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外圆磨削加工的仿真、优化及控制 被引量:12
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作者 S.Malkin c.guo 张一飞 《金刚石与磨料磨具工程》 CAS 2001年第5期11-16,共6页
磨削技术已广泛应用于最后加工有光滑表面和高精度要求的零件。在过去的 30年里 ,经过广泛的研究 ,对磨削加工的许多方面有了一个较为清楚的了解。本论文的目的在于说明怎样利用我们对磨削过程的理解来预报磨削特性和获得最佳加工条件... 磨削技术已广泛应用于最后加工有光滑表面和高精度要求的零件。在过去的 30年里 ,经过广泛的研究 ,对磨削加工的许多方面有了一个较为清楚的了解。本论文的目的在于说明怎样利用我们对磨削过程的理解来预报磨削特性和获得最佳加工条件。一个集成了描述磨削过程中不同方面的分析模块的软件包已被开发出来。这软件包括三个主要模块 :仿真、校准和优化。仿真模块作为一个虚拟磨床来预测磨削过程和零件质量。校准模块通过实测参数如功率、表面粗糙度和椭圆度等对模型的系数进行修正 ,从而对实际磨削特性进行学习。优化模块是以最小化周期时间或以基于服从工件质量约束校正模型后的周期时间为目标来确定磨削和修整参数。本软件已被集成进了PC开放体系控制器 (OAC) ,作为智能磨削系统 (IGS)的基础。 展开更多
关键词 建模 控制 外圆磨削 仿真 优化
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CATHODIC PROCESS AND WEAR RESISTANCE OF ELECTRO-DEPOSITED RE-Ni-W-P-SiC COMPOSITE COATING 被引量:16
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作者 Z.c.guo,X.Y.Zhu,R.D.Xu and X.W.YangFaculty of Material and Metallurgy Engineering, Kunming University of Science and Technology, Kunming650093, chinaManuscript received 26 December 2001 in revised form 23 April 2002 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2002年第4期369-374,共6页
Cathodic deposition current density of the composite coatings increases when SiC par-ticles and rare earth (RE) were added in the bath, which is profitable for Ni- W-P alloy to deposit in the cathod, forming Ni-W-P-Si... Cathodic deposition current density of the composite coatings increases when SiC par-ticles and rare earth (RE) were added in the bath, which is profitable for Ni- W-P alloy to deposit in the cathod, forming Ni-W-P-SiC and RE-Ni-W-P-SiC composite coatings. On the contrary, the addition of PTFE in the bath decreases cathodic deposition current density of the coatings. The current density increases a little when the amount of RE is 7-9g/l; however, the current density increases greatly when the amount of RE is increased to 11-13g/l. Bui ij the amount of RE is raised further, the current density decreases. Hardness and wear resistance of RE-Ni-W-P-SiC composite coating have been studied, and the results show that the hardness and wear resistance of RE-Ni-W-P-SiC composite coating increase with increasing heat treatment tempera-ture, which reach peak values at 400℃; while the hardness and wear resistance of the coating decrease with the rise of heat treated temperature continuously. 展开更多
关键词 ELECTRODEPOSITION RE-Ni-W-P-SiC composite coating cathodic process hardness and wear resistance
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Acquired sensorineural hearing loss,oxidative stress,and microRNAs
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作者 Desmond A.Nunez Ru c.guo 《Neural Regeneration Research》 SCIE CAS 2025年第9期2513-2519,共7页
Hearing loss is the third leading cause of human disability.Age-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health burden.Noise-induced,ototox... Hearing loss is the third leading cause of human disability.Age-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health burden.Noise-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing loss.The etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental factors.Oxidative stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing loss.Short non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic response.Sensory hair cell death is a central histopathological finding in sensorineural hearing loss.As these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing loss.Ovid EMBASE,Ovid MEDLINE,Web of Science Core Collection,and ClinicalTrials.gov databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical trials.Registe red clinical trials known to the senior author we re also assessed.A total of 222studies were thus identified.After excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text screening.This resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative review.MiRNAs miR-34a and miR-29b levels increase with age in mice.These miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P GC-1α),SIRT1p53,and SIRT1/hypoxia-inducible factor 1-alpha 展开更多
