目的研究衢州市2011-2013年出生儿童接种1剂麻腮风减毒活疫苗(measles,mumps and rubella combined attenuated live vaccine,MMR)对流行性腮腺炎(流腮)保护效果,为制定流腮防控策略提供依据。方法分别从"中国疾病监测信息报告管...目的研究衢州市2011-2013年出生儿童接种1剂麻腮风减毒活疫苗(measles,mumps and rubella combined attenuated live vaccine,MMR)对流行性腮腺炎(流腮)保护效果,为制定流腮防控策略提供依据。方法分别从"中国疾病监测信息报告管理系统"和"浙江省免疫规划信息系统"中导出衢州市2011-2013年出生儿童的流腮个案和疫苗接种数据,计算接种率、相对危险度和疫苗保护效果(vaccine efficacy,VE)。结果衢州市2011-2013年出生儿童累计报告流腮病例286例,其中无MMR免疫史病例和接种1剂MMR突破病例分别为25例、261例。无免疫史病例和突破病例的出生年份、男女性别构成比无差异,突破病例构成比随着时间延长而增加,免后2~3年发病数最多,且发病时间长于无免疫史病例(t=9.546,P<0.01)。衢州市2011-2013年出生儿童1剂MMR接种及时率分别为91.87%,92.15%,93.16%,累计接种率分别为97.60%,97.46%,97.52%。接种1剂MMR估算总VE为73.5%(95%CI:60.2%~82.4%),在18~23月接种1剂MMR后<2年、2~3年、4~5年的VE分别为92.1%(95%CI:87.6%~94.9%)、86.4%(95%CI:79.1%~91.1%)、94.6%(95%CI:91.3%~96.7%)。结论接种1剂MMR的长期保护效果有限,建议在提高1剂MMR接种及时率的同时,尽早引入2剂MMR常规免疫程序,第2剂在4~6岁接种。展开更多
An azo metal chelate compound with push pull electronic system was synthesized. Smooth thin films were prepared by spin coating. The absorption, transmission and reflection spectra of the films were measured. The opti...An azo metal chelate compound with push pull electronic system was synthesized. Smooth thin films were prepared by spin coating. The absorption, transmission and reflection spectra of the films were measured. The optical constant (complex refractive index N=n +i k ) of the film was determined using scanning ellipsometer, and the complex dielectric function ε as well as absorption coefficient α were then calculated. Dynamic optical recording test indicated that the azo metal chelate dye was a promising candidate as optical recording medium.展开更多
文摘目的研究衢州市2011-2013年出生儿童接种1剂麻腮风减毒活疫苗(measles,mumps and rubella combined attenuated live vaccine,MMR)对流行性腮腺炎(流腮)保护效果,为制定流腮防控策略提供依据。方法分别从"中国疾病监测信息报告管理系统"和"浙江省免疫规划信息系统"中导出衢州市2011-2013年出生儿童的流腮个案和疫苗接种数据,计算接种率、相对危险度和疫苗保护效果(vaccine efficacy,VE)。结果衢州市2011-2013年出生儿童累计报告流腮病例286例,其中无MMR免疫史病例和接种1剂MMR突破病例分别为25例、261例。无免疫史病例和突破病例的出生年份、男女性别构成比无差异,突破病例构成比随着时间延长而增加,免后2~3年发病数最多,且发病时间长于无免疫史病例(t=9.546,P<0.01)。衢州市2011-2013年出生儿童1剂MMR接种及时率分别为91.87%,92.15%,93.16%,累计接种率分别为97.60%,97.46%,97.52%。接种1剂MMR估算总VE为73.5%(95%CI:60.2%~82.4%),在18~23月接种1剂MMR后<2年、2~3年、4~5年的VE分别为92.1%(95%CI:87.6%~94.9%)、86.4%(95%CI:79.1%~91.1%)、94.6%(95%CI:91.3%~96.7%)。结论接种1剂MMR的长期保护效果有限,建议在提高1剂MMR接种及时率的同时,尽早引入2剂MMR常规免疫程序,第2剂在4~6岁接种。
文摘An azo metal chelate compound with push pull electronic system was synthesized. Smooth thin films were prepared by spin coating. The absorption, transmission and reflection spectra of the films were measured. The optical constant (complex refractive index N=n +i k ) of the film was determined using scanning ellipsometer, and the complex dielectric function ε as well as absorption coefficient α were then calculated. Dynamic optical recording test indicated that the azo metal chelate dye was a promising candidate as optical recording medium.
