目的通过MRI评估颞下颌关节紊乱病患者髁突位置及形态的变化,为临床提供参考。方法对2011年11月至2019年4月解放军总医院放射科及解放军总医院海南医院放射科门诊就诊的137例临床诊断为颞下颌关节紊乱病的患者[年龄(37.5±16.1)岁,...目的通过MRI评估颞下颌关节紊乱病患者髁突位置及形态的变化,为临床提供参考。方法对2011年11月至2019年4月解放军总医院放射科及解放军总医院海南医院放射科门诊就诊的137例临床诊断为颞下颌关节紊乱病的患者[年龄(37.5±16.1)岁,男性39例,女性98例]进行颞下颌关节MRI扫描,根据关节盘移位情况分为关节盘位置正常组(disc without displacement,DWoD)(185侧关节),关节盘可复性前移位组(anterior disc displacement with reduction,DDWR)(17侧关节)及关节盘不可复性前移位组(disc displacement without reduction,DDWoR)(72侧关节),观察颞下颌关节髁突位置(前位、中立位及后位)和形态(卵圆形、扁平形及鸟嘴形),并在横轴位T2WI图像上测量髁突长轴和短轴长度。根据双侧关节盘移位情况分为正常组(74例)、单侧移位组(40例)及双侧移位组(23例),并在横断面T2WI上测量并比较3组髁间角。结果DWoD组、DDWR组和DDWoR组髁突位置差异无统计学意义(χ^2=7.435,P=0.115)。DWoD组扁平形髁突发生率[83.9%(115/137)]显著高于DDWoR组[50.7%(34/67)](P<0.05),DWoD组鸟嘴形髁突发生率[16.1%(22/137)]显著低于DDWoR组[49.3%(33/67)](P<0.05)。DWoD组髁突长轴长度[(17.2±2.4)mm]显著大于DDWR组[(15.4±2.0)mm]和DDWoR组[(14.7±2.7)mm](P<0.05)。DWoD组髁突短轴长度[(7.3±1.2)mm]显著大于DDWR组[(6.5±1.3)mm]和DDWoR组[(6.1±1.4)mm](P<0.05)。正常组、单侧移位组髁间角(分别为136°±13°和132°±14°)均显著大于双侧移位组(124°±17°)(P<0.05)。结论颞下颌关节紊乱病患者群中颞下颌关节盘移位患者可见髁突形态显著改变。展开更多
Objective To investigate the difference in texture features on diffusion weighted imaging(DWI) images between breast benign and malignant tumors.Methods Patients including 56 with mass-like breast cancer, 16 with brea...Objective To investigate the difference in texture features on diffusion weighted imaging(DWI) images between breast benign and malignant tumors.Methods Patients including 56 with mass-like breast cancer, 16 with breast fibroadenoma, and 4 with intraductal papilloma of breast treated in the Hainan Hospital of Chinese PLA General Hospital were retrospectively enrolled in this study, and allocated to the benign group(20 patients) and the malignant group(56 patients) according to the post-surgically pathological results. Texture analysis was performed on axial DWI images, and five characteristic parameters including Angular Second Moment(ASM), Contrast, Correlation, Inverse Difference Moment(IDM), and Entropy were calculated. Independent sample t-test and Mann-Whitney U test were performed for intergroup comparison. Regression model was established by using Binary Logistic regression analysis, and receiver operating characteristic curve(ROC) analysis was carried out to evaluate the diagnostic efficiency. Results The texture features ASM, Contrast, Correlation and Entropy showed significant differences between the benign and malignant breast tumor groups(PASM= 0.014, Pcontrast= 0.019, Pcorrelation= 0.010, Pentropy= 0.007). The area under the ROC curve was 0.685, 0.681, 0.754, and 0.683 respectively for the positive texture variables mentioned above, and that for the combined variables(ASM, Contrast, and Entropy) was 0.802 in the model of Logistic regression. Binary Logistic regression analysis demonstrated that ASM, Contrast and Entropy were considered as thespecific imaging variables for the differential diagnosis of breast benign and malignant tumors.Conclusion The texture analysis of DWI may be a simple and effective tool in the differential diagnosis between breast benign and malignant tumors.展开更多