关键词 hearing loss HYPOXIA MICRORNAS oxidative stress SENSORINEURAL
The development of ^(222)Rn detectors for JUNO prototype
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作者 Y.P.Zhang J.c.Liu +5 位作者 c.guo Y.B.Huang c.Xu M.Y.Guan c.G.Yang P.Zhang 《Radiation Detection Technology and Methods》 2018年第1期32-37,共6页
Background JUNO(The Jiangmen Underground Neutrino Observatory)is a multipurpose neutrino experiment,and it has very strict requirements for the detector.According to the MC simulation for JUNO experiment requirements,... Background JUNO(The Jiangmen Underground Neutrino Observatory)is a multipurpose neutrino experiment,and it has very strict requirements for the detector.According to the MC simulation for JUNO experiment requirements,the Rn concentration in the water of the veto detector should be less than 0.2Bq/m^(3).In order to measure such low Rn concentration,two kinds of high-sensitivity Rn measurement systems have been developed.Method Based on the water system of JUNO prototype,two kinds of high-sensitivity Rn detectors have been developed,namely the Si-PIN Rn detector and the LS Rn detector.The Si-PIN Rn detector uses a Si-PIN photodiode to detect theαfrom ^(214)Po decay and the LS Rn detector detects the coincident signals ofβfrom ^(214)Bi decay andβfrom ^(214)Po decay.Result The background measurement of Si-PIN Rn detector and LS Rn detector is performed to estimate the sensitivity.The sensitivity of Si-PIN Rn detector is around 9.0mBq/m^(3) and the sensitivity of LS Rn detector is around 64.0Bq/m^(3).Conclusion Both of the Si-PIN Rn detector and the LS Rn detector are working well with the JUNO prototype at present,and both of them can be developed as an online Rn concentration monitoring device for JUNO veto detector. 展开更多
关键词 RADON Si-PIN Liquid scintillator
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Study on the radon removal for the water system of Jiangmen Underground Neutrino Observatory
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作者 c.guo J.c.Liu +7 位作者 Y.P.Zhang P.Zhang c.G.Yang Y.B.Huang W.X.Xiong H.Q.Zhang Y.T.Wei Y.Y.Gan 《Radiation Detection Technology and Methods》 2018年第2期128-132,共5页
Background The Jiangmen Underground Neutrino Observatory(JUNO),a 20-kton multipurpose underground liquid scintillator detector,was proposed with the determination of the neutrino mass hierarchy as a primary physics go... Background The Jiangmen Underground Neutrino Observatory(JUNO),a 20-kton multipurpose underground liquid scintillator detector,was proposed with the determination of the neutrino mass hierarchy as a primary physics goal.To veto the cosmogenic background and shield the central detector from the environmental radioactivity,a multi-veto system,which consists of a water Cherenkov detector and a top tracker detector,is required.In order to keep the water quality good and remove the radon from water,an ultrapure water system,a radon removal system and radon concentration measurement system have been designed.Method The JUNO ultrapure water system was designed on the basis of the water system of the Daya Bay experiment.By installing the degassing membrane devices on the water system of JUNO prototype and Daya Bay experiment which can remove radon from water,the radon