Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the...Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the reporting quality of ACR-AEs remains unclear.We aimed to promote the application of the CARE(case report)guidelines and improve the reporting quality of ACR-AEs.Methods:We systematically searched for ACR-AE from six databases:Medline,Embase,Chinese Biomedical Literature Service System,China National Knowledge Infrastructure,Wanfang Data,and VIP,and collected published ACR-AEs from January 1,2016,to December 31,2020.We included only case reports of adverse events related to acupuncture therapy.The retrieved case reports were screened and filtered by two reviewers independently.Then,basic information extraction and CARE evaluation of the included ACR-AEs wereperformed.Results:A total of 56 ACR-AE were included,15 of which were from China.The top two major diseases were nervous system diseases(28.6%)and infections(21.4%).For all ACR-AEs,seven of 30 CARE subordinate items were reported in 30%or less,seven items were reported in 30-60%,and only five items got reporting proportion over 90%.In Chinese ACR-AE,only three items,"the main concerns and symptoms of the patient(5b)","types of intervention(9a)"and"adverse and unanticipated events(1od)"were sufficiently reported.In English ACR-AE,item"the main concerns and symptoms of the patient(5b)"and item"the primary takeaway lessons(11d)"were also generally reported.Conclusion:Overall,the reporting quality of ACR-AE was unsatisfactory,and we believe that a special reporting guideline for clinical cases targeted at acupuncture should be extended in future studies.展开更多
We have used the ShenguangⅡlaser in third harmonic(351 nm)to investigate the emission of L-shell radiation in the 3.3–4.4 ke V range generated using thin foils of Sn coated onto a parylene substrate with irradiation...We have used the ShenguangⅡlaser in third harmonic(351 nm)to investigate the emission of L-shell radiation in the 3.3–4.4 ke V range generated using thin foils of Sn coated onto a parylene substrate with irradiation of order 1015 W cm-2 and nanosecond pulse duration.In our experiment,we have concentrated on assessing the emission on the non-laser irradiated side as this allows an experimental geometry relevant to experiments on photo-ionised plasmas where a secondary target must be placed close to the source,to achieve x-ray fluxes appropriate to astrophysical objects.Overall L-shell conversion efficiencies are estimated to be of order 1%,with little dependence on Sn thickness between 400 and 800 nm.展开更多
基金Supported by Special Project of "Lingnan Modernization of Traditional Chinese Medicine" in 2019,Guangdong Provincial R&D Program:2020B1111100008Young Science and Technology Talents Fund of The Affiliated TCM Hospital of Guangzhou Medical University:2022RC07
文摘Objective:As a popular complementary therapy,the safety of acupuncture must be considered.Acupuncture case reports of adverse events(ACR-AEs)significantly contribute to the assessment of acupuncture safety.However,the reporting quality of ACR-AEs remains unclear.We aimed to promote the application of the CARE(case report)guidelines and improve the reporting quality of ACR-AEs.Methods:We systematically searched for ACR-AE from six databases:Medline,Embase,Chinese Biomedical Literature Service System,China National Knowledge Infrastructure,Wanfang Data,and VIP,and collected published ACR-AEs from January 1,2016,to December 31,2020.We included only case reports of adverse events related to acupuncture therapy.The retrieved case reports were screened and filtered by two reviewers independently.Then,basic information extraction and CARE evaluation of the included ACR-AEs wereperformed.Results:A total of 56 ACR-AE were included,15 of which were from China.The top two major diseases were nervous system diseases(28.6%)and infections(21.4%).For all ACR-AEs,seven of 30 CARE subordinate items were reported in 30%or less,seven items were reported in 30-60%,and only five items got reporting proportion over 90%.In Chinese ACR-AE,only three items,"the main concerns and symptoms of the patient(5b)","types of intervention(9a)"and"adverse and unanticipated events(1od)"were sufficiently reported.In English ACR-AE,item"the main concerns and symptoms of the patient(5b)"and item"the primary takeaway lessons(11d)"were also generally reported.Conclusion:Overall,the reporting quality of ACR-AE was unsatisfactory,and we believe that a special reporting guideline for clinical cases targeted at acupuncture should be extended in future studies.
基金supported by the UK Science and Technology Facilities Council,National Natural Science Foundation of China(No.11573040)Science Challenge Project(No.TZ2016005)The Royal Society International Exchange(No.IE161039).
文摘We have used the ShenguangⅡlaser in third harmonic(351 nm)to investigate the emission of L-shell radiation in the 3.3–4.4 ke V range generated using thin foils of Sn coated onto a parylene substrate with irradiation of order 1015 W cm-2 and nanosecond pulse duration.In our experiment,we have concentrated on assessing the emission on the non-laser irradiated side as this allows an experimental geometry relevant to experiments on photo-ionised plasmas where a secondary target must be placed close to the source,to achieve x-ray fluxes appropriate to astrophysical objects.Overall L-shell conversion efficiencies are estimated to be of order 1%,with little dependence on Sn thickness between 400 and 800 nm.