Despite surgical improvements and pharmacological advances,management of late-stage gastric cancer patients,especially those with hepatic metastasis remains challenging[1–3].Although nationwide registry data from SEE...Despite surgical improvements and pharmacological advances,management of late-stage gastric cancer patients,especially those with hepatic metastasis remains challenging[1–3].Although nationwide registry data from SEER(Surveillance,Epidemiology,and End Results)[4]and the Nordic database[5]in Western countries have provided epidemiological information for patients with gastric cancer liver metastasis(GCLM),little is known about the detailed clinical characteristics.展开更多
A photochromic molecular rotor based on stiff-stilbene(SSB-FMR)was handily prepared through coupled reaction,and further self-assembled with cucurbit[8]uril(CB[8])to form a 2:2 quaternary supramolecu-lar complex(SSB-F...A photochromic molecular rotor based on stiff-stilbene(SSB-FMR)was handily prepared through coupled reaction,and further self-assembled with cucurbit[8]uril(CB[8])to form a 2:2 quaternary supramolecu-lar complex(SSB-FMR/CB[8]).Significantly,the intervention of CB[8]on SSB-FMR achieved dual functions that assembly-induced emission enhancement and assembly-induced improvement of photoisomerized performance(especially reversibility)of stiff-stilbene molecular photoswitch.The supramolecular strategy further facilitated the assembly as a photoresponsive fluorescence switch with outstanding fatigue resis-tance,which was expediently applied in high-security-level QR code anti-counterfeiting and controllable lysosome targeted imaging.The study unprecedentedly provides a supramolecular method for highly effi-ciently improving photoisomerized performance especially reversibility of molecular photoswitches based on stiff-stilbene,and is of vital significance for the construction of intelligent materials with excellent ca-pability.展开更多
In this paper, the existence and uniqueness of the global generalized solution and the global classical solution for the Cauchy problem of the singularly perturbed sixth order Boussinesq type equation are proved.
We consider the singularly perturbed sixth-order Boussinesq-type equation, which describes the bidirectional propagation of small amplitude and long capillary gravity waves on the surface of shallow water for bond num...We consider the singularly perturbed sixth-order Boussinesq-type equation, which describes the bidirectional propagation of small amplitude and long capillary gravity waves on the surface of shallow water for bond number (surface tension parameter) less than but very close to 1/3. The sufficient conditions of blow-up of solution to the Cauchy problem for this equation are given.展开更多
基金This work was supported by the National Natural Science Foundation of China(81972790)the Beijing Nova Program(Z181100006218011).
文摘Despite surgical improvements and pharmacological advances,management of late-stage gastric cancer patients,especially those with hepatic metastasis remains challenging[1–3].Although nationwide registry data from SEER(Surveillance,Epidemiology,and End Results)[4]and the Nordic database[5]in Western countries have provided epidemiological information for patients with gastric cancer liver metastasis(GCLM),little is known about the detailed clinical characteristics.
基金National Natural Science Foundation of China (No.21801063)Top-Notch Talents Program of Henan Agricultural University (No.30501049)+1 种基金Natural Science Foundation of Henan Province (No.232300420132)the Merit Funding for the Oversea Staff of Henan Province for financial support
文摘A photochromic molecular rotor based on stiff-stilbene(SSB-FMR)was handily prepared through coupled reaction,and further self-assembled with cucurbit[8]uril(CB[8])to form a 2:2 quaternary supramolecu-lar complex(SSB-FMR/CB[8]).Significantly,the intervention of CB[8]on SSB-FMR achieved dual functions that assembly-induced emission enhancement and assembly-induced improvement of photoisomerized performance(especially reversibility)of stiff-stilbene molecular photoswitch.The supramolecular strategy further facilitated the assembly as a photoresponsive fluorescence switch with outstanding fatigue resis-tance,which was expediently applied in high-security-level QR code anti-counterfeiting and controllable lysosome targeted imaging.The study unprecedentedly provides a supramolecular method for highly effi-ciently improving photoisomerized performance especially reversibility of molecular photoswitches based on stiff-stilbene,and is of vital significance for the construction of intelligent materials with excellent ca-pability.
文摘In this paper, the existence and uniqueness of the global generalized solution and the global classical solution for the Cauchy problem of the singularly perturbed sixth order Boussinesq type equation are proved.
文摘We consider the singularly perturbed sixth-order Boussinesq-type equation, which describes the bidirectional propagation of small amplitude and long capillary gravity waves on the surface of shallow water for bond number (surface tension parameter) less than but very close to 1/3. The sufficient conditions of blow-up of solution to the Cauchy problem for this equation are given.