Through systematic experimental and clinical studies,the physiological regulation of utero-placental circulation and the relation of the disturbance in this acirculation to pathogenic mechanisms of high risk pregnanci...Through systematic experimental and clinical studies,the physiological regulation of utero-placental circulation and the relation of the disturbance in this acirculation to pathogenic mechanisms of high risk pregnancies-Intrauterine Growth Retardation (IUfGR)and Pregnancy-induced hypertension(PIH) were explored.The pharmacological effects and mechanism of a Chinese herbal medicine-Qingxintong in improving the uteroplacental circulation and the therapeutic efficacy in treatment of IUGR and PIH,both accompanied by disturbance of utero-placental circulation.were investigated as well.展开更多
The changes of globulin and complements in placental villi blood vessels were immunohistochemically studied in pregnancy induced hypertension patients and normal pregnant patients by a randomized , double-blind approa...The changes of globulin and complements in placental villi blood vessels were immunohistochemically studied in pregnancy induced hypertension patients and normal pregnant patients by a randomized , double-blind approach. The immunostaining of IgG, IgE, C3, C4, and 5-HT was seen in the villous blood vessels and the helicine arteries of pregnancy induced hypertensive placental villi.The strong positive rates were 100%, 90%, 100%, 100% and 90% in seriouspregnancy induced hypertensive patients, accompanied by aggregation of mastocytes and vasculopathy of villous blood vessels and the helicine arteries. It is concluded that the immuno-pathological damage took place in the villous blood vessels and helicine arteries, resulting in vasculopathy and villous regressive changesand that the immunological factors were closely related to pregnancy induced hypertension.展开更多
文摘Through systematic experimental and clinical studies,the physiological regulation of utero-placental circulation and the relation of the disturbance in this acirculation to pathogenic mechanisms of high risk pregnancies-Intrauterine Growth Retardation (IUfGR)and Pregnancy-induced hypertension(PIH) were explored.The pharmacological effects and mechanism of a Chinese herbal medicine-Qingxintong in improving the uteroplacental circulation and the therapeutic efficacy in treatment of IUGR and PIH,both accompanied by disturbance of utero-placental circulation.were investigated as well.
文摘The changes of globulin and complements in placental villi blood vessels were immunohistochemically studied in pregnancy induced hypertension patients and normal pregnant patients by a randomized , double-blind approach. The immunostaining of IgG, IgE, C3, C4, and 5-HT was seen in the villous blood vessels and the helicine arteries of pregnancy induced hypertensive placental villi.The strong positive rates were 100%, 90%, 100%, 100% and 90% in seriouspregnancy induced hypertensive patients, accompanied by aggregation of mastocytes and vasculopathy of villous blood vessels and the helicine arteries. It is concluded that the immuno-pathological damage took place in the villous blood vessels and helicine arteries, resulting in vasculopathy and villous regressive changesand that the immunological factors were closely related to pregnancy induced hypertension.