removal efficiency has been measured at the conditions of different gas–liquid phase pressures and different gas concentrations in water using the radon measurement system.Result Loading carbon dioxide into the water and increasing the inlet water pressure could help to improve the radon removal efficiency of the degassing membrane devices,and the radon concentration in water can be reduced to∼0.1 Bq/m^(3).Conclusion A reliable ultrapure water production and circulation system has been designed to keep the water quality good and to reduce the radon concentration in water for JUNO water Cherenkov detector.The radon concentration in water can satisfy the requirement of JUNO by using the Liqui-Cel degassing membrane devices. 展开更多
关键词 Ultra-pure water RADON Degassing membranes
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连续修整蠕动磨削的优化
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作者 cguo 林王产 +1 位作者 刘品潇 郑冬 《国外金属加工》 2004年第3期31-35,共5页
本文介绍基于磨削模型和在线功率测量,适当调整工件速度和横向进给,缩短加工生产周期和砂轮消耗,连续修整的蠕动磨削的优化。热流保持在烧损极限之下,以避免磨后表面的热损伤.磨削力控制在许用值之下,以避免叶片过量应变引起的表... 本文介绍基于磨削模型和在线功率测量,适当调整工件速度和横向进给,缩短加工生产周期和砂轮消耗,连续修整的蠕动磨削的优化。热流保持在烧损极限之下,以避免磨后表面的热损伤.磨削力控制在许用值之下,以避免叶片过量应变引起的表面裂纹。使用这种方法。维持热流和磨削力在它们许用临界值之下,可将磨削循环时间减少40%。 展开更多
关键词 镍合金 优化 蠕动磨削 成形磨削 在线功率测量
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STCF conceptual design report (Volume 1): Physics & detector 被引量:3
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作者 M.Achasov X.c.Ai +163 位作者 L.P.An R.Aliberti Q.An X.Z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko Z.H.Bu F.M.cai H.cai J.J.cao Q.H.cao X.cao Z.cao Q.chang K.T.chao D.Y.chen H.chen H.X.chen J.F.chen K.chen L.L.chen P.chen S.L.chen S.M.chen S.chen S.P.chen W.chen X.chen X.F.chen X.R.chen Y.chen Y.Q.chen H.Y.cheng J.cheng S.cheng T.G.cheng J.P.Dai L.Y.Dai X.c.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.Epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich c.Q.Feng X.Feng Y.T.Feng J.L.Fu J.Gao Y.N.Gao P.S.Ge c.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong B.Gou W.Gradl J.L.Gu A.Guevara L.c.Gui A.Q.guo F.K.guo J.c.guo J.guo Y.P.guo Z.H.guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.L.He Z.B.He Z.X.Heng B.L.Hou T.J.Hou Y.R.Hou c.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.c.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.B.Jiang J.Jiang S.Z.Jiang J.B.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang B.c.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.Lei E.Levichev c.H.Li c.Li D.Y.Li F.Li G.Li G.Li H.B.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X 《Frontiers of physics》 SCIE CSCD 2024年第1期1-154,共154页
The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of... The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics community.It is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or higher.The STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard Model.The STCF project in China is under development with an extensive R&D program.This document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies. 展开更多
关键词 electron–positron collider tau-charm region high luminosity STCF detector conceptual design
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A study of liquid argon detector’s n/discrimination capability with PMT or SiPM readout
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作者 Y.D.chen Y.Lei +6 位作者 L.Wang M.Y.Guan T.A.Wang c.guo J.c.Liu c.G.Yang X.H.Liang 《Radiation Detection Technology and Methods》 CSCD 2024年第2期1246-1253,共8页
