Bajiaolian, one of the species in the Mayapple family ( Podophyllum pelatum ), has been widely used as a traditional Chinese herbal medicine for the remedies of snake bites, general weakness, poisons, condyloma accumi...Bajiaolian, one of the species in the Mayapple family ( Podophyllum pelatum ), has been widely used as a traditional Chinese herbal medicine for the remedies of snake bites, general weakness, poisons, condyloma accuminata, lymphadenopathy, and certain tumors in China. In Western medicine, Podophyllum was first used medically as a laxative in the early 19th century. Since 1940, the resin of podophyllum has also been used topically for various skin lesions, such as warts and condyloma. Human poisonings have been reported.An animal model was established to investigate the neurotoxic effects of Bajiaolian. Podophyllotoxin, the major active ingredient in Podophyllum, was injected (ip) to young adult male rats at doses of 0, 5, 10, or 15 mg-kg-1 b.w.. The animals were sacrificed 72 h after injection.Neuronal changes were readily observable in animals treated with 10 or 15 mg-kg-1 of the toxin. Edematous changes of the anterior horn motoneurons were observed in the spinal cord. No neuronal necrosis was found. The type of neuronal swelling is believed to be only a transient change and would probably subside with time if no further assaults occur. More serious and perhaps longer term of changes were found in the dorsal ganglion neurons and the nerve fibers (axons) in the central and peripheral nervous system. Severe depletion of the Nissl substance (RNA/polyribosomes) was observed in the dorsal root ganglion neurons. Alterations in these sensory neurons would give rise to and correlate with the sensory disturbances experienced by the patients. Bodian staining also revealed a dose-related increase in the coarseness (thickness) of the nerve fibers (axons) in the cerebellum, cerebral cortex, brainstem, and spinal cord.This is the first scientific study showing the neurotoxicity of Bajiaolian, a commonly used Chinese herbal medicine. Toxicities on other organ systems by this drug certainly exist. Caution should be exercised in the dispensing and usage of this medicine.展开更多
Young male rats were orally intubated with podophyllotoxin: Group I, control animals, orally fed with vehicle only; Group Ⅱ, fed with an initial dose of 5 mg.kg-1 b.w., followed by a daily dose of 1.67 mg-kg-1 b.w. f...Young male rats were orally intubated with podophyllotoxin: Group I, control animals, orally fed with vehicle only; Group Ⅱ, fed with an initial dose of 5 mg.kg-1 b.w., followed by a daily dose of 1.67 mg-kg-1 b.w. for 7d. Group III, fed with an initial dose of 15 mg.kg-1 b.w., followed by a daily dose of 5 mg.kg-1 b.w. for 7d. All animals were sacrificed 72 h after the last dosing.Histopathological examination revealed dose-related fatty change of the liver, atrophy andi degenerative changes of the intestinal epithelial linings and testicular seminiferous tubules. Depletion of the pancreatic acinar cell granules was also apparent in the Group III animals. No pathology, however, was observed in the kidneys. The present study demonstrated for the first time degenerative changes in the liver, intestine, testis, and pancreas of animals ingested podophyllotoxin. These pathological changes correlate well with the clinical signs/symptoms of abnormal liver function, abdominal pain and diarrhea, and reduced serum amylase in humans poisonded by podophyllum. Inhibition of protein synthesis and mitosis (disruption of microtubules) are believed to be the underlying mechanisms of these changes observed in the animals intoxicated by. podophyllotoxin.展开更多
Microbridge testing is used to measure the Young's modulus and residual stresses of metallic films.Nickel film microbridges with widths of several hundred microns are fabricated by Microelectromechanical Systems.I...Microbridge testing is used to measure the Young's modulus and residual stresses of metallic films.Nickel film microbridges with widths of several hundred microns are fabricated by Microelectromechanical Systems.In order to measure the mechanical properties of nickel film microbridges,special shaft structure is designed to solve the problem of getting the load--deflection curves of metal film microbridge by Nanoin--denter XP system with normal Berkovich probe.Theoretical analysis of the micro--bridge load--deflection curve is proposed to evaluate the Young's modulus and residual stress of the films simultaneously.The calculated results based on the experimental measurements show that the average Young's modulus and residual stress are around 190GPa and 175MPa respectively,while the Young's modulus measured by Nano-hardness method on nickel film with silicon substrate is 186.8±7.34GPa.展开更多
A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 TeV.Even though the detecto...A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 TeV.Even though the detector construction is still underway,half of the KM2A array has been operating stably since the end of 2019.In this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray astronomy.We detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May 2020.With the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection power.The energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other experiments.This opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered.展开更多
