,we introduce our newly developed measurement-fed-perception self-adaption Low-cost UAV Coordinated Carbon Observation Network(LUCCN)prototype.The LUCCN primarily consists of two categories of instruments...In this study,we introduce our newly developed measurement-fed-perception self-adaption Low-cost UAV Coordinated Carbon Observation Network(LUCCN)prototype.The LUCCN primarily consists of two categories of instruments,including ground-based and UAV-based in-situ measurement.We use the GMP343,a low-cost non-dispersive infrared sensor,in both ground-based and UAV-based instruments.The first integrated measurement campaign took place in Shenzhen,China,4 May 2023.During the campaign,we found that LUCCN’s UAV component presented significant data-collecting advantages over its ground-based counterpart owing to the relatively high altitudes of the point emission sources,which was especially obvious at a gas power plant in Shenzhen.The emission flux was calculated by a crosssectional flux(CSF)method,the results of which differed from the Open-Data Inventory for Anthropogenic Carbon dioxide(ODIAC).The CSF result was slightly larger than others because of the low sampling rate of the whole emission cross section.The LUCCN system will be applied in future carbon monitoring campaigns to increase the spatiotemporal coverage of carbon emission information,especially in scenarios involving the detection of smaller-scale,rapidly varying sources and sinks.展开更多
文摘以全球变暖为主要特征的气候变化已成为全球性环境问题,对全球可持续发展带来严峻挑战。2015年《巴黎协定》确定了自2020年后国家自主贡献的减排方式,并从2023年开始每5 a开展一次全球碳盘点。2019年第49届IPCC全会明确增加了基于卫星遥感的排放清单校验方法。欧盟、美国、日本、加拿大等正在大力发展温室气体排放的MVS(Monitoring and Verification Support)能力。本文调研分析了全球碳盘点对卫星遥感技术的需求,介绍了全球碳盘点卫星遥感的技术原理,梳理了温室气体卫星遥感、生态系统碳源汇卫星遥感估算、人为源碳排放卫星遥感、碳通量同化估算等全球碳盘点卫星遥感核心环节的研究现状与进展,分析了当前卫星遥感技术对全球碳盘点任务的支撑能力,并结合国内外发展趋势,针对性地提出中国的碳监测卫星计划方案,并展望了中国开展全球碳盘点卫星遥感监测重点任务,期望为中国全球碳盘点卫星遥感体系建设提供思路与方案。
基金This study is supported by the National Natural Science Foundation of China(Nos.1171101165 and 11902240).
文摘Calcium-magnesium-alumino-silicate(CMAS)corrosion is a critical factor which causes the failure of thermal barrier coating(TBC).CMAS attack significantly alters the temperature and stress fields in TBC,resulting in their delamination or spallation.In this work,the evolution process of TBC prepared by suspension plasma spraying(SPS)under CMAS attack is investigated.The CMAS corrosion leads to the formation of the reaction layer and subsequent bending of TBC.Based on the observations,a corrosion model is proposed to describe the generation and evolution of the reaction layer and bending of TBC.Then,numerical simulations are performed to investigate the corrosion process of free-standing TBC and the complete TBC system under CMAS attack.The corrosion model constructs a bridge for connecting two numerical models.The results show that the CMAS corrosion has a significant influence on the stress field,such as the peak stress,whereas it has little influence on the steady-state temperature field.The peak of stress increases with holding time,which increases the risk of the rupture of TBC.The Mises stress increases nonlinearly along the thick direction of the reaction layer.Furthermore,in the traditional failure zone,such as the interface of the top coat and bond coat,the stress obviously changes during CMAS corrosion.
文摘Trajectory tracking control of space robots in task space is of great importance to space missions, which require on-orbit manipulations. This paper focuses on position and attitude tracking control of a tree-floating space robot in task space. Since nei- ther the nonlinear terms and parametric uncertainties of the dynamic model, nor the external disturbances are known, an adap- tive radial basis function network based nonsingular terminal sliding mode （RBF-NTSM） control method is presented. The proposed algorithm combines the nonlinear sliding manifold with the radial basis function to improve control performance. Moreover, in order to account for actuator physical constraints, a constrained adaptive RBF-NTSM, which employs a RBF network to compensate for the limited input is developed. The adaptive updating laws acquired by Lyapunov approach guar- antee the global stability of the control system and suppress chattering problems. Two examples are provided using a six-link free-floating space robot. Simulation results clearly demonstrate that the proposed constrained adaptive RBF-NTSM control method performs high precision task based on incomplete dynamic model of the space robots. In addition, the control errors converge faster and the chattering is eliminated comparing to traditional sliding mode control.
基金supported by the National Natural Science Foundation of China(82173762,China)the Key Research and Development Program of Science and Technology Department of Sichuan Province(2022JDJQ0050,China)the Fundamental of Research Funds for the Central Universities.
