目的：探讨立体定向适形放射治疗肝脏海绵状血管瘤的临床疗效。方法：采用OPEN式KLF-A型全身立体定向适形放射治疗对52例肝海绵状血管瘤患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积（PTV）,给予计划靶体积周边单次剂量350~45...目的：探讨立体定向适形放射治疗肝脏海绵状血管瘤的临床疗效。方法：采用OPEN式KLF-A型全身立体定向适形放射治疗对52例肝海绵状血管瘤患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积（PTV）,给予计划靶体积周边单次剂量350~450 c GY,分8~12次进行治疗,每天1次,总剂量3 500~4 500 c GY,平均4 170 c GY。结果：（1）病灶小于5 cm者20例,其中15例CR、2例PR、2例SD、1例PD;病灶5~10 cm者25例,其中8例CR、13例PR、3例SD、1例PD;病灶大于10~15 cm者7例,其中1例CR、5例PR、1例SD、没有PD。（2）有临床症状者26例,其中临床症状消失21例,减轻3例,无效2例。结论：立体定向伽玛刀治疗肝海绵状血管瘤是安全有效的方法,能显著改善临床症状,不良反应小,患者耐受良好。展开更多
目的探讨立体定向放射治疗中晚期胰腺癌的临床疗效及并发症.方法采用OPEN式KLF-A型全身立体定向放射治疗对268例中晚期胰腺癌患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积(PTV),给予PTV周边单次剂量250 c GY^450 c GY,总剂量3...目的探讨立体定向放射治疗中晚期胰腺癌的临床疗效及并发症.方法采用OPEN式KLF-A型全身立体定向放射治疗对268例中晚期胰腺癌患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积(PTV),给予PTV周边单次剂量250 c GY^450 c GY,总剂量3 000 c GY^4 500 c GY,分8~14次进行治疗,每日治疗一次.结果 268例中晚期胰腺癌患者经立体定向放射治疗系统治疗后,局部止痛有效率:89.2%;黄疸消退率:77.6%;经影像学(CT/MRI)复查的223例:CR 28例,PR 157例,SD 13例,PD 25例,即客观有效率(CR+PR+SD):88.8%.治疗后1 a生存率66.8%,2 a生存率30.0%,3 a生存率9.7%,中位生存期约15个月,无严重并发症发生.结论立体定向放射治疗系统治疗中晚期胰腺癌疗效满意,治疗反应小,可明显改善患者临床症状,减轻痛苦,提高生存质量,提高肿瘤的局控率,是治疗中晚期胰腺癌的一种安全有效方法.展开更多
Phase change material(PCM) can be used to prepare the infrared false targets for realizing all-weather passive infrared decoy,but its low thermal conductivity is a great blockage to the simulation of the infrared sign...Phase change material(PCM) can be used to prepare the infrared false targets for realizing all-weather passive infrared decoy,but its low thermal conductivity is a great blockage to the simulation of the infrared signature of thick metal plates.For that reason,a method of simulating the infrared signature of thick steel plates by thermal conduction enhanced PCM,including the aluminum fins,is proposed.A physical and mathematic model is set up,and the infrared signature simulation of thick steel plate is investigated numerically.The effects of the distribution density and thickness of fins and the thickness of PCM plate on the simulation results are discussed,and the reasonable construction parameters of PCM plates used to simulate the steel plates of different thickness are obtained.展开更多
文摘目的：探讨立体定向适形放射治疗肝脏海绵状血管瘤的临床疗效。方法：采用OPEN式KLF-A型全身立体定向适形放射治疗对52例肝海绵状血管瘤患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积（PTV）,给予计划靶体积周边单次剂量350~450 c GY,分8~12次进行治疗,每天1次,总剂量3 500~4 500 c GY,平均4 170 c GY。结果：（1）病灶小于5 cm者20例,其中15例CR、2例PR、2例SD、1例PD;病灶5~10 cm者25例,其中8例CR、13例PR、3例SD、1例PD;病灶大于10~15 cm者7例,其中1例CR、5例PR、1例SD、没有PD。（2）有临床症状者26例,其中临床症状消失21例,减轻3例,无效2例。结论：立体定向伽玛刀治疗肝海绵状血管瘤是安全有效的方法,能显著改善临床症状,不良反应小,患者耐受良好。
文摘目的探讨立体定向放射治疗中晚期胰腺癌的临床疗效及并发症.方法采用OPEN式KLF-A型全身立体定向放射治疗对268例中晚期胰腺癌患者进行分次治疗,用50%~70%的等剂量曲线覆盖计划靶体积(PTV),给予PTV周边单次剂量250 c GY^450 c GY,总剂量3 000 c GY^4 500 c GY,分8~14次进行治疗,每日治疗一次.结果 268例中晚期胰腺癌患者经立体定向放射治疗系统治疗后,局部止痛有效率:89.2%;黄疸消退率:77.6%;经影像学(CT/MRI)复查的223例:CR 28例,PR 157例,SD 13例,PD 25例,即客观有效率(CR+PR+SD):88.8%.治疗后1 a生存率66.8%,2 a生存率30.0%,3 a生存率9.7%,中位生存期约15个月,无严重并发症发生.结论立体定向放射治疗系统治疗中晚期胰腺癌疗效满意,治疗反应小,可明显改善患者临床症状,减轻痛苦,提高生存质量,提高肿瘤的局控率,是治疗中晚期胰腺癌的一种安全有效方法.
基金Sponsored by National Nature Science Foundation of China (50402009)
文摘Phase change material(PCM) can be used to prepare the infrared false targets for realizing all-weather passive infrared decoy,but its low thermal conductivity is a great blockage to the simulation of the infrared signature of thick metal plates.For that reason,a method of simulating the infrared signature of thick steel plates by thermal conduction enhanced PCM,including the aluminum fins,is proposed.A physical and mathematic model is set up,and the infrared signature simulation of thick steel plate is investigated numerically.The effects of the distribution density and thickness of fins and the thickness of PCM plate on the simulation results are discussed,and the reasonable construction parameters of PCM plates used to simulate the steel plates of different thickness are obtained.