Magnesium alloys,a novel functional material for the fabrication of fracturing tools,are being paid more and more attentions recently due to their relatively high mechanical properties and fast dissolubility ability a...Magnesium alloys,a novel functional material for the fabrication of fracturing tools,are being paid more and more attentions recently due to their relatively high mechanical properties and fast dissolubility ability after fracturing.In this study,the novel extruded Mg-10Gd-3Y-0.3Zr-xNi alloys will be reported and their microstructure,mechanical and corrosion behaviors will be also studied.The results show that Ni contents influence phase precipitation behaviors.With adding 0.2 wt%Ni,a large amount of Zr_(7)Ni_(10)phases will be precipitated insidesα-Mg matrix,directly leading to degradation of strength and large corrosion rate.With further increasing Ni contents,the precipitation phases can be changed from Mg_(5)RE to 18R-LPSO structure,resulting in higher mechanical properties and faster corrosion rate.Moreover,adding Ni element also change the texture orientation by influencing the precipitation behavior of the alloys.The alloys invented in this paper have attained the highest compressive and tensile properties among all the reported dissoluble magnesium alloys.This work is beneficial in understanding the role of Ni in the magnesium alloys and provides more materials alternatives for the fabrication of dissoluble fracturing tools.展开更多
The full array of the Large High Altitude Air Shower Observatory(LHAASO)has been in operation since July 2021.For its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energy...The full array of the Large High Altitude Air Shower Observatory(LHAASO)has been in operation since July 2021.For its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energyγ-rays using data collected from August 2021 to August 2022,resulting in an improvement in significance of the detection in the Crab Nebula of approximately 15%,compared with that of previous cuts.With the implementation of these new selection criteria,the angular resolution was also significantly improved by approximately 10%at tens of TeV.Other aspects of the full KM2A array performance,such as the pointing error,were also calibrated using the Crab Nebula.The resulting energy spectrum of the Crab Nebula in the energy range of 10-1000 TeV are well fitted by a log-parabola model,which is consistent with the previous results from LHAASO and other experiments.展开更多
The Large High Altitude Air Shower Observatory(LHAASO)has three sub-arrays,KM2A,WCDA,and WFCTA.The flux variations of cosmic ray air showers were studied by analyzing the KM2A data during a thunderstorm on June 10,202...The Large High Altitude Air Shower Observatory(LHAASO)has three sub-arrays,KM2A,WCDA,and WFCTA.The flux variations of cosmic ray air showers were studied by analyzing the KM2A data during a thunderstorm on June 10,2021.The number of shower events that meet the trigger conditions increases significantly in atmospheric electric fields,with a maximum fractional increase of 20%.The variations in trigger rates(increases or decreases)were found to be strongly dependent on the primary zenith angle.The flux of secondary particles increased significantly,following a trend similar to that of shower events.To better understand the observed behavior,Monte Carlo simulations were performed with CORSIKA and G4KM2A(a code based on GEANT4).We found that the experimental data(in saturated negative fields)were in good agreement with the simulations,assuming the presence of a uniform electric field of-700 V/cm with a thickness of 1500 m in the atmosphere above the observation level.Due to the acceleration/deceleration by the atmospheric electric field,the number of secondary particles with energy above the detector threshold was modified,resulting in the changes in shower detection rate.展开更多
The first Water Cherenkov detector of the LHAASO experiment(WCDA-1)has been operating since April 2019.The data for the first year have been analyzed to test its performance by observing the Crab Nebula as a standard ...The first Water Cherenkov detector of the LHAASO experiment(WCDA-1)has been operating since April 2019.The data for the first year have been analyzed to test its performance by observing the Crab Nebula as a standard candle.The WCDA-1 achieves a sensitivity of 65 mCU per year,with a statistical threshold of 5 cr.To accomplish this,a 97.7%cosmic-ray background rejection rate around 1 TeV and 99.8%around 6 TeV with an ap proximate photon acceptance of 50%is achieved after applying an algorithm to separate gamma-induced showers.The angular resolution is measured using the Crab Nebula as a point source to be approximately 0.45°at 1 TeV and better than 0.2°above 6 TeV,with a pointing accuracy better than 0.05°.These values all match the design specifications.The energy resolution is found to be 33%for gamma rays around 6 TeV.The spectral energy distribution of the Crab Nebula in the range from 500 GeV to 15.8 TeV is measured and found to be in agreement with the results from other TeV gamma ray observatories.展开更多
Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, ...Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, Al 2 O 3 content, microstructure, micro-hardness and wear resistance of coatings produced by arc spraying of the cored wires were experimentally investigated and were compared with those of pure aluminum coating.展开更多