文摘A major challenge facing photodynamic therapy(PDT) is that the activity of the immuneinduced infiltrating CD8^(+)T cells is subject to the regulatory T lymphocytes(Tregs), leaving the tumor at risk of recurrence and metastasis after the initial ablation. To augment the antitumor response and reprogram the immunosuppressive tumor microenvironment(TME), a supramolecular photodynamic nanoparticle(DACss) is constructed by the host-guest interaction between demethylcantharidin-conjugated β-cyclodextrin(DMC-CD) and amantadine-terminated disulfide-conjugated FFVLGGGC peptide with chlorin e6 decoration(Ad-ss-pep-Ce6) to achieve intelligent delivery of photosensitizer and immunomodulator for breast cancer treatment. The acid-labile β-carboxamide bond of DMC-CD is hydrolyzed in response to the acidic TME, resulting in the localized release of DMC and subsequent inhibition of Tregs.The guest molecule Ad-ss-pep-Ce6 can be cleaved by a high level of intracellular GSH, reducing photosensitizer toxicity and increasing photosensitizer retention in the tumor. With a significant increase in the CTL/Treg ratio, the combination of Ce6-based PDT and DMC-mediated immunomodulation adequately achieved spatiotemporal regulation and remodeling of the TME, as well as improved primary tumor and in situ lung metastasis suppression with the aid of PD-1 antibody.
基金supported by the National Natural Science Foundation of China(Nos.12034002,22279044,and 22202080)the Jilin Province Science and Technology Development Program(No.20210301009GX)+5 种基金Research Grant Council of Hong Kong(No.15304023)National Natural Science Foundation of China/Research Grant Council of Hong Kong Joint Research Scheme(No.N_PolyU502/21)National Natural Science Foundation of China/Research Grants Council of Hong Kong Collaborative Research Scheme(No.CRS_PolyU504/22)the funding for Projects of Strategic Importance of The Hong Kong Polytechnic University(Project Code:1-ZE2V)Shenzhen Fundamental Research Scheme-General Program(No.JCYJ20220531090807017)Natural Science Foundation of Guangdong Province(No.2023A1515012219).
文摘The development of high-performance atomiccatalysts for the carbon dioxide reduction reaction(CO_(2)RR)is atime-consuming process due to the complexity of the reactionmechanism and the uncertainty of the active site.Herein,wehave proposed combining density functional theory(DFT)andmachine learning(ML)to investigate the potential of topologicalgraphene-based dual-atom catalysts(DACs)as CO_(2)RRelectrocatalysts.By analyzing the ML results,we identify thenumber of d-orbital electrons in the active site as a key factorinfluencing the CO_(2)RR catalytic activity.Additionally,wepropose a simple descriptor to measure the CO_(2)RR activity ofthese DACs.Our findings provide plausible explanations for thesynergistic interactions between bimetallic atoms in CO_(2)RR andallow us to screen the homogeneous Ni-Ni pair as the mostpromising dual-atom catalysts.This work offers a fast MLapproach based on limited DFT calculations to predict the mostelectroactive and stable DACs on carbon support for CO_(2)RR,facilitating rapid screening of high-performance dual-atomcatalysts.
基金supported by the National Natural Science Foundation of China(Nos.12034002,22279044,and 22202080)Jilin Province Science and Technology Development Program(No.20210301009GX)the fellowship of China Postdoctoral Science Foundation(No.2022M711296).
文摘Designing high-performance electrocatalysts toward hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)is essential to reduce the activation barrier and optimize free adsorption energy of reactive intermediates.Herein,we report that incorporating high-valence Cr into NiSe_(2)(Cr_(x)Ni_(1-x)Se_(2))kinetically and thermodynamically expedites elementary steps of both HER and OER.The as-prepared Cr_(0.05)Ni_(0.95)Se_(2) catalyst displays excellent HER and OER activities,with low overpotentials of 89 and 272 mV at the current density of 10 mA·cm^(-2)(j10),respectively,and remains stable during operation for 30 h.A low cell voltage of only 1.59 V is required to drive j10 in alkaline media.In situ Raman spectroscopy reveals that Cr incorporation facilitates the formation of NiOOH active species during the OER process.Meanwhile,theoretical explorations demonstrate that high-valence Cr incorporation efficiently accelerates water dissociation kinetics and improves H*adsorption during HER process,lowering the activation barrier of OER and optimizing the adsorption energy of oxygen-based intermediate,thus kinetically and thermodynamically enhancing the intrinsic performance of NiSe_(2) for over water splitting.This strategy provides a new horizon to design transition metal based electrocatalysts in the clean energy field.
基金supported by the National Key Research and Development Plan(Grant No.2021YFB3901000)the Chinese Academy of Sciences Project for Young Scientists in Basic Research(YSBR-037)+2 种基金the International Partnership Program of the Chinese Academy of Sciences(060GJHZ2022070MI)the MOST-ESA Dragon-5 Programme for Monitoring Greenhouse Gases from Space(ID.59355)the Finland–China Mobility Cooperation Project funded by the Academy of Finland(No.348596)。
文摘In this study,we introduce our newly developed measurement-fed-perception self-adaption Low-cost UAV Coordinated Carbon Observation Network(LUCCN)prototype.The LUCCN primarily consists of two categories of instruments,including ground-based and UAV-based in-situ measurement.We use the GMP343,a low-cost non-dispersive infrared sensor,in both ground-based and UAV-based instruments.The first integrated measurement campaign took place in Shenzhen,China,4 May 2023.During the campaign,we found that LUCCN’s UAV component presented significant data-collecting advantages over its ground-based counterpart owing to the relatively high altitudes of the point emission sources,which was especially obvious at a gas power plant in Shenzhen.The emission flux was calculated by a crosssectional flux(CSF)method,the results of which differed from the Open-Data Inventory for Anthropogenic Carbon dioxide(ODIAC).The CSF result was slightly larger than others because of the low sampling rate of the whole emission cross section.The LUCCN system will be applied in future carbon monitoring campaigns to increase the spatiotemporal coverage of carbon emission information,especially in scenarios involving the detection of smaller-scale,rapidly varying sources and sinks.
