In many clinical studies it is important to examine whether or not the effect of the treatment varies across patient subgroups [1].For example,does the effect of treatment for depression with a specific SSRI vary by g...In many clinical studies it is important to examine whether or not the effect of the treatment varies across patient subgroups [1].For example,does the effect of treatment for depression with a specific SSRI vary by gender? In other words,is there ’heterogeneity of treatment effects’ (HTE)? This information is important for clinical decision-making;clinicians can target a specific treatment to patients who are expected to benefit most from the treatment and seek alternative treatments for patients who are expected to展开更多
文摘In many clinical studies it is important to examine whether or not the effect of the treatment varies across patient subgroups [1].For example,does the effect of treatment for depression with a specific SSRI vary by gender? In other words,is there ’heterogeneity of treatment effects’ (HTE)? This information is important for clinical decision-making;clinicians can target a specific treatment to patients who are expected to benefit most from the treatment and seek alternative treatments for patients who are expected to