Introduction One of main scientific goals of the Large High Altitude Air Shower Observatory(LHAASO)is to accurately measure the energy spectra of different cosmic ray compositions around the‘knee’region.The Wide Fiel...Introduction One of main scientific goals of the Large High Altitude Air Shower Observatory(LHAASO)is to accurately measure the energy spectra of different cosmic ray compositions around the‘knee’region.The Wide Field-of-View(FoV)Cherenkov Telescope Array(WFCTA),which is one of the main detectors of LHAASO and has 18 telescopes,is built to achieve this goal.Multiple telescopes are put together and point to connected directions for a larger FoV.Method Telescopes are deployed spatially as close as possible,but due to their own size,the distance between two adjacent telescopes is about 10 m.Therefore,the Cherenkov lateral distribution and the parallax between the two telescopes should be considered in the event building process for images crossing over the boundaries of FoVs of the telescopes.An event building method for Cherenkov images measured by multiple telescopes of WFCTA is developed.The performance of the shower measurements using the combined images is evaluated by comparing with showers that are fully contained by a virtual telescope in simulation.Results and conclusion It is proved that the developed event building process can help to increase the FoV of WFCTA by 30%while maintaining the same reconstruction quality,compared to the separate telescope reconstruction method.展开更多
The establishment of a possible connection between neutrino emission and gravitational-wave(GW)bursts is important to our understanding of the physical processes that occur when black holes or neutron stars merge.In t...The establishment of a possible connection between neutrino emission and gravitational-wave(GW)bursts is important to our understanding of the physical processes that occur when black holes or neutron stars merge.In the Daya Bay experiment,using the data collected from December 2011 to August 2017,a search was per-formed for electron-antineutrino signals that coincided with detected GW events,including GW150914,GW151012,GW151226,GW170104,GW170608,GW 170814,and GW 170817.We used three time windows of±10,±500,and±1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino candidates.The detected electron-antineutrino candidates were consistent with the expected background rates for all the three time windows.Assuming monochromatic spectra,we found upper limits(90%confidence level)of the electron-antineutrino fluence of(1.13-2.44)×10^(11)cm^(-2)at 5 MeV to 8.0×10^(7)cm^(-2)at 100 MeV for the three time w indows.Under the assumption of a Fermi-Dirac spectrum,the upper limits were found to be(5.4-7.0)×10^(9)cm^(2)for the three time windows.展开更多
The LHAASO-WFCTA experiment,which aims to observe cosmic rays in the sub-EeV range using the fluorescence technique,uses a new generation of high-performance telescopes.To ensure that the experiment has ex-cellent det...The LHAASO-WFCTA experiment,which aims to observe cosmic rays in the sub-EeV range using the fluorescence technique,uses a new generation of high-performance telescopes.To ensure that the experiment has ex-cellent detection capability associated with the measurement of the energy spectrum,the primary composition of cosmic rays,and so on,an accurate geometrical reconstruction of air-shower events is fundamental.This paper de-scribes the development and testing of geometrical reconstruction for stereo viewed events using the WFCTA(Wide Field of view Cherenkov/Fluorescence Telescope Array)detectors.Two approaches,which take full advantage ofthe WFCTA detectors.are investigated.One is the stereo-angular method,which uses the pointing of triggered SiPMs in the shower trajectory,and the other is the stereo-timing method,which uses the triggering time of the fired SiPMs.The results show that both methods have good geometrical resolution:the resolution of the stereo-timing method is slightly better than the stereo-angular method because the resolution of the latter is slightly limited by the shower track length.展开更多
The Water Cherenkov Detector Array(WCDA) is a major component of the Large High Altitude Air Shower Array Observatory(LHAASO), a new generation cosmic-ray experiment with unprecedented sensitivity, currently under con...The Water Cherenkov Detector Array(WCDA) is a major component of the Large High Altitude Air Shower Array Observatory(LHAASO), a new generation cosmic-ray experiment with unprecedented sensitivity, currently under construction. WCDA is aimed at the study of TeV γ-rays. In order to evaluate the prospects of searching for TeV γ-ray sources with WCDA, we present a projection of the one-year sensitivity of WCDA to TeV γ-ray sources from TeVCat using an all-sky approach. Out of 128 TeVCat sources observable by WCDA up to a zenith angle of 45°, we estimate that 42 would be detectable in one year of observations at a median energy of 1 TeV. Most of them are Galactic sources, and the extragalactic sources are Active Galactic Nuclei(AGN).展开更多
The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision era.The positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by ...The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision era.The positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya Bay experiment,in combination with the fission rates of fissile isotopes in the reactor,is used to extract the positron energy spectra resulting from the fission of specific isotopes.This information can be used to produce a precise,data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya Bay.The positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding method.Consistent results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and investigated.Given the reactor fission fractions,the technique can predict the energy spectrum to a 2%precision.In addition,we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.展开更多
