为满足钠离子电池的实际应用,本文采用一种低能耗方法合成了层状NaCrO_(2)正极材料.合成的O3型NaCrO_(2)正极材料即使在高温下也表现出优异的倍率性能.在60℃,100 C倍率下测试时比容量高达47.4 mA h g^(-1),这是由于适当的高温促进了Na^...为满足钠离子电池的实际应用,本文采用一种低能耗方法合成了层状NaCrO_(2)正极材料.合成的O3型NaCrO_(2)正极材料即使在高温下也表现出优异的倍率性能.在60℃,100 C倍率下测试时比容量高达47.4 mA h g^(-1),这是由于适当的高温促进了Na^(+)的扩散.然而,与室温下良好的循环性能相比,高温循环过程中NaCrO_(2)发生了复杂的不可逆结构演变,这导致NaCrO_(2)高温循环性能下降.这项工作将推动具有优异倍率性能、尤其是优异高温倍率性能的钠离子电池层状氧化物正极材料的产业化发展,同时加深对层状氧化物正极材料高温容量衰减机制的理解.展开更多
Nano-sized LiFePO_4·Li_3V_2（PO_4）_3/C was synthesized via a sol-gel route combining with freeze-drying. X-ray diffraction results show that this composite mainly consists of olivine Li Fe PO4 and monoclinic Li3...Nano-sized LiFePO_4·Li_3V_2（PO_4）_3/C was synthesized via a sol-gel route combining with freeze-drying. X-ray diffraction results show that this composite mainly consists of olivine Li Fe PO4 and monoclinic Li3 V2（PO4）3 phases with small amounts of V-doped LiFePO_4 and Fe-doped Li_3V_2（PO_4）_3. The magnetic properties of LiFePO_4·Li_3V_2（PO_4）_3/C are significantly different from LiFePO_4/C. Trace quantities of ferromagnetic impurities and Fe_2P are verified in LiFePO_4/C and LiFePO_4·Li_3V_2（PO_4）_3/C by magnetic tests, respectively. LiFePO_4·Li_3 V_2（PO_4）_3/C possesses relatively better rate capacities and cyclic stabilities, especially at high charge-discharge rates.The initial discharge capacities are 136.4 and 130.0 mA h g^（-1）,and the capacity retentions are more than 98% after 100 cycles at 2C and 5C, respectively, remarkably better than those of LiFePO_4/C. The excellent electrochemical performances are ascribed to the mutual doping of V^（3＋）and Fe^（2＋）, complementary advantages of LiFePO_4 and Li_3V_2（PO_4）_3 phases, the residual high-ordered carbon and Fe_2P with outstanding electric conductivity in the nanocomposite.展开更多
The increasing demand for portable electronic devices and hybrid electric vehicles stimulates the develop- ment of supercapacitors as an advanced energy storage system. Here, we demonstrate a binder-free nickel hydrox...The increasing demand for portable electronic devices and hybrid electric vehicles stimulates the develop- ment of supercapacitors as an advanced energy storage system. Here, we demonstrate a binder-free nickel hydroxide@nano- porous gold/Ni foam （Ni（OH）2@NPG/Ni foam） electrode for high-performance supercapacitors, which is prepared by a facile three-step fabrication route including electrodeposition of Au-Sn alloy on Ni foam, chemical dealloying of Sn and electrodepostion of Ni（OH）2 on NPG/Ni foam. Such Ni（OH）2@NPG/Ni foam electrode is composed of a thin layer of conformable Ni（OH）2 nanoflakes supported on three-di- mensional （3D） hierarchically porous NPG/Ni foam substrate. The resulting Ni（OH）2@NPG/Ni foam electrode can offer highways for both electron transfer and ion transport and lead to an excellent electrochemical performance with an ultrahigh specific capacitance of 3,380 F g-1 at a current density of 2 A g-1. Even when the current density was increased to 50 A g-1, it still retained a high capacitance of 1,927 F g-1. The promising performance of the Ni（OH）2@NPG/Ni foam elec- trode is mainly ascribed to the 3D hierarchical porosity and the highly conductive network on the NPG/Ni foam composite current collector, as well as the conformal electrodeposition of Ni（OH）2 active material on the NPG/Ni foam, which induces the formation of interconnected porosity both on the top surface and on the inner surface of the electrode. This in- spiring electrochemical performance would make the as-de- signed electrode material become one of the most promising candidates for future electrochemical energy storage systems.展开更多
