MET(Model Evaluation Tools)是美国国家大气研究中心(National Center for Atmospheric Research,NCAR)数值预报发展试验中心(Developmental Testbed Center,DTC)最新研发的数值预报检验、评估系统,其主要目的不仅在于为模式开发人员...MET(Model Evaluation Tools)是美国国家大气研究中心(National Center for Atmospheric Research,NCAR)数值预报发展试验中心(Developmental Testbed Center,DTC)最新研发的数值预报检验、评估系统,其主要目的不仅在于为模式开发人员提供模式性能的测试工具,而且方便最终用户通过MET来判别模式的预报能力,进而获得预报相应的预报指标。MET系统提供了丰富的站点、格点数据接口程序,它的核心组件集成了模式经典方法评估检验,高分辨率模式诊断分析,集合预报、概率预报、台风路径等多种最先进的模式检验评估算法。为了方便用户使用,MET系统还提供基于R语言的多种绘图脚本。在对MET系统简要阐述的基础上,给出了基于MET系统的面向对象或基于目标的MODE(Method for Object-Based Diagnostic Evaluation)方法、邻域法的具体降水检验个例,为使用MET系统进行模式检验、评估提供参考。展开更多
Spinal cord injury (SCI) is a severe complication of acute spinal injury, it can lead to axonal degeneration and necrosis of neurons, causing damage cross section below the movement, then loss of sensory, reflex and a...Spinal cord injury (SCI) is a severe complication of acute spinal injury, it can lead to axonal degeneration and necrosis of neurons, causing damage cross section below the movement, then loss of sensory, reflex and autonomous control function below the damage section. Nowadays, there is increasing evidence that transplantation of neural stem cells can help to repair spinal cord injury after spinal cord injury. The aim of this study was to research the function of miR-31 expression in differentiation of neural stem cells. Mir-31 was transfected the mimics and inhibitor into neural stem cells. By the morphological observation, the cell over expression of miR-31 was closer to NSCs. With the RT-PCR, Hb9 and STMN1 were up-regulate when miR-31 was inhibited, and Nestin was down-regulate. When miR-31 was over expression, the expression of Nestin and Hb9 was up-regulate. These findings suggest that miR-31 may play a significant role in proliferation and differentiation of neural stem cell and are potential targets for therapeutic interventions following spinal cord injury.展开更多
探索了磁诱导对脑卒中患者运动康复的影响,设计了磁场诱导大脑自发脑电的实验方法,通过极低频(16 Hz)、低强度(20 m T)脉冲磁场作用于8位脑卒中患者的患侧脑区,同时采集静息状态下的脑电信号并对数据进行分析,利用Jebsen-Taylor手功能测...探索了磁诱导对脑卒中患者运动康复的影响,设计了磁场诱导大脑自发脑电的实验方法,通过极低频(16 Hz)、低强度(20 m T)脉冲磁场作用于8位脑卒中患者的患侧脑区,同时采集静息状态下的脑电信号并对数据进行分析,利用Jebsen-Taylor手功能测试(JTT)和结合简化Fugl-Meyer运动功能评定量表和改良的Barthel指数评定量表评定康复效果。实验结果显示,磁诱导后量表评分显著升高,脑电高频段能量在运动皮层处有所增加。研究表明,磁诱导技术对脑卒中病人的康复有积极影响,可与传统康复疗法相结合在神经康复中起到辅助作用。展开更多
文摘MET(Model Evaluation Tools)是美国国家大气研究中心(National Center for Atmospheric Research,NCAR)数值预报发展试验中心(Developmental Testbed Center,DTC)最新研发的数值预报检验、评估系统,其主要目的不仅在于为模式开发人员提供模式性能的测试工具,而且方便最终用户通过MET来判别模式的预报能力,进而获得预报相应的预报指标。MET系统提供了丰富的站点、格点数据接口程序,它的核心组件集成了模式经典方法评估检验,高分辨率模式诊断分析,集合预报、概率预报、台风路径等多种最先进的模式检验评估算法。为了方便用户使用,MET系统还提供基于R语言的多种绘图脚本。在对MET系统简要阐述的基础上,给出了基于MET系统的面向对象或基于目标的MODE(Method for Object-Based Diagnostic Evaluation)方法、邻域法的具体降水检验个例,为使用MET系统进行模式检验、评估提供参考。
文摘Spinal cord injury (SCI) is a severe complication of acute spinal injury, it can lead to axonal degeneration and necrosis of neurons, causing damage cross section below the movement, then loss of sensory, reflex and autonomous control function below the damage section. Nowadays, there is increasing evidence that transplantation of neural stem cells can help to repair spinal cord injury after spinal cord injury. The aim of this study was to research the function of miR-31 expression in differentiation of neural stem cells. Mir-31 was transfected the mimics and inhibitor into neural stem cells. By the morphological observation, the cell over expression of miR-31 was closer to NSCs. With the RT-PCR, Hb9 and STMN1 were up-regulate when miR-31 was inhibited, and Nestin was down-regulate. When miR-31 was over expression, the expression of Nestin and Hb9 was up-regulate. These findings suggest that miR-31 may play a significant role in proliferation and differentiation of neural stem cell and are potential targets for therapeutic interventions following spinal cord injury.
文摘探索了磁诱导对脑卒中患者运动康复的影响,设计了磁场诱导大脑自发脑电的实验方法,通过极低频(16 Hz)、低强度(20 m T)脉冲磁场作用于8位脑卒中患者的患侧脑区,同时采集静息状态下的脑电信号并对数据进行分析,利用Jebsen-Taylor手功能测试(JTT)和结合简化Fugl-Meyer运动功能评定量表和改良的Barthel指数评定量表评定康复效果。实验结果显示,磁诱导后量表评分显著升高,脑电高频段能量在运动皮层处有所增加。研究表明,磁诱导技术对脑卒中病人的康复有积极影响,可与传统康复疗法相结合在神经康复中起到辅助作用。