Purpose The main scientific goal of LHAASO-WCDA is to survey gamma-ray sources with energy from 100 GeV to 30 TeV.To observe high-energy shower events,especially to measure the energy spectrum of cosmic rays from 100 ...Purpose The main scientific goal of LHAASO-WCDA is to survey gamma-ray sources with energy from 100 GeV to 30 TeV.To observe high-energy shower events,especially to measure the energy spectrum of cosmic rays from 100 TeV to 10 PeV,a dynamic range extension system(WCDA++)is designed to use a 1.5-inch PMT with a dynamic range of four orders of magnitude for each cell in WCDA-1.Method The dynamic range is extended by using these PMTs to measure the effective charge density in the core region of air shower events,which is an important parameter for identifying the composition of primary particles.Result and Conclusion The system has been running for more than one year.In this paper,the details of the design and performance of WCDA++are presented.展开更多
Purpose Observation of high energy and very high emission from Gamma Ray Bursts(GRBs)is crucial to study the gigantic explosion and the underline processes.With a large field-of-view and almost full duty cycle,the Wat...Purpose Observation of high energy and very high emission from Gamma Ray Bursts(GRBs)is crucial to study the gigantic explosion and the underline processes.With a large field-of-view and almost full duty cycle,the Water Cherenkov Detector Array(WCDA),a sub-array of the Large High Altitude Air Shower Observatory(LHAASO),is appropriate to monitor the very high energy emission from unpredictable transients such as GRBs.Method Nevertheless,the main issue for an extensive air shower array is the high energy threshold which limits the horizon of the detector.To address this issue a new trigger method is developed in this article to lower the energy threshold of WCDA for GRB observation.Result The proposed method significantly improves the detection efficiency of WCDA for gamma-rays around the GRB direction at 10-300 GeV.The sensitivity of the WCDA for GRB detection with the new trigger method is estimated.The achieved sensitivity of the quarter WCDA array above 10 GeV is comparable with that of Fermi-LAT.The data analysis process and corresponding fluence upper limit for GRB 190719C is presented as an example.展开更多
Using a(3+1)-D hydrodynamic model,CLVisc,we study the directed flow(vi)of light hadrons pro-duced in Au+Au,Ru+Ru,and Zr+Zr collisions at √SNN=200 GeV.The evolution of tilted energy density,pres-sure gradient,and radi...Using a(3+1)-D hydrodynamic model,CLVisc,we study the directed flow(vi)of light hadrons pro-duced in Au+Au,Ru+Ru,and Zr+Zr collisions at √SNN=200 GeV.The evolution of tilted energy density,pres-sure gradient,and radial flow along the x-direction is systematically investigated.The counter-clockwise tilt of the initial fireball is shown to be a vital source of directed flow for final light hadrons.A good description of directed flow is provided for light hadrons in central and mid-central Au+Au and isobar collisions at the RHIC.Our numeric-al results show a clear system size dependence for light hadron Vi across different collision systems.We further study the effect of nuclear structure on the directed flow and find that v1 for light hadrons is insensitive to nuclei with quadrupole deformation.展开更多
文摘Bajiaolian, one of the species in the Mayapple family ( Podophyllum pelatum ), has been widely used as a traditional Chinese herbal medicine for the remedies of snake bites, general weakness, poisons, condyloma accuminata, lymphadenopathy, and certain tumors in China. In Western medicine, Podophyllum was first used medically as a laxative in the early 19th century. Since 1940, the resin of podophyllum has also been used topically for various skin lesions, such as warts and condyloma. Human poisonings have been reported.An animal model was established to investigate the neurotoxic effects of Bajiaolian. Podophyllotoxin, the major active ingredient in Podophyllum, was injected (ip) to young adult male rats at doses of 0, 5, 10, or 15 mg-kg-1 b.w.. The animals were sacrificed 72 h after injection.Neuronal changes were readily observable in animals treated with 10 or 15 mg-kg-1 of the toxin. Edematous changes of the anterior horn motoneurons were observed in the spinal cord. No neuronal necrosis was found. The type of neuronal swelling is believed to be only a transient change and would probably subside with time if no further assaults occur. More serious and perhaps longer term of changes were found in the dorsal ganglion neurons and the nerve fibers (axons) in the central and peripheral nervous system. Severe depletion of the Nissl substance (RNA/polyribosomes) was observed in the dorsal root ganglion neurons. Alterations in these sensory neurons would give rise to and correlate with the sensory disturbances experienced by the patients. Bodian staining also revealed a dose-related increase in the coarseness (thickness) of the nerve fibers (axons) in the cerebellum, cerebral cortex, brainstem, and spinal cord.This is the first scientific study showing the neurotoxicity of Bajiaolian, a commonly used Chinese herbal medicine. Toxicities on other organ systems by this drug certainly exist. Caution should be exercised in the dispensing and usage of this medicine.