We demonstrate digital and analog devices with an Ag/MPS_(3)/Au structure based on layered MPS_(3)(M=Mn,Co,Ni)2 D materials.All devices show the bipolar behavior of resistive switching.In addition,Ag/MnPS_(3)/Au and A...We demonstrate digital and analog devices with an Ag/MPS_(3)/Au structure based on layered MPS_(3)(M=Mn,Co,Ni)2 D materials.All devices show the bipolar behavior of resistive switching.In addition,Ag/MnPS_(3)/Au and Ag/NiPS_(3)/Au devices show synaptic characteristics of potentiation and depression.The digital and analog characteristics of resistance states enable Ag/MPS_(3)/Au devices to work as both binary memory and artificial synapse devices.The Ag/MPS_(3)/Au memory devices are promising for applications of flexible eye-like and brain-like systems on a chip when they are integrated with photodetectors and FETs composed of full MPS_(3) materials.展开更多
针对锂硫电池中单质硫导电性差和中间产物多硫化锂易溶解于电解液的问题,本文以多壁碳纳米管为导电骨架负载硫,再在其表面包覆一层MnO_2,制备了高性能MnO_2@MWCNT-S的复合材料。多壁碳纳米管可以提供电子导电路径,提高电极材料的导电性...针对锂硫电池中单质硫导电性差和中间产物多硫化锂易溶解于电解液的问题,本文以多壁碳纳米管为导电骨架负载硫,再在其表面包覆一层MnO_2,制备了高性能MnO_2@MWCNT-S的复合材料。多壁碳纳米管可以提供电子导电路径,提高电极材料的导电性能,而表面的MnO_2对多硫化物有很强的化学吸附作用,可以抑制多硫化物的溶解,从而提高活性材料利用率。通过扫描电子显微镜(SEM)和透射电子显微镜(TEM)表征,发现硫均匀负载在碳纳米管上,它们的表面包覆有一层MnO_2。经热重分析(TGA)测试,MnO_2@MWCNT-S复合材料中硫的含量为58.4%。电化学测试结果表明,MnO_2显著提高了电极材料的首次充放电比容量,并能有效地延缓多硫化物的溶解。MnO_2@MWCNT-S复合材料在0.1 C倍率下,首次充放电比容量达到1148.98 m A·h/g,100次充放电后容量依然保持在560.04 m A·h/g。展开更多
The purpose of this study was to investigate the potential antitumor efficacy of conjugated linoleic acid-paclitaxel （CLA-PTX） on B16-F10 melanoma cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis...The purpose of this study was to investigate the potential antitumor efficacy of conjugated linoleic acid-paclitaxel （CLA-PTX） on B16-F10 melanoma cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis and cell cycle of CLA-PTX were investigated. The in vitro cellular uptake of CLA-PTX in B16-F10 cells was also analyzed. The antitumor activity of CLA-PTX was also evaluated in B16-F10 tumor-bearing C57BL6/N mice in vivo. The in vitro cytotoxicity results showed that the IC50 of the CLA-PTX is （4.25±0.43） μM, compared with that of （6.70±0.80） μM in PTX treatment group （P〈0.01）. CLA-PTX increased the percentage of total apoptotic cells compared with that of control and PTX treatment groups （P〈0.01）. Compared with untreated cells, CLA-PTX arrested cell cycle progression at the S phase, whereas PTX caused accumulation of cell at GE-M phase both along with the reduction of the cellular fraction arrested at the G1 phase. The amount of cellular uptake of CLA-PTX was significantly higher than that of PTX （P〈0.01）. The in vivo antitumor activity of CLA-PTX was significantly higher than that of control and PTX treatment groups （P〈0.01 or P〈0.05）. In conclusion, our study demonstrated that CLA-PTX has significant antitumor activity in B 16-F 10 cell line.展开更多
Considering the results of our previous research that conjugated linoleic acid mixture-paclitaxel （CLA-mixture-PTX） possesses anti-tumor activity against melanoma and brain glioma, the purpose of this study was to i...Considering the results of our previous research that conjugated linoleic acid mixture-paclitaxel （CLA-mixture-PTX） possesses anti-tumor activity against melanoma and brain glioma, the purpose of this study was to investigate the potential anti-tumor efficacy of cis-9, trans- 1 1-conjugated linoleic acid-paclitaxel （c9, tl 1-CLA-PTX） and trans- 1 O, cis- 12-conjugated linoleic acid-paclitaxel （tl0, c12-CLA-PTX） on MCF-7 breast cancer cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis induction effect and cell cycle arresting effect of c9, t1 1-CLA-PTX and t10, c12-CLA-PTX were investigated. The in vitro cellular uptake of c9, tl 1-CLA-PTX and tl0, cl2-CLA-PTX in MCF-7 cells were also analyzed. Besides, the anti-tumor activity of c9, tl 1-CLA-PTX and tl0, cl2-CLA-PTX was evaluated in MCF-7 tumor bearing nude mice in vivo. The in vitro cytotoxicity results showed that the value of ICs0 of the tl 0, c l2-CLA-PTX is （0.17±0.02） μM, compared with that of （1.08±0.15） μM in CLA-mixture-PTX and （6.50±1.20） μM in c9, tl 1-CLA-PTX treatment group （P〈0.01）. Both tl0, cl2-CLA-PTX and c9, t l 1-CLA-PTX increased the percentage of total apoptotic cells compared with that of control （P〈0.01）. And the rank of apoptosis induction efficacy was t 10, c 12-CLA-PTX〉CLA-mixture-PTX〉c9, t 11-CLA-PTX （P〈0.01）. Compared with untreated cells, the tl0, c12-CLA-PTX and c9, tl 1-CLA-PTX arrested cell cycle progression at the S and G2-M phase. The amount of cellular uptake of t 10, c 12-CLA-PTX was significantly higher than that of CLA-mixture-PTX （P〈0.01）, which was significantly higher than that of c9, t1 1-CLA-PTX （P〈0.01）. The rank of in vivo anti-tumor activity was tl0, c12-CLA-PTX〉CLA-mixture-PTX〉 c9, t1 1-CLA-PTX （P〈0.01）. In conclusion, our study demonstrated that both tl0, cl2-CLA-PTX and c9, tl 1-CLA-PTX has significant anti-tumor activity in MCF-7 cell line. And while c9, tl 1-CLA-PTX showed weaker inhibitory effect than CLA-mixture-PTX, str展开更多
基金supported by the National Natural Science Foundation of China (21673051)the Natural Science Foundation of Guangdong Province of China (2021A1515010388)。
文摘为满足钠离子电池的实际应用,本文采用一种低能耗方法合成了层状NaCrO_(2)正极材料.合成的O3型NaCrO_(2)正极材料即使在高温下也表现出优异的倍率性能.在60℃,100 C倍率下测试时比容量高达47.4 mA h g^(-1),这是由于适当的高温促进了Na^(+)的扩散.然而,与室温下良好的循环性能相比,高温循环过程中NaCrO_(2)发生了复杂的不可逆结构演变,这导致NaCrO_(2)高温循环性能下降.这项工作将推动具有优异倍率性能、尤其是优异高温倍率性能的钠离子电池层状氧化物正极材料的产业化发展,同时加深对层状氧化物正极材料高温容量衰减机制的理解.
基金supported by the National Natural Science Foundation of China (21673051)Guangdong Province Science & Technology Bureau (2014A010106029, 2014B010106005 and 2016A010104015)+3 种基金Guangzhou Science & Innovative Committee (201604030037)the Youth Foundation of Guangdong University of Technology (252151038)the link project of the National Natural Science Foundation of China and Guangdong Province (U1401246)the Science and Technology Program of Guangzhou City of China (201508030018)
文摘Nano-sized LiFePO_4·Li_3V_2（PO_4）_3/C was synthesized via a sol-gel route combining with freeze-drying. X-ray diffraction results show that this composite mainly consists of olivine Li Fe PO4 and monoclinic Li3 V2（PO4）3 phases with small amounts of V-doped LiFePO_4 and Fe-doped Li_3V_2（PO_4）_3. The magnetic properties of LiFePO_4·Li_3V_2（PO_4）_3/C are significantly different from LiFePO_4/C. Trace quantities of ferromagnetic impurities and Fe_2P are verified in LiFePO_4/C and LiFePO_4·Li_3V_2（PO_4）_3/C by magnetic tests, respectively. LiFePO_4·Li_3 V_2（PO_4）_3/C possesses relatively better rate capacities and cyclic stabilities, especially at high charge-discharge rates.The initial discharge capacities are 136.4 and 130.0 mA h g^（-1）,and the capacity retentions are more than 98% after 100 cycles at 2C and 5C, respectively, remarkably better than those of LiFePO_4/C. The excellent electrochemical performances are ascribed to the mutual doping of V^（3＋）and Fe^（2＋）, complementary advantages of LiFePO_4 and Li_3V_2（PO_4）_3 phases, the residual high-ordered carbon and Fe_2P with outstanding electric conductivity in the nanocomposite.