Background Liquid Argon(LAr)is used as a target material in several current and planned experiments related to dark matter direct searching and neutrino detection.Argon provides excellent pulse shape discrimination(PS... Background Liquid Argon(LAr)is used as a target material in several current and planned experiments related to dark matter direct searching and neutrino detection.Argon provides excellent pulse shape discrimination(PSD)capability,which could separate the electron recoil backgrounds from the expected nuclear recoil signals.As the next-generation photosensors,silicon photon multiplier(SiPM)is expected to replace traditional photon multiplier tubes.Purpose The purpose of this paper is to compare the PSD capability of a LAr detector between using SiPMs as photosensors and using PMTs as photosensors.Methods The PSD capability of a LAr detector is determined through the prompt fraction method,which relies on the analysis of output pulses.These pulses are generated using Monte Carlo simulation,incorporating real single photoelectron pulses obtained from a PMT or a SiPM.Results Three kinds of SiPMs and one kind of PMT have been used to compare the PSD capability of a LAr detector.The use of J-60035 SiPM results in a better PSD capability compared to the use of PMT as a photosensor,while using the other two kinds of SiPM deteriorates the PSD capability.Conclusion SiPM is a promising photosensor candidate for a LAr detector.The better energy resolution could help to improve its PSD capability,while the higher probabilities of cross-talk and after-pulse degrade its PSD capability.Notably,after-pulse has a more significant impact compared to cross-talk because after-pulse influences the energy distribution within the time window,while cross-talk primarily affects the energy resolution of the detector. 展开更多
关键词 Liquid argon SIPM PMT F90 PSD
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On the mechanism of Si-promoted destabilization of TiC_(x)particles in Al alloys 被引量:1
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作者 H.Dong Y.c.guo +7 位作者 Y.Z.chen F.Xia Q.Q.guo Q.chen G.L.Li J.Y.Zhao Y.Zhong J.P.Li 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第34期17-26,共10页
TiC_(x)is an excellent composite strengthening particle and grain refiner for Al alloys.However,the stability of TiC_(x)is poor when solute Si exists in Al alloy melts,which significantly depresses its strengthening a... TiC_(x)is an excellent composite strengthening particle and grain refiner for Al alloys.However,the stability of TiC_(x)is poor when solute Si exists in Al alloy melts,which significantly depresses its strengthening and grain refining effects.In this work,the destabilization mechanisms of the TiC_(x)particles in Al-Si alloy melt with a composition of Al-7Si-7.5TiC were explored via experiments,first-principles calculations and thermodynamic calculations.The experimental results show that Si atoms diffuse into TiC_(x)and Ti atoms are released into the Al melt to form a Ti-rich transition zone during the insulation of TiC_(x)in Al-Si melt,and the TiAlySiz and Al_(4)C_(3)phases are solidified in the Ti-rich zone and at Ti-rich zone/TiC_(x)interface,respectively.The first principles calculations show that the low formation energy of C vacancies facilitates the rapid diffusion of Si atoms in TiC_(x),while the doping of Si atoms reduces the energy barrier of diffusion of Ti atoms in TiC_(x)and promotes the formation of Ti-rich zones.The thermodynamic calculations show that the wide crystallization temperature range of the destabilized product TiAlySiz phase is the key to continuous decomposition of TiC_(x)particles.In addition,the driving force of the main destabilization reaction of TiC_(x)in the Al-Si alloys is about 44 times higher than that in the Al alloys without Si addition.This indicates that the presence of solute Si remarkably promotes the subsequent decomposition process of TiC_(x)in the Al-Si alloy melts. 展开更多