文摘Young male rats were orally intubated with podophyllotoxin: Group I, control animals, orally fed with vehicle only; Group Ⅱ, fed with an initial dose of 5 mg.kg-1 b.w., followed by a daily dose of 1.67 mg-kg-1 b.w. for 7d. Group III, fed with an initial dose of 15 mg.kg-1 b.w., followed by a daily dose of 5 mg.kg-1 b.w. for 7d. All animals were sacrificed 72 h after the last dosing.Histopathological examination revealed dose-related fatty change of the liver, atrophy andi degenerative changes of the intestinal epithelial linings and testicular seminiferous tubules. Depletion of the pancreatic acinar cell granules was also apparent in the Group III animals. No pathology, however, was observed in the kidneys. The present study demonstrated for the first time degenerative changes in the liver, intestine, testis, and pancreas of animals ingested podophyllotoxin. These pathological changes correlate well with the clinical signs/symptoms of abnormal liver function, abdominal pain and diarrhea, and reduced serum amylase in humans poisonded by podophyllum. Inhibition of protein synthesis and mitosis (disruption of microtubules) are believed to be the underlying mechanisms of these changes observed in the animals intoxicated by. podophyllotoxin.
基金This work was supported by the National Key Fundamental Research and Development Program(No.G1999033103),The measurements were conducted at the State Key Laboratory of Nonlinear Mechanics(LNM),Institute of Mechanics,Chinese Academy of Sciences.
文摘Microbridge testing is used to measure the Young's modulus and residual stresses of metallic films.Nickel film microbridges with widths of several hundred microns are fabricated by Microelectromechanical Systems.In order to measure the mechanical properties of nickel film microbridges,special shaft structure is designed to solve the problem of getting the load--deflection curves of metal film microbridge by Nanoin--denter XP system with normal Berkovich probe.Theoretical analysis of the micro--bridge load--deflection curve is proposed to evaluate the Young's modulus and residual stress of the films simultaneously.The calculated results based on the experimental measurements show that the average Young's modulus and residual stress are around 190GPa and 175MPa respectively,while the Young's modulus measured by Nano-hardness method on nickel film with silicon substrate is 186.8±7.34GPa.
基金Supported in China by National Key R&D program of China under the grants(2018YF A0404201.2018YFA0404202.2018YF A0404203)by NSFC(12022502,190527,135011,11761141001.U1931112,11775131,U1931201,11905043,U1931108)by NSFSPC(ZR2019MA014),and in Thailand by RTA6280002 from Thailand Science Research and Innovation。
文摘A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 TeV.Even though the detector construction is still underway,half of the KM2A array has been operating stably since the end of 2019.In this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray astronomy.We detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May 2020.With the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection power.The energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other experiments.This opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered.
基金The National Natural Science Foundation of China(Nos.51671017,51971020)the Major State Research and Development Program of China(No.2016YFB0300801)+4 种基金Beijing Municipal Natural Science Foundation(No.2202033)Beijing Laboratory of Metallic Materials and Processing for Modern Transportationthe fund of the State Key Laboratory of Solidification Processing in NWPU(No.SKLSP201835)the Fundamental Research Funds for the Central Universities(No.FRF-IC-19–010,FRF-IC-19–015)the Opening Research Fund of State Key Laboratory for Advanced Metals and Materials(2018-Z04)。
文摘Magnesium alloys,a novel functional material for the fabrication of fracturing tools,are being paid more and more attentions recently due to their relatively high mechanical properties and fast dissolubility ability after fracturing.In this study,the novel extruded Mg-10Gd-3Y-0.3Zr-xNi alloys will be reported and their microstructure,mechanical and corrosion behaviors will be also studied.The results show that Ni contents influence phase precipitation behaviors.With adding 0.2 wt%Ni,a large amount of Zr_(7)Ni_(10)phases will be precipitated insidesα-Mg matrix,directly leading to degradation of strength and large corrosion rate.With further increasing Ni contents,the precipitation phases can be changed from Mg_(5)RE to 18R-LPSO structure,resulting in higher mechanical properties and faster corrosion rate.Moreover,adding Ni element also change the texture orientation by influencing the precipitation behavior of the alloys.The alloys invented in this paper have attained the highest compressive and tensile properties among all the reported dissoluble magnesium alloys.This work is beneficial in understanding the role of Ni in the magnesium alloys and provides more materials alternatives for the fabrication of dissoluble fracturing tools.
基金Supported by the National Key R&D Program of China(2018YFA0404201,2018YFA0404202,2018YFA0404203,2018YFA0404204)the National Natural Science Foundation of China(12022502,12205314,12105301,12261160362,12105294,U1931201)+2 种基金the Youth Innovation Promotion Association CAS(2022010)in Thailand by the National Science and Technology Development Agency(NSTDA)the National Research Council of Thailand(NRCT):High-Potential Research Team Grant Program(N42A650868)。
文摘The full array of the Large High Altitude Air Shower Observatory(LHAASO)has been in operation since July 2021.For its kilometer-square array(KM2A),we optimized the selection criteria for very high and ultrahigh energyγ-rays using data collected from August 2021 to August 2022,resulting in an improvement in significance of the detection in the Crab Nebula of approximately 15%,compared with that of previous cuts.With the implementation of these new selection criteria,the angular resolution was also significantly improved by approximately 10%at tens of TeV.Other aspects of the full KM2A array performance,such as the pointing error,were also calibrated using the Crab Nebula.The resulting energy spectrum of the Crab Nebula in the energy range of 10-1000 TeV are well fitted by a log-parabola model,which is consistent with the previous results from LHAASO and other experiments.