基金financially supported by the National Natural Science Foundation of China (21673051,51604086)the Guangdong Science and Technology Department (2016A010104015)+4 种基金the Pearl River Scholar Funded Scheme of Guangdong Province Universities and Colleges (2015)the Science and Technology Program of Guangzhou (201604030037)the 'One-hundred Talents plan' (220418056)the 'One-hundred Young Talents plan' (220413126)the Youth Foundation (252151038) of Guangdong University of Technology
文摘The increasing demand for portable electronic devices and hybrid electric vehicles stimulates the develop- ment of supercapacitors as an advanced energy storage system. Here, we demonstrate a binder-free nickel hydroxide@nano- porous gold/Ni foam （Ni（OH）2@NPG/Ni foam） electrode for high-performance supercapacitors, which is prepared by a facile three-step fabrication route including electrodeposition of Au-Sn alloy on Ni foam, chemical dealloying of Sn and electrodepostion of Ni（OH）2 on NPG/Ni foam. Such Ni（OH）2@NPG/Ni foam electrode is composed of a thin layer of conformable Ni（OH）2 nanoflakes supported on three-di- mensional （3D） hierarchically porous NPG/Ni foam substrate. The resulting Ni（OH）2@NPG/Ni foam electrode can offer highways for both electron transfer and ion transport and lead to an excellent electrochemical performance with an ultrahigh specific capacitance of 3,380 F g-1 at a current density of 2 A g-1. Even when the current density was increased to 50 A g-1, it still retained a high capacitance of 1,927 F g-1. The promising performance of the Ni（OH）2@NPG/Ni foam elec- trode is mainly ascribed to the 3D hierarchical porosity and the highly conductive network on the NPG/Ni foam composite current collector, as well as the conformal electrodeposition of Ni（OH）2 active material on the NPG/Ni foam, which induces the formation of interconnected porosity both on the top surface and on the inner surface of the electrode. This in- spiring electrochemical performance would make the as-de- signed electrode material become one of the most promising candidates for future electrochemical energy storage systems.
基金Project supported by the National Key R&D Program of China(Grant Nos.2017YFA0206200 and 2018YFB2202601)the National Natural Science Foundation of China(Grant Nos.61674173,61834005,and 61902443)。
文摘We demonstrate digital and analog devices with an Ag/MPS_(3)/Au structure based on layered MPS_(3)(M=Mn,Co,Ni)2 D materials.All devices show the bipolar behavior of resistive switching.In addition,Ag/MnPS_(3)/Au and Ag/NiPS_(3)/Au devices show synaptic characteristics of potentiation and depression.The digital and analog characteristics of resistance states enable Ag/MPS_(3)/Au devices to work as both binary memory and artificial synapse devices.The Ag/MPS_(3)/Au memory devices are promising for applications of flexible eye-like and brain-like systems on a chip when they are integrated with photodetectors and FETs composed of full MPS_(3) materials.
