AIM:To compare genotype of Helicobacter pylori(H.pylori) isolated from saliva,dental plaques,gastric biopsy,and stool of each patient in order to evaluate the mode of transmission of H.pylori infection.METHODS:This cr...AIM:To compare genotype of Helicobacter pylori(H.pylori) isolated from saliva,dental plaques,gastric biopsy,and stool of each patient in order to evaluate the mode of transmission of H.pylori infection.METHODS:This cross-sectional descriptive study was performed on 300 antral gastric biopsy,saliva,dental plaque and stool samples which were obtained from patients undergoing upper gastrointestinal tract endoscopy referred to endoscopy centre of Hajar hospital of Shahrekord,Iran from March 2010 to February 2011.Initially,H.pylori strains were identified by rapid urease test(RUT) and polymerase chain reaction(PCR) were applied to determine the presence of H.pylori(ureC) and for genotyping of voculating cytotoxin gene A(vacA) and cytotoxin associated gene A(cagA) genesin each specimen.Finally the data were analyzed by using statistical formulas such as Chi-square and Fisher's exact tests to find any significant relationship between these genes and patient's diseases.P < 0.05 was considered statistically significant,RESULTS:Of 300 gastric biopsy samples,77.66% were confirmed to be H.pylori positive by PCR assay while this bacterium were detected in 10.72% of saliva,71.67% of stool samples.We were not able to find it in dental plaque specimens.The prevalence of H.pylori was 90.47% among patients with peptic ulcer disease(PUD),80% among patients with gastric cancer,and 74.13% among patients with none ulcer dyspepsia(NUD) by PCR assay.The evaluation of vacA and cagA genes showed 6 differences between gastric biopsy and saliva specimens and 11 differences between gastric and stool specimens.94.42% of H.pylori positive specimens were cagA positive and all samples had amplified band both for vacA s and m regions.There was significant relationship between vacA s1a/m1a and PUD diseases(P = 0.04),s2/m2 genotype and NUD diseases(P = 0.05).No statically significant relationship was found between cagA status with clinical outcomes and vacA genotypes(P = 0.65).The evaluation of vacA and cagA genes showed 6 differences between gastr展开更多
The occurrence of the historical and machine Earthquakes, near to the North Tabriz Fault in NW Iran is an evidence for the seismic activity of this fault, which records a historical earthquake with a magnitude more th...The occurrence of the historical and machine Earthquakes, near to the North Tabriz Fault in NW Iran is an evidence for the seismic activity of this fault, which records a historical earthquake with a magnitude more than 7. Using the existing experimental relations, seismicity, and the fault geometry, a Mw 7.7 earthquake scenario was defined. The stochastic finite-fault modeling based on a dynamic corner frequency shows good agreement with common attenuation patterns. The shake map illustrates that Baghmisheh, Roshtieh, Ellahieh, Valiamr, and Eram region on Tabriz are at high hazard areas, and the maximum acceleration is located at the north direction with the same azimuth similar to fault strike.展开更多
In this paper, tectonic and geothermobarometric environments have been studied with respect to the combination of pyroxene, olivine and plagioclase in volcanic rocks in the southeast of Bam. The combination of volcani...In this paper, tectonic and geothermobarometric environments have been studied with respect to the combination of pyroxene, olivine and plagioclase in volcanic rocks in the southeast of Bam. The combination of volcanic rocks in the region consists of olivine basalt, basalt, alkaline basalt, andesite, trachyandesite and pyroxene andesite. This combination is the result of the processes of crystallization and sometimes contamination. Plagioclase, clinopyroxene, olivine, and amphibole constitute the major minerals (rock forming minerals) in these rocks. Porphyritic to mega-porphyritic textures with microlithic, glumero-porphyritic and amigdaluidal matrix are observed. Based on the thermometric calculations, plagioclase, pyroxene, and olivine minerals and the rocks of this region are crystallized at a pressure of 1.5 to 7 kb and temperatures ranging from about 700°C to 1250°C.展开更多