基金Supported in China by National Key R&D program of China(2018YFA0404201,2018YFA0404202,2018YFA0404203,2018YFA0404204)NSFC(U2031101,11475141,12147208)in Thailand by RTA6280002 from Thailand Science Research and Innovation。
文摘The Large High Altitude Air Shower Observatory(LHAASO)has three sub-arrays,KM2A,WCDA,and WFCTA.The flux variations of cosmic ray air showers were studied by analyzing the KM2A data during a thunderstorm on June 10,2021.The number of shower events that meet the trigger conditions increases significantly in atmospheric electric fields,with a maximum fractional increase of 20%.The variations in trigger rates(increases or decreases)were found to be strongly dependent on the primary zenith angle.The flux of secondary particles increased significantly,following a trend similar to that of shower events.To better understand the observed behavior,Monte Carlo simulations were performed with CORSIKA and G4KM2A(a code based on GEANT4).We found that the experimental data(in saturated negative fields)were in good agreement with the simulations,assuming the presence of a uniform electric field of-700 V/cm with a thickness of 1500 m in the atmosphere above the observation level.Due to the acceleration/deceleration by the atmospheric electric field,the number of secondary particles with energy above the detector threshold was modified,resulting in the changes in shower detection rate.
基金Supported by the following grants:the National Key R&D program of China(2018YFA0404201,2018YFA0404202,2018YFA0404203)the National Natural Science Foundation of China(12022502,11905227,U1931112,11635011,11761141001,Y811A35,11675187,U1831208,U1931111)in Thailand by RTA6280002 from Thailand Science Research and Innovation。
文摘The first Water Cherenkov detector of the LHAASO experiment(WCDA-1)has been operating since April 2019.The data for the first year have been analyzed to test its performance by observing the Crab Nebula as a standard candle.The WCDA-1 achieves a sensitivity of 65 mCU per year,with a statistical threshold of 5 cr.To accomplish this,a 97.7%cosmic-ray background rejection rate around 1 TeV and 99.8%around 6 TeV with an ap proximate photon acceptance of 50%is achieved after applying an algorithm to separate gamma-induced showers.The angular resolution is measured using the Crab Nebula as a point source to be approximately 0.45°at 1 TeV and better than 0.2°above 6 TeV,with a pointing accuracy better than 0.05°.These values all match the design specifications.The energy resolution is found to be 33%for gamma rays around 6 TeV.The spectral energy distribution of the Crab Nebula in the range from 500 GeV to 15.8 TeV is measured and found to be in agreement with the results from other TeV gamma ray observatories.
文摘Cored wires for electric arc spraying of Al/Al 2 O 3 MMC coatings were developed, with Al 2 O 3 powder as the core material and commercial aluminium strip as the retaining sheath. The bond strength, Al 2 O 3 content, microstructure, micro-hardness and wear resistance of coatings produced by arc spraying of the cored wires were experimentally investigated and were compared with those of pure aluminum coating.
基金supported by the National Key R&D program of China under grants 2018YFA0404201This research work is also supported by the National Natural Science Foundation of China,with NSFC Grants No.11635011,No.11761141001,No.11905240,No.12105293,No.12105294,No.U2031103,No.U1831208,No.11503021,No.11205126,No.11947404,and No.11675187+2 种基金by IHEP innovation project No.E25451U2by the Science and Technology Department of Sichuan Province 2021YFSY0031by the Xiejialin Foundation of IHEP No.E2546IU2,by RTA6280002 from Thailand Science Research and Innovation in Thailand.
文摘Introduction One of main scientific goals of the Large High Altitude Air Shower Observatory(LHAASO)is to accurately measure the energy spectra of different cosmic ray compositions around the‘knee’region.The Wide Field-of-View(FoV)Cherenkov Telescope Array(WFCTA),which is one of the main detectors of LHAASO and has 18 telescopes,is built to achieve this goal.Multiple telescopes are put together and point to connected directions for a larger FoV.Method Telescopes are deployed spatially as close as possible,but due to their own size,the distance between two adjacent telescopes is about 10 m.Therefore,the Cherenkov lateral distribution and the parallax between the two telescopes should be considered in the event building process for images crossing over the boundaries of FoVs of the telescopes.An event building method for Cherenkov images measured by multiple telescopes of WFCTA is developed.The performance of the shower measurements using the combined images is evaluated by comparing with showers that are fully contained by a virtual telescope in simulation.Results and conclusion It is proved that the developed event building process can help to increase the FoV of WFCTA by 30%while maintaining the same reconstruction quality,compared to the separate telescope reconstruction method.
