Objective： To observe the clinical efficacy of warm needling moxibustion plus flash cupping for remission-stage peripheral facial paralysis （FP） due to wind-cold. Methods： Fifty eligible patients were randomized i...Objective： To observe the clinical efficacy of warm needling moxibustion plus flash cupping for remission-stage peripheral facial paralysis （FP） due to wind-cold. Methods： Fifty eligible patients were randomized into a warm needling moxibustion group and an acupuncture-cupping group, 25 cases in each group. The warm needling moxibustion group was intervened by acupuncture at Fengchi （GB 20）, Yangbai （GB 14） towards Yuyao （EX-HN 4）, Xiaguan （ST 7）, Dicang （ST 4） towards Jiache （ST 6）, Quanliao （SI 18）, and Hegu （LI 4）, plus warm needling moxibustion at Quanliao （SI 18）; the acupuncture-cupping group received flash cupping on the affected side in addition to the intervention given to the warm needling moxibustion group. The two groups were both treated once a day, 10 times as a treatment course, for 3 courses in total. The House-Brackmann （H-B） facial nerve grading system was observed before and after the intervention to evaluate the facial nerve function in the two groups, and the therapeutic efficacies were also compared between the two groups. Results： The two treatment protocols both can promote the recovery of facial nerve function. The total effective rate was 92.0% in the acupuncture-cupping group versus 72.0% in the warm needling moxibustion group, and the between-group difference was statistically significant （P〈O.05）. Conclusion： Warm needling moxibustion plus flash cupping can produce a more significant efficacy than dry warm needling moxibustion in treating remission-stage peripheral FP due to wind-cold.展开更多
Objective： To observe the effect of acupuncture plus thunder-fire moxibustion on the expressions of matrix metalloproteinase-3 （MMP-3）, tissue inhibitor of metalloproteinase-1 （TIMP-1） and transforming growth fac...Objective： To observe the effect of acupuncture plus thunder-fire moxibustion on the expressions of matrix metalloproteinase-3 （MMP-3）, tissue inhibitor of metalloproteinase-1 （TIMP-1） and transforming growth factor-β1 （TGF-β1） in cartilage of knee osteoarthritis （KOA） rats, and to explore the mechanism of acupuncture plus thunder-fire moxibustion in the treatment of KOA. Methods： Thirty Sprague-Dawley （SD） rats were randomly divided into a blank control group, a model group and an acupuncture-moxibustion group by random digits table, 10 rats in each group. Rats in the model group and the acupuncture-moxibustion group were injected with papain in the right posterior knee joint to prepare the models. The levels of MMP-3 and TIMP-1 in rat synovium of each group were measured by enzyme-linked immunosorbent assay （ELBA） after 2 weeks of treatment. The level of TGF-β1 was determined by Motic B5 Micro-camera system. Results： The levels of MMP-3 and TIMP-1 in the cartilage of the model group were significantly higher than those in the blank control group （all P〈0.01）; the levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were lower than those in the model group, and the between-group differences were statistically significant （all P〈0.05）. The levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were higher than those in the blank control group, and the differences were statistically significant （all P〈0.05）. The level of TGF-β1 in cartilage tissues of the model group was significantly lower than that in the blank control group （P〈0.01）; the level of TGF-β1 in the acupuncture-moxibustion group was higher than that in the model group （P〈0.05）, but it was lower than that in the blank control group, and the between-group difference was statistically significant （P〈0.05）. Conclusion： Acupuncture plus thunder-fire moxibustion can effectively recover the abnormal expressions of MMP-3 and TIMP-1 in KOA model rats and somewhat up-展开更多
基金supported by Project of State Administration of Traditional Chinese Medicine,No.LP0118041~~
文摘Objective： To observe the clinical efficacy of warm needling moxibustion plus flash cupping for remission-stage peripheral facial paralysis （FP） due to wind-cold. Methods： Fifty eligible patients were randomized into a warm needling moxibustion group and an acupuncture-cupping group, 25 cases in each group. The warm needling moxibustion group was intervened by acupuncture at Fengchi （GB 20）, Yangbai （GB 14） towards Yuyao （EX-HN 4）, Xiaguan （ST 7）, Dicang （ST 4） towards Jiache （ST 6）, Quanliao （SI 18）, and Hegu （LI 4）, plus warm needling moxibustion at Quanliao （SI 18）; the acupuncture-cupping group received flash cupping on the affected side in addition to the intervention given to the warm needling moxibustion group. The two groups were both treated once a day, 10 times as a treatment course, for 3 courses in total. The House-Brackmann （H-B） facial nerve grading system was observed before and after the intervention to evaluate the facial nerve function in the two groups, and the therapeutic efficacies were also compared between the two groups. Results： The two treatment protocols both can promote the recovery of facial nerve function. The total effective rate was 92.0% in the acupuncture-cupping group versus 72.0% in the warm needling moxibustion group, and the between-group difference was statistically significant （P〈O.05）. Conclusion： Warm needling moxibustion plus flash cupping can produce a more significant efficacy than dry warm needling moxibustion in treating remission-stage peripheral FP due to wind-cold.
基金supported by Project of State Administration of Traditional Chinese Medicine, No. LP0118041~~
文摘Objective： To observe the effect of acupuncture plus thunder-fire moxibustion on the expressions of matrix metalloproteinase-3 （MMP-3）, tissue inhibitor of metalloproteinase-1 （TIMP-1） and transforming growth factor-β1 （TGF-β1） in cartilage of knee osteoarthritis （KOA） rats, and to explore the mechanism of acupuncture plus thunder-fire moxibustion in the treatment of KOA. Methods： Thirty Sprague-Dawley （SD） rats were randomly divided into a blank control group, a model group and an acupuncture-moxibustion group by random digits table, 10 rats in each group. Rats in the model group and the acupuncture-moxibustion group were injected with papain in the right posterior knee joint to prepare the models. The levels of MMP-3 and TIMP-1 in rat synovium of each group were measured by enzyme-linked immunosorbent assay （ELBA） after 2 weeks of treatment. The level of TGF-β1 was determined by Motic B5 Micro-camera system. Results： The levels of MMP-3 and TIMP-1 in the cartilage of the model group were significantly higher than those in the blank control group （all P〈0.01）; the levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were lower than those in the model group, and the between-group differences were statistically significant （all P〈0.05）. The levels of MMP-3 and TIMP-1 in the acupuncture-moxibustion group were higher than those in the blank control group, and the differences were statistically significant （all P〈0.05）. The level of TGF-β1 in cartilage tissues of the model group was significantly lower than that in the blank control group （P〈0.01）; the level of TGF-β1 in the acupuncture-moxibustion group was higher than that in the model group （P〈0.05）, but it was lower than that in the blank control group, and the between-group difference was statistically significant （P〈0.05）. Conclusion： Acupuncture plus thunder-fire moxibustion can effectively recover the abnormal expressions of MMP-3 and TIMP-1 in KOA model rats and somewhat up-
