目的观察针刺治疗对功能性消化不良(FD)患者的临床疗效,并探讨针刺治疗的病理生理学机制。方法选取符合标准的FD患者82例,2组患者均采用常规消化内科治疗方案进行治疗。治疗组在此基础上采用循经取穴法,选取足三里、中脘、内关、天枢、...目的观察针刺治疗对功能性消化不良(FD)患者的临床疗效,并探讨针刺治疗的病理生理学机制。方法选取符合标准的FD患者82例,2组患者均采用常规消化内科治疗方案进行治疗。治疗组在此基础上采用循经取穴法,选取足三里、中脘、内关、天枢、期门、阳陵泉穴位进行针刺治疗,对照组则采用假穴位针刺法,2组患者均每日治疗1次,5次为1个疗程,每个疗程间隔2 d,连续治疗4个疗程。均于治疗前和治疗4周后采用功能性胃肠病罗马III症状评分量表和疗效指数对2组患者的疗效进行评估,并进行近端胃敏感性和适应性功能以及胃排空功能评估。结果治疗后2组罗马III症状积分和治疗前组内比较均降低,差异均有统计学意义(P<0.05),且治疗组(9.56±2.18)和对照组(15.68±3.09)比较,差异有统计学意义(P<0.05)。治疗组临床总有效率(75.6%)高于对照组(41.5%),差异有统计学意义(P<0.05);治疗后治疗组初始阈值和最大饱足感阈值(331.46±15.72 & 974.68±93.05)ml与治疗前比较均显著增大,差异均有统计学意义(P<0.05),且治疗组与对照组比较,差异均有统计学意义(P<0.05)。治疗后治疗组胃排空率(GET1 h 69.01±0.06 & GET2 h 76.45±0.09)%,与对照组比较显著提高,差异均有统计学意义(P<0.05)。结论穴位针刺可改善FD患者临床症状,提高近端胃功能,促进胃排空。展开更多
In this work, we demonstrate the CoOOH/（Ti,C）-Fe2O3（CTCF） nanorods prepared by a facile approach as well as their implementation as photoanodes for photoelectrochemical（PEC） water splitting. The photocurrent den...In this work, we demonstrate the CoOOH/（Ti,C）-Fe2O3（CTCF） nanorods prepared by a facile approach as well as their implementation as photoanodes for photoelectrochemical（PEC） water splitting. The photocurrent density of CTCF photoanode is 1.85 m A cm-2 at ＋1.23 V vs. reversible hydrogen electrode（RHE）, which is more than 20 times higher than that of pristine α-Fe2O3 photoanode（0.08 m A cm-2）. The incident-photo-to-current conversion efficiency, applied bias photo-to-current efficiency and transfer efficiency of CTCF photoanode reaches 31.2% at 380 nm（＋1.23 V vs. RHE）,0.11%（＋1.11 V vs. RHE）, 68.2%（＋1.23 V vs. RHE） respectively, which are much higher than those of pristine α-Fe2O3 photoanode. Additionally, the longtime irradiation PEC water splitting of CTCF photoanode demonstrates its high stability at extreme voltage in NaOH（pH 14）.展开更多
文摘目的观察针刺治疗对功能性消化不良(FD)患者的临床疗效,并探讨针刺治疗的病理生理学机制。方法选取符合标准的FD患者82例,2组患者均采用常规消化内科治疗方案进行治疗。治疗组在此基础上采用循经取穴法,选取足三里、中脘、内关、天枢、期门、阳陵泉穴位进行针刺治疗,对照组则采用假穴位针刺法,2组患者均每日治疗1次,5次为1个疗程,每个疗程间隔2 d,连续治疗4个疗程。均于治疗前和治疗4周后采用功能性胃肠病罗马III症状评分量表和疗效指数对2组患者的疗效进行评估,并进行近端胃敏感性和适应性功能以及胃排空功能评估。结果治疗后2组罗马III症状积分和治疗前组内比较均降低,差异均有统计学意义(P<0.05),且治疗组(9.56±2.18)和对照组(15.68±3.09)比较,差异有统计学意义(P<0.05)。治疗组临床总有效率(75.6%)高于对照组(41.5%),差异有统计学意义(P<0.05);治疗后治疗组初始阈值和最大饱足感阈值(331.46±15.72 & 974.68±93.05)ml与治疗前比较均显著增大,差异均有统计学意义(P<0.05),且治疗组与对照组比较,差异均有统计学意义(P<0.05)。治疗后治疗组胃排空率(GET1 h 69.01±0.06 & GET2 h 76.45±0.09)%,与对照组比较显著提高,差异均有统计学意义(P<0.05)。结论穴位针刺可改善FD患者临床症状,提高近端胃功能,促进胃排空。
基金preliminarily supported by the National Natural Science Foundation of China (21706295, 51772135 and 21376104)the Natural Science Foundation of Guangdong Province (2017A030313055 and 2014A030306010Jinan University (11617326 and 88017418)
文摘In this work, we demonstrate the CoOOH/（Ti,C）-Fe2O3（CTCF） nanorods prepared by a facile approach as well as their implementation as photoanodes for photoelectrochemical（PEC） water splitting. The photocurrent density of CTCF photoanode is 1.85 m A cm-2 at ＋1.23 V vs. reversible hydrogen electrode（RHE）, which is more than 20 times higher than that of pristine α-Fe2O3 photoanode（0.08 m A cm-2）. The incident-photo-to-current conversion efficiency, applied bias photo-to-current efficiency and transfer efficiency of CTCF photoanode reaches 31.2% at 380 nm（＋1.23 V vs. RHE）,0.11%（＋1.11 V vs. RHE）, 68.2%（＋1.23 V vs. RHE） respectively, which are much higher than those of pristine α-Fe2O3 photoanode. Additionally, the longtime irradiation PEC water splitting of CTCF photoanode demonstrates its high stability at extreme voltage in NaOH（pH 14）.