基金Daya Bay is supported in part by the Ministry of Science and Technology o f China, the U.S. Department o f Energy, the Chinese Academy of Sciences, the CASCenter for Excellence in Particle Physics, the National Natural Science Foundation of China, the Guangdong provincial government, the Shenzhen municipal government,the China General Nuclear Power Group, Key Laboratory of Particle and Radiation Imaging (Tsinghua University), the Ministry of Education, Key Laboratory ofParticle Physics and Particle Irradiation (Shandong University), the Ministry o f Education, Shanghai Laboratory for Particle Physics and Cosmology, the ResearchGrants Council o f the Hong Kong Special Administrative Region of China, the University Development Fund of the University of Hong Kong, the MOE program forResearch of Excellence at National Taiwan University, National Chiao-Tung University, NSC fund support from Taiwan, the U.S. National Science Foundation, the AlfredP. Sloan Foundation, the Ministry o f Education, Youth, and Sports of the Czech Republic, the Charles University GAUK (284317), the Joint Institute o f NuclearResearch in Dubna, Russia, the National Commission of Scientific and Technological Research of Chile, and the Tsinghua University Initiative Scientific Research Program.
文摘The establishment of a possible connection between neutrino emission and gravitational-wave(GW)bursts is important to our understanding of the physical processes that occur when black holes or neutron stars merge.In the Daya Bay experiment,using the data collected from December 2011 to August 2017,a search was per-formed for electron-antineutrino signals that coincided with detected GW events,including GW150914,GW151012,GW151226,GW170104,GW170608,GW 170814,and GW 170817.We used three time windows of±10,±500,and±1000 s relative to the occurrence of the GW events and a neutrino energy range of 1.8 to 100 MeV to search for correlated neutrino candidates.The detected electron-antineutrino candidates were consistent with the expected background rates for all the three time windows.Assuming monochromatic spectra,we found upper limits(90%confidence level)of the electron-antineutrino fluence of(1.13-2.44)×10^(11)cm^(-2)at 5 MeV to 8.0×10^(7)cm^(-2)at 100 MeV for the three time w indows.Under the assumption of a Fermi-Dirac spectrum,the upper limits were found to be(5.4-7.0)×10^(9)cm^(2)for the three time windows.
基金National Natural Science Foundation of China(11903005,11563004,11475190)。
文摘The LHAASO-WFCTA experiment,which aims to observe cosmic rays in the sub-EeV range using the fluorescence technique,uses a new generation of high-performance telescopes.To ensure that the experiment has ex-cellent detection capability associated with the measurement of the energy spectrum,the primary composition of cosmic rays,and so on,an accurate geometrical reconstruction of air-shower events is fundamental.This paper de-scribes the development and testing of geometrical reconstruction for stereo viewed events using the WFCTA(Wide Field of view Cherenkov/Fluorescence Telescope Array)detectors.Two approaches,which take full advantage ofthe WFCTA detectors.are investigated.One is the stereo-angular method,which uses the pointing of triggered SiPMs in the shower trajectory,and the other is the stereo-timing method,which uses the triggering time of the fired SiPMs.The results show that both methods have good geometrical resolution:the resolution of the stereo-timing method is slightly better than the stereo-angular method because the resolution of the latter is slightly limited by the shower track length.
基金Supported by National Natural Science Foundation of China(11761141001,11635011,11873005)The LHAASO project is supported by the National Key R&D Program of China(2018YFA0404200),the Chinese Academy of Sciences,the Key Laboratory of Particle Astrophysics,IHEP,CAS。
文摘The Water Cherenkov Detector Array(WCDA) is a major component of the Large High Altitude Air Shower Array Observatory(LHAASO), a new generation cosmic-ray experiment with unprecedented sensitivity, currently under construction. WCDA is aimed at the study of TeV γ-rays. In order to evaluate the prospects of searching for TeV γ-ray sources with WCDA, we present a projection of the one-year sensitivity of WCDA to TeV γ-ray sources from TeVCat using an all-sky approach. Out of 128 TeVCat sources observable by WCDA up to a zenith angle of 45°, we estimate that 42 would be detectable in one year of observations at a median energy of 1 TeV. Most of them are Galactic sources, and the extragalactic sources are Active Galactic Nuclei(AGN).