文摘针对锂硫电池中单质硫导电性差和中间产物多硫化锂易溶解于电解液的问题,本文以多壁碳纳米管为导电骨架负载硫,再在其表面包覆一层MnO_2,制备了高性能MnO_2@MWCNT-S的复合材料。多壁碳纳米管可以提供电子导电路径,提高电极材料的导电性能,而表面的MnO_2对多硫化物有很强的化学吸附作用,可以抑制多硫化物的溶解,从而提高活性材料利用率。通过扫描电子显微镜(SEM)和透射电子显微镜(TEM)表征,发现硫均匀负载在碳纳米管上,它们的表面包覆有一层MnO_2。经热重分析(TGA)测试,MnO_2@MWCNT-S复合材料中硫的含量为58.4%。电化学测试结果表明,MnO_2显著提高了电极材料的首次充放电比容量,并能有效地延缓多硫化物的溶解。MnO_2@MWCNT-S复合材料在0.1 C倍率下,首次充放电比容量达到1148.98 m A·h/g,100次充放电后容量依然保持在560.04 m A·h/g。
基金National Natural Science Foundation of China(Grant No.81172992)the National Basic Research Program of China(973 Program,Grant No.2009CB930300)Innovation Team of Ministry of Education(Grant No.BMU20110263)
文摘The purpose of this study was to investigate the potential antitumor efficacy of conjugated linoleic acid-paclitaxel （CLA-PTX） on B16-F10 melanoma cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis and cell cycle of CLA-PTX were investigated. The in vitro cellular uptake of CLA-PTX in B16-F10 cells was also analyzed. The antitumor activity of CLA-PTX was also evaluated in B16-F10 tumor-bearing C57BL6/N mice in vivo. The in vitro cytotoxicity results showed that the IC50 of the CLA-PTX is （4.25±0.43） μM, compared with that of （6.70±0.80） μM in PTX treatment group （P〈0.01）. CLA-PTX increased the percentage of total apoptotic cells compared with that of control and PTX treatment groups （P〈0.01）. Compared with untreated cells, CLA-PTX arrested cell cycle progression at the S phase, whereas PTX caused accumulation of cell at GE-M phase both along with the reduction of the cellular fraction arrested at the G1 phase. The amount of cellular uptake of CLA-PTX was significantly higher than that of PTX （P〈0.01）. The in vivo antitumor activity of CLA-PTX was significantly higher than that of control and PTX treatment groups （P〈0.01 or P〈0.05）. In conclusion, our study demonstrated that CLA-PTX has significant antitumor activity in B 16-F 10 cell line.
基金National Natural Science Foundation of China (Grant No.81172992)the National Basic Research Program of China (973 Program,Grant No.2013CB932501)Innovation Team of Ministry of Education (Grant No.BMU20110263)
文摘Considering the results of our previous research that conjugated linoleic acid mixture-paclitaxel （CLA-mixture-PTX） possesses anti-tumor activity against melanoma and brain glioma, the purpose of this study was to investigate the potential anti-tumor efficacy of cis-9, trans- 1 1-conjugated linoleic acid-paclitaxel （c9, tl 1-CLA-PTX） and trans- 1 O, cis- 12-conjugated linoleic acid-paclitaxel （tl0, c12-CLA-PTX） on MCF-7 breast cancer cell line in vitro and in vivo. The in vitro cytotoxicity, apoptosis induction effect and cell cycle arresting effect of c9, t1 1-CLA-PTX and t10, c12-CLA-PTX were investigated. The in vitro cellular uptake of c9, tl 1-CLA-PTX and tl0, cl2-CLA-PTX in MCF-7 cells were also analyzed. Besides, the anti-tumor activity of c9, tl 1-CLA-PTX and tl0, cl2-CLA-PTX was evaluated in MCF-7 tumor bearing nude mice in vivo. The in vitro cytotoxicity results showed that the value of ICs0 of the tl 0, c l2-CLA-PTX is （0.17±0.02） μM, compared with that of （1.08±0.15） μM in CLA-mixture-PTX and （6.50±1.20） μM in c9, tl 1-CLA-PTX treatment group （P〈0.01）. Both tl0, cl2-CLA-PTX and c9, t l 1-CLA-PTX increased the percentage of total apoptotic cells compared with that of control （P〈0.01）. And the rank of apoptosis induction efficacy was t 10, c 12-CLA-PTX〉CLA-mixture-PTX〉c9, t 11-CLA-PTX （P〈0.01）. Compared with untreated cells, the tl0, c12-CLA-PTX and c9, tl 1-CLA-PTX arrested cell cycle progression at the S and G2-M phase. The amount of cellular uptake of t 10, c 12-CLA-PTX was significantly higher than that of CLA-mixture-PTX （P〈0.01）, which was significantly higher than that of c9, t1 1-CLA-PTX （P〈0.01）. The rank of in vivo anti-tumor activity was tl0, c12-CLA-PTX〉CLA-mixture-PTX〉 c9, t1 1-CLA-PTX （P〈0.01）. In conclusion, our study demonstrated that both tl0, cl2-CLA-PTX and c9, tl 1-CLA-PTX has significant anti-tumor activity in MCF-7 cell line. And while c9, tl 1-CLA-PTX showed weaker inhibitory effect than CLA-mixture-PTX, str
