It has long been known that actinomycin D (AMD) strongly inhibits DNA-dependent RNA synthesis. But there exist discrepancies of opinon or even contradictions of evidences for its effect on the replication of viruses (...It has long been known that actinomycin D (AMD) strongly inhibits DNA-dependent RNA synthesis. But there exist discrepancies of opinon or even contradictions of evidences for its effect on the replication of viruses (as well as bacteriophages) containing RNA as genome. Snger and Knight reported that TMV-RNA synthesis was not inhibited by AMD, thus they considered that the template function of DNA was not involved in the synthesis of the viral RNA.展开更多
文摘It has long been known that actinomycin D (AMD) strongly inhibits DNA-dependent RNA synthesis. But there exist discrepancies of opinon or even contradictions of evidences for its effect on the replication of viruses (as well as bacteriophages) containing RNA as genome. Snger and Knight reported that TMV-RNA synthesis was not inhibited by AMD, thus they considered that the template function of DNA was not involved in the synthesis of the viral RNA.
