As an important ecological tree species in northern China, Populus simonii plays a crucial role in maintaining ecological balance and promoting environmental sustainability. The academic community has conducted a seri...As an important ecological tree species in northern China, Populus simonii plays a crucial role in maintaining ecological balance and promoting environmental sustainability. The academic community has conducted a series of in-depth studies on this species, covering key areas such as genomics, survival mechanisms, and genetic breeding. Through the analysis of the genomic structure and function of P. simonii, we have not only revealed the molecular basis for its adaptation to harsh environments but also identified key genes that promote its growth and resistance to pests and diseases. Furthermore, exploring the survival mechanisms of P. simonii has deepened our understanding of its stress resistance traits, including how it effectively copes with abiotic stresses such as drought, salinization, and heavy metal pollution. In genetic breeding, significant progress has been made through the application of modern biotechnology, improving the growth rate and wood quality of P. simonii and enhancing its environmental adaptability and disease resistance. These research findings have not only enriched our knowledge of the biological characteristics of P. simonii but also provided a solid scientific foundation for its application in ecological restoration, forestry production, and environmental management.展开更多
针对内充气吹式排种器组合气嘴低位安装对供气系统气流稳定性要求高、田间作业适应性差的问题,为优化内充气吹式排种器结构、改善工作性能,运用EDEM-CFD耦合分析方法,采用玉米籽粒粘结颗粒模型,以气嘴安装位置、工作压强和前进速度为试...针对内充气吹式排种器组合气嘴低位安装对供气系统气流稳定性要求高、田间作业适应性差的问题,为优化内充气吹式排种器结构、改善工作性能,运用EDEM-CFD耦合分析方法,采用玉米籽粒粘结颗粒模型,以气嘴安装位置、工作压强和前进速度为试验因素进行正交试验优化仿真,提取关键参数充种极限速度和充种时长为评价指标进行分析,结果表明气嘴安装位置、工作压强和前进速度对充种极限速度影响显著而对充种时长影响不显著,充种极限速度和充种时长在0.05水平上呈显著负相关关系,较大充种极限速度和较短充种时长有利于提高排种器充种性能;对不同作业状态下的合格率、重播率、漏播率等作业指标进行分析表明气嘴安装位置在中位时合格率和充种极限速度呈显著正相关,低位和高位时因清种效果不佳导致合格率和充种极限速度呈负相关,中位时排种效果较佳。为验证仿真结果,进行气嘴安装位置和工作压强的全因素试验,结果表明,气嘴安装位置为中位时作业效果最佳,合格率大于90%,明显优于低位、高位状态,与仿真结果一致;在确定组合气嘴中位安装结构参数下,进行工作压强、前进速度的全因素试验,结果表明,前进速度为5~10 km/h、工作压强为4.5~5.5 k Pa时,排种器合格率较高,均为90%以上,该区间各工作参数下对合格率影响不显著。展开更多
结直肠癌(colorectal cancer,CRC)是受遗传与环境因素共同影响的复杂疾病,其中遗传因素发挥重要作用。至今,全基因组关联研究(genome-wide association studies,GWAS)已经发现了大量与结直肠癌风险相关的遗传变异。随之而来的后GWAS时代...结直肠癌(colorectal cancer,CRC)是受遗传与环境因素共同影响的复杂疾病,其中遗传因素发挥重要作用。至今,全基因组关联研究(genome-wide association studies,GWAS)已经发现了大量与结直肠癌风险相关的遗传变异。随之而来的后GWAS时代,越来越多的研究侧重于利用多组学数据和功能实验对潜在的致病位点进行解析。分析表明绝大多数风险单核苷酸多态性(single nucleotide polymorphism,SNP)位于非编码区,可能通过影响转录因子结合、表观遗传修饰、染色质可及性、基因组高级结构等,调控靶基因表达。本文对后GWAS时代结直肠癌致病位点的机制研究进行综述,阐述了后GWAS对于理解结直肠癌分子机制的重要意义,并探讨了结直肠癌GWAS的应用和前景,为实现GWAS成果转化提供参考。展开更多
文摘As an important ecological tree species in northern China, Populus simonii plays a crucial role in maintaining ecological balance and promoting environmental sustainability. The academic community has conducted a series of in-depth studies on this species, covering key areas such as genomics, survival mechanisms, and genetic breeding. Through the analysis of the genomic structure and function of P. simonii, we have not only revealed the molecular basis for its adaptation to harsh environments but also identified key genes that promote its growth and resistance to pests and diseases. Furthermore, exploring the survival mechanisms of P. simonii has deepened our understanding of its stress resistance traits, including how it effectively copes with abiotic stresses such as drought, salinization, and heavy metal pollution. In genetic breeding, significant progress has been made through the application of modern biotechnology, improving the growth rate and wood quality of P. simonii and enhancing its environmental adaptability and disease resistance. These research findings have not only enriched our knowledge of the biological characteristics of P. simonii but also provided a solid scientific foundation for its application in ecological restoration, forestry production, and environmental management.
文摘针对内充气吹式排种器组合气嘴低位安装对供气系统气流稳定性要求高、田间作业适应性差的问题,为优化内充气吹式排种器结构、改善工作性能,运用EDEM-CFD耦合分析方法,采用玉米籽粒粘结颗粒模型,以气嘴安装位置、工作压强和前进速度为试验因素进行正交试验优化仿真,提取关键参数充种极限速度和充种时长为评价指标进行分析,结果表明气嘴安装位置、工作压强和前进速度对充种极限速度影响显著而对充种时长影响不显著,充种极限速度和充种时长在0.05水平上呈显著负相关关系,较大充种极限速度和较短充种时长有利于提高排种器充种性能;对不同作业状态下的合格率、重播率、漏播率等作业指标进行分析表明气嘴安装位置在中位时合格率和充种极限速度呈显著正相关,低位和高位时因清种效果不佳导致合格率和充种极限速度呈负相关,中位时排种效果较佳。为验证仿真结果,进行气嘴安装位置和工作压强的全因素试验,结果表明,气嘴安装位置为中位时作业效果最佳,合格率大于90%,明显优于低位、高位状态,与仿真结果一致;在确定组合气嘴中位安装结构参数下,进行工作压强、前进速度的全因素试验,结果表明,前进速度为5~10 km/h、工作压强为4.5~5.5 k Pa时,排种器合格率较高,均为90%以上,该区间各工作参数下对合格率影响不显著。
