带状疱疹后遗神经痛(PHN)是一种由病毒感染导致的皮肤病。病毒侵犯神经,致使神经元细胞受损,疼痛阈值及中枢敏化下降,进而引发神经性疼痛,其疼痛性质较为剧烈,严重影响患者生活。本病多发于老年及久病体虚者,病机主要为本虚标实,固采用...带状疱疹后遗神经痛(PHN)是一种由病毒感染导致的皮肤病。病毒侵犯神经,致使神经元细胞受损,疼痛阈值及中枢敏化下降,进而引发神经性疼痛,其疼痛性质较为剧烈,严重影响患者生活。本病多发于老年及久病体虚者,病机主要为本虚标实,固采用火针扶正祛邪,结合火罐放血引邪外出。本文介绍应用火针结合火罐放血治疗PHN的医案一则。Postherpetic neuralgia (PHN) is a skin disease caused by viral infection. Due to virus invasion of nerves, neuronal cells are damaged, pain thresholds and central sensitization decrease, leading to neuropathic pain, which is more severe and seriously affects the patient’s life. This disease is more common in the elderly and those who suffer from prolonged physical deficiency. The main pathogenesis is the deficiency of the original body and the excess of the actual body. Fire acupuncture is used to support the right and eliminate evil, and combined with cupping to release blood and induce evil to go out. This article introduces a medical case of using fire needle combined with cupping for the treatment of PHN.展开更多
针对水产品农药残留分析过程中基质干扰强的现状,本研究利用多壁碳纳米管(MWCNTs)和海藻酸钠(SAL)制备了一种MWCNTs-SAL复合净化材料,建立了高效液相色谱-三重四极杆/复合线性离子阱质谱(HPLC-QTRAP-MS/MS)快速测定水产品中66种农药残...针对水产品农药残留分析过程中基质干扰强的现状,本研究利用多壁碳纳米管(MWCNTs)和海藻酸钠(SAL)制备了一种MWCNTs-SAL复合净化材料,建立了高效液相色谱-三重四极杆/复合线性离子阱质谱(HPLC-QTRAP-MS/MS)快速测定水产品中66种农药残留的分析方法。采用电喷雾装置将MWCNTs和SAL的复合溶液快速喷入CaCl2溶液中进行交联,制备MWCNTs-SAL复合材料。将乙腈作为提取溶剂,基于推杆式震荡型净化技术对提取液进行净化。采用C18RRHD色谱柱(150 mm×3.0 mm, 1.8μm)对目标化合物进行分离,在多反应监测(MRM)模式下采集质谱数据,使用基质匹配混合标准溶液进行定量分析。实验比较了MWCNTs-SAL填料与商品化填料对南美白对虾提取液的净化效果,并考察了MWCNTs-SAL用量对目标化合物净化效果的影响。实验结果表明,66种农药在0.5~50μg/L内线性关系良好,相关系数均>0.99,检出限和定量限分别为0.5~1μg/kg和1~2μg/kg;在低、中、高3个加标水平下,66种目标化合物的回收率为64.1%~107.3%,日内和日间精密度均小于20.4%。该方法经济快速,简便高效,具有较高的灵敏度和重复性,是水产品中农药残留分析的可行方法。展开更多
文摘带状疱疹后遗神经痛(PHN)是一种由病毒感染导致的皮肤病。病毒侵犯神经,致使神经元细胞受损,疼痛阈值及中枢敏化下降,进而引发神经性疼痛,其疼痛性质较为剧烈,严重影响患者生活。本病多发于老年及久病体虚者,病机主要为本虚标实,固采用火针扶正祛邪,结合火罐放血引邪外出。本文介绍应用火针结合火罐放血治疗PHN的医案一则。Postherpetic neuralgia (PHN) is a skin disease caused by viral infection. Due to virus invasion of nerves, neuronal cells are damaged, pain thresholds and central sensitization decrease, leading to neuropathic pain, which is more severe and seriously affects the patient’s life. This disease is more common in the elderly and those who suffer from prolonged physical deficiency. The main pathogenesis is the deficiency of the original body and the excess of the actual body. Fire acupuncture is used to support the right and eliminate evil, and combined with cupping to release blood and induce evil to go out. This article introduces a medical case of using fire needle combined with cupping for the treatment of PHN.
文摘针对水产品农药残留分析过程中基质干扰强的现状,本研究利用多壁碳纳米管(MWCNTs)和海藻酸钠(SAL)制备了一种MWCNTs-SAL复合净化材料,建立了高效液相色谱-三重四极杆/复合线性离子阱质谱(HPLC-QTRAP-MS/MS)快速测定水产品中66种农药残留的分析方法。采用电喷雾装置将MWCNTs和SAL的复合溶液快速喷入CaCl2溶液中进行交联,制备MWCNTs-SAL复合材料。将乙腈作为提取溶剂,基于推杆式震荡型净化技术对提取液进行净化。采用C18RRHD色谱柱(150 mm×3.0 mm, 1.8μm)对目标化合物进行分离,在多反应监测(MRM)模式下采集质谱数据,使用基质匹配混合标准溶液进行定量分析。实验比较了MWCNTs-SAL填料与商品化填料对南美白对虾提取液的净化效果,并考察了MWCNTs-SAL用量对目标化合物净化效果的影响。实验结果表明,66种农药在0.5~50μg/L内线性关系良好,相关系数均>0.99,检出限和定量限分别为0.5~1μg/kg和1~2μg/kg;在低、中、高3个加标水平下,66种目标化合物的回收率为64.1%~107.3%,日内和日间精密度均小于20.4%。该方法经济快速,简便高效,具有较高的灵敏度和重复性,是水产品中农药残留分析的可行方法。
