Organoselenium reagents are powerful tools for the preparation of small organic molecules.A simple preparation of polystyrene-supported（E）-1-bromo-2-selenoethylene was reported.In the presence of NiCl2（PPh3）2 cata...Organoselenium reagents are powerful tools for the preparation of small organic molecules.A simple preparation of polystyrene-supported（E）-1-bromo-2-selenoethylene was reported.In the presence of NiCl2（PPh3）2 catalyst,polystyrene-supported（E）-1-bromo-2-selenoethylene reacted with different Grignard reagents to offer（E）-1,2-disubstituted ethenes or trisubstituted ethenes.The evident advantages of this reaction are easy operations,odorlessness,good yields of the products.展开更多
The organoselenium-induced ring-closure reaction of O-allyl oximes gave cyclic iminium salts, which reacted with Grignard reagents to produce N-alkyl-4-phenylselenoisoxazolidines. 2,5-Dihydroisoxazoles could be obtain...The organoselenium-induced ring-closure reaction of O-allyl oximes gave cyclic iminium salts, which reacted with Grignard reagents to produce N-alkyl-4-phenylselenoisoxazolidines. 2,5-Dihydroisoxazoles could be obtained in good yields by subsequent selenoxide syn-elimination.展开更多
Application of the Suzuki cross-coupling reaction for efficient synthesis of diverse substituted biaryl-chromen- 4-ones using an optimized palladium（0） catalyst system is reported. The coupling of arylboronic acids ...Application of the Suzuki cross-coupling reaction for efficient synthesis of diverse substituted biaryl-chromen- 4-ones using an optimized palladium（0） catalyst system is reported. The coupling of arylboronic acids with the resin-bound bromoflavanones which were prepared by organoselenium-induced regioselective intramolecular cy- clization of bromo-2-hydroxylchalcones proceeded smoothly. Biaryl-chromen-4-ones were synthesized by subse- quent selenoxide syn-elimination in good total yields.展开更多
文摘Organoselenium reagents are powerful tools for the preparation of small organic molecules.A simple preparation of polystyrene-supported（E）-1-bromo-2-selenoethylene was reported.In the presence of NiCl2（PPh3）2 catalyst,polystyrene-supported（E）-1-bromo-2-selenoethylene reacted with different Grignard reagents to offer（E）-1,2-disubstituted ethenes or trisubstituted ethenes.The evident advantages of this reaction are easy operations,odorlessness,good yields of the products.
基金Project supported by the National Natural Science Foundation of China (Nos. 20332060,20272050).
文摘The organoselenium-induced ring-closure reaction of O-allyl oximes gave cyclic iminium salts, which reacted with Grignard reagents to produce N-alkyl-4-phenylselenoisoxazolidines. 2,5-Dihydroisoxazoles could be obtained in good yields by subsequent selenoxide syn-elimination.
文摘Application of the Suzuki cross-coupling reaction for efficient synthesis of diverse substituted biaryl-chromen- 4-ones using an optimized palladium（0） catalyst system is reported. The coupling of arylboronic acids with the resin-bound bromoflavanones which were prepared by organoselenium-induced regioselective intramolecular cy- clization of bromo-2-hydroxylchalcones proceeded smoothly. Biaryl-chromen-4-ones were synthesized by subse- quent selenoxide syn-elimination in good total yields.