关键词 Al-Si alloy TiC_(x)particles DESTABILIZATION First principles calculations Thermodynamics
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葛根软膏联合参花洗剂治疗早期肛裂60例疗效观察 被引量:2
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作者 袁晨晨 薛蓉 郑晨果 《中国肛肠病杂志》 2021年第12期39-41,共3页
为观察葛根软膏外涂联合参花洗剂坐浴治疗早期肛裂的临床效果,将120例早期肛裂患者按随机数字表法分为观察组和对照组,各60例。对照组采用马应龙麝香痔疮膏外涂联合参花洗剂坐浴治疗,观察组采用葛根软膏外涂联合参花洗剂坐浴治疗。观察... 为观察葛根软膏外涂联合参花洗剂坐浴治疗早期肛裂的临床效果,将120例早期肛裂患者按随机数字表法分为观察组和对照组,各60例。对照组采用马应龙麝香痔疮膏外涂联合参花洗剂坐浴治疗,观察组采用葛根软膏外涂联合参花洗剂坐浴治疗。观察2组疗效、疼痛评分、肛管压力及创口愈合时间。结果显示,治疗后,观察组临床疗效优于对照组,疼痛评分及肛管静息压低于对照组,创口愈合时间短于对照组,差异均有统计学意义(P <0.05)。肛管最大缩榨压及最大缩榨压持续时间2组比较,差异无统计学意义(P>0.05)。结果表明,葛根软膏外涂联合参花洗剂坐浴治疗早期肛裂能减轻疼痛程度,降低肛管静息压,加快创口愈合,有效缓解临床症状及体征。 展开更多
关键词 肛裂 葛根软膏 参花洗剂 疗效
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Cadmium sulfide cage photocatalysis coupled electroactive biofilm for synergistic promotion of tetracycline degradation and electricity production
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作者 Z.S.Yuan J.X.Zou +3 位作者 X.L.Zhao J.Y.Shi c.S.guo M.Yan 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2023年第35期86-97,共12页
Tetracycline(TC)as a common broad-spectrum antibiotic,has been frequently detected in soil and sur-face water.It becomes a great threat to the ecological environment.Here,a device of photocatalysis as-sisted microbial... Tetracycline(TC)as a common broad-spectrum antibiotic,has been frequently detected in soil and sur-face water.It becomes a great threat to the ecological environment.Here,a device of photocatalysis as-sisted microbial fuel cell(photo-MFC)was constructed for TC degradation and energy recovery.In this photo-MFC,cadmium sulfide(CdS)cage photocatalysis can degrade most of TC in a short time.While the Co_(3)O_(4)@C-CC(carbonization and calcination of the ZIF-67 precursor in-situ grown on the carbon cloth(CC))bioanode degrades the rest of TC as well as the photocatalytic products,thus improving the miner-alization.The co-existence of photocatalysis with bioanode changes the microbial community structure of the biofilms.The dominant phylum is Geobacter(60.2%)in normal MFC while that in photo-MFC are Pro-teobacteria(43.5%)and Geobacter(33.2%).Therefore,the synergistic effect of photocatalytic degradation and biodegradation achieves a chemical oxygen demand(COD)removal of 98.6%,which is higher than that of normal MFC(77.6%)or single CdS cage photocatalysis(23.8%).In addition,the photogenerated electrons can be transferred to the cathode,which reduces their combination with holes and increases the electricity generation of MFC,achieving a maximum power density of 3.37 W/m^(2).After degradation,the effluent with 200 mg L^(−1) TC exhibits no visible biotoxity.Furthermore,electrochemical test,finite-difference time-domain(FDTD),density functional theory(DFT)calculation and the free radical trapping experiments verify the possible mechanisms of photocatalytic degradation in this photo-MFC.This strat-egy paves a new way for low energy consumption removal and energy recovery of organic pollutants. 展开更多
关键词 Photo-MFC CdS cage Tetracycline degradation MINERALIZATION Electricity production
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保守和手术治疗儿童MeyersⅢ型胫骨髁间棘骨折临床疗效分析 被引量:6
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作者 冯超 万世奇 +1 位作者 郭源 田伟 《中华小儿外科杂志》 CSCD 2017年第5期324-330,共7页