Objective. The purpose of this study was to characterizethe number and distribution of epidermal Langerhans cells in different clinical forms of dry-type cutaneous leishmaniasis (CL). Methods. Sixteen cases of dry-typ...Objective. The purpose of this study was to characterizethe number and distribution of epidermal Langerhans cells in different clinical forms of dry-type cutaneous leishmaniasis (CL). Methods. Sixteen cases of dry-type cutaneous leishmaniasis caused by Leishmania tropica were studied. These cases were classified clinically as five cases of acute leishmaniasis with indurated papules, nodules and plaques with central crust formation and duration < 2years,sixcasesoflupoidleishmaniasis with characteristic papules around previous scars of cutaneous leishmaniasis with duration >2 years, and five cases of chronic nonlupoid type with nonhealing lesions of duration >2 years. Paraffin-embedded blocks were stained with hematoxylin and eosin (H&E) and stained immunohistochemically for CD1a. Results. The number of Langerhans cells per millimeter length of epidermis was increased in acute cases compared to chronic and lupoid cases. Conclusions. Lesions of acute leishmaniasis contain the greatest amounts of antigen for presentation, so Langerhans cells increase innumber and intrafficking to present antigens derived from Leishman bodies to the cellular immune system. In chronic leishmaniasis, the Langerhans cell population is reduced, perhaps because of exhaustion of the source of Langerhans cells, or because of reduced response to modified antigen.展开更多
Developed in this paper is a traffic flow model parametrised to describe abnormal traffic behaviour.In large traffic networks,the immediate detection and categorisation of traffic incidents/accidents is of capital imp...Developed in this paper is a traffic flow model parametrised to describe abnormal traffic behaviour.In large traffic networks,the immediate detection and categorisation of traffic incidents/accidents is of capital importance to avoid breakdowns,further accidents.First,this claims for traffic flow models capable to capture abnormal traffic condition like accidents.Second,by means of proper real-time estimation technique,observing accident related parameters,one may even categorize the severity of accidents.Hence,in this paper,we suggest to modify the nominal Aw-Rascle(AR)traffic model by a proper incident related parametrisation.The proposed Incident Traffic Flow(ITF)model is defined by introducing the incident parameters modifying the anticipation and the dynamic speed relaxation terms in the speed equation of the AR model.These modifications are proven to have physical meaning.Furthermore,the characteristic properties of the ITF model is discussed in the paper.A multi stage numerical scheme is suggested to discretise in space and time the resulting non-homogeneous system of PDEs.The resulting systems of ODE is then combined with receding horizon estimation methods to reconstruct the incident parameters.Finally,the viability of the suggested incident parametrisation is validated in a simulation environment.展开更多
Petrography and chemistry of minerals show that rocks of Upper Eocene in northeast of Tafresh are composed mostly of andesitic basalt, basaltic andesite and andesite volcanic rocks. Mineralogically these rocks are com...Petrography and chemistry of minerals show that rocks of Upper Eocene in northeast of Tafresh are composed mostly of andesitic basalt, basaltic andesite and andesite volcanic rocks. Mineralogically these rocks are composed of phenocrystals of olivine, clinopyroxene and plagioclase and main texture of them is porphyry with cryptocrystalline or microcrystalline matrix. In addition, aphyric and pitted textures (amygdala) are also observed. According to the results of EPMA, phenocrystals of plagioclase in mentioned rocks include a range of anorthite to albite minerals. Alkali feldspars also contain a range of sodic to potassic minerals. Pyroxene crystals include hedenbergite, augite and hypersthene. Olivine minerals are often of the ferrohornblendite type. Based on thermobarometry it is estimated that to form clinopyroxene crystals of basaltic andesite rocks, temperature between 750°C to 1000°C is needed. Andesitic basalt rocks at higher temperature (1100°C) and andesite rocks at lower temperature (below 750°C) are formed. According to the distribution of aluminum in clinopyroxenes, these minerals at pressures less than 5 kbar and water content between 5% to 10% are crystallized. The mineral composition indicates that these rocks are formed in a tensional environment.展开更多
Objective: To determine the susceptibility status of Anopheles maculipennis(An. maculipennis) against the major insecticides used in the health sectors in West Azarbaijan Province, Northwestern Iran.Methods: Unfed 3-5...Objective: To determine the susceptibility status of Anopheles maculipennis(An. maculipennis) against the major insecticides used in the health sectors in West Azarbaijan Province, Northwestern Iran.Methods: Unfed 3-5 days old adult females of An. maculipennis were collected across the West Azarbaijan Province and were subjected to evaluation of their susceptibility following World Health Organization recommended protocol against six insecticides(permethrin, deltamethrin, propoxur, bendiocarb, malathion and dieldrin) belonging to four different classes. Results: In this study, 916 specimens of An. maculipennis were examined against the insecticides which indicated that An. maculipennis was tolerant to permethrin, deltamethrin and dielderin, but displayed resistance against propoxur, bendiocarb and malathion. Conclusions: The pattern of resistance in An. maculipennis could be attributed to the agricultural landscapes, agricultural pesticides used and the exposure of the mosquitoes to insecticides. Logical cooperation is needed between the agriculture and health sectors to ensure the judicious use of pesticides in each sector and the management of probable resistance.展开更多
