<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:Verdana;"> Extrapulmonary tuberculosis (EPTB) remains difficult to diagnose becaus...<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:Verdana;"> Extrapulmonary tuberculosis (EPTB) remains difficult to diagnose because the clinical specimens to be examined are often paucibacillary</span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> and obtained with difficulty from inaccessible sites. </span><span style="font-family:Verdana;">An updated Xpert<sup></sup></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style="white-space:nowrap;">®</span></sup></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> MTB/RIF Ultra (Ultra) test has been designed and licensed to improve sensitivity in the detection of Mycobacterium tuberculosis complex.</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> The aim of the present study is to evaluate the performance of Ultra assay for the clinical diagnosis of EPTB in </span><span style="font-family:Verdana;">a low tuberculosis prevalence country. </span><span style="font-family:Verdana;"><b></b></span><b><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"></span></b></span><span style="font-family:Verdana;"> A retrospective analysis was performed at “A.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">O dei Colli” of Naples on consecutive extrapulmonary specimens for EPTB across a three-year period. All different types of extrapulmonary specimens were tested for EPTB by smear microscopy, culture and Ultra assay in accordance with relevant guidelines. </span><span style="font-family:Verdana;"><b></b></span><b><b><span style="font-family:Verdana;">R展开更多
文摘<b><span style="font-family:Verdana;">Background:</span></b><span style="font-family:Verdana;"> Extrapulmonary tuberculosis (EPTB) remains difficult to diagnose because the clinical specimens to be examined are often paucibacillary</span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> and obtained with difficulty from inaccessible sites. </span><span style="font-family:Verdana;">An updated Xpert<sup></sup></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><sup><span style="white-space:nowrap;">®</span></sup></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> MTB/RIF Ultra (Ultra) test has been designed and licensed to improve sensitivity in the detection of Mycobacterium tuberculosis complex.</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> The aim of the present study is to evaluate the performance of Ultra assay for the clinical diagnosis of EPTB in </span><span style="font-family:Verdana;">a low tuberculosis prevalence country. </span><span style="font-family:Verdana;"><b></b></span><b><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"></span></b></span><span style="font-family:Verdana;"> A retrospective analysis was performed at “A.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">O dei Colli” of Naples on consecutive extrapulmonary specimens for EPTB across a three-year period. All different types of extrapulmonary specimens were tested for EPTB by smear microscopy, culture and Ultra assay in accordance with relevant guidelines. </span><span style="font-family:Verdana;"><b></b></span><b><b><span style="font-family:Verdana;">R
