Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. ...Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C 1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.展开更多
Two new steroidal glycosides and one polyhydroxylated sterol were isolated from the soft coral Cladiella sp. by HPLC fractionation. The animal material was collected from Sanya bay, Hainan province, China. On the basi...Two new steroidal glycosides and one polyhydroxylated sterol were isolated from the soft coral Cladiella sp. by HPLC fractionation. The animal material was collected from Sanya bay, Hainan province, China. On the basis of spectroscopic analysis and chemical conversion, their chemical structures were elucidated as pregn-5,20-dien-3β-ol-3-O-α-L-fucopyranoside(1), pregn-5,20-dien-3β-ol-3-O-β-D-xylopyranoside(2) and (22E,24R)-ergost-7,22-dien-3β,5α,6β-triol(3). Compounds 1 and 2 are new compounds.展开更多
文摘Two diterpene lactones, sarcophinone(1) and iso sarcophinone(2), which are biogenetically related to the sarcophine, were isolated from the soft coral Sarcophyton molle Tix. Dur. iso Sarcophinone 2 is a new compound. Its structure was determined to be C 1 epimer of sarcophinone by spectroscopic methods. Bioassay showed that both sarcophinone(1) and iso sarcophinone(2) had potent cytotoxicity toward Ehrlich and S180 tumor cell lines.
文摘Two new steroidal glycosides and one polyhydroxylated sterol were isolated from the soft coral Cladiella sp. by HPLC fractionation. The animal material was collected from Sanya bay, Hainan province, China. On the basis of spectroscopic analysis and chemical conversion, their chemical structures were elucidated as pregn-5,20-dien-3β-ol-3-O-α-L-fucopyranoside(1), pregn-5,20-dien-3β-ol-3-O-β-D-xylopyranoside(2) and (22E,24R)-ergost-7,22-dien-3β,5α,6β-triol(3). Compounds 1 and 2 are new compounds.