This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bah...This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bahonar University of Kerman with a 5.5×3.5 centimeter pedunculated mass on its head near left auricular region which had been progressively growing since tliree months ago.The radiography showed no local and distant metastasis.Surgical excision and histological evaluation was done.Histologically,the mass was composed of epithelial cells arranged in glandular and solid patterns.The morphologic findings suggested either a primary or metastatic apocrine-gland carcinoma.Immunohistochemically,the tumor cells were intensely positive for cytokeratin 7 and 20 and negative for S100 protein.On the basis of histopathological and clinical findings,the tumor was diagnosed as a malignant apocrine gland tumor,arising from apocrine sweat glands of the skin.Local tumor recurrence with anorexia and weight loss was reported by the owner nine month later.Severe submandibular and prescapular lymphadenomegaly was noted in clinical examination.Several large pulmonary nodules were noted in chest radiographs resembling mediastinal lymph node metastasis.Second surgery and chemotherapy was rejected by the owner due to grave prognosis of the patient.The animal was died 45 days later due to respiratory complications.Tumors of apocrine sweat glands are relatively uncommon in dogs whereas apocrine gland adenocarcinoma with distant metastasis is extremely rare.展开更多
In the present era, water contamination represents one of the considerable environmental problems. Population growth along with ever increasing industrial developments has resulted in the contamination of most of the ...In the present era, water contamination represents one of the considerable environmental problems. Population growth along with ever increasing industrial developments has resulted in the contamination of most of the water resources in the world, bringing about serious problems for humans and other living organisms. According to the human life on earth depends on the way different water resources are exploited, the most important way to preserve the quality of water resources is to codify appropriate regulations and standards and develop plans for proper and principled implementation of them. Therefore, it seems to be necessary to take required actions to manage water resources optimally. In this regard, one of the most significant legal tools is the law. Following a descriptive-analytic approach, the present research aims to consider legal challenges in the context of water contamination briefly. Investigations indicate that, given the limitations in water resources, in future, water contamination will raise serious problems for the country should the solutions and measures required for tackling this issue are not well incorporated into respective regulations. As such, in order to systemize the activities within this scope, it is necessary to codify a comprehensive act about different water-related topics, so as to cover all separate and sparse pieces of regulations on water. Further, acquiring help from experts when preparing the regulations with an emphasis on the inhibitory role of penalties, roles of NGOs and culture-making in the society will contribute to the successful legal protection of the quality of water resources.展开更多
The KoheSiah Volcanoes are located in the North of Qorveh city in the west of Iran. The KoheSiah volcanoes include several craters bearing domes located in the Kordestan Province, between latitudes 35°23'...The KoheSiah Volcanoes are located in the North of Qorveh city in the west of Iran. The KoheSiah volcanoes include several craters bearing domes located in the Kordestan Province, between latitudes 35°23'13.54” to 35°21'26.63”N and longitudes 47°54'38.26”E to 47°56'01.42”E. Based on the petrographic and geochemical analysis, the volcanic rocks in the KoheSiah area are classified as basalt, Alkali basalt, trachy-andesites and mugearite. The studied samples are alkaline with sodic to potasic feature based on Na2O/K2O ratios and belonging to Shoshonite series. Most of the alkaline volcanic rocks in the study area fall in the field of within in plate basalts (WPB) and represent of a mantle metasomatism trend associated with variable degrees in the partial melting of an enriched mantle source.展开更多
