Objective: To discover effect on decoction of Huoxuejiangu in avascular necrosis of femoral head(ANFH) in rabbits causing by steroid. Method: 18 rabbits were divided into 3 groups randomly, which were steroid group, C...Objective: To discover effect on decoction of Huoxuejiangu in avascular necrosis of femoral head(ANFH) in rabbits causing by steroid. Method: 18 rabbits were divided into 3 groups randomly, which were steroid group, Chinese herb+steriod group and control group alternatively, each contained 6 rabbits. All rabbits were killed 8 weeks later and the number of empty bone lacunas, hemorheological property and level of serum lipoid were analysed. Results: The decoction of Huoxuejiangu can decrease the viscosity of the blood, increase the deformability of the red blood cells, decrease the level of serum lipoid, and decrease the number of the empty bone lacunas. Conclusion: The decoction of Huoxuejiangu can prevent and treat the ANFH.展开更多
目的:探讨活血通脉汤对脑缺血再灌注大鼠脑组织TN F-α、IC A M-1的影响。方法:制作脑缺血再灌注模型,70只大鼠随机平均分为活血通脉汤组、阿司匹林组、手术组和假手术对照组,应用免疫组织化学方法分别测定缺血再灌注24h、48h脑组织TN F...目的:探讨活血通脉汤对脑缺血再灌注大鼠脑组织TN F-α、IC A M-1的影响。方法:制作脑缺血再灌注模型,70只大鼠随机平均分为活血通脉汤组、阿司匹林组、手术组和假手术对照组,应用免疫组织化学方法分别测定缺血再灌注24h、48h脑组织TN F-α、IC A M-1表达的改变情况。结果:手术组大鼠脑缺血再灌注24h、48h脑皮质TN F-α、IC A M-1表达显著高于假手术对照组(P<0.01),缺血再灌注48h IC A M-1表达低于24h(P<0.05)。使用活血通脉汤治疗能降低TN F-α、IC A M-1表达水平,减轻缺血脑组织神经元坏死的程度。结论:活血通脉汤对脑缺血再灌注具有保护作用,其机制与其降低TN F-α、IC A M-1的表达,从而减少神经元坏死有关。展开更多
文摘Objective: To discover effect on decoction of Huoxuejiangu in avascular necrosis of femoral head(ANFH) in rabbits causing by steroid. Method: 18 rabbits were divided into 3 groups randomly, which were steroid group, Chinese herb+steriod group and control group alternatively, each contained 6 rabbits. All rabbits were killed 8 weeks later and the number of empty bone lacunas, hemorheological property and level of serum lipoid were analysed. Results: The decoction of Huoxuejiangu can decrease the viscosity of the blood, increase the deformability of the red blood cells, decrease the level of serum lipoid, and decrease the number of the empty bone lacunas. Conclusion: The decoction of Huoxuejiangu can prevent and treat the ANFH.
文摘目的:探讨活血通脉汤对脑缺血再灌注大鼠脑组织TN F-α、IC A M-1的影响。方法:制作脑缺血再灌注模型,70只大鼠随机平均分为活血通脉汤组、阿司匹林组、手术组和假手术对照组,应用免疫组织化学方法分别测定缺血再灌注24h、48h脑组织TN F-α、IC A M-1表达的改变情况。结果:手术组大鼠脑缺血再灌注24h、48h脑皮质TN F-α、IC A M-1表达显著高于假手术对照组(P<0.01),缺血再灌注48h IC A M-1表达低于24h(P<0.05)。使用活血通脉汤治疗能降低TN F-α、IC A M-1表达水平,减轻缺血脑组织神经元坏死的程度。结论:活血通脉汤对脑缺血再灌注具有保护作用,其机制与其降低TN F-α、IC A M-1的表达,从而减少神经元坏死有关。