基金Supported in part by the Ministry of Science and Technology of Chinathe U.S.Department of Energy,the Chinese Academy of Sciences,the CAS Center for Excellence in Particle Physics,the National Natural Science Foundation of China+3 种基金the Guangdong provincial governmentthe Shenzhen municipal government,the China General Nuclear Power Group,the Research Grants Council of the Hong Kong Special Administrative Region of China,the Ministry of Education in TWthe U.S.National Science Foundation,the Ministry of Education,Youth,and Sports of the Czech Republic,the Charles University Research Centre UNCE,the Joint Institute of Nuclear Research in Dubna,Russiathe National Commission of Scientific and Technological Research of Chile。
文摘The prediction of reactor antineutrino spectra will play a crucial role as reactor experiments enter the precision era.The positron energy spectrum of 3.5 million antineutrino inverse beta decay reactions observed by the Daya Bay experiment,in combination with the fission rates of fissile isotopes in the reactor,is used to extract the positron energy spectra resulting from the fission of specific isotopes.This information can be used to produce a precise,data-based prediction of the antineutrino energy spectrum in other reactor antineutrino experiments with different fission fractions than Daya Bay.The positron energy spectra are unfolded to obtain the antineutrino energy spectra by removing the contribution from detector response with the Wiener-SVD unfolding method.Consistent results are obtained with other unfolding methods.A technique to construct a data-based prediction of the reactor antineutrino energy spectrum is proposed and investigated.Given the reactor fission fractions,the technique can predict the energy spectrum to a 2%precision.In addition,we illustrate how to perform a rigorous comparison between the unfolded antineutrino spectrum and a theoretical model prediction that avoids the input model bias of the unfolding method.
基金This research work is also supported by following grants.The National Key R&D program of China under the Grant 2018YFA0404201,2018YFA0404202 and 2018YFA0404203by the National Natural Science Foundation of China(NSFC Grants Nos.12022502,No.11905227,No.U1931112,No.11635011,No.11761141001,No.Y811A35,No.11675187,No.U1831208,No.11873005)+1 种基金by the Key R&D Program of SiChuan Province under the Grant 2019ZYZF0001in Thailand by RTA6280002 from Thailand Science Research and Innovation.
文摘Purpose The main scientific goal of LHAASO-WCDA is to survey gamma-ray sources with energy from 100 GeV to 30 TeV.To observe high-energy shower events,especially to measure the energy spectrum of cosmic rays from 100 TeV to 10 PeV,a dynamic range extension system(WCDA++)is designed to use a 1.5-inch PMT with a dynamic range of four orders of magnitude for each cell in WCDA-1.Method The dynamic range is extended by using these PMTs to measure the effective charge density in the core region of air shower events,which is an important parameter for identifying the composition of primary particles.Result and Conclusion The system has been running for more than one year.In this paper,the details of the design and performance of WCDA++are presented.
基金This work is supported by the National Key R&D Program of China under the Grant 2018YFA0404201the Natural Sciences Foundation of China under the Grants 12022502,11635011the Key R&D Program of SiChuan Province under the Grant 2019ZYZF0001.
文摘Purpose Observation of high energy and very high emission from Gamma Ray Bursts(GRBs)is crucial to study the gigantic explosion and the underline processes.With a large field-of-view and almost full duty cycle,the Water Cherenkov Detector Array(WCDA),a sub-array of the Large High Altitude Air Shower Observatory(LHAASO),is appropriate to monitor the very high energy emission from unpredictable transients such as GRBs.Method Nevertheless,the main issue for an extensive air shower array is the high energy threshold which limits the horizon of the detector.To address this issue a new trigger method is developed in this article to lower the energy threshold of WCDA for GRB observation.Result The proposed method significantly improves the detection efficiency of WCDA for gamma-rays around the GRB direction at 10-300 GeV.The sensitivity of the WCDA for GRB detection with the new trigger method is estimated.The achieved sensitivity of the quarter WCDA array above 10 GeV is comparable with that of Fermi-LAT.The data analysis process and corresponding fluence upper limit for GRB 190719C is presented as an example.
基金Supported by the National Natural Science Foundation of China(NSFC)(11935007)Guangdong Major Project of Basic and Applied Basic Research(2020B0301030008)+2 种基金the Natural Science Foundation of Hubei Province(2021CFB272),the Education Department of Hubei Province of China with Young Talents Project(Q20212703)the Open Foundation of Key Laboratory of Quark and Lepton Physics(MOE)(QLPL202104)the Xiaogan Natural Science Foundation(XGKJ2021010016)。
文摘Using a(3+1)-D hydrodynamic model,CLVisc,we study the directed flow(vi)of light hadrons pro-duced in Au+Au,Ru+Ru,and Zr+Zr collisions at √SNN=200 GeV.The evolution of tilted energy density,pres-sure gradient,and radial flow along the x-direction is systematically investigated.The counter-clockwise tilt of the initial fireball is shown to be a vital source of directed flow for final light hadrons.A good description of directed flow is provided for light hadrons in central and mid-central Au+Au and isobar collisions at the RHIC.Our numeric-al results show a clear system size dependence for light hadron Vi across different collision systems.We further study the effect of nuclear structure on the directed flow and find that v1 for light hadrons is insensitive to nuclei with quadrupole deformation.