The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholest...The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholesterol, serum testosterone, FSH and LH) were carried out using Cypress and ELISA kits respectively. The chemical screening of the extract was conducted through tube reactions, the principle of which involves adding a reagent to a quantity of the extract, and subsequently observing the resulting reactions such as precipitation and color change. The results obtained showed that oral administration of the aqueous extract of Tetracarpidium conophorum (250 and 500 mg/kg) produced a significant increase (p Tetracarpidium conophorum kernels at the doses studied produced a very significant decrease in total cholesterol levels (p Tetracarpidium conophorum kernels could have hypocholesterolemic and steroidogenic potential. A study of the aqueous extract of Tetracarpidium conophorum on semen quality and oxidative stress parameters deserves to be conducted.展开更多
The present study was carried out with the objective of evaluating, in castrated rats, the utero trophic, hormonal and biochemical activities of aqueous extracts of Buchholzia coriacea (BC) and Cogniauxia podolaena (C...The present study was carried out with the objective of evaluating, in castrated rats, the utero trophic, hormonal and biochemical activities of aqueous extracts of Buchholzia coriacea (BC) and Cogniauxia podolaena (CP) leaves. Each extract administered at the dose of 600 mg/Kg in castrated rats did not cause a significant change in the fresh weight/dry weight ratio of the uterus compared to castrated rats given distilled water. However, those receiving 17-β-estradiol as a reference product showed a significant (p < 0.5) increase in this ratio. These results indicate the absence of uterotrophic effects of both extracts in the ovariectomized rat compared with the effects of 17-β estradiol. In addition, the extracts did not cause significant changes in estrogen or progesterone levels in treated rats, as observed with 17-β-estradiol. In addition, the determination of protein and total cholesterol in the uterus of castrated rats treated with each extract did not show significant variation from controls. At the time, castrated rats treated with 17-β-estradiol showed a significant increase (p < 0.5) in uterine protein level and a significant decrease (p < 0.5) in total cholesterol level. Only the blood protein level was significantly increased in the castrated rats that received the extracts. These results suggest that the respective estrogenic and progesterone effects of the extracts of the two plants may be ovarian-dependent, these plants would not contain phytohormones.展开更多
文摘The main aim of this study was to evaluate the steroidogenic effects and phytochemical profile of aqueous extract of Tetracarpidium conophorum in male rats. Assays of biochemical reproductive parameters (total cholesterol, serum testosterone, FSH and LH) were carried out using Cypress and ELISA kits respectively. The chemical screening of the extract was conducted through tube reactions, the principle of which involves adding a reagent to a quantity of the extract, and subsequently observing the resulting reactions such as precipitation and color change. The results obtained showed that oral administration of the aqueous extract of Tetracarpidium conophorum (250 and 500 mg/kg) produced a significant increase (p Tetracarpidium conophorum kernels at the doses studied produced a very significant decrease in total cholesterol levels (p Tetracarpidium conophorum kernels could have hypocholesterolemic and steroidogenic potential. A study of the aqueous extract of Tetracarpidium conophorum on semen quality and oxidative stress parameters deserves to be conducted.
文摘The present study was carried out with the objective of evaluating, in castrated rats, the utero trophic, hormonal and biochemical activities of aqueous extracts of Buchholzia coriacea (BC) and Cogniauxia podolaena (CP) leaves. Each extract administered at the dose of 600 mg/Kg in castrated rats did not cause a significant change in the fresh weight/dry weight ratio of the uterus compared to castrated rats given distilled water. However, those receiving 17-β-estradiol as a reference product showed a significant (p < 0.5) increase in this ratio. These results indicate the absence of uterotrophic effects of both extracts in the ovariectomized rat compared with the effects of 17-β estradiol. In addition, the extracts did not cause significant changes in estrogen or progesterone levels in treated rats, as observed with 17-β-estradiol. In addition, the determination of protein and total cholesterol in the uterus of castrated rats treated with each extract did not show significant variation from controls. At the time, castrated rats treated with 17-β-estradiol showed a significant increase (p < 0.5) in uterine protein level and a significant decrease (p < 0.5) in total cholesterol level. Only the blood protein level was significantly increased in the castrated rats that received the extracts. These results suggest that the respective estrogenic and progesterone effects of the extracts of the two plants may be ovarian-dependent, these plants would not contain phytohormones.
