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Esophageal Cancer Patients with Less Lymph Node Dissection May Have Better Prognosis
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作者 Hannan Wang Yong Jia +2 位作者 chengxue dang Kun Zhu Kang Li 《Journal of Biosciences and Medicines》 2016年第7期45-52,共9页
Background: China is a high incidence area of esophageal cancer. Esophageal squamous cell carcinoma recurrence and mortality rates are relatively high. Recent studies show that the recurrence rate remains very high ev... Background: China is a high incidence area of esophageal cancer. Esophageal squamous cell carcinoma recurrence and mortality rates are relatively high. Recent studies show that the recurrence rate remains very high even through the implementation of lymph node expanding dissection. Methods and Results: In order to study the relationship between lymph node dissection number and survival of the patients with esophageal squamous cell carcinoma, 407 cases of esophageal cancer are selected in the First Affiliated Hospital of Xi’an Jiaotong University from January 2009 to June 2013. There were 15 cases without surgery, while the rest of the 392 patients were post-operation in follow-up. 54 patients were lost in follow-up, and the rate was 13.8%. Finally, there were 338 patients entered into our research. The median age was 58 (37 - 81), males accounted for 79%. The number of lymph node dissection is for a total of 2091, and a median of 5. Positive lymph nodes are 400, while the total positive rate is 19.1%. Conclusion: The number of lymph node dissection is divided into 3 groups that are 0 to 6, 7 to 11, 12 or more into three grades, and reduced number of lymph node dissection may prolong the survival (P < 0.05). The number of lymph node dissection should be as less as possible unless there is definitely positive lymph node metastasis. 展开更多
关键词 Esophageal Resection LYMPHADENECTOMY Survival Analysis
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从跟跑并跑到领跑:再论中国腹膜肿瘤学的建设发展与国际化历程
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作者 李雁 朱正纲 +9 位作者 崔书中 梁寒 王辉 蔡国响 许洪斌 彭正 党诚学 武爱文 杨盈赤 杨智冉(翻译) 《中国肿瘤临床》 CAS CSCD 北大核心 2022年第24期1256-1262,共7页
腹膜癌是癌症治疗历史上遗留的“老大难”问题,近40年来国际上致力于腹膜癌诊断治疗研究,取得了突破性进展,尤其是肿瘤细胞减灭术(cytoreductive surgery,CRS)加腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)体系... 腹膜癌是癌症治疗历史上遗留的“老大难”问题,近40年来国际上致力于腹膜癌诊断治疗研究,取得了突破性进展,尤其是肿瘤细胞减灭术(cytoreductive surgery,CRS)加腹腔热灌注化疗(hyperthermic intraperitoneal chemotherapy,HIPEC)体系的形成和优化。近20年来,中国的腹膜癌研究进步迅速,在仪器设备研发、技术方案优化、人才队伍培养、学科组织建设等方面,均取得令人瞩目的成就,并快速融入腹膜肿瘤学国际联盟的国际化发展大格局。中国胃癌腹膜转移癌临床研究成果成为国际里程碑事件,C-HIPEC方案的推广实施,2021年国内主办第12届国际腹膜癌大会,都是该领域的突出成果,也使中国在腹膜癌诊治方面实现了从跟跑并跑到领跑的历史性转变。但是,与中国腹膜癌患者的巨大治疗需求相比,腹膜肿瘤学发展事业仍然任重而道远,需要全国肿瘤学家加倍努力,推动立足于国情的中国腹膜癌防治研究走向新高度。 展开更多
关键词 腹膜癌 肿瘤细胞减灭术 腹腔热灌注化疗 发展
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Factors Affecting the Duration between Symptom Onset and Diagnosis in Patients with Gastric Cancer
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作者 Jianhao Yin Yong Zhang +5 位作者 Jianguo Lai Yao Tang Lei Meng Gang Xu Haonan Wang chengxue dang 《Journal of Biosciences and Medicines》 2016年第9期42-53,共12页
Background: The prognosis of patients with tumors is partly influenced by the stage when patients are diagnosed. Therefore, the time of confirmed diagnosis after onset can be considered as a prognostic predictor. Alth... Background: The prognosis of patients with tumors is partly influenced by the stage when patients are diagnosed. Therefore, the time of confirmed diagnosis after onset can be considered as a prognostic predictor. Although a few of studies work on it, factors that influence the duration remain poorly understood in different areas. Methods: This retrospective study involved patients with gastric cancer. Participants completed questionnaires by either phone or face-to-face interviews. Results: Females are with a longer interval than males. Farms lived in rural area and with New Rural Cooperative Medical Scheme are associated with a longer time interval. Patients whose income is mainly from their spouses also have a longer interval. Abdominal pain seems to be associated with longer interval time, while vomiting leads to a shorter time interval. Taking medicine after symptoms appear is associated with longer time intervals, especially those take medicine nonstandardly and more than 2 weeks. Conclusions: The results demonstrate that the medical resource in rural area should still be enhanced;meanwhile taking medicine without doctor’s advice should be cut down. Additional efforts must be made to devise strategies to properly guide patients’ behavior. 展开更多
关键词 Gastric Cancer Early Diagnosis Diagnosis Delay Help-Seeking Behavior
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