Cell membrane rupture is considered to be one of the probable mechanisms for bacterial inactivation using barrier corona discharge （BCD） plasma. In this paper, the effect of the BCD plasma on the Escherichia coli （...Cell membrane rupture is considered to be one of the probable mechanisms for bacterial inactivation using barrier corona discharge （BCD） plasma. In this paper, the effect of the BCD plasma on the Escherichia coli （E. coli） bacteria cell wall was investigated through two analytical methods; Adenosine-5-triphosphate （ATP） assay and Atomic Force Microscopy （AFM）. The ATP assay results indicate an increase in the ATP content of samples which were exposed to the BCD plasma. This implies the bacteria cell rupture. Moreover, AFM images confirm a serious damage of the bacteria cell wall under the influence of the bactericidal agents of the plasma.展开更多
The Jalal-Abad iron ore deposit, with a reserve of more than 200 Mt ore, is located in NW of Zarand region, southeastern Iran. The ore deposit occurs in the form of an elongated lens-shaped body incorporated in a fold...The Jalal-Abad iron ore deposit, with a reserve of more than 200 Mt ore, is located in NW of Zarand region, southeastern Iran. The ore deposit occurs in the form of an elongated lens-shaped body incorporated in a folded structure of Rizu volcano-sedimentary unit. Mineralization occurred mainly in siltstones, acidic volcanic rocks and dolomitized limestones. The ore minerals include magnetite, hematite, pyrite, chalcopyrite, goethite, malachite and azurite. Chloritization and silicification are the two most widespread alteration types in the Jalal-Abad area. Cu and Ti are among the associated elements with iron in the ore samples. In comparison, the concentrations of Cu, Ti and REE are relatively low in the samples analyzed. The combined concentrations of Ce, La and Y show that geochemical background values for most areas have been measured. The Pearson correlation coefficient values and the results of cluster and principal component analyses indicate a strong correlation between REE, La, Ce, and Y with Sr in the same geochemical group suggesting a common source for these elements. A close association between Cu and Cl with metasomatic host rock and among Pb, Zn and Ba with carbonate host rocks is observed.展开更多
Objective:To explore the anti-inflammatory and antioxidant effects of caraway on atopic dermatitis(AD)in mice.Methods:AD was induced in two stages,including sensitization and challenge with the application of 2,4 dini...Objective:To explore the anti-inflammatory and antioxidant effects of caraway on atopic dermatitis(AD)in mice.Methods:AD was induced in two stages,including sensitization and challenge with the application of 2,4 dinitrochlorobenzene 2% and 0.2%,respectively.Clinical symptoms and histological analysis of the skin were assessed.The effects of caraway on oxidant/antioxidant parameters as well as Th1-and Th2-related cytokines were also evaluated.Results:Caraway reduced the severity of dermatitis in AD-induced mice,as evidenced by significant inhibition of Th2-related cytokines(IL-4 and IL-13)and increased Th1-related cytokine(IFN-γ).Additionally,treatment with caraway significantly increased superoxide dismutase and catalase activity and decreased the malondialdehyde level in the serum of AD mice.Furthermore,caraway inhibited the differentiation of Th2 cells while favoring Th1 cell differentiation in the spleen via regulating their master transcription factors GATA3 and T-bet.Conclusions:Caraway could improve AD autoimmune responses and could be considered a potential candidate to treat AD disease.展开更多
基金Supported by The Islamic Azad University,Shahre Kord Branch-Iran grant 89/8761
文摘AIM:To compare genotype of Helicobacter pylori(H.pylori) isolated from saliva,dental plaques,gastric biopsy,and stool of each patient in order to evaluate the mode of transmission of H.pylori infection.METHODS:This cross-sectional descriptive study was performed on 300 antral gastric biopsy,saliva,dental plaque and stool samples which were obtained from patients undergoing upper gastrointestinal tract endoscopy referred to endoscopy centre of Hajar hospital of Shahrekord,Iran from March 2010 to February 2011.Initially,H.pylori strains were identified by rapid urease test(RUT) and polymerase chain reaction(PCR) were applied to determine the presence of H.pylori(ureC) and for genotyping of voculating cytotoxin gene A(vacA) and cytotoxin associated gene A(cagA) genesin each specimen.Finally the data were analyzed by using statistical formulas such as Chi-square and Fisher's exact tests to find any significant relationship between these genes and patient's diseases.P < 0.05 was considered statistically significant,RESULTS:Of 300 gastric biopsy samples,77.66% were confirmed to be H.pylori positive by PCR assay while this bacterium were detected in 10.72% of saliva,71.67% of stool samples.We were not able to find it in dental plaque specimens.The prevalence of H.pylori was 90.47% among patients with peptic ulcer disease(PUD),80% among patients with gastric cancer,and 74.13% among patients with none ulcer dyspepsia(NUD) by PCR assay.The evaluation of vacA and cagA genes showed 6 differences between gastric biopsy and saliva specimens and 11 differences between gastric and stool specimens.94.42% of H.pylori positive specimens were cagA positive and all samples had amplified band both for vacA s and m regions.There was significant relationship between vacA s1a/m1a and PUD diseases(P = 0.04),s2/m2 genotype and NUD diseases(P = 0.05).No statically significant relationship was found between cagA status with clinical outcomes and vacA genotypes(P = 0.65).The evaluation of vacA and cagA genes showed 6 differences between gastr