目的对闭合复位石膏固定及关节镜下复位可吸收钉固定治疗新鲜MeyersⅢ型儿童胫骨髁间棘骨折进行临床疗效比较。 方法2010年6月至2013年6月间我科接诊的新鲜MeyersⅢ型儿童胫骨髁间棘骨折患儿,在关节镜组医生首诊的患儿共12例(12膝)... 目的对闭合复位石膏固定及关节镜下复位可吸收钉固定治疗新鲜MeyersⅢ型儿童胫骨髁间棘骨折进行临床疗效比较。 方法2010年6月至2013年6月间我科接诊的新鲜MeyersⅢ型儿童胫骨髁间棘骨折患儿,在关节镜组医生首诊的患儿共12例(12膝),进行关节镜下复位可吸收钉固定,均获得随访,作为I组;同期非关节镜组医生首诊的患儿共19例(19膝),进行闭合复位石膏固定治疗,其中16例(16膝)获得随访,按照年龄(±1岁)、性别选择其中的12例与I组进行匹配,作为II组。Lysholm评分评价膝关节功能,Lachnmn试验、轴移试验评价膝关节稳定性,KT1000记录双侧膝关节松弛度差异,术后平片按照Wilfinger给出的X线评价标准分级,评价骨折愈合情况及是否存在骨骺早闭。应用PASS软件(V11.0.7,美国NCSS公司)确定所需样本量。应用两个独立样本Wilcoxon秩和检验对两组Lysholm评分进行分析,应用两个独立样本t检验对两组KT1000测量值进行分析,应用Fisher精确概率χ2检验对两组Wilfinger X线分级C及D级占比进行分析。 结果男性每组各4例,女性每组各8例;年龄8~14岁,平均年龄10岁3个月。平均随访时间24个月(18~48个月)。I组12例骨折均获得并维持满意的复位,无内固定断裂、骨块松动、感染、滑膜炎等并发症发生,末次随访时无关节活动受限,膝关节Lysholm功能评分(97.5±2.0)分,Lachnmn试验、轴移试验均阴性,术后3个月内X线显示骨性愈合,按照Wilfinger给出的X线评价标准A 6例,B 4例,C 2例,末次随访时X线检查未见骺板早闭现象。II组末次随访时2例存在5°~10°伸直受限,Lysholm膝关节功能评分(88.0±7.2)分,与I组比较差异具有统计学意义(U=16.500,W=94.500,Z=-3.273,P=0.001〈0.05), Lachnmn试验5例阳性、轴移试验2例阳性,X线评价B 2例,C 6例,D 4例,两组Wi 展开更多
关键词 外科手术 关节镜 儿童 胫骨骨折
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Cognition on oxidation behavior of Ni-based superalloy GH4742 when exposed to water vapor
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作者 H.Xu S.F.Yang +4 位作者 E.H.Wang c.Y.guo Y.S.Liu X.M.Hou Y.L.Zhang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2024年第7期15-22,共8页
The oxidation behavior of Ni-based superalloy GH4742 exposed to water vapor was investigated at 900-1100℃for 50 h in Ar+20%H_(2)O,with Ar+20%O_(2)included for comparison.The presence of H_(2)O is adverse to formation... The oxidation behavior of Ni-based superalloy GH4742 exposed to water vapor was investigated at 900-1100℃for 50 h in Ar+20%H_(2)O,with Ar+20%O_(2)included for comparison.The presence of H_(2)O is adverse to formation of continuous Cr_(2)O_(3)oxide layer but contributes to generation of big voids.Based on this,Ni^(2+)and Co^(2+)are more easily to diffuse towards the outermost oxide layer(OOL),forming non-protective Ni-and Co-rich oxides with high proportion.This leads to a higher weight gain in Ar+20%H_(2)O than that in Ar+20%O_(2).At elevated temperatures,the spallation of oxide scale occurs while the consumption of Cr is reduced in Ar+20%H_(2)O,and the contents of Ni-and Co-rich oxides at this moment are reduced in the OOL.The oxidation mechanism was also discussed. 展开更多
关键词 GH4742 SUPERALLOY H_(2)O Diffusion OXIDATION Mechanism
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红景天苷对成骨细胞的作用及相关分子机制研究 被引量:5
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作者 梅国华 郭小芹 +2 位作者 陈京京 王越 李正阳 《口腔医学研究》 CAS 北大核心 2017年第9期916-919,共4页
目的:研究红景天苷(SAL)对人成骨样MG-63细胞增殖、分化和HIF-1α依赖的VEGF表达的影响及相关分子机制。方法:采用MTS法、流式细胞术分析、RT-PCR、ELISA、Western blot等技术观察SAL对MG-63细胞增殖、分化和HIF-1α依赖的VEGF表达的影... 目的:研究红景天苷(SAL)对人成骨样MG-63细胞增殖、分化和HIF-1α依赖的VEGF表达的影响及相关分子机制。方法:采用MTS法、流式细胞术分析、RT-PCR、ELISA、Western blot等技术观察SAL对MG-63细胞增殖、分化和HIF-1α依赖的VEGF表达的影响,进一步探讨其相关分子机制。结果:SAL通过调控MG-63细胞的周期分布及上调Runx2和Osterix表达促进成骨细胞的增殖和分化。另外,SAL可明显上调下游靶基因VEGF的表达。结论:SAL可显著促进成骨样MG-63细胞的增殖、分化以及HIF-1α依赖的VEGF的表达,进而促进骨和血管新生。 展开更多
关键词 红景天苷 成骨细胞 低氧诱导因子 血管内皮生长因子
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德性、自由与“有根的全球哲学”——关于“进步儒学”与“自由儒学”的对话 被引量:2
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作者 安靖如 郭萍 《齐鲁学刊》 CSSCI 北大核心 2017年第4期53-60,共8页
2017年4月26日,美国著名儒家学者安靖如(Stephen C.Angle)教授应邀来到山东大学中心校区,与山东社会科学院青年儒家学者郭萍博士就"有根的全球哲学"、"进步儒学"和"自由儒学"的相关问题进行了一次对话。... 2017年4月26日,美国著名儒家学者安靖如(Stephen C.Angle)教授应邀来到山东大学中心校区,与山东社会科学院青年儒家学者郭萍博士就"有根的全球哲学"、"进步儒学"和"自由儒学"的相关问题进行了一次对话。安靖如先生指出,他所创建的"进步儒学"是一种"有根的全球哲学",与"综合儒学"在方法论上有着根本的区别:前者是基于单一传统认可意义上"有根的"发展,后者是"双重认可"意义上"综合性的"发展。二者虽然表面近似,而且各有好处,但作为儒家学者必须对此加以区分,以便弄清各种儒学理论据以展开的价值立场和思路方法。对此,致力于创建"自由儒学"理论的郭萍博士提出了自己的理解,并且从"有根的"和"全球的"维度上介绍了"自由儒学"的理论特质。进而,双方基于各自的理论视角,就现代语境下的儒家德性观念以及自由平等与个体权利、美国儒学研究的转向等问题做了广泛地交流,由此在保持各自不同的理论思考的同时,体现出双方坚持立足儒学传统,发展现代价值的思想共识。 展开更多
关键词 有根的全球哲学 进步儒学 自由儒学 德性 自由
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