Ⅰ. INTRODUCTION It is important to study the differences between normal and tumor cells. To search specific markers of tumor cell are helpful for cancer prognostic and therapeutic. Up to now, the double minute chromo...Ⅰ. INTRODUCTION It is important to study the differences between normal and tumor cells. To search specific markers of tumor cell are helpful for cancer prognostic and therapeutic. Up to now, the double minute chromosome (DM) has been found in neurogenic tumor, in ovary, breast, uterus, colon and thyroid tumors and some tumor cell lines. The cells containing DM resist high levels of methotrexate. In these cells,展开更多
文摘Ⅰ. INTRODUCTION It is important to study the differences between normal and tumor cells. To search specific markers of tumor cell are helpful for cancer prognostic and therapeutic. Up to now, the double minute chromosome (DM) has been found in neurogenic tumor, in ovary, breast, uterus, colon and thyroid tumors and some tumor cell lines. The cells containing DM resist high levels of methotrexate. In these cells,
