磷酸腺苷蛋白激酶（AMP－activated protein kinase，AMPK）是一种调节细胞内能量代谢的酶。它的主要特征是能与AMP结合，并通过AMP感知细胞的能量水平和代谢平衡水平来调节酶的活性。AMPK通过调整血糖水平、脂肪酸氧化和糖原代谢在糖...磷酸腺苷蛋白激酶（AMP－activated protein kinase，AMPK）是一种调节细胞内能量代谢的酶。它的主要特征是能与AMP结合，并通过AMP感知细胞的能量水平和代谢平衡水平来调节酶的活性。AMPK通过调整血糖水平、脂肪酸氧化和糖原代谢在糖尿病及肥胖症等多种代谢性疾病的发病中发挥至关重要的作用。近年来，学者们认识到AMPK在糖尿病心血管疾病保护中的起着重要作用。展开更多
The characteristics of compound particle multiplicity distribution and multiplicity correlations between the compound particle and the grey particle, black particle, shower particle and heavily ionized track particle ...The characteristics of compound particle multiplicity distribution and multiplicity correlations between the compound particle and the grey particle, black particle, shower particle and heavily ionized track particle are investigated in this paper. It is found that the average multiplicities of the grey particle, black particle, shower particle and heavily ionized track particle increase with an increase in the number of compound particles, which can be explained by the impact geometrical model. The compound multiplicity distribution is observed to obey a Koba-Nielson-Olesen （KNO） type of scaling law.展开更多
[Objective] The aim of this work was to identify molecular weight （MW） distribution and antioxidant activity of fish skin col agen hydrolysates. [Method] The MW distribution of hydrolysates was determined using both...[Objective] The aim of this work was to identify molecular weight （MW） distribution and antioxidant activity of fish skin col agen hydrolysates. [Method] The MW distribution of hydrolysates was determined using both size exclusion chromatography and matrix-assisted laser desorption ionization time-of-flight mass spec-trometry （MALDI-TOF-MS）. Fish skin were treated by the alkaline protease 2709. [Result] The optional conditions for hyerolysis were time 3 h, temperature 55 ℃, pH 10.0, substrate concentration 80 g/L and E/S 4%. The results of both methods indi-cated that the molecular weight of col agen hydrolysates was from 400 to 1 800 Da, and the peptides’ molecular weight was less than 1 400 Da mostly. The reducing power and antioxidant/radical scavenging activity [1, 1-diphenyl-2-picryl-hydrazyl （DPPH） free radical scavenging activity] were determined. [Conclusion] The results reveal that the fishskin hydrolysate is a potential source of antioxidants.展开更多
文摘磷酸腺苷蛋白激酶（AMP－activated protein kinase，AMPK）是一种调节细胞内能量代谢的酶。它的主要特征是能与AMP结合，并通过AMP感知细胞的能量水平和代谢平衡水平来调节酶的活性。AMPK通过调整血糖水平、脂肪酸氧化和糖原代谢在糖尿病及肥胖症等多种代谢性疾病的发病中发挥至关重要的作用。近年来，学者们认识到AMPK在糖尿病心血管疾病保护中的起着重要作用。
基金Supported by National Natural Science Foundation of China (10475054)Natural Foundation of Shanxi Province, China(2008011005)Shanxi Provincial Foundation for Returned Scholars of China
文摘The characteristics of compound particle multiplicity distribution and multiplicity correlations between the compound particle and the grey particle, black particle, shower particle and heavily ionized track particle are investigated in this paper. It is found that the average multiplicities of the grey particle, black particle, shower particle and heavily ionized track particle increase with an increase in the number of compound particles, which can be explained by the impact geometrical model. The compound multiplicity distribution is observed to obey a Koba-Nielson-Olesen （KNO） type of scaling law.
基金Supported by Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi,China(2010127)~~
文摘[Objective] The aim of this work was to identify molecular weight （MW） distribution and antioxidant activity of fish skin col agen hydrolysates. [Method] The MW distribution of hydrolysates was determined using both size exclusion chromatography and matrix-assisted laser desorption ionization time-of-flight mass spec-trometry （MALDI-TOF-MS）. Fish skin were treated by the alkaline protease 2709. [Result] The optional conditions for hyerolysis were time 3 h, temperature 55 ℃, pH 10.0, substrate concentration 80 g/L and E/S 4%. The results of both methods indi-cated that the molecular weight of col agen hydrolysates was from 400 to 1 800 Da, and the peptides’ molecular weight was less than 1 400 Da mostly. The reducing power and antioxidant/radical scavenging activity [1, 1-diphenyl-2-picryl-hydrazyl （DPPH） free radical scavenging activity] were determined. [Conclusion] The results reveal that the fishskin hydrolysate is a potential source of antioxidants.
