BCCIP(BRCA2 And CDKN1A Interacting Protein)是一种进化保守蛋白,参与维持基因组稳定性和细胞周期进程,以具有不同C末端结构域的BCCIPβ及BCCIPα两种类型存在于人类中。BCCIP基因表达是肿瘤抑制中重要的BRCA2辅助因子,其作为肿瘤抑...BCCIP(BRCA2 And CDKN1A Interacting Protein)是一种进化保守蛋白,参与维持基因组稳定性和细胞周期进程,以具有不同C末端结构域的BCCIPβ及BCCIPα两种类型存在于人类中。BCCIP基因表达是肿瘤抑制中重要的BRCA2辅助因子,其作为肿瘤抑制因子在多种肿瘤中起作用。已有研究证实,BCCIP基因在卵巢癌、肾细胞癌及结直肠癌等组织中表达降低,研究也表明,BCCIP的低表达状态成为肝细胞癌患者生存率低的独立预后因素[1-2]。展开更多
We study the properties of dense matter at finite temperature with various proton fractions for use in supernova simulations. The relativistic mean-field theory is used to describe homogeneous nuclear matter, while th...We study the properties of dense matter at finite temperature with various proton fractions for use in supernova simulations. The relativistic mean-field theory is used to describe homogeneous nuclear matter, while the Thomas-Fermi approximation is adopted to describe inhomogeneous matter. We also discuss the equation of state of neutron star matter at zero temperature in a wide density range. The equation of state at high densities can be significantly softened by the inclusion of hyperons.展开更多
文摘BCCIP(BRCA2 And CDKN1A Interacting Protein)是一种进化保守蛋白,参与维持基因组稳定性和细胞周期进程,以具有不同C末端结构域的BCCIPβ及BCCIPα两种类型存在于人类中。BCCIP基因表达是肿瘤抑制中重要的BRCA2辅助因子,其作为肿瘤抑制因子在多种肿瘤中起作用。已有研究证实,BCCIP基因在卵巢癌、肾细胞癌及结直肠癌等组织中表达降低,研究也表明,BCCIP的低表达状态成为肝细胞癌患者生存率低的独立预后因素[1-2]。
基金supported by National Natural Science Foundation of China(Nos.10675064,11075082)
文摘We study the properties of dense matter at finite temperature with various proton fractions for use in supernova simulations. The relativistic mean-field theory is used to describe homogeneous nuclear matter, while the Thomas-Fermi approximation is adopted to describe inhomogeneous matter. We also discuss the equation of state of neutron star matter at zero temperature in a wide density range. The equation of state at high densities can be significantly softened by the inclusion of hyperons.