目的采用MRI直方图纹理分析技术评估颞下颌关节紊乱病(temporomandibular disorder,TMD)患者的翼外肌功能变化。方法纳入2016年5月至2020年4月于解放军总医院海南医院放射科门诊就诊的28例TMD患者,男性15例,女性13例,年龄(26.2±12...目的采用MRI直方图纹理分析技术评估颞下颌关节紊乱病(temporomandibular disorder,TMD)患者的翼外肌功能变化。方法纳入2016年5月至2020年4月于解放军总医院海南医院放射科门诊就诊的28例TMD患者,男性15例,女性13例,年龄(26.2±12.1)岁(15~62岁);同时门诊招募13名颞下颌关节正常志愿者,男性6名,女性7名,年龄(23.5±3.3)岁(20~30)岁。所有受试者均进行双侧颞下颌关节MRI扫描,根据关节盘移位情况分为TMD关节盘位置正常侧(disc without displacement,TMD-DwoD)组(38侧)、TMD关节盘不可复性向前移位侧(disc displacement without reduction,TMD-DDwoR)组(18侧)、正常对照关节盘位置正常侧(normal control-Disc without displacement,NC-DwoD)组(26侧)。采用感兴趣区法测量闭口位时颞下颌关节翼外肌上肌腹与下肌腹面积、平均信号强度、信号强度变异系数、偏度及峰度等直方图纹理参数。结果翼外肌上腹TMD-DwoD组的面积[(67.36±30.23)mm2]显著小于NC-DwoD组[(91.42±45.01)mm2](P<0.05),与TMD-DDwoR组[(72.27±37.53)mm2]间差异无统计学意义(P>0.05);TMD-DwoD组及TMD-DDwoR组的平均信号强度(分别为304.20±29.90和315.06±40.20)均显著大于NC-DwoD组(269.79±25.54)(P<0.05);TMD-DwoD组变异系数(8.89±2.60)显著大于NC-DwoD组及TMD-DDwoR组(分别为6.76±1.82和7.63±1.62)(P<0.05);组间峰度、偏度差异均无统计学意义(P>0.05)。TMD-DwoD组及TMD-DDwoR组的翼外肌下腹平均信号强度(分别为286.69±23.48和275.98±30.55)显著大于NC-DwoD组(243.56±17.04)(P<0.05);TMD-DwoD组及TMD-DDwoR组变异系数(分别为9.96±2.24和10.25±1.96)均显著大于NC-DwoD组(8.49±1.94)(P<0.05);TMD-DwoD组及TMD-DDwoR组的偏度(分别为0.90±0.94和0.73±0.97)显著小于NC-DwoD组(1.40±1.03)(P<0.05);3组组间的翼外肌下腹面积、峰度差异无统计学意义(P>0.05)。结论MRI直方图纹理分析技术可初步作为颞下颌关节紊乱病患者翼外肌功能的评价工具。展开更多
文摘目的通过MRI评估颞下颌关节紊乱病患者髁突位置及形态的变化,为临床提供参考。方法对2011年11月至2019年4月解放军总医院放射科及解放军总医院海南医院放射科门诊就诊的137例临床诊断为颞下颌关节紊乱病的患者[年龄(37.5±16.1)岁,男性39例,女性98例]进行颞下颌关节MRI扫描,根据关节盘移位情况分为关节盘位置正常组(disc without displacement,DWoD)(185侧关节),关节盘可复性前移位组(anterior disc displacement with reduction,DDWR)(17侧关节)及关节盘不可复性前移位组(disc displacement without reduction,DDWoR)(72侧关节),观察颞下颌关节髁突位置(前位、中立位及后位)和形态(卵圆形、扁平形及鸟嘴形),并在横轴位T2WI图像上测量髁突长轴和短轴长度。根据双侧关节盘移位情况分为正常组(74例)、单侧移位组(40例)及双侧移位组(23例),并在横断面T2WI上测量并比较3组髁间角。结果DWoD组、DDWR组和DDWoR组髁突位置差异无统计学意义(χ^2=7.435,P=0.115)。DWoD组扁平形髁突发生率[83.9%(115/137)]显著高于DDWoR组[50.7%(34/67)](P<0.05),DWoD组鸟嘴形髁突发生率[16.1%(22/137)]显著低于DDWoR组[49.3%(33/67)](P<0.05)。DWoD组髁突长轴长度[(17.2±2.4)mm]显著大于DDWR组[(15.4±2.0)mm]和DDWoR组[(14.7±2.7)mm](P<0.05)。DWoD组髁突短轴长度[(7.3±1.2)mm]显著大于DDWR组[(6.5±1.3)mm]和DDWoR组[(6.1±1.4)mm](P<0.05)。正常组、单侧移位组髁间角(分别为136°±13°和132°±14°)均显著大于双侧移位组(124°±17°)(P<0.05)。结论颞下颌关节紊乱病患者群中颞下颌关节盘移位患者可见髁突形态显著改变。