文摘The occurrence of the historical and machine Earthquakes, near to the North Tabriz Fault in NW Iran is an evidence for the seismic activity of this fault, which records a historical earthquake with a magnitude more than 7. Using the existing experimental relations, seismicity, and the fault geometry, a Mw 7.7 earthquake scenario was defined. The stochastic finite-fault modeling based on a dynamic corner frequency shows good agreement with common attenuation patterns. The shake map illustrates that Baghmisheh, Roshtieh, Ellahieh, Valiamr, and Eram region on Tabriz are at high hazard areas, and the maximum acceleration is located at the north direction with the same azimuth similar to fault strike.
文摘In this paper, tectonic and geothermobarometric environments have been studied with respect to the combination of pyroxene, olivine and plagioclase in volcanic rocks in the southeast of Bam. The combination of volcanic rocks in the region consists of olivine basalt, basalt, alkaline basalt, andesite, trachyandesite and pyroxene andesite. This combination is the result of the processes of crystallization and sometimes contamination. Plagioclase, clinopyroxene, olivine, and amphibole constitute the major minerals (rock forming minerals) in these rocks. Porphyritic to mega-porphyritic textures with microlithic, glumero-porphyritic and amigdaluidal matrix are observed. Based on the thermometric calculations, plagioclase, pyroxene, and olivine minerals and the rocks of this region are crystallized at a pressure of 1.5 to 7 kb and temperatures ranging from about 700°C to 1250°C.
文摘Objective. The purpose of this study was to characterizethe number and distribution of epidermal Langerhans cells in different clinical forms of dry-type cutaneous leishmaniasis (CL). Methods. Sixteen cases of dry-type cutaneous leishmaniasis caused by Leishmania tropica were studied. These cases were classified clinically as five cases of acute leishmaniasis with indurated papules, nodules and plaques with central crust formation and duration < 2years,sixcasesoflupoidleishmaniasis with characteristic papules around previous scars of cutaneous leishmaniasis with duration >2 years, and five cases of chronic nonlupoid type with nonhealing lesions of duration >2 years. Paraffin-embedded blocks were stained with hematoxylin and eosin (H&E) and stained immunohistochemically for CD1a. Results. The number of Langerhans cells per millimeter length of epidermis was increased in acute cases compared to chronic and lupoid cases. Conclusions. Lesions of acute leishmaniasis contain the greatest amounts of antigen for presentation, so Langerhans cells increase innumber and intrafficking to present antigens derived from Leishman bodies to the cellular immune system. In chronic leishmaniasis, the Langerhans cell population is reduced, perhaps because of exhaustion of the source of Langerhans cells, or because of reduced response to modified antigen.
基金supported and funded by the Transport Area of Advance.
文摘Developed in this paper is a traffic flow model parametrised to describe abnormal traffic behaviour.In large traffic networks,the immediate detection and categorisation of traffic incidents/accidents is of capital importance to avoid breakdowns,further accidents.First,this claims for traffic flow models capable to capture abnormal traffic condition like accidents.Second,by means of proper real-time estimation technique,observing accident related parameters,one may even categorize the severity of accidents.Hence,in this paper,we suggest to modify the nominal Aw-Rascle(AR)traffic model by a proper incident related parametrisation.The proposed Incident Traffic Flow(ITF)model is defined by introducing the incident parameters modifying the anticipation and the dynamic speed relaxation terms in the speed equation of the AR model.These modifications are proven to have physical meaning.Furthermore,the characteristic properties of the ITF model is discussed in the paper.A multi stage numerical scheme is suggested to discretise in space and time the resulting non-homogeneous system of PDEs.The resulting systems of ODE is then combined with receding horizon estimation methods to reconstruct the incident parameters.Finally,the viability of the suggested incident parametrisation is validated in a simulation environment.