文摘Objective To investigate the difference in texture features on diffusion weighted imaging(DWI) images between breast benign and malignant tumors.Methods Patients including 56 with mass-like breast cancer, 16 with breast fibroadenoma, and 4 with intraductal papilloma of breast treated in the Hainan Hospital of Chinese PLA General Hospital were retrospectively enrolled in this study, and allocated to the benign group(20 patients) and the malignant group(56 patients) according to the post-surgically pathological results. Texture analysis was performed on axial DWI images, and five characteristic parameters including Angular Second Moment(ASM), Contrast, Correlation, Inverse Difference Moment(IDM), and Entropy were calculated. Independent sample t-test and Mann-Whitney U test were performed for intergroup comparison. Regression model was established by using Binary Logistic regression analysis, and receiver operating characteristic curve(ROC) analysis was carried out to evaluate the diagnostic efficiency. Results The texture features ASM, Contrast, Correlation and Entropy showed significant differences between the benign and malignant breast tumor groups(PASM= 0.014, Pcontrast= 0.019, Pcorrelation= 0.010, Pentropy= 0.007). The area under the ROC curve was 0.685, 0.681, 0.754, and 0.683 respectively for the positive texture variables mentioned above, and that for the combined variables(ASM, Contrast, and Entropy) was 0.802 in the model of Logistic regression. Binary Logistic regression analysis demonstrated that ASM, Contrast and Entropy were considered as thespecific imaging variables for the differential diagnosis of breast benign and malignant tumors.Conclusion The texture analysis of DWI may be a simple and effective tool in the differential diagnosis between breast benign and malignant tumors.
文摘目的采用MRI直方图纹理分析技术评估颞下颌关节紊乱病(temporomandibular disorder,TMD)患者的翼外肌功能变化。方法纳入2016年5月至2020年4月于解放军总医院海南医院放射科门诊就诊的28例TMD患者,男性15例,女性13例,年龄(26.2±12.1)岁(15~62岁);同时门诊招募13名颞下颌关节正常志愿者,男性6名,女性7名,年龄(23.5±3.3)岁(20~30)岁。所有受试者均进行双侧颞下颌关节MRI扫描,根据关节盘移位情况分为TMD关节盘位置正常侧(disc without displacement,TMD-DwoD)组(38侧)、TMD关节盘不可复性向前移位侧(disc displacement without reduction,TMD-DDwoR)组(18侧)、正常对照关节盘位置正常侧(normal control-Disc without displacement,NC-DwoD)组(26侧)。采用感兴趣区法测量闭口位时颞下颌关节翼外肌上肌腹与下肌腹面积、平均信号强度、信号强度变异系数、偏度及峰度等直方图纹理参数。结果翼外肌上腹TMD-DwoD组的面积[(67.36±30.23)mm2]显著小于NC-DwoD组[(91.42±45.01)mm2](P<0.05),与TMD-DDwoR组[(72.27±37.53)mm2]间差异无统计学意义(P>0.05);TMD-DwoD组及TMD-DDwoR组的平均信号强度(分别为304.20±29.90和315.06±40.20)均显著大于NC-DwoD组(269.79±25.54)(P<0.05);TMD-DwoD组变异系数(8.89±2.60)显著大于NC-DwoD组及TMD-DDwoR组(分别为6.76±1.82和7.63±1.62)(P<0.05);组间峰度、偏度差异均无统计学意义(P>0.05)。TMD-DwoD组及TMD-DDwoR组的翼外肌下腹平均信号强度(分别为286.69±23.48和275.98±30.55)显著大于NC-DwoD组(243.56±17.04)(P<0.05);TMD-DwoD组及TMD-DDwoR组变异系数(分别为9.96±2.24和10.25±1.96)均显著大于NC-DwoD组(8.49±1.94)(P<0.05);TMD-DwoD组及TMD-DDwoR组的偏度(分别为0.90±0.94和0.73±0.97)显著小于NC-DwoD组(1.40±1.03)(P<0.05);3组组间的翼外肌下腹面积、峰度差异无统计学意义(P>0.05)。结论MRI直方图纹理分析技术可初步作为颞下颌关节紊乱病患者翼外肌功能的评价工具。