文摘Petrography and chemistry of minerals show that rocks of Upper Eocene in northeast of Tafresh are composed mostly of andesitic basalt, basaltic andesite and andesite volcanic rocks. Mineralogically these rocks are composed of phenocrystals of olivine, clinopyroxene and plagioclase and main texture of them is porphyry with cryptocrystalline or microcrystalline matrix. In addition, aphyric and pitted textures (amygdala) are also observed. According to the results of EPMA, phenocrystals of plagioclase in mentioned rocks include a range of anorthite to albite minerals. Alkali feldspars also contain a range of sodic to potassic minerals. Pyroxene crystals include hedenbergite, augite and hypersthene. Olivine minerals are often of the ferrohornblendite type. Based on thermobarometry it is estimated that to form clinopyroxene crystals of basaltic andesite rocks, temperature between 750°C to 1000°C is needed. Andesitic basalt rocks at higher temperature (1100°C) and andesite rocks at lower temperature (below 750°C) are formed. According to the distribution of aluminum in clinopyroxenes, these minerals at pressures less than 5 kbar and water content between 5% to 10% are crystallized. The mineral composition indicates that these rocks are formed in a tensional environment.
基金Supported by Urmia University of Medical Sciences,Urmia,Iran(Project No.1239)
文摘Objective: To determine the susceptibility status of Anopheles maculipennis(An. maculipennis) against the major insecticides used in the health sectors in West Azarbaijan Province, Northwestern Iran.Methods: Unfed 3-5 days old adult females of An. maculipennis were collected across the West Azarbaijan Province and were subjected to evaluation of their susceptibility following World Health Organization recommended protocol against six insecticides(permethrin, deltamethrin, propoxur, bendiocarb, malathion and dieldrin) belonging to four different classes. Results: In this study, 916 specimens of An. maculipennis were examined against the insecticides which indicated that An. maculipennis was tolerant to permethrin, deltamethrin and dielderin, but displayed resistance against propoxur, bendiocarb and malathion. Conclusions: The pattern of resistance in An. maculipennis could be attributed to the agricultural landscapes, agricultural pesticides used and the exposure of the mosquitoes to insecticides. Logical cooperation is needed between the agriculture and health sectors to ensure the judicious use of pesticides in each sector and the management of probable resistance.
文摘This report describes the clinical and pathological aspects of an apocrine sweat gland carcinoma with distant metastasis in an aged dog.A 7-year-old male terrier dog was referred to small animal hospital of Shuhid Bahonar University of Kerman with a 5.5×3.5 centimeter pedunculated mass on its head near left auricular region which had been progressively growing since tliree months ago.The radiography showed no local and distant metastasis.Surgical excision and histological evaluation was done.Histologically,the mass was composed of epithelial cells arranged in glandular and solid patterns.The morphologic findings suggested either a primary or metastatic apocrine-gland carcinoma.Immunohistochemically,the tumor cells were intensely positive for cytokeratin 7 and 20 and negative for S100 protein.On the basis of histopathological and clinical findings,the tumor was diagnosed as a malignant apocrine gland tumor,arising from apocrine sweat glands of the skin.Local tumor recurrence with anorexia and weight loss was reported by the owner nine month later.Severe submandibular and prescapular lymphadenomegaly was noted in clinical examination.Several large pulmonary nodules were noted in chest radiographs resembling mediastinal lymph node metastasis.Second surgery and chemotherapy was rejected by the owner due to grave prognosis of the patient.The animal was died 45 days later due to respiratory complications.Tumors of apocrine sweat glands are relatively uncommon in dogs whereas apocrine gland adenocarcinoma with distant metastasis is extremely rare.
文摘In the present era, water contamination represents one of the considerable environmental problems. Population growth along with ever increasing industrial developments has resulted in the contamination of most of the water resources in the world, bringing about serious problems for humans and other living organisms. According to the human life on earth depends on the way different water resources are exploited, the most important way to preserve the quality of water resources is to codify appropriate regulations and standards and develop plans for proper and principled implementation of them. Therefore, it seems to be necessary to take required actions to manage water resources optimally. In this regard, one of the most significant legal tools is the law. Following a descriptive-analytic approach, the present research aims to consider legal challenges in the context of water contamination briefly. Investigations indicate that, given the limitations in water resources, in future, water contamination will raise serious problems for the country should the solutions and measures required for tackling this issue are not well incorporated into respective regulations. As such, in order to systemize the activities within this scope, it is necessary to codify a comprehensive act about different water-related topics, so as to cover all separate and sparse pieces of regulations on water. Further, acquiring help from experts when preparing the regulations with an emphasis on the inhibitory role of penalties, roles of NGOs and culture-making in the society will contribute to the successful legal protection of the quality of water resources.
文摘The KoheSiah Volcanoes are located in the North of Qorveh city in the west of Iran. The KoheSiah volcanoes include several craters bearing domes located in the Kordestan Province, between latitudes 35°23'13.54” to 35°21'26.63”N and longitudes 47°54'38.26”E to 47°56'01.42”E. Based on the petrographic and geochemical analysis, the volcanic rocks in the KoheSiah area are classified as basalt, Alkali basalt, trachy-andesites and mugearite. The studied samples are alkaline with sodic to potasic feature based on Na2O/K2O ratios and belonging to Shoshonite series. Most of the alkaline volcanic rocks in the study area fall in the field of within in plate basalts (WPB) and represent of a mantle metasomatism trend associated with variable degrees in the partial melting of an enriched mantle source.
文摘Cell membrane rupture is considered to be one of the probable mechanisms for bacterial inactivation using barrier corona discharge （BCD） plasma. In this paper, the effect of the BCD plasma on the Escherichia coli （E. coli） bacteria cell wall was investigated through two analytical methods; Adenosine-5-triphosphate （ATP） assay and Atomic Force Microscopy （AFM）. The ATP assay results indicate an increase in the ATP content of samples which were exposed to the BCD plasma. This implies the bacteria cell rupture. Moreover, AFM images confirm a serious damage of the bacteria cell wall under the influence of the bactericidal agents of the plasma.
文摘The Jalal-Abad iron ore deposit, with a reserve of more than 200 Mt ore, is located in NW of Zarand region, southeastern Iran. The ore deposit occurs in the form of an elongated lens-shaped body incorporated in a folded structure of Rizu volcano-sedimentary unit. Mineralization occurred mainly in siltstones, acidic volcanic rocks and dolomitized limestones. The ore minerals include magnetite, hematite, pyrite, chalcopyrite, goethite, malachite and azurite. Chloritization and silicification are the two most widespread alteration types in the Jalal-Abad area. Cu and Ti are among the associated elements with iron in the ore samples. In comparison, the concentrations of Cu, Ti and REE are relatively low in the samples analyzed. The combined concentrations of Ce, La and Y show that geochemical background values for most areas have been measured. The Pearson correlation coefficient values and the results of cluster and principal component analyses indicate a strong correlation between REE, La, Ce, and Y with Sr in the same geochemical group suggesting a common source for these elements. A close association between Cu and Cl with metasomatic host rock and among Pb, Zn and Ba with carbonate host rocks is observed.
文摘Objective:To explore the anti-inflammatory and antioxidant effects of caraway on atopic dermatitis(AD)in mice.Methods:AD was induced in two stages,including sensitization and challenge with the application of 2,4 dinitrochlorobenzene 2% and 0.2%,respectively.Clinical symptoms and histological analysis of the skin were assessed.The effects of caraway on oxidant/antioxidant parameters as well as Th1-and Th2-related cytokines were also evaluated.Results:Caraway reduced the severity of dermatitis in AD-induced mice,as evidenced by significant inhibition of Th2-related cytokines(IL-4 and IL-13)and increased Th1-related cytokine(IFN-γ).Additionally,treatment with caraway significantly increased superoxide dismutase and catalase activity and decreased the malondialdehyde level in the serum of AD mice.Furthermore,caraway inhibited the differentiation of Th2 cells while favoring Th1 cell differentiation in the spleen via regulating their master transcription factors GATA3 and T-bet.Conclusions:Caraway could improve AD autoimmune responses and could be considered a potential candidate to treat AD disease.
